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https://www.readbyqxmd.com/read/27904261/the-north-south-divide-in-snake-bite-envenomation-in-india
#1
REVIEW
Vivek Chauhan, Suman Thakur
Snake bite envenomations are common in rural areas and the incidence peaks during monsoons in India. Prominent venomous species have been traditionally labeled as the 'big four' that includes Cobra, Krait, Russel's viper and Saw scaled viper. Systematic attempts for identification and classification of prevalent snakes in various states of India are missing till now and there is no concrete data on this aspect. The published literature however shows that some species of snakes are more prevalent in a particular region than the other parts of India e...
October 2016: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/27903075/australian-taipan-oxyuranus-spp-envenoming-clinical-effects-and-potential-benefits-of-early-antivenom-therapy-australian-snakebite-project-asp-25
#2
Christopher I Johnston, Nicole M Ryan, Margaret A O'Leary, Simon G A Brown, Geoffrey K Isbister
CONTEXT: Taipans (Oxyuranus spp.) are medically important venomous snakes from Australia and Papua New Guinea. The objective of this study was to describe taipan envenoming in Australian and its response to antivenom. METHODS: Confirmed taipan bites were recruited from the Australian Snakebite Project. Data were collected prospectively on all snakebites, including patient demographics, bite circumstances, clinical effects, laboratory results, complications and treatment...
November 30, 2016: Clinical Toxicology
https://www.readbyqxmd.com/read/27902669/an-anaphylactoid-reaction-to-rattlesnake-envenomation-in-a-pediatric-patient
#3
Logan Rencher, Joanna Schwartz, Alexandra Wilson
Rattlesnake envenomation causes a spectrum of symptoms and signs, many of which closely resemble an anaphylactic reaction. Development of airway compromise after a snake bite to an extremity is unusual, but has been previously reported. The majority of such reports detail a history of probable sensitization from previous contact with snakes or snake venom. Few reports exist without such previous contact; no reports are of pediatric cases. Here we present a 14-year-old boy with no history of prior snake exposure who presents with an anaphylactoid reaction after a rattlesnake bite...
November 29, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27888371/protective-effect-of-the-sulfated-agaran-isolated-from-the-red-seaweed-laurencia-aldingensis-against-toxic-effects-of-the-venom-of-the-snake-lachesis-muta
#4
Ana Cláudia Rodrigues da Silva, Luciana Garcia Ferreira, Maria Eugênia Rabello Duarte, Mutue Toyota Fujii, Eladio Flores Sanchez, Miguel Daniel Noseda, André Lopes Fuly
Snakebite is a serious occupational hazard affecting mainly rural populations of tropical and subtropical developing countries. Lachesis muta (Bushmaster) bites are extremely serious but are rarely reported in the literature. Bushmaster envenomings are characterized by intense local pain, edema, neurotoxicity, hypotension, local hemorrhage, and dramatic systemic alterations. Antivenom treatment has regularly been used for more than a century; however, it fails to neutralize local tissue damage and hemorrhage, leading to morbidity or disabilities in victims...
November 25, 2016: Marine Biotechnology
https://www.readbyqxmd.com/read/27871786/ischemic-brain-infarcts-and-intracranial-haemorrhages-following-russell-s-viper-daboia-russelii-bite-in-sri-lanka
#5
R M M K Namal Rathnayaka, S A M Kularatne, K D M Kumarasinghe, Janaka Ranaweera, P E A Nishanthi Ranathunga
Snakebite is an important medical problem in Sri Lanka. Of the deadly venomous snakes, Russell's viper (Daboia russelii) is widely distributed and responsible for most of the fatalities of snakebite in the country. It is not uncommon to see atypical manifestations in Russell's viper bite. We report the events of intracranial haemorrhages and multiple ischemic brain infarcts following Russell's viper (Daboia russelii) bite of a previously healthy 43-years-old male who succumbed to envenoming.
November 19, 2016: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/27867095/identification-of-snake-venom-allergens-by-two-dimensional-electrophoresis-followed-by-immunoblotting
#6
Yujing Hu, Liming Yang, Haiwei Yang, Shaoheng He, Ji-Fu Wei
This allergic reaction to snake venom was described to occur in patients after recurrent exposure through bites in amateur and professional snake handlers, which might be underestimated and contribute to fatal snakebites in victim, independently from the toxicity of the venom itself. Few allergens were identified from snake venoms by normal SDS-PAGE, which cannot separate the snake venom completely. In the present study, we identified nine potential allergens by two-dimensional (2D) electrophoresis followed by immunoblotting (named as allergenomics) in Protobothrops mucrosquamatus venom...
November 17, 2016: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/27843867/ornament-induced-complications-in-snake-bites-revisiting-the-do-it-right-approach
#7
Subhendu Mallik, Sudipta Ranjan Singh, Sangeeta Sahoo, Manoj Kumar Mohanty
Limb adorning ornaments (LAO) can exacerbate the local effects of envenoming in case of venomous snake bite. Cultural presuppositions do inhibit victims from removing symbolically/ritually important jewelry even under circumstances that might increase the dangers of envenoming-induced gangrene formation. The recommendation to remove the LAO is usually skipped in guidelines and if at all included the very real hazard is uncommonly documented. We observed 14 cases of snake bite with LAO on the bitten limb with minimal to severe local complications...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27842799/safe-handling-of-snakes-in-an-ed-setting
#8
Melanie Cockrell, Kristofer Swanson, April Sanders, Samuel Prater, Toni von Wenckstern, JoAnn Mick
: Efforts to improve consistency in management of snakes and venomous snake bites in the emergency department (ED) can improve patient and staff safety and outcomes, as well as improve surveillance data accuracy. The emergency department at a large academic medical center identified an opportunity to implement a standardized process for snake disposal and identification to reduce staff risk exposure to snake venom from snakes patients brought with them to the ED. METHODS: A local snake consultation vendor and zoo Herpetologist assisted with development of a process for snake identification and disposal...
November 11, 2016: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://www.readbyqxmd.com/read/27828850/case-report-acute-demyelinating-encephalomyelitis-following-viper-bite
#9
Anyi Xu, Renfei Shan, Daochao Huang, Jiajia Zhou, Anaswasseem Keenoo, Jie Qin
The most serious complications of the central nervous system that occur after venomous snake bite are intracranial hemorrhage and ischemic stroke.We present a rarely seen central nervous system complication, acute demyelinating encephalomyelitis, after a treated Deinagkistrodon's viper bite.On April 5, 2015, a 50-year-old male farmer was bitten on his right leg by a Deinagkistrodon's viper. The bite rendered the victim unconscious for 14 days, during which he was treated with tetanus toxoid and polyvalent antisnake venom...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27826409/the-relaxant-effect-of-the-montivipera-bornmuelleri-snake-venom-on-vascular-contractility
#10
Claudine Accary, Souad Hraoui-Bloquet, Riyad Sadek, Asma Alameddine, Ziad Fajloun, Jean-Claude Desfontis, Yassine Mallem
Molecular richness of snake venoms is an important source of proteins and toxins with potent effects on the cardiovascular system. The alteration of the vascular system in the victim after a venomous snake bite is usually expressed by a significant decrease in blood pressure. Therefore, exploring snake venom to extract and characterize its biomolecules is of considerable medical interest, and formed the basis of this study. We assessed the potential of the venom of Montivipera bornmuelleri, a viper from Lebanon, to induce relaxant effect on isolated Wistar rat aorta via several mechanisms of action...
2016: Journal of Venom Research
https://www.readbyqxmd.com/read/27806970/snake-bite-mortality-in-children-beyond-bite-to-needle-time
#11
M P Jayakrishnan, M G Geeta, P Krishnakumar, T V Rajesh, Biju George
OBJECTIVE: To study the clinical characteristics and predictors of mortality from snake bite envenomation in children. DESIGN: Prospective observational study with a one-group cohort design. SETTING: Paediatric intensive care unit of a tertiary care hospital in South India. SUBJECTS: The study cohort consisted of 145 children (55 girls and 90 boys) <12 years of age with snake bite envenomation. METHODS: Demographic and clinical details were recorded in a semistructured pro forma...
November 2, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27800086/snakebite-in-bedroom-kills-a-physician-in-cameroon-a-case-report
#12
Armand Nkwescheu, Leopold Cyriaque Donfack Mbasso, Franky Baonga Ba Pouth, Anastase Dzudie, Serge Clotaire Billong, Hermann Ngouakam, Joseph Le Doux Diffo, Hanny Eyongorock, Wilfred Mbacham
The World Health Organization (WHO) classifies snake bites as neglected public health problem affecting mostly tropical and subtropical countries. In Africa there are an estimated 1 million snake bites annually with about half needing a specific treatment. Women, children and farmers in poor rural communities in developing countries are the most affected. Case management of snake bites are not adequate in many health facilities in developing countries where personnel are not always abreast with the new developments in snake bite management and in addition, quite often the anti-venom serum is lacking...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27774416/a-randomized-ethnomedicinal-survey-of-snakebite-treatment-in-southwestern-parts-of-bangladesh
#13
Md Nazmul Hasan, Nur Kabidul Azam, Md Nasir Ahmed, Akinori Hirashima
Snakebite is the single most important toxin-related injury, causing substantial mortality in many parts of the Africa, Asia and the Americas. Incidence of snakebite is usually recorded in young people engaged in active physical work in rural areas. The various plant parts used to treat snakebite included whole plant, leaves, barks, roots and seeds. Most bites in Bangladesh are recorded between May and October with highest number in June. Lower and upper limbs are most common sites of snakebite, but it may happen in other sites as well...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27762105/clinical-profile-and-laboratory-parameters-in-1051-victims-of-snakebite-from-a-single-centre-in-kerala-south-india
#14
J C Menon, J K Joseph, M P Jose, B L Dhananjaya, O V Oommen
INTRODUCTION: Snakebite is an occupational hazard causing considerable morbidity and mortality worldwide, particularly so in tropical countries like India. OBJECTIVE: The aim of this study is to (i) review the demographic, clinical and laboratory findings in patients (1051) admitted with venomous snakebite (ii) to correlate mortality, morbidity and duration of hospital stay with clinical signs, symptoms and laboratory parameters. METHODS: A retrospective study of 1051 patients treated for snakebite over 10 years (2000 - 2009) in Little Flower Hospital, Angamaly, Kerala...
August 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27752013/transient-distal-renal-tubular-acidosis-following-hump-nosed-viper-bite-two-cases-from-sri-lanka
#15
Ranga M Weerakkody, Pushpa N Lokuliyana, Ruchika D Lanerolle
Hump-nosed viper (Hypnale hypnale; HNV) is one of the six major snake species in Sri Lanka that cause envenomation. Nephrotoxicity, coagulopathy, and neurotoxicity are wellrecognized features of its envenomation. Type 4 renal tubular acidosis (RTA4) has only once been described previously in this condition, and we report two further cases. Two patients aged 53 and 51 presented following HNV bites with acute kidney injury and microangiopathic hemolytic anemia. Both underwent multiple cycles of hemodialysis until the polyuric phase was reached...
September 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27749906/the-treatment-of-snake-bites-in-a-first-aid-setting-a-systematic-review
#16
Bert Avau, Vere Borra, Philippe Vandekerckhove, Emmy De Buck
BACKGROUND: The worldwide burden of snakebite is high, especially in remote regions with lesser accessibility to professional healthcare. Therefore, adequate first aid for snakebite is of the utmost importance. A wide range of different first aid techniques have been described in literature, and are being used in practice. This systematic review aimed to summarize the best available evidence concerning effective and feasible first aid techniques for snakebite. METHODS: A systematic literature screening, performed independently by two authors in the Cochrane Library, MEDLINE and Embase resulted in 14 studies, fulfilling our predefined selection criteria, concerning first aid techniques for snakebite management...
October 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27749012/injury-trends-from-envenoming-in-australia-2000-2013
#17
Ronelle E Welton, David J Williams, Danny Liew
BACKGROUND: This study provides the first contemporary epidemiological insight into venomous injuries based on demographics and geography in Australia in the timeframe 2000-2013. METHODS: Analysis of national hospitalisation and mortality data to examine the incidence of injury and death due to envenoming in Australia. Rates were calculated using the intercensal population for all Australian age groups. RESULTS: Over the study period, deaths were due to an anaphylactic event (0...
October 17, 2016: Internal Medicine Journal
https://www.readbyqxmd.com/read/27727935/comparison-of-two-anti-snake-venom-protocols-in-hemotoxic-snake-bite-a-randomized-trial
#18
Pramod Sagar Bk, Chanaveerappa Bammigatti, R P Swaminathan
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27722112/mass-awareness-regarding-snake-bite-induced-early-morning-neuroparalysis-can-prevent-many-deaths-in-north-india
#19
Rupinder Sharma, Varundeep Dogra, Gurudutt Sharma, Vivek Chauhan
INTRODUCTION: In North India snake bite deaths are predominantly seen with neurotoxic envenomations (NEs) whereas in South India the hemotoxic envenomation (HE) is more common. Krait is responsible for most deaths in North India. It bites people sleeping on the floors, mostly at night. We describe the profile of venomous snake bites over 1 year in 2013. MATERIALS AND METHODS: The study was conducted in a rural tertiary care hospital in North India. Demographics, circumstances of bite, envenomation, first aid, delay, consultation, treatment, anti-venom, and outcomes were recorded for all victims of snake bite...
July 2016: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/27720975/identification-of-antinociceptive-fraction-of-snake-venom-from-crotalus-durissus-collilineatus-crotamine-negative-and-its-acute-toxicity-evaluation
#20
Sayonara Ay More de Oliveira, Marta Regina Magalhães, Lilibete P de Oliveira, Luiz Carlos da Cunha
The crude venom of the snake Crotalus durissus collilineatus (CDC) promotes neurological signs and symptoms in accidents involving humans and animals and the victims reports analgesia at the bite site, without tissue destruction. Studies shows that CDC has analgesic activity, among others. The crude venom is considered unsuitable for therapeutic purposes, with encouragement to the fractionation and purification of the same. Thus, the aim with CDC venom is: to perform fractionation by preparative HPLC; to test the antinociceptive activity of fractions and acute toxicity of active fractions...
November 2016: Toxicon: Official Journal of the International Society on Toxinology
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