keyword
https://read.qxmd.com/read/38628349/early-pandemic-in-hospital-outcomes-and-mortality-risk-factors-in-covid-19-solid-organ-transplant-patients
#21
JOURNAL ARTICLE
Laith Alhuneafat, Muhammad Umar Khalid, Ahmad Jabri, Matthew D Deicke, Shiza Virk, Max W Jacobs, Eileen Hsich, Mohammad Alqarqaz, Mark E Dunlap, Hayah Kassis-George, Christopher Link
BACKGROUND: Solid organ transplant (SOT) recipients with COVID-19 have a higher risk of mortality than those without COVID-19. However, it is unclear how SOT patient outcomes compare to the general population without SOT who contract COVID-19. METHODS: We used the National Inpatient Sample from January to December 2020 to investigate inpatient outcomes seen in SOT recipients after contracting COVID-19 compared to nontransplant patients. We identified our study sample using ICD-10 CM and excluded those <18 years of age and those with dual organ transplants...
2024: Proceedings of the Baylor University Medical Center
https://read.qxmd.com/read/38617758/impact-of-atrial-fibrillation-on-1-year-outcome-in-patients-with-implantable-cardioverter-defibrillator-or-cardiac-resynchronization-therapy-with-defibrillator-results-from-the-german-device-registry
#22
JOURNAL ARTICLE
Sebastian Feickert, Niels Christian Ewertsen, Julia Köbe, Thomas Kleemann, Joachim Jehle, Jochen Senges, Matthias Hochadel, Dietrich Andresen, Christoph Stellbrink, Lars Eckardt, Stefan Spitzer, Johannes Brachmann, Hüseyin Ince, Giuseppe D'Ancona
BACKGROUND: Atrial fibrillation (AF) is a cardiac arrhythmia frequently documented in patients requiring implantable cardioverter defibrillators (ICDs) and/or cardiac resynchronization therapy with defibrillator (CRT-D). Patients with diagnosed AF at the point of ICD or CRT-D implantation may have an impaired follow-up outcome. METHODS: The German DEVICE I-II registry is a nationwide prospective multicentre database of patients implanted with ICD and CRT-D with clinical follow-up data...
March 29, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38605602/ecmo-for-drug-refractory-electrical-storm-without-a-reversible-trigger-a-retrospective-multicentric-observational-study
#23
JOURNAL ARTICLE
Isabel Durães-Campos, Catarina Costa, Ana Rita Ferreira, Carla Basílio, Pau Torrella, Aida Neves, Ana Margarida Lebreiro, Gonçalo Pestana, Luís Adão, José Pinheiro-Torres, Miguel Solla-Buceta, Jordi Riera, Juan Ignacio Chico-Carballas, Sérgio Gaião, José Artur Paiva, Roberto Roncon-Albuquerque
AIMS: Drug-refractory electrical storm (ES) is a life-threatening medical emergency. We describe the use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in drug-refractory ES without a reversible trigger, for which specific guideline recommendations are still lacking. METHODS AND RESULTS: Retrospective observational study in four Iberian centres on the indications, treatment, complications, and outcome of drug-refractory ES not associated with acute coronary syndromes, decompensated heart failure, drug toxicity, electrolyte disturbances, endocrine emergencies, concomitant acute illness with fever, or poor compliance with anti-arrhythmic drugs, requiring VA-ECMO for circulatory support...
April 11, 2024: ESC Heart Failure
https://read.qxmd.com/read/38591264/impact-of-a-chronic-total-coronary-occlusion-on-the-incidence-of-appropriate-implantable-cardioverter-defibrillator-shocks-and-mortality-a-substudy-of-the-dutch-outcome-in-icd-therapy-do-it-registry
#24
JOURNAL ARTICLE
Anna van Veelen, Tom E Verstraelen, Yvemarie B O Somsen, Joëlle Elias, Ivo M van Dongen, Peter Paul H M Delnoy, Marcoen F Scholten, Lucas V A Boersma, Alexander H Maass, Sipke Strikwerda, Mehran Firouzi, Cornelis P Allaart, Kevin Vernooy, Robert W Grauss, Raymond Tukkie, Paul Knaapen, Aeilko H Zwinderman, Marcel G W Dijkgraaf, Bimmer E P M Claessen, Marit van Barreveld, Arthur A M Wilde, José P S Henriques
BACKGROUND: Chronic total coronary occlusions (CTO) substantially increase the risk for sudden cardiac death. Among patients with chronic ischemic heart disease at risk for sudden cardiac death, an implantable cardioverter defibrillator (ICD) is the favored therapy for primary prevention of sudden cardiac death. This study sought to investigate the impact of CTOs on the risk for appropriate ICD shocks and mortality within a nationwide prospective cohort. METHODS AND RESULTS: This is a subanalysis of the nationwide Dutch-Outcome in ICD Therapy (DO-IT) registry of primary prevention ICD recipients in The Netherlands between September 2014 and June 2016 (n=1442)...
April 9, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38590268/electrical-storm-after-left-ventricular-assist-device-lvad-implantation
#25
JOURNAL ARTICLE
Suganya Karikalan, Min Choon Tan, Nan Zhang, Hicham El-Masry, Ammar M Killu, Christopher V DeSimone, Abhishek J Deshmukh, Christopher J McLeod, Dan Sorajja, Komandoor Srivathsan, Luis Scott, Yong-Mei Cha, Justin Z Lee
INTRODUCTION: Ventricular tachycardia storm or electrical storm (ES) is a common complication following left ventricular assist device (LVAD) implantation. The factors contributing to ES and outcomes are less studied. The study aimed to determine the factors associated with ES and the probability of survival in patients undergoing LVAD in three tertiary centers over a span of 15 years. METHODS: We performed a retrospective cohort study on all patients who underwent LVAD implantation at the Mayo Clinic (Rochester, Phoenix, and Jacksonville) from January 1, 2006 to December 31, 2020...
April 9, 2024: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/38588993/an-international-multicenter-cohort-study-on-implantable-cardioverter-defibrillators-for-the-treatment-of-symptomatic-children-with-catecholaminergic-polymorphic-ventricular-tachycardia
#26
JOURNAL ARTICLE
Avani Lamba, Thomas M Roston, Puck J Peltenburg, Dania Kallas, Sonia Franciosi, Krystien V V Lieve, Prince J Kannankeril, Minoru Horie, Seiko Ohno, Ramon Brugada, Takeshi Aiba, Peter Fischbach, Linda Knight, Jan Till, Sit-Yee Kwok, Vincent Probst, David Backhoff, Martin J LaPage, Anjan S Batra, Fabrizio Drago, Kristina Haugaa, Andrew D Krahn, Tomas Robyns, Heikki Swan, Terezia Tavacova, Joseph Atallah, Martin Borggrefe, Boris Rudic, Georgia Sarquella-Brugada, Ehud Chorin, Allison Hill, Janneke Kammeraad, Anna Kamp, Ian Law, James Perry, Jason D Roberts, Svjetlana Tisma-Dupanovic, Christopher Semsarian, Jonathan R Skinner, Jacob Tfelt-Hansen, Isabelle Denjoy, Antoine Leenhardt, Peter J Schwartz, Michael J Ackerman, Arthur A M Wilde, Christian van der Werf, Shubhayan Sanatani
BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia (CPVT) may cause sudden cardiac death (SCD) despite medical therapy. Therefore, implantable cardioverter defibrillators (ICDs) are commonly advised. However, there are limited data on the outcomes of ICD use in children. OBJECTIVE: To compare the risk of arrhythmic events in pediatric CPVT patients with and without ICDs. METHODS: We compared the risk of SCD in RYR2 variant and phenotype positive symptomatic CPVT patients with and without ICDs, who were <19 years of age and had no history of sudden cardiac arrest (SCA) at phenotype diagnosis...
April 6, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/38586835/isolation-of-the-superior-vena-cava-by-ultra-low-temperature-cryoablation
#27
JOURNAL ARTICLE
Khalid Bin Waleed, Zaki Akhtar, Lisa Wm Leung, Mark M Gallagher
A patient with shocks from his ICD related to AF underwent redo ablation. The only identifiable target was the superior vena cava. This was isolated using ultra-low cryotherapy, eliminating episodes of AF.
April 2024: Journal of Arrhythmia
https://read.qxmd.com/read/38584673/assessing-the-impact-of-omega-3-fatty-acids-on-ventricular-tachyarrhythmia-and-survival-in-patients-with-icds-a-systematic-review-and-meta-analysis
#28
REVIEW
Erfan Kohansal, Amir Askarinejad, MohammadHossein MozafaryBazargany, Amirreza Sabahizadeh, SeyedAbbas Pakmehr, Majid Haghjoo
BACKGROUND: Recent studies investigating the effects of fish oil on shocks administered by ICDs in patients with ventricular tachycardias produced inconclusive results. This systematic review aims to evaluate the effectiveness of omega-3 polyunsaturated fatty acids in lowering the risk of life-threatening VTs among individuals with implantable cardioverter-defibrillators. METHODS: We searched five databases, including Central, PubMed, EMBASE, Web of Science, and Scopus, for studies evaluating the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) for the prevention of ICD events for VT or VF, published up to December 1, 2023...
June 2024: IJC Heart & Vasculature
https://read.qxmd.com/read/38584394/impact-of-ventricular-tachycardia-ablation-in-subcutaneous-implantable-cardioverter-defibrillator-carriers-a-multicentre-international-analysis-from-the-isusi-project
#29
JOURNAL ARTICLE
Marco Schiavone, Alessio Gasperetti, Paolo Compagnucci, Julia Vogler, Mikael Laredo, Elisabetta Montemerlo, Simone Gulletta, Alexander Breitenstein, Matteo Ziacchi, Martin Martinek, Michela Casella, Pietro Palmisano, Lukas Kaiser, Carlo Lavalle, Leonardo Calò, Sebastian Seidl, Ardan M Saguner, Giovanni Rovaris, Jürgen Kuschyk, Mauro Biffi, Luigi Di Biase, Antonio Dello Russo, Claudio Tondo, Paolo Della Bella, Roland Tilz, Giovanni B Forleo
AIMS: Catheter ablation (CA) of ventricular tachycardia (VT) has become an important tool to improve clinical outcomes in patients with appropriate transvenous implantable cardioverter defibrillator (ICD) shocks. The aim of our analysis was to test whether VT ablation (VTA) impacts long-term clinical outcomes even in subcutaneous ICD (S-ICD) carriers. METHODS AND RESULTS: International Subcutaneous Implantable Cardioverter Defibrillator (iSUSI) registry patients who experienced either an ICD shock or a hospitalization for monomorphic VT were included in this analysis...
March 30, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38561134/nanoparticle-mediated-immunogenic-cell-death-for-cancer-immunotherapy
#30
REVIEW
Haolong Qi, Yuan Li, Yingjie Geng, Xinhuan Wan, Xiaoqing Cai
The field of cancer therapy is witnessing the emergence of immunotherapy, an innovative approach that activates the body own immune system to combat cancer. Immunogenic cell death (ICD) has emerged as a prominent research focus in the field of cancer immunotherapy, attracting significant attention in recent years. The activation of ICD can induce the release of damage-associated molecular patterns (DAMPs), such as calreticulin (CRT), adenosine triphosphate (ATP), high mobility group box protein 1 (HMGB1), and heat shock proteins (HSP)...
March 30, 2024: International Journal of Pharmaceutics
https://read.qxmd.com/read/38560436/sex-related-disparities-in-vehicle-crash-injury-and-hemodynamics
#31
JOURNAL ARTICLE
Susan Cronn, Karthik Somasundaram, Klaus Driesslein, Carissa W Tomas, Frank Pintar
OBJECTIVE: Multiple studies evaluate relative risk of female vs. male crash injury; clinical data may offer a more direct injury-specific evaluation of sex disparity in vehicle safety. This study sought to evaluate trauma injury patterns in a large trauma database to identify sex-related differences in crash injury victims. METHODS: Data on lap and shoulder belt wearing patients age 16 and up with abdominal and pelvic injuries from 2018 to 2021 were extracted from the National Trauma Data Bank for descriptive analysis using injuries, vital signs, International Classification of Disease (ICD) coding, age, and injury severity using AIS (Abbreviated Injury Scale) and ISS (Injury Severity Score)...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38558749/review-of-the-association-between-long-term-and-current-systemic-steroid-use-with-electromechanical-complications-and-inpatient-mortality-after-st-elevation-myocardial-infarction
#32
JOURNAL ARTICLE
Dennis D Kumi, Rohan Gajjar, Joshua T Narh, Edwin Gwira-Tamattey, Muhammad Sana, Nana Yaa Ampaw, Anna Oduro, Samuel M Odoi, Sheriff Dodoo, Setri Fugar
Background The impact of long-term systemic steroid use on electrical and mechanical complications following ST-segment elevation myocardial infarction (STEMI) has not been extensively studied. Methods In a retrospective cohort study of the National Inpatient Sample (NIS) from 2018 to 2020, adults admitted with STEMI were dichotomized based on the presence of long-term (current) systemic steroid (LTCSS) use. The primary outcome was all-cause mortality. Secondary outcomes included a composite of mechanical complications, electrical, hemodynamic, and thrombotic complications, as well as revascularization complexity, length of stay (LOS), and total charge...
February 2024: Curēus
https://read.qxmd.com/read/38556393/clinical-and-cardiac-mri-characteristics-prognosis-in-patients-with-alcoholic-cardiomyopathy
#33
JOURNAL ARTICLE
W Wang, S Li, B Zhuang, H Wang, Y Ren, L Xu
AIMS: Alcoholic cardiomyopathy (ACM) is recognized as a type of non-ischemic dilated cardiomyopathy (DCM). To date, the clinical prognosis of ACM remains a topic of debate in previous studies and there are limited studies on its cardiac MRI characteristics. The aim of this study was to summarize the clinical and MRI features of ACM patients and to identify the predictors of adverse prognosis based on clinical characteristics and MRI imaging findings. MATERIALS AND METHODS: Adult patients who were clinically diagnosed with ACM and underwent enhanced CMR between September 2015 and August 2022 were retrospectively enrolled...
March 13, 2024: Clinical Radiology
https://read.qxmd.com/read/38555535/intra-aortic-balloon-pump-is-associated-with-the-lowest-whereas-impella-with-the-highest-inpatient-mortality-and-complications-regardless-of-severity-or-hospital-types
#34
JOURNAL ARTICLE
Mohammad Reza Movahed, Armin Talle, Mehrtash Hashemzadeh
Impella and intra-aortic balloon pumps (IABP) are commonly utilized in patients with cardiogenic shock. However, the effect on mortality remains controversial. The goal of this study was to evaluate the effect of Impella and IABP on mortality in patients with cardiogenic shock the large Nationwide Inpatient Sample (NIS) database was utilized to study any association between the use of IABP or Impella on outcome. ICD-10 codes for Impella, IABP, and cardiogenic shock for available years 2016-2020 were utilized...
March 31, 2024: Cardiovascular Intervention and Therapeutics
https://read.qxmd.com/read/38538166/failure-to-terminate-ventricular-fibrillation-with-multiple-implantable-cardioverter-defibrillator-shocks-caused-by-shock-polarity
#35
JOURNAL ARTICLE
George Thomas, Jim W Cheung
No abstract text is available yet for this article.
March 2024: JACC. Clinical Electrophysiology
https://read.qxmd.com/read/38521121/implantable-cardioverter-defibrillators-for-primary-prevention-in-cardiomyopathies
#36
JOURNAL ARTICLE
Vineetha Kanneganti, Ajay Bahl, Manoj Kumar Rohit, Saurabh Mehrotra
BACKGROUND: Implantable cardioverter defibrillators (ICD) are often used as primary prevention strategy for sudden cardiac death (SCD) in young individuals. This study analyzed appropriate therapies, complications and inappropriate shocks in the real-world Indian population. METHODS: All patients in the cardiomyopathy cohort under follow up who had ICD implanted as a primary prevention strategy were studied. The objective was to assess the incidence of appropriate ICD therapies, inappropriate therapies and complications...
March 22, 2024: Indian Heart Journal
https://read.qxmd.com/read/38510954/trends-in-the-incidence-and-in-patient-outcomes-of-acute-myocardial-infarction-in-pregnancy-insights-from-the-national-inpatient-sample
#37
JOURNAL ARTICLE
Favour Markson, Rimaskep Garba Shamaki, Akanimo Antia, Anita Osabutey, Modele O Ogunniyi
STUDY OBJECTIVE: Pregnancy-related morbidity and mortality rates in the United States are rising despite advances in knowledge, technology, and healthcare delivery. Cardiovascular disease is the leading cause of adverse pregnancy outcomes, with acute myocardial infarction (AMI) being a potential contributor to the worse outcomes in pregnancy. DESIGN/SETTING: We analyzed data from the national inpatient sample database to examine trends in the incidence and in-hospital outcomes of myocardial infarction in pregnancy from 2016 to 2020...
October 2023: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38504757/electrical-storm-in-a-middle-aged-man
#38
Dzifa Ahadzi, Francis Agyekum, Alfred Doku, Abdul-Subulr Yakubu, Gwendolyn Hoedofia, Harold Ayetey
UNLABELLED: Electrical storm (ES) refers to a life-threatening condition characterised by three or more episodes of ventricular tachycardia (VT), ventricular fibrillation (VF), or appropriate implantable cardioverter defibrillator (ICD) shocks in 24 hours. We report a case of a 58-year-old man who suffered recurrent episodes of sustained VT despite appropriate defibrillation and antiarrhythmic drug therapy. On stepwise evaluation, arrhythmogenic right ventricular cardiomyopathy (ARVC) was considered the most likely substrate for his dysrhythmia...
June 2023: Ghana Medical Journal
https://read.qxmd.com/read/38495409/the-role-of-early-cardiac-resynchronization-therapy-implantation-in-dilated-cardiomyopathy-patients-with-narrow-qrs-carrying-lamin-a-c-mutation
#39
JOURNAL ARTICLE
Miry Blich, Wisam Darawsha, Allon Eyal, Faheem Shehadeh, Monther Boulous, Lior Gepstein, Mahmoud Suleiman
BACKGROUND: Dilated cardiomyopathy (DCM) caused by Lamin A/C gene (LMNA) mutation is complicated with atrioventricular conduction disturbances, malignant ventricular arrhythmias and progressive severe heart failure. OBJECTIVE: We hypothesized that early cardiac resynchronization therapy (CRT) implantation in LMNA mutation carriers with an established indication for pacemaker or implantable cardioverter defibrillator (ICD), may preserve ejection fraction, and delay disease progression to end stage heart failure...
2024: American Journal of Cardiovascular Disease
https://read.qxmd.com/read/38487587/surgical-ventricular-reconstruction-and-intraoperative-cryoablation-in-a-patient-with-drug-refractory-ventricular-tachycardia-and-left-ventricular-thrombus-a-case-report
#40
Maryuri Delgado Lopez, Julia Vogler, Anas Aboud, Christian-Hendrik Heeger, Roland Richard Tilz
BACKGROUND: Despite modern techniques for ablation of ventricular tachycardia (VT), the procedure faces challenges such as deep intramural substrates or inaccessibility of the pericardial space. We aim to present a case of successful surgical treatment of a patient with drug-refractory VT, an apical aneurysm, large left ventricular (LV) thrombus, and recurrent implantable cardioverter defibrillator (ICD) shocks following failed epicardial catheter ablation. CASE SUMMARY: A 67-year-old male with a history of ischaemic cardiomyopathy was brought to the emergency room after a syncope because of VT...
March 2024: European Heart Journal. Case Reports
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