keyword
MENU ▼
Read by QxMD icon Read
search

Personality disorder drug treatment

keyword
https://www.readbyqxmd.com/read/28087060/personality-in-parkinson-s-disease-clinical-behavioural-and-cognitive-correlates
#1
REVIEW
Gabriella Santangelo, Fausta Piscopo, Paolo Barone, Carmine Vitale
Affective disorders and personality changes have long been considered pre-motor aspects of Parkinson's disease (PD). Many authors have used the term "premorbid personality" to define distinctive features of PD patients' personality characterized by reduced exploration of new environmental stimuli or potential reward sources ("novelty seeking") and avoidance behaviour ("harm avoidance") present before motor features. The functional correlates underlying the personality changes described in PD, implicate dysfunction of meso-cortico-limbic and striatal circuits...
January 5, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28049461/mental-distress-following-inpatient-substance-use-treatment-modified-by-substance-use-comparing-voluntary-and-compulsory-admissions
#2
Adrian R Pasareanu, John-Kåre Vederhus, Anne Opsal, Øistein Kristensen, Thomas Clausen
BACKGROUND: Treatment services to patients with substance use disorders (SUDs), including those mandated to treatment, needs to be evaluated and evidence based. The Norwegian Municipal Health Care Act (NMHCA) calls for compulsory treatment for persons with "severe and life-threatening substance use disorder" if these individuals are not otherwise willing to be voluntarily treated and consequently risk their lives over drug use. Mental distress is known to be high among SUD patients admitted to inpatient treatment...
January 3, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28028732/interactive-voice-response-with-feedback-intervention-in-outpatient-treatment-of-substance-use-problems-in-adolescents-and-young-adults-a-randomized-controlled-trial
#3
Claes Andersson, Agneta Öjehagen, Martin O Olsson, Louise Brådvik, Anders Håkansson
PURPOSE: Substance use disorders and problematic substance use are common problems in adolescence and young adulthood. Brief personalized feedback has been suggested for treatment of alcohol and drug problems and poor mental health. This repeated measurement randomized controlled trial examines the effect of an interactive voice response (IVR) system for assessing stress, depression, anxiety and substance use. METHODS: The IVR system was used twice weekly over 3 months after treatment initiation, with or without addition of a personalized feedback intervention on stress and mental health symptoms...
December 27, 2016: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28028587/safety-of-zidovudine-lamivudine-scored-tablets-in-children-with-hiv-infection-in-europe-and-thailand
#4
Ali Judd
BACKGROUND: Zidovudine (ZDV) has been associated with risk of haematological toxicity. Safety data from clinical trials is generally limited to 48 weeks. We assessed the short- and mid-term toxicity of ZDV/lamivudine (3TC) fixed-dose combination scored tablets in HIV-infected children followed in the European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) network. METHODS: Fourteen cohorts provided data on patients <18 years of age taking ZDV/3TC scored tablets between 2008 and 2012...
December 27, 2016: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28027792/-clinical-practice-guidelines-irritable-bowel-syndrome-with-constipation-and-functional-constipation-in-adults-concept-diagnosis-and-healthcare-continuity-part-1-of-2
#5
F Mearin, C Ciriza, M Mínguez, E Rey, J J Mascort, E Peña, P Cañones, J Júdez
In this Clinical practice guide, an analysis is made of the diagnosis and treatment of adult patients with constipation and abdominal discomfort, under the spectrum of irritable bowel syndrome and functional constipation. These have an important personal, health and social impact, affecting the quality of life of these patients. In irritable bowel syndrome with a predominance of constipation, this is the predominant change in bowel movements, with recurrent abdominal pain, bloating and frequent abdominal distension...
December 24, 2016: Atencion Primaria
https://www.readbyqxmd.com/read/28025939/serotonin-selective-reuptake-inhibitors-ssris-and-female-sexual-dysfunction-fsd-hypothesis-on-its-association-and-options-of-treatment
#6
Nurul Azmi Mahamad Rappek, Hatta Sidi, Jaya Kumar, Sazlina Kamarazaman, Srijit Das, Ruziana Masiran, Najwa Baharudin, Muhammad Hatta
Sexual dysfunctions are commonly seen in women on selective serotonin reuptake inhibitors (SSRIs). The complexities of female sexual functioning are reflected through modulation of inter-playing factors like the neuropsychophysiological factors, inter-personal and relationship issue, psychiatric co-morbidities and physical disorder. The incidence of SSRIs-induced FSD is difficult to estimate because of the potentially confounding effects of SSRIs, presence of polypharmacy, marital effect, socio-cultural factors and due to the design and assessment problems in majority of the studies...
December 27, 2016: Current Drug Targets
https://www.readbyqxmd.com/read/28017183/quitting-smoking-during-substance-use-disorders-treatment-patient-and-treatment-related-variables
#7
Barbara K Campbell, Thao Le, Barbara Tajima, Joseph Guydish
Although individuals in substance use disorders (SUD) treatment continue to smoke at high rates, regulatory, policy and programming changes promoting tobacco cessation are being implemented and some patients quit successfully. We examined associations of smoking patterns, tobacco advertising receptivity, anti-tobacco message awareness, health risk perception, attitudes towards addressing smoking and availability of smoking cessation services with quitting smoking during SUD treatment. Surveys were completed by 1127 patients in 24 programs chosen randomly, stratified by program type (residential, methadone maintenance, outpatient), from among publicly funded, adult treatment programs within the National Drug Abuse Treatment Clinical Trials Network...
February 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/27988332/suicide-attempts-and-markers-of-immune-response-in-individuals-with-serious-mental-illness
#8
Faith Dickerson, Holly C Wilcox, Maria Adamos, Emily Katsafanas, Sunil Khushalani, Andrea Origoni, Christina Savage, Lucy Schweinfurth, Cassie Stallings, Kevin Sweeney, Robert Yolken
Previous studies have identified elevations in antibodies to Toxoplasma gondii in individuals with a history of suicide attempts but studies have not measured the association between suicide attempts and a panel of antibody markers. We assessed 162 patients receiving treatment for schizophrenia, bipolar disorder, or major depression on the Columbia Suicide Severity Rating Scale for suicide attempt history and other clinical measures. All participants had a blood sample drawn from which were measured antibodies to Toxoplasma gondii and other neurotropic infectious agents...
December 1, 2016: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27979428/demographic-trends-of-binge-alcohol-use-and-alcohol-use-disorders-among-older-adults-in-the-united-states-2005-2014
#9
Benjamin H Han, Alison A Moore, Scott Sherman, Katherine M Keyes, Joseph J Palamar
BACKGROUND: Alcohol use is common among older adults, and this population has unique risks with alcohol consumption in even lower amounts than younger persons. No recent studies have estimated trends in alcohol use including binge alcohol use and alcohol use disorders (AUD) among older adults. METHODS: We examined alcohol use among adults age ≥50 in the National Survey on Drug Use and Health (NSDUH) from 2005 to 2014. Trends of self-reported past-month binge alcohol use and AUD were estimated...
January 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27978805/alzheimer-s-disease-a-review-from-the-pathophysiology-to-diagnosis-new-perspectives-for-pharmacological-treatment
#10
Leide Caroline Dos Santos Picanço, Priscilla Farias Ozela, Maiara de Fátima de Brito Brito, Abraão Alves Pinheiro, Elias Carvalho Padilha, Francinaldo Sarges Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues Dos Santos, Joaquín María Campos Rosa, Lorane Izabel da Silva Hage-Melim
Dementia is characterized by the impairment of cognition and behavior of people over 65 years. Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in the world, as approximately 47 million people are affected by this disease and the tendency is that this number will increased 62% by 2030. Two microscopic features assist in the characterization of the disease, the amyloid plaques and neurofibrillary agglomerates. All these factors are responsible for the slow and gradual deterioration of memory that affect language, personality or cognitive control...
December 12, 2016: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/27960654/a-case-of-dose-escalation-of-quetiapine-in-persistent-insomnia-disorder
#11
Claudia Cornelis, Ann Van Gastel, Glenn Dumont, Violette Coppens, Bernard Sabbe, Manuel Morrens, Filip Van Den Eede
Quetiapine, an atypical antipsychotic drug, is recommended for the treatment of schizophrenia and mood disorders. In addition, given its sedative effects, a low dose of the agent is also widely used in the treatment of anxiety disorders, personality disorders, substance abuse, and sleep disturbances. In this case study, quetiapine was the first effective drug in reducing chronic insomnia in a male patient with a long treatment history. Because its effect declined over time, in the course of two years, a gradual dose increase led to a posology 50 times higher than the off-label dosage used to obtain sedation, i...
December 14, 2016: Acta Clinica Belgica
https://www.readbyqxmd.com/read/27930499/prevalence-and-risk-factors-of-prolonged-corrected-qt-interval-among-children-and-adolescents-treated-with-antipsychotic-medications-a-long-term-follow-up-in-a-real-world-population
#12
Inmaculada Palanca-Maresca, Belén Ruiz-Antorán, Gustavo Adolfo Centeno-Soto, Maria Azul Forti-Buratti, Ana Siles, Ana Usano, Cristina Avendaño-Solá
PURPOSE: This study aimed to describe the prevalence of corrected QT (QTc) interval disorders and the possible predisposing factors in children and adolescents treated with antipsychotic (AP) medications in a real-world population with a long-term follow-up. METHODS: Data were obtained from the SafEty of NeurolepTics in Infancy and Adolescence (SENTIA) registry (https://sentia.es). The SENTIA includes patients younger than 18 years who are currently taking or initiating treatment with AP medications and have agreed to participate in the registry...
February 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/27903845/protein-biomarkers-of-mood-disorders
#13
EDITORIAL
Carmen Rodríguez Cerdeira, Elena Sánchez-Blanco, Beatriz Sánchez-Blanco, Jose Luis González-Cespón
Psychiatric evaluation presents a significant challenge because it conceptually integrates the input from multiple psychopathological approaches. Recent technological advances in the study of protein structure, function, and interactions have provided a breakthrough in the diagnosis and treatment of mood disorders (MD), and have identified novel biomarkers to be used as indicators of normal and disease states or response to drug treatment. The investigation of biomarkers for psychiatric disorders, such as enzymes (catechol-O-methyl transferase and monoamine oxidases) or neurotransmitters (dopamine, serotonin, norepinephrine) and their receptors, particularly their involvement in neuroendocrine activity, brain structure, and function, and response to psychotropic drugs, should facilitate the diagnosis of MD...
November 30, 2016: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/27889704/pharmacogenetic-studies-a-tool-to-improve-antidepressant-therapy
#14
Marta Ramos, Cecilia Berrogain, Julia Concha, Laura Lomba, Cristina Belén García, Mª Pilar Ribate
The World Health Organization (WHO) predicts that major depressive disorder (MDD) will be the second leading cause of death and disability by 2020. Nowadays, approximately 60-70% of patients with this disorder have shown the lack of effectiveness and tolerability of the therapy with antidepressants. The US Food and Drug Administration (FDA) and the European Medicine Agency (EMA) are including pharmacogenetic information in the labeling of several antidepressants. The presence of this information represents the relevance of genetic polymorphisms in drug response...
December 1, 2016: Drug Metabolism and Personalized Therapy
https://www.readbyqxmd.com/read/27884974/from-leeches-to-personalized-medicine-evolving-concepts-in-the-management-of-polycythemia-vera
#15
REVIEW
Alessandro M Vannucchi
Polycythemia vera is a clonal disorder of hematopoietic stem/progenitor cells. It manifests as an expansion of red cell mass. It is the most common chronic myeloproliferative neoplasm. In virtually all cases, it is characterized by a V617F point mutation in JAK2 exon 14 or less common mutations in exon 12. The landmark discovery of the autonomously activated JAK/STAT signaling pathway paved the way for the clinical development of the first target drug, the JAK1 and JAK2 inhibitor ruxolitinib. This is now approved for patients with resistance or intolerance to hydroxyurea...
January 2017: Haematologica
https://www.readbyqxmd.com/read/27882090/clinical-treatment-of-malignant-hyperthermia-in-three-cases
#16
Tao Pan, Wenli Ji, Mengqi Nie, Yang Li
Malignant hyperthermia (MH) is a rare life threatening inherited disorder that is triggered by drugs used for general anesthesia in susceptible persons. The symptoms include rapid increase of body temperature and severe muscle contractions. The present study includes 3 cases of MH and highlights the timely identification of symptoms for rescuing the patient. In case I, a 7-year-old male child underwent surgery with ketamine at a dose of 250 mg. After 4 h of operation, the child went through convulsions, high fever and succumbed within a few hours...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27878322/assessing-needs-for-psychiatric-treatment-in-prisoners-1-prevalence-of-disorder
#17
Paul Bebbington, Sharon Jakobowitz, Nigel McKenzie, Helen Killaspy, Rachel Iveson, Gary Duffield, Mark Kerr
BACKGROUND: High levels of psychiatric morbidity in prisoners have important implications for services. Assessing Needs for Psychiatric Treatment in Prisoners is an evaluation of representative samples of prisoners in a male and a female prison in London. This paper reports on the prevalence of mental disorders. In a companion paper, we describe how this translates into mental health treatment needs and the extent to which they have been met. METHODS: Prisoners were randomly sampled in a sequential procedure based on the Local Inmate Data System...
November 22, 2016: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/27871720/-guidelines-for-the-prescription-of-mood-stabilizers-for-adolescents-a-literature-review
#18
G Munch, N Godart
INTRODUCTION: Adolescence is a unique phase of the human developmental process. In adolescents, psychotropic medications may have different efficacy and tolerance profiles compared to those at other stages of the lifespan. Mood stabilizers are a complex pharmacological category including lithium, some anticonvulsants, and some second generation antipsychotics. Focusing on this class of pharmacological agents, we aim to answer the following questions: in which indications and according to which modalities should mood stabilizers be prescribed during adolescence? METHODS: Information was sought from the websites of the French Haute Autorité de santé (HAS) and Agence nationale de sécurité du médicament et des produits de santé (ANSM), the American Food and Drug Administration (FDA) and the British National Institute for Health and Clinical Excellence (NICE)...
November 18, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27856209/qualitative-evaluation-of-perceptions-of-smoking-cessation-among-clients-at-an-alcohol-and-other-drug-treatment-program
#19
Jennifer Bhuiyan, Lauren Jonkman, Sharon Connor, Vincent Giannetti
BACKGROUND: Smoking is highly prevalent in the substance use population and trials of smoking cessation among patients actively receiving treatment for substance use disorder have yielded modest quit rates. However, smoking cessation is not routinely provided due to the ungrounded belief it will interfere with recovery from the primary substance use problem. OBJECTIVES: The objective of this qualitative study was to determine the perceptions of smoking cessation in a substance use population...
November 3, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27849405/psychiatric-symptoms-parental-attachment-and-reasons-for-use-as-correlates-of-heavy-substance-use-among-treatment-seeking-hispanic-adolescents
#20
Karina A Gattamorta, Alberto Varela, Brian E McCabe, Maite P Mena, Daniel A Santisteban
: In early adolescence, Hispanics self-report higher drug use rates compared to White and African American peers. Among adolescent users, heavy users have more negative behavioral and health consequences. The purpose of this cross-sectional study is to examine whether psychiatric symptoms, parental attachment, and reasons for use predict heavy alcohol and illicit drug use (more than 10 times in the past three months) among Hispanic adolescents. METHODS: This study examines baseline data from a study evaluating a family based substance abuse treatment program for Hispanic adolescents...
November 16, 2016: Substance Use & Misuse
keyword
keyword
12033
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"