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Mullerian anomalies

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https://www.readbyqxmd.com/read/29553867/functioning-left-uterine-horn-with-cervico-vaginal-atresia-and-ovarian-maldescent-an-unclassified-m%C3%A3-llerian-anomaly-treated-with-horn-vaginal-anastomosis
#1
Rashmi Bagga, Tanuja Muthyala, Pradeep Kumar Saha, Jasvinder Kalra, Rimpi Singla, Aashima Arora, Tulika Singh
No abstract text is available yet for this article.
March 19, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29549434/female-genital-tract-congenital-malformations-and-the-applicability-of-the-eshre-esge-classification-a-systematic-retrospective-analysis-of-920-patients
#2
Dorit Schöller, Marieke Hölting, Diana Stefanescu, Helen Burow, Birgitt Schönfisch, Katharina Rall, Florin-Andrei Taran, Grigoris F Grimbizis, Attilio Di Spiezio Sardo, Sara Y Brucker
PURPOSE: Several classification systems for female genital tract anomalies exist but are of limited use in clinical practice. We, therefore, assessed the applicability and ease of use of the new ESHRE/ESGE classification, using only patient records. METHODS: This retrospective, single-center, proof-of-principle study systematically analyzed the surgical reports and other hospital records of 920 inpatients and outpatients treated for confirmed female genital tract congenital malformations at a major German university hospital during 2003-2013...
March 16, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29531007/uterus-septus-subtotalis-bicollis-a-rare-mullerian-duct-abnormality
#3
Paloma Del C Monroig-Bosque, Ekene I Okoye
Mullerian duct anomalies (MDAs) are congenital defects of the female genital system that arise from abnormal embryological development of the Mullerian ducts. Septate uterus is the most common, resulting from incomplete resorption of the medial septum after fusion of the Mullerian ducts. Two main types of septate uterus exist, including septa that extend completely or partially from the uterine fundus to the cervical os. The combination of a uterine septum with a double cervix has been previously described; however, in most cases the septum was complete...
January 2018: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/29479403/uncommon-presentations-of-an-uncommon-entity-ohvira-syndrome-with-hematosalpinx-and-pyocolpos
#4
Z Sleiman, T Zreik, R Bitar, R Sheaib, A Al Bederi, V Tanos
Müllerian malformations result from defective fusion of the Müllerian ducts during development of the female reproductive system. The least common form of these malformations is Herlyn-Werner-Wunderlich syndrome characterized by obstructed hemivagina and ipsilateral renal anomaly (OHVIRA). The most common presentation of this syndrome is a mass secondary to hematocolpos, pain, and dysmenorrhea. Clinical diagnosis is very challenging and requires imaging studies in which ultrasound and MRI play an essential role in the diagnosis, classification and treatment plan...
September 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29472419/a-womb-like-a-broken-heart
#5
Amenda Ann Davis
Uterine perforation during hysteroscopic operative procedures is a potential complication well known to gynaecologists. Uterine septa are a commonly encountered Müllerian anomaly related to pregnancy loss and infertility. Hysteroscopic resection of septa has shown to improve pregnancy outcome. There are limited case reports of uterine rupture in subsequent pregnancies after hysteroscopic septal resection. Our patient had a hysteroscopic septal resection done a year prior which was complicated by a uterine fundal perforation, left to spontaneously heal after immediate sealing with cautery...
February 22, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29459133/screening-for-mullerian-anomalies-in-patients-with-unilateral-renal-agenesis-leveraging-early-detection-to-prevent-complications
#6
M Alexandra Friedman, Liza Aguilar, Quetrell Heyward, Carol Wheeler, Anthony Caldamone
BACKGROUND: Mullerian anomalies have a known association with renal agenesis yet, to date, there are no formal recommendations for screening women with certain renal anomalies for associated genital tract disorders. OBJECTIVE: The objective of this study is to review current data regarding the association between renal and Mullerian anomalies, and propose screening recommendations. STUDY DESIGN: A comprehensive review of the literature was performed to identify relevant articles using the keywords "unilateral renal agenesis," "renal anomalies," and "Mullerian anomalies...
February 9, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29447701/mullerian-anomaly-with-pelvic-pain
#7
Christopher Lusty, Angelos Vilos, George Vilos
No abstract text is available yet for this article.
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29415121/mayer-rokitansky-kuster-hauser-syndrome-a-unique-case-presentation
#8
Bao T Nguyen, Katherine L Dengler, Rhiana D Saunders
Background: Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a congenital condition characterized by aplasia of the vagina with or without concurrent uterine and/or cervical aplasia. Type II (MURCS) is a rare form involving MUllerian agenesis, Renal agenesis, and Cervicothoracic Somite anomalies. Case: A 17-yr-old virginal female presented for evaluation of primary amenorrhea and pelvic pain. Her medical history was significant for a bicuspid aortic valve and right radial dysplasia...
February 5, 2018: Military Medicine
https://www.readbyqxmd.com/read/29392437/independent-association-between-uterine-malformations-and-cervical-insufficiency-a-retrospective-population-based-cohort-study
#9
Salvatore Andrea Mastrolia, Yael Baumfeld, Reli Hershkovitz, David Yohay, Giuseppe Trojano, Adi Y Weintraub
OBJECTIVE: The purpose of our study was to explore maternal and fetal outcomes in the second and third trimester in women with uterine malformations. STUDY DESIGN: This was a retrospective population-based cohort study including women with a diagnosis of uterine malformation arised from workup for infertility or recurrent pregnancy loss, was accidental during pregnancy, or was noticed at the time of cesarean delivery. RESULTS: A total of 280,721 pregnancies met the inclusion criteria and were divided into two study groups: (1) pregnancies in women with uterine malformations (n = 1099); and (2) controls (n = 279,662)...
February 1, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29368901/-unicornuate-uterus-with-cavitary-non-communicating-rudimentary-horn-magnetic-resonance-characterization
#10
Jenny Del Rocío Chamorro-Oscullo, Julián Antonio Sánchez-Cortázar, María de Guadalupe Gómez-Pérez
Mullerian duct or paramesonephric anomalies are a group of congenital malformations of the female genital tract that result from the alteration in one or more stages of embryonic development. The prevalence has increased, probably due to the progress of diagnostic imaging methods and the relevance that it has acquired in young women with infertility problems. Magnetic resonance imaging (MRI) is currently the method of choice for characterizing the different types of Mullerian anomalies, its complications and associated pathology...
January 2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29363367/the-association-between-mullerian-anomalies-and-iugr-a-meta-analysis
#11
Manoochehr Karami, Ensiyeh Jenabi
BACKGROUND: Published literature regarding the association between Mullerian anomalies and intrauterine growth restriction (IUGR) is controversial. To date, no meta-analysis has been performed for assessing the relationship between the Mullerian anomalies and IUGR. Therefore, the aim of this study was to perform a meta-analysis by combining data from relevant studies to assessing the association of between Mullerian anomalies and IUGR. METHODS: A systematic search was conducted in PubMed, Scopus and Web of Science to identify of all studies prior to September 2017...
February 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29281142/m%C3%A3-llerian-tract-anomalies-and-urinary-tract-infections
#12
LETTER
Penelope J Teoh, Alexandra Ridout, Jenny Carter, Andrew H Shennan
No abstract text is available yet for this article.
March 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29241916/etiology-and-management-of-primary-amenorrhoea-a-study-of-102-cases-at-tertiary-centre
#13
Alka Kriplani, Manu Goyal, Garima Kachhawa, Reeta Mahey, Vidushi Kulshrestha
OBJECTIVE: To determine the prevalence of etiologic causes of primary amenorrhea in Indian population. MATERIALS AND METHODS: A retrospective study was performed using 102 complete medical records of women with primary amenorrhea who attended the Gynaecologic Endocrinology Clinic, Department of Obstetrics and Gynaecology, AIIMS, New Delhi from September 2012 to September 2015. Cases were analysed according to clinical profile, development of secondary sexual characteristics, physical examination, pelvic and rectal examination, X-ray of chest and lumbo-sacral spine, hormone profile, pelvic USG, MRI, and cytogenetic study including karyotype...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29234256/congenital-malformations-of-the-reproductive-tract-in-a-patient-with-poland-syndrome-is-there-a-connection
#14
Tian Meng, Ming Bai, Ru Zhao
Background: Poland syndrome and Müllerian duct agenesis (Mayer-Rokitansky-Küster-Hauser(MRKH)-like syndrome) are two rare congenital anomalies with unclear etiology. Case Report: An 18-year-old female presented with hypoplasia of the left pectoralis muscles and subcutaneous tissue, hypoplasia of the left breast and nipple, and dextrocardia, typical in those with a severe form of Poland syndrome. She also showed aplasia of the vagina and uterus, bilateral ovarian agenesis, and hyperandrogenism, presenting as MRKH-like syndrome...
October 2017: Breast Care
https://www.readbyqxmd.com/read/29229001/a-novel-mutation-of-hoxa11-in-a-patient-with-septate-uterus
#15
Ying Zhu, Zhi Cheng, Jing Wang, Beihong Liu, Longfei Cheng, Beili Chen, Yunxia Cao, Binbin Wang
BACKGROUND: The etiology of Müllerian duct anomalies (MDAs) is poorly understood at present. The HOXA11 gene is crucial for the development of the Müllerian duct. The objective of this study is to report a unique case of MDAs with a novel mutation in HOXA11. RESULTS: We identified a potential disease-causing mutation (p. E255K) in a patient with a septate uterus. The mutation was not detected in 169 control subjects or listed in any databases of variations. Bioinformatic predictions and functional studies showed that the mutation reduces the DNA binding affinity and disrupts transactivation ability of HOXA11...
December 11, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29162069/martius-flap-for-recurrent-perineal-and-rectovaginal-fistulae-in-a-patient-with-crohn-s-disease-endometriosis-and-a-mullerian-anomaly
#16
Gaetano Gallo, Alberto Realis Luc, Giuseppe Clerico, Mario Trompetto
BACKGROUND: Rectovaginal fistulas represent 5% of all anorectal fistulae and are a disastrous manifestation of Crohn's disease that negatively affects patients' social and sexual quality of life. Treatment remains challenging for colorectal surgeons, and the recurrence rate remains high despite the numerous available options. CASE PRESENTATION: We describe a 31-year-old female patient with a Crohn's disease-related recurrent perineo-vaginal and recto-vaginal fistulae and a concomitant mullerian anomaly...
November 21, 2017: BMC Surgery
https://www.readbyqxmd.com/read/29155007/rare-obstructive-m%C3%A3-llerian-anomaly-with-endometriosis-and-elevated-ca-125
#17
Christina H Suh, Yi-Horng Lee, Adrian C Balica
No abstract text is available yet for this article.
November 15, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29142454/successful-reproductive-outcome-after-laparoscopic-strassmann-s-metroplasty
#18
S D S Karthik, Alka Kriplani, Reeta Mahey, Garima Kachhawa
Mullerian anomalies cause a significant impact on the reproductive outcomes. A bicornuate uterus is a type of lateral fusion defect, which constitutes 26% of all uterine anomalies. Strassmann's metroplasty is a unification procedure performed to correct the two smaller uterine cavities into a more spacious single cavity. Improved reproductive performance was reported after unification metroplasty. Laparoscopic route can be adopted for this procedure with all the advantages of minimally invasive surgery. Here, we report a success story of a woman who suffered with six miscarriages and secondary infertility who underwent laparoscopic Strassmann's metroplasty in a tertiary care center and later delivered a baby by caesarean section...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29068465/array-cgh-analysis-in-patients-with-m%C3%A3-llerian-fusion-anomalies
#19
S Ledig, A C Tewes, J Hucke, T Römer, K Kapczuk, C Schippert, P Hillemanns, P Wieacker
Fusion anomalies of the Müllerian ducts are associated with an increased risk for miscarriage and premature labor. In most cases polygenic-multifactorial inheritance can be assumed but autosomal-dominant inheritance with reduced penetrance and variable manifestation should be considered. We performed array-CGH (comparative genomic hybridization) analysis in a cohort of 103 patients with Müllerian fusion anomalies. In eight patients we detected microdeletions and microduplications in chromosomal regions 17q12, 22q11...
October 25, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/29043712/uterus-dysplasia-associated-with-cervico-vaginal-agenesis
#20
Ali Mahdavi, Hadi Mirfazaelian, Ladan Younesi Asl, Zeynab Hasani, Maryam Bahreini
Müllerian ducts can form upper parts of normal female reproductive system and any failure in ductal fusion may result in to müllerian duct anomalies (MDA). We present a case of MDA and a uterus dysplasia with no evidence of cervical or upper vaginal tissue. This case showes the role of magnetic resonace imaging (MRI) on MDA diagnosis and urges the need for a unified reliable and practical classification more compatible with clinical practice.
January 2018: International Journal of Fertility & Sterility
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