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https://www.readbyqxmd.com/read/29135868/endoscopic-transcanal-transpromontorial-approach-for-vestibular-schwannoma-resection-a-case-series
#1
Cameron C Wick, Demetri Arnaoutakis, Samuel L Barnett, Alejandro Rivas, Brandon Isaacson
OBJECTIVE: To demonstrate successful surgical management of vestibular schwannomas via an exclusively endoscopic transcanal transpromontorial approach (EETTA). PATIENTS: Four patients with vestibular schwannomas. INTERVENTIONS: Surgical excision via EETTA. MAIN OUTCOMES: Technique refinements, tumor access, complete tumor removal, and patient morbidity. RESULTS: Three tumors were Koos grade I and one tumor was Koos grade II...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29098278/cranioplasty-using-a-mixture-of-biologic-and-nonbiologic-agents
#2
Demetri Arnaoutakis, Arash Bahrami, Jason E Cohn, Jesse E Smith
Importance: A surgeon faces challenges with cranioplasty techniques to achieve a successful result with relatively few complications. Objective: To describe a unique technique for incorporating both biologic autologous bone and nonbiologic allograft materials for defect coverage in cranioplasty with favorable outcomes and low occurrence of complications. Design, Setting, and Participants: A retrospective medical records review of all 26 patients who underwent primary cranioplasty procedure with a modified technique between January 2011 and December 2015 at a high-volume head and neck oncologic reconstructive practice was conducted; data analysis was also performed during that period...
November 2, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29075160/osseointegrated-implants-and-prosthetic-reconstruction-following-skull-base-surgery
#3
REVIEW
Shirley Hu, Demetri Arnaoutakis, Sameep Kadakia, Allison Vest, Raja Sawhney, Yadranko Ducic
Rehabilitation following ablative skull base surgery remains a challenging task, given the complexity of the anatomical region, despite the recent advances in reconstructive surgery. Remnant defects following resection of skull base tumors are often not amenable to primary closure. As such, numerous techniques have been described for reconstruction, including local rotational muscle flaps, pedicled flaps with skin paddle, or even free tissue transfer. However, not all patients are appropriate surgical candidates and therefore may instead benefit from nonsurgical options for functional and aesthetic restoration...
November 2017: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/29075158/locoregional-and-microvascular-free-tissue-reconstruction-of-the-lateral-skull-base
#4
REVIEW
Demetri Arnaoutakis, Sameep Kadakia, Manoj Abraham, Thomas Lee, Yadranko Ducic
The goals of reconstruction following any oncologic extirpation are preservation of function, restoration of cosmesis, and avoidance of morbidity. Anatomically, the lateral skull base is complex and conceptually intricate due to its three-dimensional morphology. The temporal bone articulates with five other cranial bones and forms many sutures and foramina through which pass critical neural and vascular structures. Remnant defects following resection of lateral skull base tumors are often not amenable to primary closure...
November 2017: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/28927164/hyalinizing-clear-cell-carcinoma-of-the-lung-case-report-and-review-of-the-literature
#5
REVIEW
Susanne K Jeffus, Jerad M Gardner, Matthew A Steliga, Akeesha A Shah, Edward B Stelow, Konstantinos Arnaoutakis
Objectives: Hyalinizing clear cell carcinoma (HCCC) is common in head and neck sites but extremely rare in the lung. This case report describes an HCCC in the lung of a 54-year-old female patient. Methods: We summarize the histomorphologic, immunophenotypic, and molecular features for our and three previously reported HCCCs of the lung with emphasis on potential diagnostic pitfalls. Results: Sections of a well-circumscribed 3.5-cm lung mass were characterized by a bronchocentric tumor growing in sheets, nests, and cords in a background of hyalinized stroma...
July 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28799138/treatment-deintensification-for-human-papillomavirus-associated-oropharyngeal-cancer
#6
EDITORIAL
Demetri Arnaoutakis, Baran D Sumer
No abstract text is available yet for this article.
November 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28795434/concomitant-antegrade-stent-grafting-of-the-descending-thoracic-aorta-during-transverse-hemiarch-reconstruction-for-acute-debakey-i-aortic-dissection-repair-improves-aortic-remodeling
#7
Ibrahim Sultan, Tyler J Wallen, Andreas Habertheuer, Mary Siki, George J Arnaoutakis, Joseph Bavaria, Wilson Y Szeto, Rita Milewski, Prashanth Vallabhajosyula
BACKGROUND AND AIM: Concomitant endovascular stent grafting of the descending thoracic aorta during open repair for acute DeBakey I aortic dissection can be performed in patients with extensive dissection and malperfusion. We analyzed the effects of this strategy on distal aortic remodeling. METHODS: From 2006-2014, acute DeBakey I dissection patients without primary aortic arch tear undergoing open distal hemiarch reconstruction (Standard group) versus those undergoing hemiarch with descending thoracic aorta (DTA) thoracic endovascular aortic repair (TEVAR group) were retrospectively reviewed...
August 9, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28760582/improved-outcomes-with-proximal-radial-cephalic-arteriovenous-fistulas-compared-with-brachial-cephalic-arteriovenous-fistulas
#8
COMPARATIVE STUDY
Dean J Arnaoutakis, Elise P Deroo, Patrick McGlynn, Maxwell D Coll, Michael Belkin, Dirk M Hentschel, C Keith Ozaki
BACKGROUND: Brachial-cephalic arteriovenous fistulas (BCFs) are associated with high-flow volumes, leading to potential risks such as arm swelling, steal syndrome, pseudoaneurysm (due to a pressurized access), and cephalic arch stenosis. We hypothesized that a proximal radial-cephalic fistula (prRCF) configuration mitigates these risks because a lower flow state is created. Furthermore, we also hypothesized that despite these lower flows, patencies (primary, primary assisted, secondary) are sustained...
November 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28730725/targeting-nano-drug-delivery-to-cancer-cells-using-tunable-multi-layer-silver-decorated-gold-nanorods
#9
Zeid A Nima, Ahmed M Alwbari, Vijayalakshmi Dantuluri, Rabab N Hamzah, Natasha Sra, Pooja Motwani, Konstantinos Arnaoutakis, Rebecca A Levy, Amani F Bohliqa, Dmitry Nedosekin, Vladimir P Zharov, Issam Makhoul, Alexandru S Biris
Multifunctional nanoparticles have high potential as targeting delivery vehicles for cancer chemotherapy. In this study, silver-decorated gold nanorods (AuNR\Ag) have been successfully used to deliver specific, targeted chemotherapy against breast cancer (MCF7) and prostate carcinoma (PC3) cell lines. Doxorubicin, a commonly used chemotherapy, and anti-Epithelial cell adhesion molecule (anti-EpCAM) antibodies were covalently bonded to thiolated polyethylene glycol-coated AuNR\Ag, and the resultant system was used to deliver the drugs to cancer cells in vitro...
July 21, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28648536/outcomes-of-elective-aortic-hemiarch-reconstruction-for-aneurysmal-disease-in-the-elderly
#10
COMPARATIVE STUDY
Arman Kilic, George J Arnaoutakis, Joseph E Bavaria, Ibrahim Sultan, Nimesh D Desai, Prashanth Vallabhajosyula, Matthew L Williams, Rita K Milewski, Wilson Y Szeto
BACKGROUND: This study evaluated outcomes of elective aortic hemiarch reconstruction for aneurysmal disease in the elderly. METHODS: Patients undergoing elective aortic hemiarch reconstruction for aneurysmal disease at a single institution between 2009 and 2014 were retrospectively reviewed. Patients were stratified into nonelderly (aged less than 75 years) versus elderly (aged 75 years or more). Outcomes included operative mortality and morbidity. RESULTS: In all, 629 patients (95 elderly; 15%) were included...
November 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28585463/endoscopic-lateral-cartilage-graft-tympanoplasty
#11
Cameron C Wick, Demetri Arnaoutakis, Vivian F Kaul, Brandon Isaacson
Objective To describe a novel technique for lateral graft tympanoplasty. Study Design Case series with chart review. Setting Tertiary care university hospital. Subjects and Methods Pediatric and adult patients with tympanic membrane perforations deemed unfavorable for a medial graft technique due to the perforation characteristics or myringitis. Results Between 2014 and 2016, 34 ears from 31 patients underwent a transcanal endoscopic lateral cartilage graft tympanoplasty. The mean age was 24.4 years (range, 6-71 years), and 22 patients (65%) were younger than 18 years...
October 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28410640/florida-sleeve-procedure-is-durable-and-improves-aortic-valve-function-in-marfan-syndrome-patients
#12
Seyed Hossein Aalaei-Andabili, Tomas Martin, Philip Hess, Charles Klodell, Ashkan Karimi, George Arnaoutakis, Teng Lee, Thomas Beaver
BACKGROUND: The Florida sleeve (FS) procedure was developed as a simplified approach for repair of functional type I aortic insufficiency secondary to aortic root aneurysm. We evaluated postoperative aortic valve function, long-term survival, and freedom from reoperation in Marfan syndrome patients who underwent the FS procedure at our center. METHODS: All Marfan syndrome patients undergoing FS procedure from May 2002 to December 2014 were included. Echocardiography assessment included left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), ejection fraction, and degree of aortic insufficiency (none = 0, minimal = 1, mild = 2, moderate = 3, severe = 4)...
September 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28395872/outcomes-of-antegrade-stent-graft-deployment-during-hybrid-aortic-arch-repair
#13
Seyed Hossein Aalaei-Andabili, Salvatore Scali, Charles Klodell, Teng Lee, Philip Hess, Tomas Martin, Adam Beck, Robert Feezor, Mahmoud Alhussaini, George Arnaoutakis, Thomas Beaver
BACKGROUND: Complex aortic arch disease can be a formidable challenge and is often treated with a two-stage elephant trunk technique. We examined our experience with hybrid arch repair with combined zone 0 stent graft deployment. METHODS: A retrospective review was conducted of all patients who underwent type 2 hybrid arch replacement and zone 0 antegrade endovascular stent graft deployments at a single university center from June 2010 to August 2015. RESULTS: The review included 48 patients, 25 (52%) elective and 23 (48%) nonelective, with a mean ± SD age of 64 ± 11 years...
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28329296/extension-of-a-stanford-type-a-aortic-dissection-into-the-feeding-vessel-of-a-pulmonary-sequestration
#14
Mary A Siki, Ibrahim Sultan, George J Arnaoutakis, Nimesh D Desai
No abstract text is available yet for this article.
August 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28259578/impact-of-body-mass-index-and-gender-on-wound-complications-after-lower-extremity-arterial-surgery
#15
COMPARATIVE STUDY
Dean J Arnaoutakis, Rebecca E Scully, Gaurav Sharma, Samir K Shah, C Keith Ozaki, Michael Belkin, Louis L Nguyen
OBJECTIVE: Wound complications (WCs) after lower extremity arterial surgery (LEAS) are common, resulting in readmissions and reinterventions. Whereas diabetes and obesity are known risk factors for WCs, gender-specific variability in body fat distribution (android vs gynoid) may drive differential risks of WCs after LEAS. We analyzed the independent and synergistic effects of gender and body mass index (BMI) on WCs. METHODS: We performed a retrospective review of prospectively collected data from a published, randomized, multicenter trial assessing the incidence of WCs (dehiscence, surgical site infections, seroma, and hematoma) after LEAS...
June 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27892990/zika-virus-what-the-otolaryngologist-should-know-a-review
#16
REVIEW
Demetri Arnaoutakis, Tapan Padhya
Importance: Initially discovered in 1947, Zika virus infection received little notoriety as a tropical disease until 2015 when an outbreak of microcephaly cases was reported in Brazil. Zika is a single-stranded RNA arbovirus of the Flaviviridae family. The primary source of infection in humans stems from Aedes aegypti mosquito bites but can also occur through sexual, blood, and perinatal transmission. With expectations that 3 to 4 million people across the Americas will be infected over the next year, the World Health Organization has declared this event a Public Health Emergency of International Concern...
January 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27658897/systematic-identification-and-management-of-barriers-to-vascular-surgery-patient-discharge-time-of-day
#17
Gaurav Sharma, Danny Wong, Dean J Arnaoutakis, Samir K Shah, Alice O'Brien, Stanley W Ashley, C Keith Ozaki
OBJECTIVE: Length of stay fails to completely capture the clinical and economic effects of patient progression through the phases of inpatient care, such as admission, room placement, procedures, and discharge. Delayed hospital throughput has been linked to increased time spent in the emergency department and postanesthesia care unit, delayed time to treatment, increased in-hospital mortality, decreased patient satisfaction, and lost hospital revenue. We identified barriers to vascular surgery inpatient care progression and instituted defined measures to positively impact standardized metrics...
January 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27650343/endovascular-repair-of-abdominal-aortic-aneurysms
#18
REVIEW
Dean J Arnaoutakis, Martin Zammert, Alan Karthikesalingam, Michael Belkin
Endovascular repair of abdominal aortic aneurysms is an important technique in the vascular surgeon's armamentarium, which has created a seismic shift in the management of aortic pathology over the past two decades. In comparison to traditional open repair, the endovascular approach is associated with significantly improved perioperative morbidity and mortality. The early survival benefit of endovascular abdominal aortic aneurysm repair is sustained up to 3 years postoperatively, but longer-term life expectancy remains poor regardless of operative modality...
September 2016: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/27649996/the-future-is-now-an-endovascular-option-for-type-a-aortic-dissection
#19
EDITORIAL
George J Arnaoutakis, Wilson Y Szeto
No abstract text is available yet for this article.
February 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27516202/integrating-collaborative-learning-and-competition-in-a-hematology-oncology-training-program
#20
Issam Makhoul, Pooja Motwani, Liudmila Schafer, Konstantinos Arnaoutakis, Fade Mahmoud, Mazin Safar, Dorothy Graves, Paulette Mehta, Rang Govindarajan, Laura Hutchins, Carol Thrush
New educational methods and structures to improve medical education are needed to face the challenge of an exponential increase and complexity of medical knowledge. Collaborative learning has been increasingly used in education, but its use in medical training programs is in its infancy, and its impact is still unknown; the role of competition in education is more controversial. We introduced these pedagogical methods to the hematology/oncology fellowship program at the University of Arkansas for Medical Sciences to improve attendance and performance at didactic activities and different educational outcomes...
August 12, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
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