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MRI endometriosis

Baptiste Couvy-Duchesne, Victoria O'Callaghan, Richard Parker, Natalie Mills, Katherine M Kirk, Jan Scott, Anna Vinkhuyzen, Daniel F Hermens, Penelope A Lind, Tracey A Davenport, Jane M Burns, Melissa Connell, Brendan P Zietsch, James Scott, Margaret J Wright, Sarah E Medland, John McGrath, Nicholas G Martin, Ian B Hickie, Nathan A Gillespie
PURPOSE: The Nineteen and Up study (19Up) assessed a range of mental health and behavioural problems and associated risk factors in a genetically informative Australian cohort of young adult twins and their non-twin siblings. As such, 19Up enables detailed investigation of genetic and environmental pathways to mental illness and substance misuse within the Brisbane Longitudinal Twin Sample (BLTS). PARTICIPANTS: Twins and their non-twin siblings from Queensland, Australia; mostly from European ancestry...
March 17, 2018: BMJ Open
P Collinet, X Fritel, C Revel-Delhom, M Ballester, P A Bolze, B Borghese, N Bornsztein, J Boujenah, N Bourdel, T Brillac, N Chabbert-Buffet, C Chauffour, N Clary, J Cohen, C Decanter, A Denouël, G Dubernard, A Fauconnier, H Fernandez, T Gauthier, F Golfier, C Huchon, G Legendre, J Loriau, E Mathieu-d'Argent, B Merlot, J Niro, P Panel, P Paparel, C A Philip, S Ploteau, C Poncelet, B Rabischong, H Roman, C Rubod, P Santulli, M Sauvan, I Thomassin-Naggara, A Torre, J M Wattier, C Yazbeck, M Canis
First-line investigations to diagnose endometriosis are clinical examination and pelvic ultrasound. Second-line investigations include pelvic examination performed by a referent clinician, transvaginal ultrasound performed by a referent, and pelvic MRI. It is recommended to treat endometriosis when it is symptomatic. First-line hormonal treatments recommended for the management of painful endometriosis are combined hormonal contraceptives or levonorgestrel 52mg IUD. There is no evidence to recommend systematic preoperative hormonal therapy for the unique purpose of preventing the risk of surgical complications or facilitating surgery...
March 14, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
A Fauconnier, B Borghese, C Huchon, I Thomassin-Naggara, C-A Philip, T Gauthier, N Bourdel, A Denouel, A Torre, P Collinet, M Canis, X Fritel
Based on the best evidence available, we have provided guidelines for clinical practice to target the nature of endometriosis as a disease, the consequences of its natural history on management, and the clinical and imaging evaluation of the disease according to the level of care (primary care, specialized or referral). The frequency of endometriosis is unknown in the general population; endometriosis requires management when it causes symptoms (pain, infertility) or when it affect the function of an organ...
March 13, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
C-A Philip, G Dubernard
Endometriosis is difficult to diagnose clinically. Transvaginal sonography (TVS) is a procedure that is known to be operator-dependent, which mean that published evidences has to be balanced with the level of the sonographer that produced the data. The objective of this publication was to assess the performances of the sonography in the diagnosis of endometriosis in order to establish the French national recommendations. We searched the MEDLINE database for publication from January 2000 to September 2017 using keywords associated with endometriosis and sonography...
March 12, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
I Thomassin-Naggara, S Bendifallah, P Rousset, M Bazot, M Ballester, E Darai
Diagnostic performance of MR imaging for the diagnosis of pelvic endometriosis are good. Even if some differences of performances exists according the location considered, the risk of misdiagnosis is lower than 10% for trained teams (NP2). The performance of pelvic MR imaging and surgery are quite similar to diagnose endometrioma (sensitivity and specificity>90%). A negative pelvic MR imaging allows to exclude deep pelvic endometriosis with a performance similar to surgery but a positive MR imaging is less accurate than surgery because of a high number of false positives (23%)...
March 11, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
Saeed Alborzi, Alireza Rasekhi, Zahra Shomali, Gooya Madadi, Mahshid Alborzi, Mahboobeh Kazemi, Azam Hosseini Nohandani
To determine the diagnostic accuracy of pelvic magnetic resonance imaging (MRI), transvaginal sonography (TVS), and transrectal sonography (TRS) in diagnosis of deep infiltrating endometriosis (DIE).This diagnostic accuracy study was conducted during a 2-year period including a total number of 317 patients with signs and symptoms of endometriosis. All the patients were evaluated by pelvic MRI, TVS, and TRS in the same center. The criterion standard was considered to be the laparoscopy and histopathologic examination...
February 2018: Medicine (Baltimore)
Pietro Valerio Foti, Renato Farina, Stefano Palmucci, Ilenia Anna Agata Vizzini, Norma Libertini, Maria Coronella, Saveria Spadola, Rosario Caltabiano, Marco Iraci, Antonio Basile, Pietro Milone, Antonio Cianci, Giovanni Carlo Ettorre
OBJECTIVE: We illustrate the magnetic resonance imaging (MRI) features of endometriosis. BACKGROUND: Endometriosis is a chronic gynaecological condition affecting women of reproductive age and may cause pelvic pain and infertility. It is characterized by the growth of functional ectopic endometrial glands and stroma outside the uterus and includes three different manifestations: ovarian endometriomas, peritoneal implants, deep pelvic endometriosis. The primary locations are in the pelvis; extrapelvic endometriosis may rarely occur...
February 15, 2018: Insights Into Imaging
Louis Marcellin, Pietro Santulli, Sara Bortolato, Cécile Morin, Anne Elodie Millisher, Bruno Borghese, Charles Chapron
STUDY OBJECTIVE: To evaluate the association between bladder deep infiltrating endometriosis (DIE) and anterior focal adenomyosis of the outer myometrium (aFAOM) diagnosed by preoperative magnetic resonance imaging (MRI). DESIGN: An observational, cross-sectional study using prospectively collected data (Canadian Task Force classification II-2). SETTING: Single university tertiary referral center. PATIENTS: All non-pregnant women less than 42-years-old who had undergone complete surgical exeresis of endometriotic lesions...
February 9, 2018: Journal of Minimally Invasive Gynecology
Kevin M Hellman, Caroline S Kuhn, Frank F Tu, Katlyn E Dillane, Nathan A Shlobin, Sangeeta Senapati, Xiaojie Zhou, Wei Li, Pottumarthi V Prasad
BACKGROUND: The lack of non-invasive methods to study dysmenorrhea has resulted in poor understanding of the mechanisms underlying pain, insufficient diagnostic tests, and limited treatment options. To address this knowledge gap, we have developed an MRI-based strategy for continuously monitoring the uterus in relation to participants' spontaneous pain perception. OBJECTIVE: The study objective was to evaluate whether MRI can detect real-time changes in myometrial activity during cramping episodes in women with dysmenorrhea, with a hand-held squeeze bulb for pain reporting...
January 31, 2018: American Journal of Obstetrics and Gynecology
Claudia Mehedințu, Lăcrămioara Aurelia Brîndușe, Elvira Brătilă, Michele Monroc, Ebticem Lemercier, Olivier Suaud, Cecile Collet-Savoye, Horace Roman
STUDY OBJECTIVE: To evaluate whether combining Computed Tomography-based virtual Colonoscopy (CTC) with Magnetic Resonance Imaging (MRI) improves preoperative assessment of colorectal endometriosis. DESIGN: Retrospective study using prospectively recorded data (Canadian Task Force classification II-2). SETTING: University tertiary referral center. PATIENTS: Seventy-one women treated for colorectal endometriosis managed between June 2015 and May 2016...
January 25, 2018: Journal of Minimally Invasive Gynecology
Philippa Nelson
A 43-year-old woman with an anterior vaginal wall mass was referred to gynaecology outpatient for diagnosis and management. Clinical assessment was indicative of a urethral diverticulum, however MRI and ultrasound imaging suggested a Gartner's duct cyst. Following excision of the lesion, histology revealed evidence of an endometriotic cyst. The patient had no other symptoms of endometriosis and remained asymptomatic 3 months following excision. This case highlights the widespread locations in which endometrial tissue can be found, and therefore the range of symptomatology...
January 23, 2018: BMJ Case Reports
Faik Tatli, Orhan Gozeneli, Hacer Uyanikoglu, Ali Uzunkoy, Huseyin Cahit Yalcın, Abdullah Ozgonul, Osman Bardakci, Adnan Incebiyik, Muhammet Emin Guldur
Abdominal wall endometriosis (AWE) is a rare form of endometriosis that usually develops in the scar after cesarean section (CS). Recently, the occurrence of AWE has been increasing together with the increase of CS incidence. AWE can be clinically misdiagnosed as hernia, lipoma, or hematoma. Here we retrospectively analyzed the clinical aspects of AWE and surgical approach in 14 patients from a tertiary hospital, who were treated by surgery, between 2012 and 2017. The mean age was 32.71 ± 8.61 years (range: 19-45)...
December 29, 2017: Bosnian Journal of Basic Medical Sciences
Dpa Van den Nouland, M Kaur
Primary umbilical endometriosis is a rare phenomenon accounting for 0,4-1,0% of extragenital endometriosis. Despite the fact that it mostly presents as a typical cyclic umbilical discharge coincidental with a palpable mass, the diagnosis is often delayed due to its low prevalence, as was seen in the presented case. The exact pathogenesis is still unclear. The golden standard for diagnosis is histopathological examination, but diagnostic tools like ultrasound, MRI or CT scan can be helpful. The differential diagnosis includes a wide range of disorders...
June 2017: Facts, Views & Vision in ObGyn
Marc Bazot, Emile Daraï
The aim of the present review was to evaluate the contribution of clinical examination and imaging techniques, mainly transvaginal sonography and magnetic resonance imaging (MRI) to diagnose deep infiltrating (DE) locations using prisma statement recommendations. Clinical examination has a relative low sensitivity and specificity to diagnose DE. Independently of DE locations, for all transvaginal sonography techniques a pooled sensitivity and specificity of 79% and 94% are observed approaching criteria for a triage test...
December 2017: Fertility and Sterility
Stefano Guerriero, Juan Luis Alcázar, Maria Angela Pascual, Silvia Ajossa, Maura Perniciano, Alba Piras, Valerio Mais, Bruno Piras, Federica Schirru, Melis Gian Benedetto, Luca Saba
OBJECTIVES: To evaluate the diagnostic accuracy of 2-dimensional (2D) and 3-dimensional (3D) transvaginal ultrasonography (US) in comparison with magnetic resonance imaging (MRI) for identification of deep infiltrating endometriosis. METHODS: In this prospective observational study, 159 premenopausal women who underwent surgery for a clinical suspicion of deep infiltrating endometriosis were prospectively enrolled. All women underwent 2DUS, 3DUS, and MRI. The following 3 locations of deep endometriosis were considered: (1) intestinal; (2) other posterior lesions (retrocervical septum, rectovaginal septum, uterosacral ligaments, and vaginal fornix); and (3) anterior...
November 30, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Krystel Nyangoh Timoh, Zelda Stewart, Mikhael Benjoar, Selma Beldjord, Marcos Ballester, Marc Bazot, Isabelle Thomassin-Naggara, Emile Daraï
STUDY OBJECTIVE: To prospectively determine the accuracy of magnetic resonance enterography (MRE) compared with conventional magnetic resonance imaging (MRI) for multifocal (i.e., multiple lesions affecting the same digestive segment) and multicentric (i.e., multiple lesions affecting several digestive segments) bowel endometriosis. DESIGN: Prospective study (Canadian Task Force classification II-2). SETTING: Tenon University Hospital, Paris, France...
November 17, 2017: Journal of Minimally Invasive Gynecology
S Guerriero, L Saba, M A Pascual, S Ajossa, I Rodriguez, V Mais, J L Alcazar
OBJECTIVES: To perform a systematic review of studies comparing the diagnostic accuracy of TVS and MRI in Deep Infiltrating Endometriosis (DIE) including only studies in which patients have been underwent both techniques. METHODS: An extensive search of papers comparing TVS and MRI in DIE was performed in Medline (Pubmed) and Web of Sciences from January 1989 to January 2016. Studies were considered eligible if they reported on the use of TVS and MRI in the same set of patients for the preoperative detection of endometriosis in pelvic locations in women with clinical suspicion of DIE using the surgical data as a reference standard...
November 20, 2017: Ultrasound in Obstetrics & Gynecology
Isabelle Thomassin-Naggara, Edith Kermarrec, Selma Beldjord, Marc Bazot, Sebastian Tavolaro, Emile Darai
The diagnosis of pelvic endometriosis is based on the combination of clinical examination, endovaginal ultrasonography and pelvic MRI. Ultrasonography displays a moderate sensitivity and a high specificity. Pelvien MRI displays a better sensitivity and lower specificity.
December 2017: La Presse Médicale
Arnaldo Scardapane, Filomenamila Lorusso, Mariantonietta Francavilla, Stefano Bettocchi, Fabiana Divina Fascilla, Giuseppe Angelelli, Marco Scioscia
Purpose: To define if MRI findings in patients with deep pelvic endometriosis (DPE) may be predictive for the need of bowel resection. Material and Methods: A retrospective survey of 196 pelvic MRIs of women who received laparoscopic procedures for DPE was carried out. A pelvic MRI was performed in all patients: it consisted in T2w-TSE sequences in axial, sagittal, and coronal planes and T1w and THRIVE sequences in the axial plane; the exam was completed by MR-Colonography...
2017: BioMed Research International
Maria Grazia Porpora, Valeria Vinci, Corrado De Vito, Giuseppe Migliara, Emanuela Anastasi, Adele Ticino, Serena Resta, Carlo Catalano, Pierluigi Benedetti Panici, Lucia Manganaro
OBJECTIVES: To evaluate the sacral nerve root features by the means of magnetic resonance imaging-diffusion tensor imaging (MRI-DTI) tractography in women with endometriosis and/or adenomyosis, and to analyze the correlations among DTI abnormalities, pain symptoms, and endometriotic lesions found at surgery. DESIGN: A cross-sectional, observational study (Canadian Task Force classification II-2). SETTING: University hospital. PATIENTS: Women (n = 76) with clinical suspicion of endometriosis...
November 8, 2017: Journal of Minimally Invasive Gynecology
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