Agung

BACKGROUND AND OBJECTIVE: Brain arteriovenous malformations (bAVMs) carry a risk of hemorrhage. We aim to identify factors associated with subsequent hemorrhages. METHODS: Systematic searches were conducted across the ScienceDirect, Medline, and Cochrane databases. Assessed risk factors included bAVM size, bAVM volume, hemorrhage and seizure presentations, presence of deep venous drainage, deep-seated bAVMs, associated aneurysms, and Spetzler-Martin grade. Subgroup analyses were conducted on prior treatments, hemorrhage presentation, AVM size, and type of management...

In the convergence of cultural heritage preservation and computational research, this paper presents a comprehensive dataset capturing the nuanced artistry of traditional Balinese dancing. This endeavour not only documents but also aims to protect these intricate dance movements, bridging technological advancements with rich cultural traditions. The dataset includes 1740 and 828 high-definition video recordings of female and male dancers, respectively, showcasing 24 unique dance movements. These recordings, made using multiple smartphone cameras from various perspectives, reflect the dance's complex nature and emphasize gender-based movement variations, key for detailed cultural analysis...

The small intestine and liver play important role in determining oral drug's fate. Both organs are also interconnected through enterohepatic circulation, which imply there are crosstalk through circulating factors such as signaling molecules or metabolites that may affect drug metabolism. Coculture of hepatocytes and intestinal cells have shown to increase hepatic drug metabolism, yet its crosstalk mechanism is still unclear. In this study, we aim to elucidate such crosstalk by coculturing primary human hepatocytes harvested from chimeric mouse (PXB-cells) and iPSc-derived intestinal cells in a microphysiological systems (MPS)...

This research was conducted from June to August 2023. Data and samples were collected using an exploratory survey method in four locations around the industrial area, namely PT. ASEAN Aceh Fertilizer and PT. Kertas Kraft Aceh in North Aceh Regency, while PT. Pupuk Iskandar Muda and PT. Harun NGL in Lhokseumawe Regency, Indonesia. Observations of physico-chemical parameters including measurements of salinity, bicarbonate, calcium, magnesium, nitrate, nitrite, orthophosphate, total alkalinity, and total ammonia were analyzed in the Laboratory of PT Intraco Agroindustri, Langkat Regency, North Sumatra, Indonesia...

A meta-analysis was conducted to determine the effects of herbal plant extracts on the growth performance, blood parameters, nutrient digestibility and carcase quality of farmed rabbits. A dataset was created from 33 in vivo studies comprising 121 experimental units. Statistical meta-analysis was performed using a random-effects model and linear-mixed model meta-regression using R software (v. 4.3.0). Our results showed that although supplemental herbs did not affect average daily gain (ADG) and final body weight (BW), they reduced ( P  < 0...

BACKGROUND: Doxorubicin (Dox) is effective against different types of cancers, but it poses cardiotoxic side effects, frequently resulting in irreversible heart failure. However, the complexities surrounding this cardiotoxicity, especially at sublethal dosages, remain to be fully elucidated. We investigated early cellular disruptions in response to sublethal Dox, with a specific emphasis on the role of phosphorylated calcium/calmodulin-dependent protein kinase II (CaMKII) in initiating mitochondrial dysfunction...

OBJECTIVE: The results of G1 and G4 polymorphisms as litter-size (LS) markers of ewes remain contradictory. The aim was to evaluate the impact of G1 (c.260 G>A) and G4 (c.721 G>A) polymorphisms on the LS of sheep by synthesizing data from multiple previous studies. METHODS: Data were extracted from 14 eligible articles. The genotypes of G1 and G4 polymorphisms were homozygous wild-type (WW), heterozygous (WM), and homozygous mutant-type (MM). The standardized mean difference (SMD) method using random effect models was employed to determine the effect size of G1 and G4 polymorphisms on LS under dominant, recessive, additive, and co-dominant genetic models...

OBJECTIVE: This study investigated the effectiveness of different physical forms of feed containing Ipomoea aquatica waste and concentrate feed on the rumen characteristics, chewing activity, and performance of sheep. MATERIALS AND METHODS: Twenty-four rams (19.87 ± 2.19 kg) were arranged in a completely randomized design. Rams were fed dried I. aquatica waste and concentrate feed provided separately (RCF) (conventional feeding system), and total mixed ration consisted of mash complete feed (MCF), and pelleted complete feed (PCF)...

INTRODUCTION: The COVID-19 can affects on human testicles, thus will interfere the production of important male sexual hormone such as testosterone. Our study provides scientific evidence through systematic reviews and meta-analyses that focus on the effects of SARSCoV- 2 virus infection on male sexual hormonal disorders in patients post-exposure to COVID-19. METHODS: This meta-analysis was made in accordance with the PRISMA guidelines. The outcomes of this study were the level of total testosterone, free testosterone, LH and FSH...

Indonesia is the largest archipelagic country in the world, with 70% of its territory covered by oceans that are rich in various types of biological resources. Indonesia's biodiversity has made it possible to develop natural medicine. Marine algae have enormous potential, but the types of marine algae used still need to be more varied. Research on the pharmacology of marine macroalgae has been conducted in Indonesia, but studies on such topic related to diabetes mellitus (DM) still need to be completed. This study provides a comprehensive dataset of pharmacological antidiabetic potential of marine macroalgae used for managing DM and reports on preclinical trials that provide pharmacological evidence...

Aim To determine the eff ect of hypoxic mesenchymal stem cells (MSCs) on the interleukin (IL)-10 and interferon (IFN)-gamma in peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients. Methods This study used a post-test control group design. Hypoxic MSCs were isolated and characterized according to their surface marker expression and diff erentiation capacities. PBMCs isolated from SLE patients were divided into three groups: control and two treatment groups. The treatment groups were treated by co-culturing MSCs to PBMCs with a ratio of 1:10 (T1) and 1:1 (T2) for 48 h incubation...

Huge amounts of noxious chemicals from coal and petrochemical refineries and pharmaceutical industries are released into water bodies. These chemicals are highly toxic and cause adverse effects on both aquatic and terrestrial life. The removal of hazardous contaminants from industrial effluents is expensive and environmentally driven. The majority of the technologies applied nowadays for the removal of phenols and other contaminants are based on physio-chemical processes such as solvent extraction, chemical precipitation, and adsorption...

Cilembu sweet potato is one of Indonesia's leading agricultural commodities. The high carbohydrate content in sweet potatoes has the potential to change into sugar (glucose, sucrose, and fructose) during storage. The level of sweetness is one of the characteristics that determines the quality of sweet potatoes. The sweetness level of sweet potatoes is influenced by various factors, including genetics, environment, and their interactions. Apart from that, the role of invertase-producing bacteria in breaking down carbohydrates into sugars is very important...

INTRODUCTION: Spina bifida occulta has a variety of symptoms that may hinder the diagnosis and subsequently delay appropriate treatment, causing a decrease in the patient's quality of life. This study aims to shed light on spina bifida occulta, with chronic low back pain as the predominant symptom, and the treatment applied in this case. PRESENTATION OF CASE: A 46-year-old male was diagnosed with spina bifida occulta at the 5th lumbar spine after 2 years of having chronic low back pain that radiated to the left leg...

BACKGROUND: The Maluku region encompasses thousands of islands. The study analyzed factors related to stunting among children under two years old in the Maluku Region of Indonesia. Study Design: A cross-sectional study. METHODS: This cross-sectional study examined 4764 children under two years. In addition to nutritional status (stature), the study analyzed ten independent variables (province, residence, maternal age, marital status, maternal education, employment, wealth, children's age, gender, and early initiation of breastfeeding [EIBF])...

Dengue virus infection (DVI) remains a significant health challenge, and diagnosis must still be considered. Non-structural protein 1 (NS1) is a potential marker of the dengue virus that can help diagnose DVI. The study aimed to assess the role of NS1 as a predictor of the severity of DVI. We utilized Dengue PCR-confirmed samples and employed semi-quantitative NS1Ag ELISA for NS1 examination, adhering to the World Health Organization South-East Asia Region (WHO-SEARO) 2011 criteria for DVI. We included DVI patients from Indonesia aged 1-65 years...

Membrane-based polyether sulfone (PES) is a potential candidate for hemodialysis because of its properties such as high mechanical strength, thermal stability, and chemical resistance. However, the nature of the hydrophobicity in the PES membrane inhibits their performance in transporting creatinine. In this study, polyethersulfone (PES) membranes were modified using a sulfonation process and modified with chitosan (CS) and lithium chloride (LiCl) to achieve a higher performance of the modified PES membrane for transporting creatinine compared to conventionally hemodialysis membrane...

In this study, ceramic materials of Mg(Ti0.99Sn0.01)O3 were synthesized and decorated on reduced graphene oxide, forming a nanocomposite of rGO/Mg(Ti0.99Sn0.01)O3 (rGO/MTS001). The successful synthesis results were confirmed by XRD, UV-Vis analysis, FT-IR, and SEM-EDS. The MTS001 has a flower-like morphology from SEM analysis, and the nanocomposites of rGO/MTS001 showed MTS001 particles decorated on rGO's surface. The electrochemical performance of rGO/MTS001 compared and MTS001 was investigated by determining the specific capacitance obtained in 1 M H2SO4 solution by cyclic voltammetry (CV), followed by galvanostatic charge-discharge (GCD) analysis using a three-electrode setup...

A 4πβ(PPC)-γ coincidence system has been made at KRISS based on a digital DAQ. 60 Co sources were measured to verify the system. The maximum detection efficiency for beta particles was estimated to be 96.7 %. Massic activities for sample sources had 0.005 % of the sample variability error, which was well within the expanded standard uncertainty of 0.54 % (k = 2).

BACKGROUND: Research has demonstrated that some tumor cells can transform into drug-tolerant persisters (DTPs), which serve as a reservoir for the recurrence of the disease. The persister state in cancer cells arises due to temporary molecular reprogramming, and exploring the genetic composition and microenvironment during the development of head and neck squamous cell carcinoma (HNSCC) can enhance our comprehension of the types of cell death that HNSCC, thus identifying potential targets for innovative therapies...