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Preterm infant outcomes

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https://www.readbyqxmd.com/read/29222398/cerebral-palsy-in-extremely-preterm-infants
#1
Maria Hafström, Karin Källén, Fredrik Serenius, Karel Maršál, Eva Rehn, Helen Drake, Ulrika Ådén, Aijaz Farooqi, Kristina Thorngren-Jerneck, Bo Strömberg
BACKGROUND AND OBJECTIVES: The risk of cerebral palsy (CP) is high in preterm infants and is often accompanied by additional neurodevelopmental comorbidities. The present study describes lifetime prevalence of CP in a population-based prospective cohort of children born extremely preterm, including the type and severity of CP and other comorbidities (ie, developmental delay and/or cognitive impairment, neurobehavioral morbidity, epilepsy, vision and hearing impairments), and overall severity of disability...
December 8, 2017: Pediatrics
https://www.readbyqxmd.com/read/29217722/successfully-implementing-and-embedding-guidelines-to-improve-the-nutrition-and-growth-of-preterm-infants-in-neonatal-intensive-care-a-prospective-interventional-study
#2
Mark J Johnson, Alison A Leaf, Freya Pearson, Howard W Clark, Borislav D Dimitrov, Catherine Pope, Carl R May
OBJECTIVES: We aimed to improve the nutritional care of preterm infants by developing a complex (multifaceted) intervention intended to translate current evidence into practice. We used the sociological framework of Normalization Process Theory (NPT), to guide implementation in order to embed the new practices into routine care. DESIGN: A prospective interventional study with a before and after methodology. PARTICIPANTS: Infants <30 weeks gestation or <1500 g at birth...
December 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/29215314/prenatal-perceived-stress-and-adverse-birth-outcomes-among-puerto-rican-women
#3
Kathleen Szegda, Elizabeth R Bertone-Johnson, Penelope Pekow, Sally Powers, Glenn Markenson, Nancy Dole, Lisa Chasan-Taber
BACKGROUND: Preterm birth and low birthweight contribute substantially to the disproportionately high infant mortality rates experienced by Puerto Ricans in the United States. The purpose of this study was to examine whether the timing and pattern of prenatal psychosocial stress increased risk of adverse birth outcomes in this high-risk population. MATERIALS AND METHODS: Proyecto Buena Salud was a prospective cohort study conducted from 2006 to 2011 among predominantly Puerto Rican women...
December 7, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29212432/maternity-leave-duration-and-adverse-pregnancy-outcomes-an-international-country-level-comparison
#4
Emma Kwegyir-Afful, George Adu, Evelien R Spelten, Kimmo Räsänen, Jos Verbeek
AIM: Preterm birth and low birthweight (LBW) lead to infant morbidity and mortality. The causes are unknown. This study evaluates the association between duration of maternity leave and birth outcomes at country level. METHOD: We compiled data on duration of maternity leave for 180 countries of which 36 specified prenatal leave, 190 specified income, 183 specified preterm birth rates and 185 specified the LBW rate. Multivariate and seemingly unrelated regression analyses were done in STATA...
December 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29211493/department-of-defense-birth-and-infant-health-registry-select-reproductive-health-outcomes-2003-2014
#5
Anna T Bukowinski, Ava Marie S Conlin, Gia R Gumbs, Zeina G Khodr, Richard N Chang, Dennis J Faix
Established following a 1998 directive, the Department of Defense Birth and Infant Health Registry (Registry) team conducts surveillance of select reproductive health outcomes among military families. Data are compiled from the Military Health System Data Repository and Defense Manpower Data Center to define the Registry cohort and outcomes of interest. Outcomes are defined using ICD-9/ICD-10 and Current Procedural Terminology codes, and include: pregnancy outcomes (e.g., live births, losses), birth defects, preterm births, and male:female infant sex ratio...
November 2017: MSMR
https://www.readbyqxmd.com/read/29210994/iron-supplementation-during-pregnancy-and-infancy-uncertainties-and-implications-for-research-and-policy
#6
REVIEW
Patsy M Brannon, Christine L Taylor
Iron is particularly important in pregnancy and infancy to meet the high demands for hematopoiesis, growth and development. Much attention has been given to conditions of iron deficiency (ID) and iron deficient anemia (IDA) because of the high global prevalence estimated in these vulnerable life stages. Emerging and preliminary evidence demonstrates, however, a U-shaped risk at both low and high iron status for birth and infant adverse health outcomes including growth, preterm birth, gestational diabetes, gastrointestinal health, and neurodegenerative diseases during aging...
December 6, 2017: Nutrients
https://www.readbyqxmd.com/read/29209031/racial-differences-in-neonatal-hypoglycemia-among-very-early-preterm-births
#7
Tamarra James-Todd, Melissa I March, Jacqueline Seiglie, Munish Gupta, Florence M Brown, Joseph A Majzoub
OBJECTIVE: To determine whether the prevalence of neonatal hypoglycemia differs by race/ethnicity. STUDY DESIGN: A retrospective cohort study using prospectively collected data from 515 neonates born very preterm (<32 weeks) to normoglycemic women and admitted to the neonatal intensive care unit (NICU) at a major tertiary hospital in Boston, MA, between 2008 and 2012. RESULTS: A total of 61%, 12%, 7%, 7%, and 13% were White, Black, Hispanic, Asian, and Other, respectively...
December 5, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29208241/increased-trophoblast-inclusions-in-placentas-from-prematurely-born-infants-a-potential-marker-of-risk-for-preterm-neurodevelopmental-outcomes
#8
Morgan R Firestein, Rosanna Abellar, Michael M Myers, Martha G Welch
Trophoblast inclusions (TIs) are placental abnormalities of the trophoblast bilayer. Present in 2-8% of full-term placentas, they are associated with poor neurodevelopment, including autism. Although previously unstudied, examination of chorionic villi from 108 preterm births revealed a ∼4 fold increase in the frequency of TIs (30.5%). Frequency of TIs was inversely related to gestational age (GA); 43% of placentas <30 weeks and 20% of placentas ≥32 weeks had TIs (χ2 = 4.41, p = 0.036). This increased prevalence in preterm infants suggests that TIs may indicate adverse intrauterine processes or undetected genetic abnormalities and could identify infants at risk for poor neurodevelopment...
December 2017: Placenta
https://www.readbyqxmd.com/read/29207214/feed-thickener-for-infants-up-to-six-months-of-age-with-gastro-oesophageal-reflux
#9
REVIEW
T'ng Chang Kwok, Shalini Ojha, Jon Dorling
BACKGROUND: Gastro-oesophageal reflux (GOR) is common in infants, and feed thickeners are often used to manage it in infants as they are simple to use and perceived to be harmless. However, conflicting evidence exists to support the use of feed thickeners. OBJECTIVES: To evaluate the use of feed thickeners in infants up to six months of age with GOR in terms of reduction in a) signs and symptoms of GOR, b) reflux episodes on pH probe monitoring or intraluminal impedance or a combination of both, or c) histological evidence of oesophagitis...
December 5, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29205635/cerebral-white-matter-maturation-patterns-in-preterm-infants-an-mri-t2-relaxation-anisotropy-and-diffusion-tensor-imaging-study
#10
Michael J Knight, Adam Smith-Collins, Sarah Newell, Mark Denbow, Risto A Kauppinen
BACKGROUND AND PURPOSE: Preterm birth is associated with worse neurodevelopmental outcome, but brain maturation in preterm infants is poorly characterized with standard methods. We evaluated white matter (WM) of infant brains at term-equivalent age, as a function of gestational age at birth, using multimodal magnetic resonance imaging (MRI). METHODS: Infants born very preterm (<32 weeks gestation) and late preterm (33-36 weeks gestation) were scanned at 3 T at term-equivalent age using diffusion tensor imaging (DTI) and T2 relaxometry...
December 5, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29205630/health-care-professionals-approach-in-feeding-term-small-for-gestational-age-infants-and-its-potential-implications-to-later-growth-outcomes
#11
Le Ye Lee, Leilani Muhardi, Fook-Choe Cheah, Sarayut Supapannachart, Inga C Teller, Jacques Bindels, Eline M van Der Beek, Ruurd M van Elburg
AIM: To understand feeding practices, nutrition management and postnatal growth monitoring of term small-for-gestational age (tSGA) infants in Southeast Asia. METHODS: Anonymous questionnaires to assess practices on feeding, nutrition management and post-natal growth monitoring of tSGA infants were distributed among health-care professionals (HCPs) participating in regional/local perinatology symposia in Malaysia, Thailand and Singapore. RESULTS: Three hundred seventy-seven respondents from Malaysia (37%), Thailand (27%), Singapore (18%) and other Asian countries (19%) participated in the survey...
December 5, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29202729/changes-in-prevalence-and-perinatal-outcomes-of-congenital-hydrocephalus-among-chinese-newborns-a-retrospective-analysis-based-on-the-hospital-based-birth-defects-surveillance-system
#12
Ling Yi, Chaomin Wan, Changfei Deng, Xiaohong Li, Kui Deng, Yi Mu, Jun Zhu, Qi Li, Yanping Wang, Li Dai
BACKGROUND: Little is known about the epidemiology of congenital hydrocephalus (CH) in China. This study aimed to depict recent changes in CH prevalence and perinatal outcomes of the affected newborns. METHODS: Data were obtained from the Chinese Birth Defects Monitoring Network (CBDMN), which collects demographic information on all newborns above 28 weeks of gestation, and clinical information on neonates with congenital anomalies. CH cases delivered during 2005-2012 were analyzed...
December 4, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29201824/assessment-of-preterm-infants-using-the-bayley-iii-scales-in-korea
#13
Sung Ho Ahn, Soo A Kim
Objective: To assess the well-being of preterm newborns using the Bayley-III scales in a Korean-based population, and to evaluate the perinatal risk factors influencing developmental outcome. Methods: Using the Bayley-III scales, we assessed 120 preterm infants who were referred for evaluation of neurodevelopmental performance. We subdivided them into an extremely preterm group (n=18) and a very/moderate to late preterm group (n=102). Bayley-III mean scores and the rate of infants showing a delay were compared for both groups...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29200180/procedural-pain-and-oral-glucose-in-preterm-neonates-brain-development-and-sex-specific-effects
#14
Juliane Schneider, Emma G Duerden, Ting Guo, Karin Ng, Patric Hagmann, Myriam Bickle Graz, Ruth E Grunau, M Mallar Chakravarty, Petra S Hüppi, Anita C Truttmann, Steven P Miller
Our objectives were to determine whether procedural pain and glucose exposure are associated with altered structural and functional brain development differently in preterm males and females, and neurodevelopment at 18-months corrected age. Fifty-one very-preterm neonates (22 males; median[IQR] gestational age 27.6[2.0] weeks) underwent three serial scans including T1-weighted and resting-state functional magnetic resonance imaging (MRI) at median postmenstrual weeks: 29.4, 31.9, and 41.1. Thalamus, basal ganglia, and total brain volumes were segmented...
December 1, 2017: Pain
https://www.readbyqxmd.com/read/29199029/the-effect-of-customization-and-use-of-a-fetal-growth-standard-on-the-association-between-birthweight-percentile%C3%A2-and-adverse-perinatal-outcome
#15
Ulla Sovio, Gordon C S Smith
BACKGROUND: It has been proposed that correction of offspring weight percentiles (customization) might improve the prediction of adverse pregnancy outcome; however, the approach is not accepted universally. A complication in the interpretation of the data is that the main method for calculation of customized percentiles uses a fetal growth standard, and multiple analyses have compared the results with birthweight-based standards. OBJECTIVES: First, we aimed to determine whether women who deliver small-for-gestational-age infants using a customized standard differed from other women...
December 1, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29198848/association-between-surgically-diagnosed-endometriosis-and-adverse-pregnancy-outcomes
#16
Innie Chen, Shifana Lalani, Ri-Hua Xie, Minxue Shen, Sukhbir S Singh, Shi-Wu Wen
OBJECTIVE: To examine the association between surgically diagnosed endometriosis and pregnancy outcomes in subsequent pregnancies. DESIGN: Retrospective cohort study of women who delivered a singleton live birth from 2003 to 2013 in Ottawa, Ontario, Canada. SETTING: Tertiary level academic center. PATIENT(S): Pregnant women with surgically diagnosed endometriosis were identified using International Classification of Diseases-10 codes from previous hospital admissions and were compared with pregnant women with no prior admission for endometriosis for the occurrences of adverse pregnancy outcomes...
November 29, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29198539/long-term-outcomes-of-hyperglycemic-preterm-infants-randomized-to-tight-glycemic-control
#17
Anna Catherine Tottman, Jane Marie Alsweiler, Frank Harry Bloomfield, Greg Gamble, Yannan Jiang, Myra Leung, Tanya Poppe, Benjamin Thompson, Trecia Ann Wouldes, Jane Elizabeth Harding
OBJECTIVE: To determine whether tight glycemic control of neonatal hyperglycemia changes neurodevelopment, growth, and metabolism at school age. STUDY DESIGN: Children born very low birth weight and randomized as hyperglycemic neonates to a trial of tight vs standard glycemic control were assessed at 7 years corrected age, including Wechsler Intelligence Scale for Children Fourth Edition, Movement Assessment Battery for Children 2, visual and neurologic examinations, growth measures, dual X-ray absorptiometry, and frequently sampled intravenous glucose tolerance test...
November 30, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29198051/doula-services-within-a-healthy-start-program-increasing-access-for-an-underserved-population
#18
Mary-Powel Thomas, Gabriela Ammann, Ellen Brazier, Philip Noyes, Aletha Maybank
PURPOSE: Women of color in the United States, particularly in high-poverty neighborhoods, experience high rates of poor birth outcomes, including cesarean section, preterm birth, low birthweight, and infant mortality. Doula care has been linked to improvements in many perinatal outcomes, but women of color and low-income women often face barriers in accessing doula support. DESCRIPTION: To address this issue, the New York City Department of Health and Mental Hygiene's Healthy Start Brooklyn introduced the By My Side Birth Support Program in 2010...
December 2, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29197867/topical-coconut-oil-in-very-preterm-infants-an-open-label-randomised-controlled-trial
#19
Tobias Strunk, Sameer Pupala, Julie Hibbert, Dorota Doherty, Sanjay Patole
BACKGROUND: The immature fragile skin of preterm infants represents an inadequate protective barrier. The emollient and anti-infective properties of coconut oil make it a potentially beneficial topical agent for this population. OBJECTIVES: Our aim was to evaluate feasibility, safety, and the effects of topical coconut oil on skin condition in very preterm infants. METHODS: An open-label randomised controlled trial in preterm infants <30 weeks' gestation was conducted...
December 1, 2017: Neonatology
https://www.readbyqxmd.com/read/29197251/-the-next-generation-long-term-reproductive-outcome-of-adults-born-at-a-very-low-birth-weight
#20
Lior Drukker, Ziona Haklai, Mor Ben-Yair Schlesinger, Maayan Bas-Lando, Ethel Sherry Gordon, Arnon Samueloff, Michael S Schimmel, Sorina Grisaru-Granovsky
BACKGROUND: Preterm birth at very low birth weight (VLBW, <1500g) has a multitude of consequences that extend to various aspects of adult life. Little is known about the long-term reproductive outcome of VLBW that survive to adulthood. AIMS: To evaluate the reproductive outcome of VLBW infants who survive to adulthood (next-generation). STUDY DESIGN: Retrospective cohort. SUBJECTS: Infants born at a single tertiary center between the years 1982-1997 who survived to 18years of age (first-generation)...
November 29, 2017: Early Human Development
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