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https://www.readbyqxmd.com/read/29678782/early-feasibility-of-hypoglossal-nerve-upper-airway-stimulator-in-patients-with-cardiac-implantable-electronic-devices-and-continuous-positive-airway-pressure-intolerant-severe-obstructive-sleep-apnea
#1
Valay Parikh, Erica Thaler, Masanari Kato, M Boyd Gillespie, Shaun Nguyen, Kirk Withrow, David Calhoun, Ryan Soose, Damien Stevens, Suzanne Stevens, Chris Larsen, Madhu Reddy, Dhanunjaya Lakkireddy
BACKGROUND: Implantable hypoglossal nerve upper airway stimulation (HNS) is a novel, FDA approved strategy for management of moderate to severe obstructive sleep apnea(OSA) patients with continuous positive airway pressure (CPAP) therapy intolerance or failure. Due to proximity of Cardiac Implantable Electronic Devices (CIED) and this stimulator, interaction between these devices is theoretically possible. OBJECTIVE: The purpose of this study was to assess interactions between implantable hypoglossal nerve upper airway stimulator device and cardiac implantable electronic devices...
April 17, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29626346/propofol-for-implantable-cardioverter-defibrillator-implantation-in-patients-with-brugada-syndrome
#2
Hye-Mee Kw On, Sung-Hoon Kim, Se-Ung Pa Rk, Jin-Ho Rh Im, Hee-Su N Park, Wook-Jong Kim, Gi-Byou Ng Nam
AIMS: Avoiding propofol in patients with Brugada syndrome has been suggested because of the theoretical risk of provoking ventricular arrhythmias, although propofol may be selected for conscious sedation during electrophysiological procedures in catheterization laboratories. This study aimed to document peri-procedural electrocardiographic changes and adverse events in patients with Brugada syndrome undergoing implantable cardioverter defibrillator (ICD) implantation using propofol sedation...
April 6, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29605187/antipsychotic-drugs-versus-cognitive-behavioural-therapy-versus-a-combination-of-both-in-people-with-psychosis-a-randomised-controlled-pilot-and-feasibility-study
#3
Anthony P Morrison, Heather Law, Lucy Carter, Rachel Sellers, Richard Emsley, Melissa Pyle, Paul French, David Shiers, Alison R Yung, Elizabeth K Murphy, Natasha Holden, Ann Steele, Samantha E Bowe, Jasper Palmier-Claus, Victoria Brooks, Rory Byrne, Linda Davies, Peter M Haddad
BACKGROUND: Little evidence is available for head-to-head comparisons of psychosocial interventions and pharmacological interventions in psychosis. We aimed to establish whether a randomised controlled trial of cognitive behavioural therapy (CBT) versus antipsychotic drugs versus a combination of both would be feasible in people with psychosis. METHODS: We did a single-site, single-blind pilot randomised controlled trial in people with psychosis who used services in National Health Service trusts across Greater Manchester, UK...
March 28, 2018: Lancet Psychiatry
https://www.readbyqxmd.com/read/29603492/demand-for-neurological-services-in-central-eastern-europe-a-10-year-national-survey-in-hungary
#4
Ferenc Oberfrank, András Ajtay, Dániel Bereczki
BACKGROUND: To plan neurological capacities at a national level for the next decade the current use of neurological services should be evaluated. We analyze the utilization of neurological services in Hungary, a country with a single-payer health insurance system covering the whole population. METHODS: We created a database from medical reports submitted to the National Health Insurance Fund from all hospitals and outpatient services between 2004 and 2013. The number of subjects presenting in the neurological healthcare system, and their major diagnoses by ICD-10 categories are analyzed...
March 30, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29590416/opportunistic-screening-for-alcohol-use-problems-in-adolescents-attending-emergency-departments-an-evaluation-of-screening-tools
#5
Simon Coulton, M Fasihul Alam, Sadie Boniface, Paolo Deluca, Kim Donoghue, Eilish Gilvarry, Eileen Kaner, Ellen Lynch, Ian Maconochie, Paul McArdle, Ruth McGovern, Dorothy Newbury-Birch, Robert Patton, Ceri J Phillips, Thomas Phillips, Hannah Rose, Ian Russell, John Strang, Colin Drummond
Objective: To estimate and compare the optimal cut-off score of Alcohol Use Disorders Identification Test (AUDIT) and AUDIT-C in identifying at-risk alcohol consumption, heavy episodic alcohol use, ICD-10 alcohol abuse and alcohol dependence in adolescents attending ED in England. Design: Opportunistic cross-sectional survey. Setting: 10 emergency departments across England. Participants: Adolescents (n = 5377) aged between their 10th and 18th birthday who attended emergency departments between December 2012 and May 2013...
March 26, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29588140/cochlear-implant-function-in-a-patient-with-jervell-and-lange-nielsen-syndrome-after-defibrillation-by-countershock
#6
Shinsuke Kaneshiro, Harukazu Hiraumi, Kirito Shimamoto, Kaori Sasamori, Yumiko Kobayashi, Hiroaki Sato
Jervell and Lange-Nielsen syndrome (JLNS), a rare autosomal recessive congenital QT prolongation syndrome, is characterized by cardiac arrhythmias, syncopal episodes, and profound deafness. A cochlear implant (CI) for patients with JLNS is expected to result in hearing improvement. Sometimes, defibrillation is required if a patient experiences lethal arrhythmia. In this paper, we report a pediatric patient with JLNS who received defibrillation after CI surgery in his right ear at the age of 2 years. With intensive care, the post-operative course was uneventful, and the patient acquired satisfactory speech and hearing abilities...
March 24, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29580450/opioid-utilization-by-pregnant-women-with-sickle-cell-disease-and-the-risk-of-neonatal-abstinence-syndrome
#7
Aisha Nnoli, Neil S Seligman, Kevin Dysart, Jason K Baxter, Samir K Ballas
BACKGROUND: Pregnant women with sickle cell disease (SCD) are at increased risk of maternal and fetal complications. There are limited data on the outcome of the treatment of VOCs with opioids in relation to neonatal complications during pregnancy. METHODS: This is a retrospective cohort study of women with SCD from January 1999 to December 2008. Women with SCD were identified by ICD-9 codes and matched 2:1 to a control group of women on methadone for opioid dependence...
April 2018: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29579109/using-data-linkage-to-electronic-patient-records-to-assess-the-validity-of-selected-mental-health-diagnoses-in-english-hospital-episode-statistics-hes
#8
Katrina Alice Southworth Davis, Oliver Bashford, Amelia Jewell, Hitesh Shetty, Robert J Stewart, Cathie L M Sudlow, Matthew Hugo Hotopf
BACKGROUND: Administrative data can be used to support research, such as in the UK Biobank. Hospital Episode Statistics (HES) are national data for England that include contain ICD-10 diagnoses for inpatient mental healthcare episodes, but the validity of these diagnoses for research purposes has not been assessed. METHODS: 250 peoples' HES records were selected based on a HES recorded inpatient stay at the South London and Maudsley NHS Foundation Trust with a diagnosis of schizophrenia, a wider schizophrenia spectrum disorder, bipolar affective disorder or unipolar depression...
2018: PloS One
https://www.readbyqxmd.com/read/29557531/beta-blocker-therapy-is-associated-with-a-lower-incidence-of-syncope-due-to-fast-ventricular-tachycardias-among-implantable-cardioverter-defibrillator-patients-with-left-ventricular-dysfunction-results-from-a-multicenter-study
#9
Javier Jiménez-Candil, Ignasi Anguera, Olga Durán, Jesús Hernández, Javier Fernández-Portales, José Luis Moríñigo, Ana Martín, Paolo Dallaglio, Loreto Bravo, Andrea di Marco, Pedro Luis Sánchez
INTRODUCTION: Among implantable cardioverter-defibrillator (ICD) patients, a substantial proportion of syncopes are due to fast ventricular tachycardias (FVTs). In the experimental models of ventricular tachycardias, the arterial vasoconstriction plays an important role in recovering the arterial pressure. Since beta-blockers increase vascular resistance, we hypothesized that beta-blockers could reduce the occurrence of syncope due to FVTs. Our objective was to determine the relationship between the beta-blocker therapy and the incidence of syncope in FVT (cycle length [CL] 250-320 ms) occurring in ICD patients...
March 20, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29524750/determinants-of-access-to-health-care-for-depression-in-49-countries-a-multilevel-analysis
#10
Ricardo Araya, Pedro Zitko, Niina Markkula, Dheeraj Rai, Kelvyn Jones
BACKGROUND: The relative importance of individual and country-level factors influencing access to diagnosis and treatment for depression across the world is fairly unknown. METHODS: We analysed cross-national data from the WHO World Health Surveys. Depression diagnosis and access to health care were ascertained using a structured interview. Logistic Bayesian Multilevel analyses were performed to establish individual and country level factors associated with: (1) receiving a diagnosis and (2) accessing treatment for depression if a diagnosis was ascertained...
February 27, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29523431/electroconvulsive-therapy-and-risk-of-dementia-in-patients-with-affective-disorders-a-cohort-study
#11
Merete Osler, Maarten Pieter Rozing, Gunhild Tidemann Christensen, Per Kragh Andersen, Martin Balslev Jørgensen
BACKGROUND: Electroconvulsive therapy (ECT) is the most effective treatment for severe episodes of mood disorders. Temporary memory loss is a common side-effect, but ongoing discussions exist regarding potential long-term adverse cognitive outcomes. Only a few studies have examined the frequency of dementia in patients after ECT. The aim of this study was to examine the association between ECT and risk of subsequent dementia in patients with a first-time hospital diagnosis of affective disorder...
March 6, 2018: Lancet Psychiatry
https://www.readbyqxmd.com/read/29520510/variant-angina-and-aborted-sudden-cardiac-death
#12
REVIEW
Amartya Kundu, Aditya Vaze, Partha Sardar, Ahmed Nagy, Wilbert S Aronow, Naomi F Botkin
PURPOSE OF REVIEW: Variant angina, which is characterized by recurrent chest pain and transient ECG changes along with angiographic evidence of coronary artery spasm, generally has a favorable prognosis. However, episodes of ischemia caused by vasospasm may lead to potentially life-threatening ventricular arrhythmias and cardiac arrest, even in patients with no history of prior cardiac disease. This review describes the epidemiology, pathogenesis, clinical spectrum, and management of variant angina, as well as outcomes in patients who present with aborted sudden cardiac death (ASCD)...
March 8, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29506756/defining-the-pattern-of-initiation-of-monomorphic-ventricular-tachycardia-using-the-beat-to-beat-intervals-recorded-on-implantable-cardioverter-defibrillators-from-the-raft-study-a-computer-based-algorithm
#13
Rodrigo S Barbosa, Leon Glass, Riccardo Proietti, Barry Burstein, Ahmed Al-Turki, Lyndon Sobolik, Zhubo Zhang, Guillaume Viart, Michelle Samuel, Alvin Shrier, Vidal Essebag
Arrhythmia onset pattern may have important implications on morbidity, recurrent implantable cardioverter defibrillator (ICD) shocks, and mortality, given the proposed correlation between initiation pattern and arrhythmia mechanism. Therefore, we developed and tested a computer-based algorithm to differentiate the pattern of initiation based on the beat-to-beat intervals of the ventricular tachycardia (VT) episodes in ICD recordings from the Resynchronization-Defibrillation for Ambulatory Heart Failure Trial (RAFT)...
February 3, 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29482533/indicators-for-early-assessment-of-palliative-care-in-lung-cancer-patients-a-population-study-using-linked-health-data
#14
Maria Kelly, Katie M O'Brien, Michael Lucey, Kerri Clough-Gorr, Ailish Hannigan
BACKGROUND: Analysing linked, routinely collected data may be useful to identify characteristics of patients with suspected lung cancer who could benefit from early assessment for palliative care. The aim of this study was to compare characteristics of newly diagnosed lung cancer patients dying within 30 days of diagnosis (short term survivors) with those surviving more than 30 days. To identify indicators for early palliative care assessment we distinguished between characteristics available at diagnosis (age, gender, smoking status, marital status, comorbid disease, admission type, tumour stage and histology) from those available post diagnosis...
February 26, 2018: BMC Palliative Care
https://www.readbyqxmd.com/read/29479646/prior-fragility-fracture-and-risk-of-incident-ischaemic-cardiovascular-events-results-from-uk-biobank
#15
J Paccou, S D'Angelo, A Rhodes, E M Curtis, Z Raisi-Estabragh, M Edwards, K Walker-Bone, C Cooper, S E Petersen, N C Harvey
In the large UK Biobank population-based cohort, we found that amongst men, but not women, prior fragility fracture was associated with increased risk of admission with ischaemic heart disease. INTRODUCTION: We aimed to investigate the relationship between prior fracture and risk of incident ischaemic cardiovascular events in a UK population-based cohort. METHODS: UK Biobank is a large prospective cohort comprising 502,637 men and women aged 40-69 years, with detailed baseline assessment...
February 26, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29479013/renal-denervation-for-ventricular-arrhythmia-in-patients-with-implantable-cardioverter-defibrillators
#16
Zhixin Jiang, Xiujuan Zhou, Chun Chen, Ying Wang, Ping Fang, Jie Geng, Gang Zhang, Qijun Shan
To investigate the efficacy of renal denervation (RDN) on the recurrence of ventricular arrhythmia (VA) in Asian patients with implantable cardioverter defibrillators (ICDs).Eight ICD patients with recurrent VA episodes underwent RDN using an off-the-shelf saline-irrigated catheter. The pre- and postprocedural VA episodes were counted via ICD interrogation. All patients underwent successful RDN without any complications related to radiofrequency catheter ablation. The median follow-up was 15 months (range 6-30), and the median VA episodes per month were significantly reduced from 3...
February 23, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29478022/physical-activity-measured-by-implanted-devices-predicts-atrial-arrhythmias-and-patient-outcome-results-of-implanted-italian-multicentre-observational-registry-on-patients-with-implantable-devices-remotely-monitored
#17
Pietro Palmisano, Federico Guerra, Ernesto Ammendola, Matteo Ziacchi, Ennio Carmine Luigi Pisanò, Gabriele Dell'Era, Vittorio Aspromonte, Maria Zaccaria, Francesco Di Ubaldo, Alessandro Capucci, Gerardo Nigro, Eraldo Occhetta, Giampiero Maglia, Renato Pietro Ricci, Giuseppe Boriani, Michele Accogli
BACKGROUND: To determine whether daily physical activity (PA), as measured by implanted devices (through accelerometer sensor), was related to the risk of developing atrial arrhythmias during long-term follow-up in a population of heart failure (HF) patients with an implantable cardioverter defibrillator (ICD). METHODS AND RESULTS: The study population was divided into 2 equally sized groups (PA cutoff point: 3.5 h/d) according to their mean daily PA recorded by the device during the 30- to 60-day period post-ICD implantation...
February 24, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29462281/linking-hospital-patient-records-for-suspected-or-established-acute-coronary-syndrome-in-a-complex-secondary-care-system-a-proof-of-concept-e-registry-in-nhs-scotland
#18
Iain Findlay, Tamsin Morris, Ruiqi Zhang, Colin McCowan, Sarah Shield, Brian Forbes, Alex McConnachie, Kenneth Mangion, Colin Berry
Aims: To implement secondary care electronic record linkage for patients hospitalised with suspected or known acute coronary syndrome (ACS) in a complex regional healthcare system and evaluate this e-Registry in terms of patterns of service delivery and 1-year outcomes. Methods and Results: Existing electronic hospital records were linked to create episodes of care using (1) a patient administration system, (2) invasive cardiovascular procedure referrals and (3) a catheter laboratory record...
February 16, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29451517/-burden-of-diverticular-disease-an-observational-analysis-based-on-italian-real-world-data
#19
Francesco Saverio Mennini, Paolo Sciattella, Andrea Marcellusi, Bernardo Toraldo, Maurizio Koch
INTRODUCTION: Diverticular disease (DD) represent a wide variety of conditions associated with the presence of diverticula in the colon. The most serious form is an acute episode of diverticulitis which can lead to hospitalization and surgery with various types of consequences. The main aim of this study was to evaluate, from both cross-sectional and longitudinal perspective, the economic burden of diverticulitis in the real practice. METHOD: A deterministic linkage was performed at individual user level between the different administrative sources of the Marche Region through anonymised ID number for a period of analysis between 1 January 2008 and 31 December 2014...
January 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29451406/cancer-costs-and-outcomes-for-common-cancer-sites-in-the-finnish-population-between-2009-2014
#20
Paulus Torkki, Riikka-Leena Leskelä, Miika Linna, Suvi Mäklin, Jukka-Pekka Mecklin, Petri Bono, Vesa Kataja, Sakari Karjalainen
BACKGROUND: The cost of cancer and outcomes of cancer care have been discussed a lot since cancer represents 3-6% of total healthcare costs and cost estimations have indicated growing costs. There are studies considering the cost of all cancers, but studies focusing on the cost of disease and outcomes in most common cancer sites are limited. The objective of this study was to analyze the development of the costs and outcomes in Finland between 2009 and 2014 per cancer site. METHODS: The National cost, episode and outcomes data were obtained from the National register databases based on International Statistical Classification of Diseases (ICD)-10 diagnosis codes...
February 16, 2018: Acta Oncologica
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