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https://www.readbyqxmd.com/read/29203099/effects-of-8-hydroxyisocapnolactone-2-3-diol-and-friedelin-on-mast-cell-degranulation
#1
Muhammad Novrizal Abdi Sahid, Agung Endro Nugroho, Ratna Asmah Susidarti, Kazutaka Maeyama
OBJECTIVE: To investigate the effects of friedelin (terpenoid) and 8-hydroxyisocapnolactone-2-3-diol (coumarin) with concentration 10 μM, 30 μM, and 100 μM on inhibiting mast cells (MCs) degranulation. METHODS: The investigation was performed in vitro by administering each compound into rat peritoneal MCs and rat basophilic leukemia-2H3 cells followed by activation with 50 μg/mL of compound 48/80 or 1 μM of ionomycin. The concentration of histamine released from each group was measured by a high-performance liquid chromatography-fluorometry system with post-column derivatization using o-phthalaldehyde...
November 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29101341/quantum-mechanics-as-classical-statistical-mechanics-with-an-ontic-extension-and-an-epistemic-restriction
#2
Agung Budiyono, Daniel Rohrlich
Where does quantum mechanics part ways with classical mechanics? How does quantum randomness differ fundamentally from classical randomness? We cannot fully explain how the theories differ until we can derive them within a single axiomatic framework, allowing an unambiguous account of how one theory is the limit of the other. Here we derive non-relativistic quantum mechanics and classical statistical mechanics within a common framework. The common axioms include conservation of average energy and conservation of probability current...
November 3, 2017: Nature Communications
https://www.readbyqxmd.com/read/29068106/clinical-profile-of-congenital-rubella-syndrome-in-yogyakarta-indonesia
#3
Elisabeth S Herini, Gunadi, Agung Triono, Fita Wirastuti, Kristy Iskandar, Niprida Mardin, Yati Soenarto
BACKGROUND: Congenital rubella syndrome (CRS) has many severe neurological manifestations and other systemic consequences in patients. Although various studies have been done in Indonesia, there have not been any conclusive results on CRS incidence. Therefore, we aimed to investigate the incidence, clinical manifestations and outcomes of CRS in Yogyakarta, Indonesia. METHODS: A descriptive study involving a review of congenital anomalies associated with CRS cases at Dr...
October 25, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28919828/jugular-bulb-oxygen-saturation-correlates-with-full-outline-of-responsiveness-score-in-severe-traumatic-brain-injury-patients
#4
Tjokorda Gde Agung Senapathi, Made Wiryana, Ketut Sinardja, Ketut Wibawa Nada, Ida Bagus Krisna Jaya Sutawan, Christopher Ryalino, Aloysius Alphonso
BACKGROUND: Maintaining brain oxygenation status is the main goal of treatment in severe traumatic brain injury (TBI). Jugular venous oxygen saturation (SjvO2) monitoring is a technique to estimate global balance between cerebral oxygen supply and its metabolic requirement. Full Outline of Responsiveness (FOUR) score, a new consciousness measurement scoring, is expected to become an alternative for Glasgow Coma Scale (GCS) in evaluating neurologic status of patients with severe traumatic head injury, especially for those under mechanical ventilation...
2017: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/28827562/transcriptional-control-of-motility-enables-directional-movement-of-escherichia-coli-in-a-signal-gradient
#5
Jayamary Divya Ravichandar, Adam G Bower, A Agung Julius, Cynthia H Collins
Manipulation of cellular motility using a target signal can facilitate the development of biosensors or microbe-powered biorobots. Here, we engineered signal-dependent motility in Escherichia coli via the transcriptional control of a key motility gene. Without manipulating chemotaxis, signal-dependent switching of motility, either on or off, led to population-level directional movement of cells up or down a signal gradient. We developed a mathematical model that captures the behaviour of the cells, enables identification of key parameters controlling system behaviour, and facilitates predictive-design of motility-based pattern formation...
August 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28761368/ultrasound-guided-bilateral-superficial-cervical-plexus-block-is-more-effective-than-landmark-technique-for-reducing-pain-from-thyroidectomy
#6
Tjokorda Gde Agung Senapathi, I Made Gede Widnyana, I Gusti Ngurah Mahaalit Aribawa, Made Wiryana, I Ketut Sinardja, I Ketut Wibawa Nada, Aa Gde Putra Semara Jaya, I Gede Koko Swadharma Putra
PURPOSE: Thyroidectomy causes postoperative pain and patient discomfort. Bilateral superficial cervical plexus block is a regional anesthesia technique that can provide analgesia during and after surgery. This study aims to compare the effectiveness of ultrasound (US)-guided versus landmark (LM) technique for bilateral superficial cervical plexus block in thyroidectomy. PATIENTS AND METHODS: Thirty-six patients undergoing thyroidectomy were divided into two groups randomly (n=18); either US-guided (US group) or LM technique (LM group) for bilateral superficial cervical plexus block...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28752803/designing-and-collecting-data-for-a-longitudinal-study-the-sleman-health-and-demographic-surveillance-system-hdss
#7
Fatwa S T Dewi, Ifta Choiriyyah, Citra Indriyani, Abdul Wahab, Lutfan Lazuardi, Agung Nugroho, Susetyowati Susetyowati, Rosalia K Harisaputra, Risalia Santi, Septi K Lestari, Nawi Ng, Mohammad Hakimi, Hari K Josef, Adi Utarini
BACKGROUND: This paper describes the methodological considerations of developing an urban Health and Demographic Surveillance System (HDSS), in the Sleman District of Yogyakarta, Indonesia. METHODS: 1) The Sleman District was selected because it is mostly an urban area. 2) The minimum sample size was calculated to measure infant mortality as the key variable and resulted in a sample of 4942 households. A two-stage cluster sampling procedure with probability proportionate to size was applied; first, 216 Censuses Blocks (CBs) were selected, and second, 25 households in each CB were selected...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28695925/anti-inflammatory-effects-of-an-ethanol-extract-of-aster-glehni-via-inhibition-of-nf-%C3%AE%C2%BAb-activation-in-mice-with-dss-induced-colitis
#8
Jun-Hyeok Choi, Kyung-Sook Chung, Bo-Ram Jin, Se-Yun Cheon, Agung Nugroho, Seong-Soo Roh, Hyo-Jin An
Although Aster glehni has been reported to prevent diabetes mellitus, hypercholesterolemia, insomnia, and cardiovascular disease, the anti-inflammatory effect of Aster glehni in colonic tissue remains unclear. In this study, we investigated the anti-inflammatory effects and the underlying molecular mechanism of an ethanol extract of Aster glehni (AG) in mice with dextran sulfate sodium (DSS)-induced colitis. AG significantly attenuated DSS-induced DAI scores, which implied that it suppressed diarrhea, gross bleeding, and the infiltration of immune cells...
July 19, 2017: Food & Function
https://www.readbyqxmd.com/read/28658964/products-of-chickpea-processing-as-texture-improvers-in-gluten-free-bread
#9
Libby G Bird, Casey L Pilkington, Agung Saputra, Luca Serventi
Recent market developments raised the need for alternatives to hydrocolloids as texture improver in gluten-free bread. Chickpea exerts several physicochemical properties (water- and oil-binding, emulsifying and foaming) that might address this need. Therefore, the effect of processing on chickpea functionality was tested on low ingredient dose, comparably to that of common hydrocolloids. Control bread was small, hard and with low gas retention ability as shown by microscopy, depicting holes inside crumb pores...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28645761/beach-macro-litter-monitoring-and-floating-microplastic-in-a-coastal-area-of-indonesia
#10
Agung Dhamar Syakti, Rafika Bouhroum, Nuning Vita Hidayati, Chandra Joei Koenawan, Abdelaziz Boulkamh, Isdy Sulistyo, Stephanie Lebarillier, Syafsir Akhlus, Pierre Doumenq, Pascal Wong-Wah-Chung
Qualitative analysis of the structures of the polymers composing floating plastic debris was performed using attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), and the aging of the debris was assessed by measuring carbonyl group formation on the particle surfaces. Plastic material made up >75% of the 2313 items collected during a three-year survey. The size, shape and color of the microplastic were correlated with the polymer structure. The most abundant plastic materials were polypropylene (68%) and low-density polyethylene (11%), and the predominant colors of the plastics were white, blue and green...
June 20, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28645725/cell-surface-n-glycan-alteration-in-hepad38-cell-lines-expressing-hepatitis-b-virus
#11
Surya Agung Priyambada, Ryo Misaki, Toru Okamoto, Yuta Okamoto, Takao Ohashi, Keiji Ueda, Yoshiharu Matsuura, Kazuhito Fujiyama
Hepatitis B virus (HBV) is the smallest partially double-stranded DNA virus known to infect humans. Worldwide, more than 50% of hepatocellular carcinoma (HCC) cases are related to chronic Hepatitis B. Development of HCC from normal liver cells is characterized by changes in cell surface N-glycans, which can promote the invasive behavior of tumor cells, leading ultimately to the progression of cancer. However, little is understood about the cell surface N-glycans of HBV-infected liver cells. We try to address this by taking advantage of the HepAD38 cell line, which can replicate HBV in the absence of tetracycline [tet(-)] in growth medium...
June 20, 2017: Virus Research
https://www.readbyqxmd.com/read/28634145/taeniasis-caused-by-taenia-saginata-in-gianyar-town-and-taenia-solium-in-karangasem-villages-of-bali-indonesia-2011-2016-how-to-detect-tapeworm-carriers-anamnesis-or-microscopy
#12
Kadek Swastika, Toni Wandra, Nyoman Sadra Dharmawan, I Made Sudarmaja, John Master Saragih, Luh Putu Eka Diarthini, Luh Ariwati, Putu Ayu Asri Damayanti, Dewa Ayu Agus Sri Laksemi, Nengah Kapti, Putu Sutisna, Tetsuya Yanagida, Akira Ito
From January 2011 until September 2016, screening of taeniasis carriers was carried out in a town in Gianyar District (Taenia saginata) and in villages which consisted of several Banjars (the smallest community units) on the eastern slope of Mt. Agung, Karangasem District (Taenia solium) in Bali, Indonesia. Fecal samples from all community members who chose to participate were examined microscopically for detection of taeniid eggs each person completedwith a questionnaire to determine if they had seen whitish, noodle-like proglottids (anamnesis) in their feces...
June 17, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28616952/room-temperature-discrete-charge-fluctuation-dynamics-of-a-single-molecule-adsorbed-on-a-carbon-nanotube
#13
Agung Setiadi, Hayato Fujii, Seiya Kasai, Ken-Ichi Yamashita, Takuji Ogawa, Takashi Ikuta, Yasushi Kanai, Kazuhiko Matsumoto, Yuji Kuwahara, Megumi Akai-Kasaya
Detection and use of physical noise fluctuations in a signal provides significant advantages in the development of bio- and neuro-sensing and functional mimicking devices. Low-dimensional carbon nanomaterials are a good candidate for use in noise generation due to the high surface sensitivity of these materials, which may themselves serve as the main building blocks of these devices. Here, we demonstrate that the addition of a molecule with high redox activity to a carbon nanotube (CNT) field-effect transistor provides tunable current fluctuation noise...
August 3, 2017: Nanoscale
https://www.readbyqxmd.com/read/28558246/buffers-strongly-modulate-fibrin-self-assembly-into-fibrous-networks
#14
Nicholas A Kurniawan, Thomas H S van Kempen, Stijn Sonneveld, Tilaï T Rosalina, Bart E Vos, Karin A Jansen, Gerrit W M Peters, Frans N van de Vosse, Gijsje H Koenderink
Fibrin is a plasma protein with a central role in blood clotting and wound repair. Upon vascular injury, fibrin forms resilient fibrillar networks (clots) via a multistep self-assembly process, from monomers, to double-stranded protofibrils, to a branched network of thick fibers. In vitro, fibrin self-assembly is sensitive to physicochemical conditions like the solution pH and ionic strength, which tune the strength of the noncovalent driving forces. Here we report a surprising finding that the buffer-which is necessary to control the pH and is typically considered to be inert-also significantly influences fibrin self-assembly...
June 27, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28550950/levels-and-sources-of-heavy-metals-and-pahs-in-sediment-of-djibouti-city-republic-of-djibouti
#15
Moussa Mahdi Ahmed, Pierre Doumenq, Mohamed Osman Awaleh, Agung Dhamar Syakti, Laurence Asia, Serge Chiron
Selected heavy metals and polycyclic aromatic hydrocarbons (PAHs) were determined in marine sediment from 28 sites Djibouti city. The concentrations of trace elements varied from 0 to 288.1mg/kg with relative abundance of trace metals in sediments was in the order of Zn>Cu>Ni>Cr>Co>Pb>Cd. Zn, Cu and Ni exceeded consensus based sediment quality guideline values 7, 14, 15 sites respectively. Enrichment factor and pollution load index showed relatively low to moderate contamination. The concentrations of total 16 PAHs varied widely depending on the sample location and ranged from 2...
May 24, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28529702/assessing-the-species-composition-of-tropical-eels-anguillidae-in-aceh-waters-indonesia-with-dna-barcoding-gene-cox1
#16
Zainal A Muchlisin, Agung Setia Batubara, Nur Fadli, Abdullah A Muhammadar, Afrita Ida Utami, Nurul Farhana, Mohd Nor Siti-Azizah
The objective of the present study was to evaluate the species diversity of eels native to Aceh waters based on genetic data. Sampling was conducted in western coast waters of Aceh Province, Indonesia, from July to August 2016. Genomic DNA was extracted from the samples, a genomic region from the 5' region of the cox1 gene was amplified and sequenced, and this was then used to analyse genetic variation. The genetic sequences were blasted into the NCBI database. Based on this analysis there were three valid species of eels that occurred in Aceh waters, namely Anguilla marmorata, A...
2017: F1000Research
https://www.readbyqxmd.com/read/28463979/gastric-mucosal-status-in-populations-with-a-low-prevalence-of-helicobacter-pylori-in-indonesia
#17
Muhammad Miftahussurur, Iswan Abbas Nusi, Fardah Akil, Ari Fahrial Syam, I Dewa Nyoman Wibawa, Yudith Annisa Ayu Rezkitha, Ummi Maimunah, Phawinee Subsomwong, Muhammad Luthfi Parewangi, I Ketut Mariadi, Pangestu Adi, Tomohisa Uchida, Herry Purbayu, Titong Sugihartono, Langgeng Agung Waskito, Hanik Badriyah Hidayati, Maria Inge Lusida, Yoshio Yamaoka
In Indonesia, endoscopy services are limited and studies about gastric mucosal status by using pepsinogens (PGs) are rare. We measured PG levels, and calculated the best cutoff and predictive values for discriminating gastric mucosal status among ethnic groups in Indonesia. We collected gastric biopsy specimens and sera from 233 patients with dyspepsia living in three Indonesian islands. When ≥5.5 U/mL was used as the best cutoff value of Helicobacter pylori antibody titer, 8.6% (20 of 233) were positive for H...
2017: PloS One
https://www.readbyqxmd.com/read/28435334/bispectral-index-value-correlates-with-glasgow-coma-scale-in-traumatic-brain-injury-patients
#18
Tjokorda Gde Agung Senapathi, Made Wiryana, I Gusti Ngurah Mahaalit Aribawa, Christopher Ryalino
BACKGROUND: Accuracy of consciousness level assessment is very important. It may determine and influence further clinical decisions, thus influences patients' outcomes. The widest method in determining the level of awareness is the Glasgow Coma Scale (GCS). Despite its common use, GCS scores obtained by one clinician may differ from others depending on their interpretations and past experience. One of the tools used to assess the level of consciousness objectively is bispectral index (BIS)...
2017: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/28252219/the-bandung-neurosurgery-patient-outcomes-project-indonesia-part-ii-patient-pathways-and-feasibility-and-acceptability-of-telephone-follow-up
#19
Agung Budi Sutiono, Ahmad Faried, Susan McAllister, Amelia Ganefianty, Kalih Sarjono, Muhammad Zafrullah Arifin, Sarah Derrett
INTRODUCTION: Support of neurosurgery patients following discharge from hospital is important. Currently, little is known about patients' in low- and middle-income countries before and after their hospital treatment. This companion paper reports patients' pathways before and after hospital admission and the feasibility of following up this ill-patient population by telephone. METHODS: Eligible patients were aged ≥18 years admitted to the Neurosurgery Department in Dr...
March 2, 2017: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/28252218/the-bandung-neurosurgery-patient-outcomes-project-indonesia-part-i-methods-participant-characteristics-and-pre-discharge-outcomes
#20
Susan McAllister, Amelia Ganefianty, Ahmad Faried, Agung Budi Sutiono, Kalih Sarjono, Regina Melia, Sheila Sumargo, Muhammad Zafrullah Arifin, Sarah Derrett
INTRODUCTION: Little is known about neurosurgery patient outcomes in Indonesia. Our study sought to describe patient characteristics, health care pathways, health-related quality of life, and health/rehabilitation care needs of patients admitted to, and discharged from, a major neurosurgery department. METHODS: Eligible patients were aged ≥18 years admitted to the Neurosurgery Department in a regional referral hospital in Bandung, Indonesia. Baseline data was collected on admission...
March 2, 2017: International Journal of Health Planning and Management
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