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Emotional lability

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https://www.readbyqxmd.com/read/29162187/methylation-of-the-glucocorticoid-receptor-gene-nuclear-receptor-subfamily-3-group-c-member-1-nr3c1-in-maltreated-and-nonmaltreated-children-associations-with-behavioral-undercontrol-emotional-lability-negativity-and-externalizing-and-internalizing-symptoms
#1
Dante Cicchetti, Elizabeth D Handley
The present study examined the effect of various dimensions of child maltreatment (i.e., developmental timing of maltreatment, number of maltreatment subtypes, and chronicity of maltreatment) on methylation of the glucocorticoid receptor gene, nuclear receptor subfamily 3, group C, member 1 (NR3C1), and investigated the associations between NR3C1 methylation and child outcomes. Participants included 534 children who attended a research summer camp program for school-aged maltreated (53.4%) and nonmaltreated (46...
December 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29157006/chronotype-description-in-search-of-a-solid-subjective-amplitude-scale
#2
Halszka Oginska, Justyna Mojsa-Kaja, Olivier Mairesse
The term "subjective circadian amplitude" refers to the range or the distinctness of diurnal variations of arousal, that is, the awareness (or lack thereof) of difference between hyper- and hypo-activation phases, the ability to volitionally modulate one's own psychophysiological state, the strength of morning-evening preferences and flexibility of the rhythm or perceived stability of the circadian phase. The complexity of this construct is the source of difficulties in research and measurement. The psychometric features of distinctness subscales of the Chronotype Questionnaire and the Caen Chronotype Questionnaire are not satisfactory...
November 20, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29145183/catastrophe-reaction-and-emotionalism
#3
Antonio Carota, Julien Bogousslavsky
The catastrophic reaction (CR; a disruptive and uncontrolled behavior triggered by anger, irritability, and hostility) and emotionalism (a condition of uncontrolled crying or laughing) are disorders of the emotional regulation and expression, the prevalence of which is underestimated in neurology. Their occurrence is an additional factor of poor outcome for neurologic patients. Although they have been recognized and completely described in their clinical manifestations more than a century ago, many issues remain unsolved regarding their pathogenesis and the respective role of the brain damage and psychological factors...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29094639/a-measure-of-emotional-regulation-and-irritability-in-children-and-adolescents-the-clinical-evaluation-of-emotional-regulation-9
#4
Jenna Pylypow, Declan Quinn, Don Duncan, Lloyd Balbuena
OBJECTIVE: To develop a scale for emotional regulation using item response theory. METHOD: Eighteen Swanson Nolan and Pelham (SNAP-IV) items that loaded on an emotional dysregulation factor were submitted to Rasch analysis. After eliminating the items that violated Rasch criteria, the remaining items were examined for reliability and validated against the Conners' emotional lability index. RESULTS: A nine-item scale for emotional regulation was developed that satisfies the Rasch model and reliably distinguishes emotionally dysregulated/irritable children and adolescents...
November 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/29073557/affect-based-profiles-of-bulimia-nervosa-the-utility-and-validity-of-indicators-assessed-in-the-natural-environment
#5
Bethany C Leraas, Kathryn E Smith, Linsey M Utzinger, Li Cao, Scott G Engel, Ross D Crosby, James E Mitchell, Stephen A Wonderlich
Theoretical conceptualizations of bulimia nervosa (BN) emphasize the role of emotion dysregulation in the development and maintenance of symptoms, which has been supported by ecological momentary assessment studies. Given the importance of affective disturbances in BN, this study aimed to classify a sample of adult women with BN (N = 130) based on primarily momentary affective indicators, including negative and positive affect, negative and positive affective lability, and depression. Participants completed baseline assessments followed by a two-week ecological momentary assessment protocol...
September 30, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29072794/effects-of-gaba-active-steroids-in-the-female-brain-with-focus-on-the-premenstrual-dysphoric-disorder
#6
REVIEW
Marie Bixo, Maja Johansson, Erika Timby, Louise Michalski, Torbjörn Bäckström
PMDD (premenstrual dysphoric disorder) afflicts 3-5% of women of childbearing age, and is characterized by recurrent negative mood symptoms, e.g. irritability, depression, anxiety and emotional lability during the luteal phase of the menstrual cycle. The etiology of PMDD is unknown, but a temporal association with circulating ovarian steroids, in particular progesterone and its metabolite allopregnanolone, during the luteal phase has been established. Allopregnanolone is a positive modulator of the GABAA receptor: it is sedative in high concentrations, but may precipitate paradoxical adverse effects on mood at levels corresponding to luteal phase concentrations in susceptible women...
October 26, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29069625/clinical-utility-of-the-dsm-5-alternative-model-for-borderline-personality-disorder-differential-diagnostic-accuracy-of-the-bfi-scid-ii-pq-and-pid-5
#7
J Christopher Fowler, Alok Madan, Jon G Allen, Michelle Patriquin, Carla Sharp, John M Oldham, B Christopher Frueh
BACKGROUND: With the publication of DSM 5 alternative model for personality disorders it is critical to assess the components of the model against evidence-based models such as the five factor model and the DSM-IV-TR categorical model. This study explored the relative clinical utility of these models in screening for borderline personality disorder (BPD). METHODS: Receiver operator characteristics and diagnostic efficiency statistics were calculated for three personality measures to ascertain the relative diagnostic efficiency of each measure...
September 12, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29055439/patient-perspectives-on-neuromyelitis-optica-spectrum-disorders-data-from-the-patientslikeme-online-community
#8
Stephanie Eaneff, Victor Wang, Morgan Hanger, Michael Levy, Maureen A Mealy, Alexander U Brandt, Daniel Eek, John N Ratchford, Fredrik Nyberg, Jonathan Goodall, Paul Wicks
BACKGROUND: Few studies have evaluated patient perspectives on neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD). OBJECTIVE: Describe patient-reported clinical and treatment experience in NMOSD and compare disease characteristics of NMOSD with those of multiple sclerosis (MS). METHODS: This retrospective, observational study included 522 members with NMO or NMOSD (hereafter collectively referred to as NMOSD) from PatientsLikeMe (PLM), an online patient community...
October 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29032119/a-systematic-review-of-safety-and-efficacy-of-systemic-corticosteroids-in-atopic-dermatitis
#9
Sherry Yu, Aaron M Drucker, Mark Lebwohl, Jonathan I Silverberg
BACKGROUND: Systemic corticosteroids are often used to treat atopic dermatitis (AD). However, few studies assessed the safety and efficacy of systemic corticosteroids in AD. OBJECTIVE: To systematically review the literature on efficacy and safety of systemic corticosteroid use (oral, intramuscular, intravenous) in AD. METHODS: PubMed, Embase, Medline, Scopus, Web of Science, and Cochrane Library were searched. We included systematic reviews, guidelines and treatment reviews of systemic corticosteroid use among patients of all ages with a diagnosis of AD (52 reviews and 12 studies)...
October 12, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28992752/comorbid-internalizing-and-externalizing-disorders-predict-lability-of-negative-emotions-among-children-with-adhd
#10
Kirsten D Leaberry, Paul J Rosen, Nicholas D Fogleman, Danielle M Walerius, Kelly E Slaughter
OBJECTIVE: A subset of children with ADHD experience more frequent, sudden, and intense shifts toward negative emotions. The current study utilized ecological momentary assessment (EMA) to provide a valid assessment of the impact of comorbid internalizing and externalizing disorders on negative emotional lability (EL) among children with ADHD. METHOD: Parents of 58, 8- to 12-year-old children with ADHD were administered a diagnostic interview to assess for ADHD and for the presence of comorbid disorders...
October 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28945932/attention-deficit-hyperactivity-disorder-symptom-clusters-differentially-predict-prenatal-health-behaviors-in-pregnant-women
#11
Heather A Jones, Laura D Eddy, Annie E Rabinovitch, Daniel J Snipes, Stephanie A Wilson, Amanda M Parks, Nicole W Karjane, Dace S Svikis
OBJECTIVE: To date, most investigations of mental health in pregnant women have focused on depression or substance use. This study aimed to (a) delineate the relationships between symptoms of attention-deficit/hyperactivity disorder (ADHD) and prenatal health behaviors and (b) explore whether the symptom clusters of ADHD differentially predict prenatal health behaviors (e.g., physical strain, healthy eating, prenatal vitamin use). METHOD: A total of 198 pregnant women (mean age = 27...
September 25, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28919330/limbic-encephalitis-with-lgi1-antibodies-in-a-14-year-old-boy
#12
M Schimmel, M C Frühwald, C G Bien
Limbic encephalitis (LE) with antibodies against leucine-rich glioma inactivated protein 1 (LGI1) is an auto-antibody mediated disorder with characteristic symptoms as dysfunction of memory, faciobrachial dystonic seizures and neuropsychiatric symptoms as emotional lability. Limbic encephalitis with LGI1 antibodies has been known so far as a disease of adults. We describe the case of a 14-year-old boy presenting with typical dysfunction of memory and LGI1 antibodies. To the best of our knowledge, this is the youngest patient with LGI1 antibody mediated limbic encephalitis described so far...
September 2, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28889962/neurobehavioral-outcomes-in-autoimmune-encephalitis
#13
Anusha K Yeshokumar, Eliza Gordon-Lipkin, Ana Arenivas, Jesse Cohen, Arun Venkatesan, Deanna Saylor, John C Probasco
This study evaluates long-term neurobehavioral function in patients with clinically diagnosed autoimmune encephalitis (AE) of various etiologies through retrospective chart review and a cross-sectional structured telephone interview. Of 77 patients meeting clinical diagnostic criteria for AE over a ten year period, 39/77 (51%) patients had known AE-associated antibodies, and 38/77 (49%) had no detected antibody. 9/77 (12%) died, and 26/77 (34%) had "poor" neurologic disability score (mRS 3-5) at the last documented follow-up...
November 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28876970/responding-to-ten-common-delirium-misconceptions-with-best-evidence-an-educational-review-for-clinicians
#14
Mark A Oldham, Nina M Flanagan, Ariba Khan, Olga Boukrina, Edward R Marcantonio
Delirium (acute confusion) is a serious, common health condition, and it predicts poor outcomes, including greater rates of mortality, institutionalization, prolonged hospitalization, and cognitive impairment. Expedient diagnosis and management are critical to address modifiable delirium causes and improve both quality of care and outcomes. Moreover, more than a third of delirium is preventable. Despite the clear significance of delirium and our increasingly sophisticated understanding of the condition, the gap between evidence and practice persists...
September 6, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28876417/prospective-study-of-patients-with-persistent-symptoms-of-dengue-in-brazil
#15
Luciana de Almeida Silva Teixeira, Fabiana Prado Dos Santos Nogueira, Gabriel Antonio Nogueira Nascentes
Dengue is an arboviral infection clinically recognized as an acute and self-limited disease. Persistence of dengue symptoms is known, but it has been little studied. The aim of this study was to characterize persistent symptoms in 113 patients with dengue followed up clinically and by laboratory testing at a tertiary hospital. Symptoms that persisted for more than 14 days were observed in 61 (54.0%) patients, and six (6.2%) of them had symptoms for 6 months or more. The persistent symptoms identified were myalgia, weakness, hair loss, memory loss, reduced resistance to physical effort, headache, reasoning problems, arthralgia, sleepiness- and emotional lability...
September 4, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28837827/pharmacotherapy-of-emotional-dysregulation-in-adults-with-adhd-a-systematic-review-and-meta-analysis
#16
REVIEW
Francesca Lenzi, Samuele Cortese, Joseph Harris, Gabriele Masi
Emotional dysregulation (ED) is a dysfunction in modifying an emotional state in an adaptive and goal oriented way, with excitability, ease anger, and mood lability. It is present in up to 70% of adults with ADHD, regardless of other comorbidities, and substantially worsens the psychosocial outcomes of the disorder. Besides fronto-parietal circuits mediating top-down control, brain regions involved in bottom-up processes (e.g., amygdala, orbitofrontal cortex, and ventral striatum) are implicated in ED. We performed a systematic review/meta-analysis of double-blind randomized controlled trials of ADHD medications to assess their effects on ED in adults with ADHD...
August 25, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28830702/cardiac-complexity-and-emotional-dysregulation-in-children
#17
Charlotte Fiskum, Tonje Grønning Andersen, Per M Aslaksen, Birgit Svendsen, Magne A Flaten, Karl Jacobsen
OBJECTIVE: Sample entropy (SampEn) gives an estimate of signal complexity in cardiac time series and can give information beyond linear heart rate variability. Lower cardiac SampEn is associated with psychopathology in adults. Emotional dysregulation is widely present in adult psychopathology and a forerunner to later mental problems in children. Therefore, this study investigated whether SampEn relates to emotional dysregulation in children. METHODS: Participants were 32 children between 9 and 13years with internalizing difficulties and 25 controls...
November 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28816380/a-daily-diary-study-of-posttraumatic-stress-experiential-avoidance-and-emotional-lability-among-inpatient-nurses
#18
James Gerhart, Elizabeth Vaclavik, Teresa A Lillis, Jacob Miner, Rory McFadden, Sean O'Mahony
No abstract text is available yet for this article.
August 17, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28778107/-current-aspects-of-premenstrual-dysphoric-disorder-a-review
#19
Theresa Beddig, Christine Kühner
This narrative review presents current aspects of diagnosis, epidemiology, aetiology and therapy of Premenstrual Dysphoric Disorder (PMDD). PMDD is characterised by emotional, physical and behavioral changes during the premenstrual phase of the menstrual cycle associated with clinically significant distress and marked impairment of psychosocial functioning. Due to its cardinal symptoms (e. g. marked affect lability and irritability), its specific cycle-dependent course and high symptom-specific stability, PMDD has been outlined as a new diagnostic category in the chapter on depressive disorders in the fifth edition of the "Diagnostic and Statistical Handbook of Mental Disorders"...
August 4, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28777981/childhood-trauma-dimensions-of-psychopathology-and-the-clinical-expression-of-bipolar-disorders-a-pathway-analysis
#20
B Etain, M Lajnef, C Henry, V Aubin, J M Azorin, F Bellivier, T Bougerol, P Courtet, S Gard, J P Kahn, C Passerieux, M Leboyer
BACKGROUND: This study aims at testing for paths from childhood abuse to clinical indicators of complexity in bipolar disorder (BD), through dimensions of affective dysregulation, impulsivity and hostility. METHOD: 485 euthymic patients with BD from the FACE-BD cohort were included from 2009 to 2014. We collect clinical indicators of complexity/severity: age and polarity at onset, suicide attempt, rapid cycling and substance misuse. Patients completed questionnaires to assess childhood emotional, sexual and physical abuses, affective lability, affect intensity, impulsivity, motor and attitudinal hostility...
December 2017: Journal of Psychiatric Research
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