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https://www.readbyqxmd.com/read/27759779/comparative-analysis-of-immunological-profiles-in-women-undergoing-conventional-and-single-port-laparoscopic-cholecystectomy
#1
Marisa de Carvalho Borges, Tharsus Dias Takeuti, Guilherme Azevedo Terra, Betânia Maria Ribeiro, Virmondes Rodrigues-Júnior, Eduardo Crema
Background: Surgical trauma triggers an important postoperative stress response characterized by significantly elevated levels of cytokines, an event that can favor the emergence of immune disorders which lead to disturbances in the patient's body defense. The magnitude of postoperative stress is related to the degree of surgical trauma. Aim: To evaluate the expression of pro-inflammatory (TNF-α, IFN-γ, IL-1β, and IL-17) and anti-inflammatory (IL-4) cytokines in patients submitted to conventional and single-port laparoscopic cholecystectomy before and 24 h after surgery...
July 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27484772/metabolic-implications-of-menstrual-cycle-length-in-non-hyperandrogenic-women-with-polycystic-ovarian-morphology
#2
Miro Šimun Alebić, Nataša Stojanović, Dinka Pavičić Baldani, Lea Smirčić Duvnjak
This cross-sectional study aimed to investigate the association between menstrual cycle lenght and metabolic parameters in non-hyperandrogenic women with polycystic ovarian morphology, n = 250. Metabolic profiles of all participants were evaluated using anthropometric parameters (body mass index, waist circumference), parameters of dyslipidemia (total cholesterol, HDL-cholesterol, triglycerides) and markers of insulin resistance (fasting insulin, homeostasis model assessment for insulin resistance index)...
August 3, 2016: Endocrine
https://www.readbyqxmd.com/read/27481573/identification-of-disease-specific-motifs-in-the-antibody-specificity-repertoire-via-next-generation-sequencing
#3
Robert J Pantazes, Jack Reifert, Joel Bozekowski, Kelly N Ibsen, Joseph A Murray, Patrick S Daugherty
Disease-specific antibodies can serve as highly effective biomarkers but have been identified for only a relatively small number of autoimmune diseases. A method was developed to identify disease-specific binding motifs through integration of bacterial display peptide library screening, next-generation sequencing (NGS) and computational analysis. Antibody specificity repertoires were determined by identifying bound peptide library members for each specimen using cell sorting and performing NGS. A computational algorithm, termed Identifying Motifs Using Next- generation sequencing Experiments (IMUNE), was developed and applied to discover disease- and healthy control-specific motifs...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26998391/systemic-immediate-hypersensitive-reactions-after-treatment-with-sweet-bee-venom-a-case-report
#4
NaYoung Jo, JeongDu Roh
OBJECTIVES: A previous study showed that bee venom (BV) could cause anaphylaxis or other hypersensitivity reactions. Although hypersensitivity reactions due to sweet bee venom (SBV) have been reported, SBV has been reported to be associated with significantly reduced sensitization compared to BV. Although no systemic immediate hypersensitive response accompanied by abnormal vital signs has been reported with respect to SBV, we report a systemic immediate hypersensitive response that we experienced while trying to use SBV clinically...
December 2015: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/25552917/effect-of-helixor-a-on-natural-killer-cell-activity-in-endometriosis
#5
In-Cheul Jeung, Youn-Jee Chung, Boah Chae, So-Yeon Kang, Jae-Yen Song, Hyun-Hee Jo, Young-Ok Lew, Jang-Heub Kim, Mee-Ran Kim
BACKGROUND AND AIM: NK cells are one of the major immune cells in endometriosis pathogenesis. While previous clinical studies have shown that helixor A to be an effective treatment for endometriosis, little is known about its mechanism of action, or its relationship with immune cells. The aim of this study is to investigate the effects of helixor A on Natural killer cell (NK cell) cytotoxicity in endometriosis MATERIALS AND METHODS: We performed an experimental study...
2015: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/25348184/immune-response-of-thalassemia-major-patients-in-indonesia-with-and-without-splenectomy
#6
COMPARATIVE STUDY
Teny T Sari, Djajadiman Gatot, Arwin A P Akib, Saptawati Bardosono, Sri R S Hadinegoro, Alida R Harahap, Ponpon S Idjradinata
AIM: to describe non-spesific and specific immune response profile in Indonesian thalassemia major with and without splenectomy. METHODS: this study was held at Thalassaemia Centre, Cipto Mangunkusumo Hospital Jakarta on September 2013-February 2014. A comparative cross sectional study was conducted in healthy, thalassemia major aged more than 12 year and seronegative HIV. They were matched in age and sex for splenectomised and non-splenectomised groups, analysing the non-spesific immune response (neutrophil count and phagocytosis) and specific immune response (count and function of cellular immunity)...
July 2014: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/24364433/occupational-exposure-to-zoonotic-agents-among-agricultural-workers-in-lombardy-region-northern-italy
#7
Ramin Tabibi, Rosana Baccalini, Alessandra Barassi, Luigi Bonizzi, Gabri Brambilla, Dario Consonni, Gianlodovico Melzi d'Eril, Luisa Romanò, Maryam Sokooti, Chiara Somaruga, Francesca Vellere, Alessandro Zanetti, Claudio Colosio
OBJECTIVES: This study was conducted in Northern Italy with the aim of defining the risk of agricultural workers' contact with biological agents through the determination of serum antibodies against selected zoonotic agents. Immunity against tetanus was also investigated. METHODS: Two groups of agricultural workers consisting of 153 animal breeders (exposed) and 46 non- breeders (controls) were included in the study. In a first group of 103 workers (89 exposed and 14 controls) the serum concentrations of antibodies against Hepatitis E Virus (HEV) were measured, whereas in the second group of 96 workers (64 exposed and 32 controls) the serum concentrations of antibodies against Leptospira spp...
2013: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/24031889/antifungal-activity-of-lectins-against-yeast-of-vaginal-secretion
#8
Bruno Severo Gomes, Ana Beatriz Sotero Siqueira, Rita de Cássia Carvalho Maia, Viviana Giampaoli, Edson Holanda Teixeira, Francisco Vassiliepe Sousa Arruda, Kyria Santiago do Nascimento, Adriana Nunes de Lima, Cristina Maria Souza-Motta, Benildo Sousa Cavada, Ana Lúcia Figueiredo Porto
Lectins are carbohydrate-binding proteins of non-imune origin. This group of proteins is distributed widely in nature and they have been found in viruses, microorganisms, plants and animals. Lectins of plants have been isolated and characterized according to their chemical, physical-chemical, structural and biological properties. Among their biological activities, we can stress its fungicidal action. It has been previously described the effect of the lectins Dviol, DRL, ConBr and LSL obtained from the seeds of leguminous plants on the growth of yeasts isolated from vaginal secretions...
April 2012: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/23983351/nutritional-content-and-a-phase-i-safety-clinical-trial-of-a-herbal-nutritional-supplement-imuniti-with-putative-immune-modulating-properties
#9
RANDOMIZED CONTROLLED TRIAL
M G Matsabisa, M P Sekhoacha, O Ibrahim, P Moodley, M Faber
The relationship between HIV and AIDS and poor nutrition has been well established. Poor nutrition hastens the progression of HIV infection to AIDS. The rising pandemic of HIV and AIDS and high toxicity associated with anti-retroviral use are major factors that have compelled research to explore traditional herbal medicines as potential alternatives or supplements to anti-retroviral agents. A Phase I clinical trial was conducted on IMUNITI Wellness Pack, a herbal product with putative immune-modulating properties...
2012: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/23069887/comparison-of-immunological-properties-of-various-bioactive-combinations
#10
Vaclav Vetvicka, Jana Vetvickova
BACKGROUND: Lately, more and more preparation of various cocktails or mixtures of bioactive modulators have been introduced. Their true activity is, however, rarely tested. AIM: To compare six commercially available, glucan-based immunostimulators. METHODS: Immunological effects of tested combinations were measured by evaluation of phagocytosis of synthetic particles by peripheral blood neutrophils, production of IL-2 by mouse splenocytes, production of superoxide anion and nitrite oxide, antibody response to imunization with ovalbumin, and NK cell activity...
September 2012: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/22512584/marine-natural-products-and-other-derivatives-as-potent-indoleamine-2-3-dioxygenase-inhibitors
#11
REVIEW
Evelyne Delfourne
Cancer cells are able to elaborate enzymatic mechanisms allowing tumors to resist or escape imune rejection. Among the enzymes involved, indoleamine 2,3-dioxygenase (IDO), an intracellular enzyme that initiates the first and rate-limiting step of tryptophan breakdown along the kynurenine pathway, has emerged as a promising molecular target for the development of new immunotherapeutic anticancer agents. This review summarizes the synthesis and IDO activities of the different classes of marine and other inhibitors reported so far...
September 1, 2012: Mini Reviews in Medicinal Chemistry
https://www.readbyqxmd.com/read/22415069/briefs-on-insulin-and-innate-immune-response
#12
Karen K S Sunahara, Paulina Sannomiya, Joilson O Martins
Insulin is a pivotal regulator of glucose metabolism and exerts an important anabolic function throughout the body. Insulin commands the glucose uptake by the cells and might control the processes in which there is need for energy such as mitogenesis and gene transcription. In certain conditions, diabetes mellitus for example, when insulin is diminished, the homeostasis of many tissues and organs are broken what can lead to a higher mortality due to an enhanced susceptibility to infections. This vulnerability to infections can partially be explained by a change in response to inflammation...
2012: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/21630073/refractory-anemia-as-a-presenting-feature-of-microscopic-polyangiitis-a-rare-vasculitis-in-children
#13
Geetanjali Jindal, Sanjay D Cruz, R P S Punia, Ravinder Kaur
Microcytic anemia refractory to usual supplementation is an important clue to an alternative diagnosis. Accompanying pulmonary and renal involvement during the disease course suggests a multisystem disease. Small-vessel vasculitis should be suspected in any patient who presents with a multisystem disease that is not caused by an infectious or malignant process. Among these, antineutrophilic cytoplasmic antibodies (ANCA)-associated vasculitis is a distinct subclass involving anti-neutrophil cytoplasmic antibody (ANCA) as the common pathogenesis...
October 2011: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/20853621/-physiological-and-pathological-role-of-adipose-tissue-innate-immune-system-receptors
#14
REVIEW
V Shvarts
The data of TLR-4 and TLR-2 existance in adipose tissue cells is presented in the review, their signal pathway is described, and an idea of physiological and pathological role of innate immune system receptors is given proof. TLRs activation leads to insulin resistance of adipose, hepatic and muscle cells, which increases glucose and lipids level in blood. This reaction is defined as a condition of physiological insulin resistance, which role is in providing immune processes with energetic and plastic substances...
July 2010: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
https://www.readbyqxmd.com/read/20662452/-breast-carcinoma-in-a-female-patient-after-kidney-transplantation-a-case-review
#15
M Vachtová, V Treska, B Sůvová, O Hes, D Ebelenderová
INTRODUCTION: Kidney transplantation improves the quality of life in patients with chronic renal insufficiency. Immunosuppression therapy has a significant impact on good quality long-term function of the transplanted kidney and on the long-term survival of the patients. However, long-term administration of immunosuppressives may be associated with a number of complications. These, in particular, include infectious events, as well as increased rates of malignancies in the population of transplantation patients, compared to normal population...
November 2009: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/20518334/-effect-analysis-on-moh-who-luxembourg-project-of-strengthening-cold-chain-and-childhood-immunization-service-quality-project-in-qinghai-province
#16
Ke-zhong A, Yong-ji Zhang, Biao Guo
OBJECTIVE: To improve the cold chain systematic management and the quality of immunization through implementing MOH-WHO-Luxembourg project of strengthening cold chain and childhood immunization service quality in Qinghai province. METHODS: Analysis and comparison of relevant information of cold chain equipment, disease surveillance and immunization management. RESULTS: 47% township had transportation facility for immunization programs, 61% township hospital cold-chain equipment was renewed, 30% township hospitals cold-chain equipment updated...
December 2009: Zhongguo Yi Miao He Mian Yi
https://www.readbyqxmd.com/read/19565007/polymorphism-of-the-fcgamma-receptor-iia-and-malaria-morbidity
#17
Erika Martins Braga, Kézia Katiani Gorza Scopel, Natália Tiemi Komatsu, Mônica da Silva-Nunes, Marcelo Urbano Ferreira
Fc receptors (FcRs) are expressed on the surface of all types of cells of the immune system. They bind the Fc portion of immunoglobulin (Ig), thereby bridging specific antigen recognition by antibodies with cellular effector mechanisms. FcgammaRIIA, one of the three receptors for human IgG, is a low-affinity receptor for monomeric IgG, but binds IgG immune complexes efficiently. FcgammaRIIA is believed to play a major role in eliciting monocyte- and macrophage-mediated effector responses against blood-stage malaria parasites...
2005: Journal of Molecular and Genetic Medicine: An International Journal of Biomedical Research
https://www.readbyqxmd.com/read/18669231/-accidental-asymptomatic-infections-with-hephatitis-b-virus-and-testing-on-hbv-markers-of-healthcare-personnel
#18
Enes Sacić, Dzana Sacić
Healthcare personnel is being highly exposed to the professional risk of Hephatitis B virus infection by accidental professional injuries, where direct contact with patients blood occurs. Number of researches indicate significance and role of accidental injuries, especially over injection needles, which is leading cause for professional HBV infections occurence. HBsAg has capability to provoke imune system if applied to a man, to HBs anti-bodies production achieving thus protection from Hephatitis B Virus. Recombinant vaccine against viruse Hephatitis B achieves high imunology protection...
2008: Medicinski Arhiv
https://www.readbyqxmd.com/read/18625099/-l%C3%A3%C2%BApus-erythematosus
#19
Manuela Ferreira, Ana Bárbara Salgueiro, João Estrada, José Ramos, Lurdes Ventura, M Carmo Vale, Deolinda Barata
Systemic Lúpus Erythematosus (SLE) is an auto-imune disorder, with multiple organ involvement, characterized by vascular and connective tissue inflammation, as well as antinuclear antibodies (ANA). We report a case of a black teenager with a past of arthritis of knees, fever and astenia during the year previous to this admission. She was admitted to the Pediatric Intensive Care Unit (PICU) for bilateral Streptococcus pneumoniae pneumonia complicated by pleural effusion. She also had generalized edema and macroscopic hematúria...
March 2008: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/16830591/-humoral-imunity-to-pertussis-in-children-with-diabetes-of-type-1
#20
COMPARATIVE STUDY
A A Tarasova, M P Kostinov, E M Zaĭtsev
To determine the state of humoral immunity to pertussis in children with insulin-dependent diabetes, IgG antibodies to pertussis toxin (PT) were determined in blood serum samples by means of EIA. In a group of children aged up to 6 years the highest percentage (100%) received the complete course of vaccination against pertussis with Russian adsorbed DPT vaccine, containing whole-cell pertussis monovaccine, while in a group over 6 years the complete vaccination course (3 vaccinations and 1 revaccination) had 53...
May 2006: Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii
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