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https://www.readbyqxmd.com/read/28730420/inappropriate-implantable-cardioverter-defibrillator-shocks-incidence-effect-and-implications-for-driver-licensing
#1
Eiichi Watanabe, Katsunori Okajima, Akira Shimane, Tomoya Ozawa, Tetsuyuki Manaka, Itsuro Morishima, Toru Asai, Masahiko Takagi, Toshihiro Honda, Atsunobu Kasai, Eitaro Fujii, Kohei Yamashiro, Ritsuko Kohno, Haruhiko Abe, Takashi Noda, Takashi Kurita, Shigeyuki Watanabe, Hiroya Ohmori, Takashi Nitta, Yoshifusa Aizawa, Ken Kiyono, Ken Okumura
PURPOSE: Patients with implantable cardioverter defibrillators (ICDs) have an ongoing risk of sudden incapacitation that may cause traffic accidents. However, there are limited data on the magnitude of this risk after inappropriate ICD therapies. We studied the rate of syncope associated with inappropriate ICD therapies to provide a scientific basis for formulating driving restrictions. METHODS: Inappropriate ICD therapy event data between 1997 and 2014 from 50 Japanese institutions were analyzed retrospectively...
July 20, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28718277/clinical-implications-of-long-term-ecg-monitoring-from-loop-recorder-to-devices-remote-control
#2
Andrea DI Cori, Raffaele DE Lucia
Long term ECG monitoring has become nowadays an indispensable technology for prevention, management and treatment of many cardiac issues. Today long term ECG monitoring is achievable through loop recorders (LR) and cardiac devices (CIED) like pacemaker (PM), implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy device-defibrillators (CRT- Ds), all of which associated with remote monitoring (RM). Targeted long term ECG monitoring Patients who have recurrent non documented episodes of palpitations, unexplained episodes of syncope, cryptogenic stroke or patients with a cardiomiopathy needing a risk stratification, may benefit from long term ECG monitoring...
July 18, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28716973/incremental-benefit-of-cardiac-resynchronisation-therapy-with-versus-without-a-defibrillator
#3
Pieter Martens, Frederik H Verbrugge, Petra Nijst, Matthias Dupont, Dieter Nuyens, Hugo Van Herendael, Maximo Rivero-Ayerza, Wilson H Tang, Wilfried Mullens
OBJECTIVE: To determine the incremental value of implantable cardioverter defibrillators (ICD) in contemporary optimally treated patients with heart failure (HF) undergoing cardiac resynchronisation therapy (CRT). METHODS: Consecutive patients with HF undergoing CRT-pacemaker (CRT-P) or CRT-defibrillator (CRT-D) implantation in a single tertiary care centre between October 2008 and August 2015 were retrospectively evaluated. For patients with a primary prevention indication of the CRT-D, no benefit of the ICD was defined as absence of appropriate therapy (device analysis) or lethal ventricular tachyarrhythmias (mode of death analysis) during follow-up...
July 17, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28705600/poor-medication-adherence-and-risk-of-relapse-associated-with-continued-cannabis-use-in-patients-with-first-episode-psychosis-a-prospective-analysis
#4
Tabea Schoeler, Natalia Petros, Marta Di Forti, Ewa Klamerus, Enrico Foglia, Robin Murray, Sagnik Bhattacharyya
BACKGROUND: Cannabis use following the onset of first-episode psychosis has been linked to both increased risk of relapse and non-adherence with antipsychotic medication. Whether poor outcome associated with cannabis use is mediated through an adverse effect of cannabis on medication adherence is unclear. METHODS: In a prospective analysis of data acquired from four different adult inpatient and outpatient units of the South London and Maudsley Mental Health National Health Service Foundation Trust in London, UK, 245 patients were followed up for 2 years from the onset of first-episode psychosis...
July 10, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28698789/a-population-based-study-on-myelodysplastic-syndromes-in-the-lazio-region-italy-medical-miscoding-and-11-year-mortality-follow-up-the-gruppo-romano-laziale-mielodisplasie-experience-of-retrospective-multicentric-registry
#5
Flavia Mayer, Laura Faglioni, Nera Agabiti, Susanna Fenu, Francesco Buccisano, Roberto Latagliata, Roberto Ricci, Maria Antonietta Aloe Spiriti, Caterina Tatarelli, Massimo Breccia, Giuseppe Cimino, Luana Fianchi, Marianna Criscuolo, Svitlana Gumenyuk, Stefano Mancini, Luca Maurillo, Carolina Nobile, Pasquale Niscola, Anna Lina Piccioni, Agostino Tafuri, Giulio Trapè, Alessandro Andriani, Paolo De Fabritiis, Maria Teresa Voso, Marina Davoli, Gina Zini
Data on Myelodysplastic Syndromes (MDS) are difficult to collect by cancer registries because of the lack of reporting and the use of different classifications of the disease. In the Lazio Region, data from patients with a confirmed diagnosis of MDS, treated by a hematology center, have been collected since 2002 by the Gruppo Romano-Laziale Mielodisplasie (GROM-L) registry, the second MDS registry existing in Italy. This study aimed at evaluating MDS medical miscoding during hospitalizations, and patients' survival...
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/28686818/antipsychotic-medication-treatment-patterns-in-adult-depression
#6
Tobias Gerhard, T Scott Stroup, Christoph U Correll, Cecilia Huang, Zhiqiang Tan, Stephen Crystal, Mark Olfson
OBJECTIVE: To characterize the role of antipsychotic medications in the community treatment of adult depression. METHODS: We identified adults (aged 18-64 years) with new episodes of depression treatment (ICD-9-CM 296.2, 296.3, 300.4, or 311) in US national Medicaid data (2001-2010). Patients with alternative ICD-9-CM antipsychotic indications, such as schizophrenia or bipolar disorder, were excluded. Each patient was followed for at least 1 year to characterize antipsychotic and antidepressant treatment and emerging alternative antipsychotic indications...
July 5, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28680620/ranolazine-safe-and-effective-in-a-patient-with-hypertensive-cardiomyopathy-and-multiple-episodes-of-electrical-storm
#7
Panagiotis Margos, Nikolaos Margos, Nadiya Mokadem, Ilias Patsiotis, Athanasios Kranidis
Among implantable cardioverter-defibrillator (ICD) recipients, there are patients with recurrent episodes of electrical storm (ES), retractable to the optimal antiarrhythmic drug therapy or invasive ablation procedures. A relatively novel anti-ischemic drug with also antiarrhythmic properties, ranolazine, may effectively suppress ventricular arrhythmias in such patients for a long period of time.
July 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28664342/effect-of-supplemented-intake-of-omega-3-fatty-acids-on-arrhythmias-in-patients-with-icd-fish-oil-therapy-may-reduce-ventricular-arrhythmia
#8
Dalit Weisman, Roy Beinart, Aharon Erez, Nira Koren-Morag, Ilan Goldenberg, Michael Eldar, Michael Glikson, David Luria
PURPOSE: The aim of this study was to evaluate the effects of fish oils, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on ventricular tachyarrhythmic episodes (VTEs) in implantable cardioverter defibrillator (ICD) recipients with ischemic cardiomyopathy. METHODS: One hundred five ICD recipients with ischemic cardiomyopathy received 3.6 g of EPA and DHA and placebo for 6 months, each at a random order, with a 4-month washout period between treatments...
June 29, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28663067/economic-burden-of-diverticular-disease-an-observational-analysis-based-on-real-world-data-from-an-italian-region
#9
F S Mennini, P Sciattella, A Marcellusi, B Toraldo, M Koch
INTRODUCTION: Diverticular disease (DD), a herniation of the colonic mucosa through the muscle layer, covers a wide variety of conditions associated with the presence of diverticula in the colon. The most serious form is an acute episode of diverticulitis, which can lead to hospitalization and surgery with various types of consequences. The main aim of this study is to evaluate the economic burden of hospitalizations arising from acute episodes of diverticulitis using data from the administrative databases used in the Marche region in Italy and, as a secondary objective of this real-world data analysis, to study patient outcome variables following initial hospitalization for diverticulitis...
June 8, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28658116/an-interesting-implantable-cardioverter-defibrillator-treatment-for-lethal-ventricular-arrhythmias-caused-by-coronary-artery-spasm-a-case-report
#10
Jie Sun, Li Feng, Fei Li, Yanchun Zhang, Jianting Dong
RATIONALE: Coronary artery spasm (CAS) could cause serious lethal ventricular arrhythmias. While implantable cardioverter defibrillators (ICDs) have been recommend for secondary prevention of sudden cardiac death related to lethal ventricular arrhythmias. However, in resuscitated sudden cardiac death caused by CAS, the effect of ICD is still not well clear. PATIENT CONCERNS: A 60-year-old male presented with 2 episodes of syncope. Coronary angiography showed normal coronary arteries...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28650247/burden-of-alcohol-abuse-or-dependence-among-long-term-opioid-users-with-chronic-noncancer-pain
#11
Pamela B Landsman-Blumberg, Nathaniel Katz, Kavita Gajria, Anna D Coutinho, Paul P Yeung, Richard White
BACKGROUND: Substance abuse disorders among chronic noncancer pain (CNCP) patients add to the clinical challenges and economic burden of caring for such patients. Despite potential risks, some CNCP patients with a history of alcohol abuse or dependence (AAD) and pain that is refractory to nonopioid treatment options may still need opioids for pain management. However, there is a lack of data on adverse outcomes in long-term opioid users with CNCP and a history of substance abuse or AAD disorders...
July 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28648856/presentations-for-hypoglycemia-associated-with-diabetes-mellitus-to-emergency-departments-in-a-canadian-province-a-database-and-epidemiological-analysis
#12
Chris J Alexiu, Anderson Chuck, Susan E Jelinski, Brian H Rowe
AIMS: The prevalence of diabetes mellitus was reportedly 9% in 2014, making it one of the most common global chronic conditions. Hypoglycemia is an important complication of diabetes treatment. The objective of this study was to quantify and characterize hypoglycemia presentations associated with type 1 or 2 diabetes made to emergency departments (EDs) by adults in a Canadian province. METHODS: A retrospective cohort study was conducted using reliable administrative data from Alberta for a five-year period (2010/11-2014/15)...
March 11, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28636575/the-temperament-and-character-traits-in-patients-with-major-depressive-disorder-and-bipolar-affective-disorder-with-and-without-suicide-attempt
#13
Anamarija Petek Erić, Ivan Erić, Mario Ćurković, Katarina Dodig-Ćurković, Kristina Kralik, Vlatka Kovač, Pavo Filaković
BACKGROUND: Suicide and mood disorders (especially major depressive disorder (MDD) and bipolar affective disorder (BD)) represent a significant global health burden. Major depressive disorder and bipolar affective disorder have been associated with increased risk for suicide. Some specific suicide risk factors might be found in underlying individual personality traits. Specific personality features may predispose an individual to mood disorders (MDD or BD) hence increased suicide risk...
June 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28636092/impact-of-diagnosis-of-von-willebrand-disease-on-patient-outcomes-analysis-of-medical-insurance-claims-data
#14
R F Sidonio, K M Haley, D Fallaize
The inherited bleeding disorder von Willebrand disease (VWD) is challenging to diagnose owing to disease heterogeneity, lack of a definitive laboratory test and variations in diagnostic criteria. We evaluated the impact of diagnosis and diagnostic delay on patient outcomes. The PharMetrics Plus Database was interrogated for medical claims for VWD (ICD-9 286.4) and bleeding events between 1 January 2006 and 30 June 2015. Longitudinal analysis was performed of patients newly diagnosed with VWD (≥9 months' continuous enrolment before first VWD claim) through 24 months following diagnosis...
June 21, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28633049/physical-activity-correlates-among-24-230-people-with-depression-across-46-low-and-middle-income-countries
#15
Davy Vancampfort, Brendon Stubbs, Joseph Firth, Mats Hallgren, Felipe Schuch, Jouni Lahti, Simon Rosenbaum, Philip B Ward, James Mugisha, André F Carvalho, Ai Koyanagi
BACKGROUND: There is a paucity of nationally representative data available on the correlates of physical activity (PA) among people with depression, especially in low- and middle-income countries (LMICs). Thus, we investigated PA correlates among community-dwelling adults with depression in this setting. METHODS: World Health Survey data included 24,230 adults (43.1 ± 16.1 years; 36.1% male) with ICD-10 diagnoses of depression including brief depressive episode and subsyndromal depression aged ≥ 18 years from 46 LMICs...
October 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28631695/-chronic-stress-and-mental-disorders-in-patients-with-systemic-scleroderma-results-of-an-interdisciplinary-study
#16
O F Seravina, T A Lisitsyna, M N Starovoytova, O V Desinova, O B Kovalevskaya, D Yu Veltishchev
AIM: To analyze of the prevalence of stressful factors and mental disorders (MDs), as well as their clinical psychopathological and clinical psychological characteristics to improve the comprehensive diagnosis and treatment of systemic scleroderma (SSD). SUBJECTS AND METHODS: Examinations were performed in 110 patients (predominantly women (n=97 (88.2%); mean age, 49.9±2.47 years) with a documented diagnosis of SSD (its mean duration, 7.25±0.42 years). 62 (56...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28625728/treatment-of-persistent-ventricular-tachycardia-drugs-or-ablation
#17
REVIEW
Ciorsti J MacIntyre, John L Sapp
Implantable cardioverter defibrillators (ICDs) reduce the mortality risk associated with recurrent ventricular tachycardia (VT) and can frequently terminate VT episodes painlessly, but do not prevent recurrent episodes. For patients with symptomatic recurrences, frequent asymptomatic recurrences, ICD shocks, or VT storm, most clinicians recommend strategies to suppress VT. The proarrhythmic mortality risk of antiarrhythmic drugs (AADs) may be mitigated by the presence of an ICD, but these medications are limited by high recurrence rates, and unfavorable side effect profiles...
May 10, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28607617/influence-of-myopotential-interference-on-the-wavelet-discrimination-algorithm-in-implantable-cardioverter-defibrillator
#18
Kazuya Mizukami, Hisashi Yokoshiki, Hirofumi Mitsuyama, Masaya Watanabe, Taro Tenma, Rui Kamada, Masayuki Takahashi, Ryo Sasaki, Motoki Maeno, Hiroyuki Tsutsui
BACKGROUND: Wavelet is a morphology-based algorithm for detecting ventricular tachycardia. The electrogram (EGM) source of the Wavelet algorithm is nominally programmed with the Can-RV coil configuration, which records a far-field ventricular potential. Therefore, it may be influenced by myopotential interference. METHODS: We performed a retrospective review of 40 outpatients who had an implantable cardioverter-defibrillator (ICD) with the Wavelet algorithm. The percent-match score of the Wavelet algorithm was measured during the isometric chest press by pressing the palms together...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28606693/etiological-diagnosis-prognostic-significance-and-role-of-electrophysiological-study-in-patients-with-brugada-ecg-and-syncope
#19
Carla Giustetto, Natascia Cerrato, Enrico Ruffino, Elena Gribaudo, Chiara Scrocco, Lorella Barbonaglia, Francesca Bianchi, Miriam Bortnik, Guido Rossetti, Paula Carvalho, Riccardo Riccardi, Davide Castagno, Matteo Anselmino, Laura Bergamasco, Fiorenzo Gaita
BACKGROUND: Syncope is considered a risk factor for life-threatening arrhythmias in Brugada patients. Distinguishing a benign syncope from one due to ventricular arrhythmias is often difficult, unless an ECG is recorded during the episode. Aim of the study was to analyze the characteristics of syncopal episodes in a large population of Brugada patients and evaluate the role of electrophysiological study (EPS) and the prognosis in the different subgroups. METHODS AND RESULTS: One hundred ninety-five Brugada patients with history of syncope were considered...
August 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28606073/associations-between-patient-factors-and-adverse-events-in-the-home-care-setting-a-secondary-data-analysis-of-two-canadian-adverse-event-studies
#20
Nancy A Sears, Régis Blais, Michael Spinks, Michèle Paré, G Ross Baker
BACKGROUND: Early identification of patients at who have a higher risk for the occurrence of harm can provide patient safety improvement opportunities. Patient factors contribute to adverse event occurrence. The study aim was to identify a single, parsimonious model of home care patient factors that, regardless of location and differences in home care program management and design factors, could provide a means of locating patients at higher and lower risk of harm. METHODS: Split modeling using secondary analyses of data from two recent Canadian home care patient safety studies was undertaken...
June 12, 2017: BMC Health Services Research
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