keyword
MENU ▼
Read by QxMD icon Read
search

Mahmoud

keyword
https://www.readbyqxmd.com/read/28822817/rosiglitazone-promotes-cardiac-hypertrophy-and-alters-chromatin-remodeling-in-isolated-cardiomyocytes
#1
Lama Fawaz Pharaon, Naglaa Fathi El-Orabi, Muhammad Kunhi, Nadya Al Yacoub, Salma Mahmoud Awad, Coralie Poizat
Rosiglitazone is an anti-diabetic agent that raised a major controversy over its cardiovascular adverse effects. There is in vivo evidence that Rosiglitazone promotes cardiac hypertrophy by PPAR -γ-independent mechanisms. However, whether Rosiglitazone directly alters hypertrophic growth in cardiac cells is unknown. Chromatin remodeling by histone post-translational modifications has emerged as critical for many cardiomyopathies. Based on these observations, this study was initiated to investigate the cardiac hypertrophic effect of Rosiglitazone in a cellular model of primary neonatal rat cardiomyocytes (NRCM)...
August 16, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28822668/intrinsic-wave-propagation-of-myocardial-stretch-a-new-tool-to-evaluate-myocardial-stiffness-a-pilot-study-in-patients-with-aortic-stenosis-and-mitral-regurgitation
#2
Cristina Pislaru, Mahmoud M Alashry, Jeremy J Thaden, Patricia A Pellikka, Maurice Enriquez-Sarano, Sorin V Pislaru
BACKGROUND: Left ventricular (LV) filling following atrial contraction generates LV myocardial stretch that propagates from base to apex with a speed proportional to myocardial elasticity. The aim of this study was to test the hypothesis that intrinsic velocity propagation of myocardial stretch (iVP) would be altered in patients with valvular disease and chronic LV pressure overload or volume overload, which may adversely affect mechanical properties of the LV tissue. A second aim was to compare iVP with flow propagation velocity in the chamber...
August 16, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28822564/regenerative-endodontic-treatment-or-mineral-trioxide-aggregate-apical-plug-in-teeth-with-necrotic-pulps-and-open-apices-a-systematic-review-and-meta-analysis
#3
REVIEW
Mahmoud Torabinejad, Ali Nosrat, Prashant Verma, Oyoyo Udochukwu
INTRODUCTION: A mineral trioxide aggregate (MTA) apical plug (MAP) and regenerative endodontic treatment (RET) have shown acceptable clinical outcomes. However, comparative studies are scarce. The aims of this study were to examine the level of evidence for both treatments, conduct a systematic review of the literature on MAP and RET, and run a meta-analysis on the survival and success rates of teeth treated with these procedures. METHODS: Electronic searches were performed in MEDLINE, Web of Science, and the Cochrane Library...
August 16, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28821026/ultrahigh-antibacterial-efficacy-of-meropenem-loaded-chitosan-nanoparticles-in-a-septic-animal-model
#4
Ayat Abdelkader, Mohamed A El-Mokhtar, Ola Abdelkader, Mostafa A Hamad, Mahmoud Elsabahy, Omaima N El-Gazayerly
Antimicrobial resistance is one of the most significant health challenges worldwide. Meropenem is a broad spectrum beta-lactam antibiotic that possesses high activity against Gram-positive and Gram-negative bacteria. However, it has a short plasma half-life, and thus requiring frequent administration of high doses. For the first time, meropenem-loaded chitosan nanoparticles were prepared and evaluated as a potential tool to overcome antimicrobial resistance and to improve pharmacokinetics of the drug. Spherical nanosized particles were prepared and demonstrated ultrahigh encapsulation efficiency of meropenem (i...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820882/correlation-between-mosquito-larval-density-and-their-habitat-physicochemical-characteristics-in-mazandaran-province-northern-iran
#5
Seyed Hassan Nikookar, Mahmoud Fazeli-Dinan, Shahyad Azari-Hamidian, Seyed Nouraddin Mousavinasab, Mohsen Aarabi, Seyyed Payman Ziapour, Yahya Esfandyari, Ahmadali Enayati
Characteristics of mosquito larval habitats are important in determining whether they can survive and successfully complete their developmental stages. Therefore, data on the ecological factors affecting mosquito density and abundance especially the physicochemical properties of water of their breeding sites, can possibly be helpful in implementing larval management programs. Mosquito larvae were collected using a standard 350 ml dipper from fixed habitats including: artificial pool, river edge, creek and etc, in 30 villages of 16 counties from May-December 2014...
August 18, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28818869/clinical-risks-and-healthcare-utilization-of-haematopoietic-cell-transplantation-for-sickle-cell-disease-in-the-u-s-using-merged-databases
#6
Staci D Arnold, Ruta Brazauskas, Naya He, Yimei Li, Richard Aplenc, Zhezhen Jin, Matt Hall, Yoshiko Atsuta, Jignesh Dalal, Theresa Hahn, Nandita Khera, Carmem Bonfim, Navneet S Majhail, Miguel Angel Diaz, Cesar O Freytes, William A Wood, Bipin M Savani, Rammurti T Kamble, Susan Parsons, Ibrahim Ahmed, Keith Sullivan, Sara Beattie, Christopher Dandoy, Reinhold Munker, Susana Marino, Menachem Bitan, Hisham Abdel-Azim, Mahmoud Aljurf, Richard F Olsson, Sarita Joshi, Dave Buchbinder, Michael J Eckrich, Shahrukh Hashmi, Hillard Lazarus, David I Marks, Amir Steinberg, Ayman Saad, Usama Gergis, Lakshmanan Krishnamurti, Allistair Abraham, Hemalatha G Rangarajan, Mark Walters, Joseph Lipscomb, Wael Saber, Prakash Satwani
Allogeneic hematopoietic cell transplant advances for sickle cell disease improve outcomes, but limited healthcare utilization analysis exists. We hypothesized that early transplant (age < 10 years) improves outcomes and decreases healthcare utilization compared to late. We performed a retrospective study of US children transplanted for sickle cell during 2000-2013 using two large databases. Univariate and Cox models estimated associations between demographics, sickle cell severity, and transplant-related variables on mortality and chronic graft versus-host-disease; while, Wilcoxon, Kruskal-Wallis, or linear trend tests estimated against healthcare utilization...
August 17, 2017: Haematologica
https://www.readbyqxmd.com/read/28816705/microvascular-vasodilator-plasticity-following-acute-exercise
#7
Austin T Robinson, Ibra S Fancher, Abeer M Mahmoud, Shane A Phillips
Endothelium-dependent vasodilation is reduced following acute exercise, or following high intraluminal pressure in isolated arterioles from sedentary adults, but not in arterioles from regular exercisers. The preserved vasodilation in arterioles from exercisers is hydrogen peroxide (H2O2)-dependent, whereas resting dilation is nitric oxide (NO)-dependent. We hypothesize chronic exercise elicits adaptations allowing for maintained vasodilation when NO bioavailability is reduced.
August 14, 2017: Exercise and Sport Sciences Reviews
https://www.readbyqxmd.com/read/28815420/road-map-for-the-structure-based-design-of-selective-covalent-hcv-ns3-4a-protease-inhibitors
#8
REVIEW
Letitia Shunmugam, Pritika Ramharack, Mahmoud E S Soliman
Over the last 2 decades, covalent inhibitors have gained much popularity and is living up to its reputation as a powerful tool in drug discovery. Covalent inhibitors possess many significant advantages including increased biochemical efficiency, prolonged duration and the ability to target shallow, solvent exposed substrate-binding domains. However, rapidly mounting concerns over the potential toxicity, highly reactive nature and general lack of selectivity have negatively impacted covalent inhibitor development...
August 16, 2017: Protein Journal
https://www.readbyqxmd.com/read/28814372/association-of-cyp19a1-gene-polymorphisms-with-anoestrus-in-water-buffaloes
#9
Khairy M El-Bayomi, Ayman A Saleh, Ashraf Awad, Mahmoud S El-Tarabany, Hadeel S El-Qaliouby, Mohamed Afifi, Shymaa El-Komy, Walaa M Essawi, Essam A Almadaly, Mohammed A El-Magd
Cytochrome P450 aromatase (encoded by the CYP19A1 gene) regulates oestrogen biosynthesis and so plays an essential role in female fertility. We investigated the genetic association of CYP19A1 with the risk of anoestrus in Egyptian water buffaloes. A total of 651 animals (326 anoestrous and 325 cycling) were used in this case-control study. Using single-strand conformation polymorphisms and sequencing, four single nucleotide polymorphisms (SNPs) were detected; c.-135T>C SNP in the 5'UTR and three non-synonymous SNPs: c...
August 17, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28811935/pars-plana-vitrectomy-with-internal-limiting-membrane-peeling-in-traumatic-macular-hole-14-perfluoropropane-c3f8-versus-silicone-oil-tamponade
#10
Ashraf Bor'i, Mahmoud A Al-Aswad, Ahmed Abdelwahab Saad, Dina Hamada, Ashraf Mahrous
PURPOSE: To evaluate the outcome of 23 G PPV and ILM peeling with 14% C3F8 compared with silicone oil tamponade in cases of TMHs without spontaneous closure. METHODS: A retrospective comparative study included 33 eyes with TMHs; 7 eyes healed spontaneously, and the remaining 26 eyes have been treated with PPV and ILM peeling. Silicone oil was used as a tamponade for children or adults who refused to adopt face-down position (10 cases). In all other cases (16 cases), 14% C3F8 was used...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28811820/modified-mahalanobis-taguchi-system-for-imbalance-data-classification
#11
Mahmoud El-Banna
The Mahalanobis Taguchi System (MTS) is considered one of the most promising binary classification algorithms to handle imbalance data. Unfortunately, MTS lacks a method for determining an efficient threshold for the binary classification. In this paper, a nonlinear optimization model is formulated based on minimizing the distance between MTS Receiver Operating Characteristics (ROC) curve and the theoretical optimal point named Modified Mahalanobis Taguchi System (MMTS). To validate the MMTS classification efficacy, it has been benchmarked with Support Vector Machines (SVMs), Naive Bayes (NB), Probabilistic Mahalanobis Taguchi Systems (PTM), Synthetic Minority Oversampling Technique (SMOTE), Adaptive Conformal Transformation (ACT), Kernel Boundary Alignment (KBA), Hidden Naive Bayes (HNB), and other improved Naive Bayes algorithms...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28811657/colorimetric-fingerprints-of-gold-nanorods-for-discriminating-catecholamine-neurotransmitters-in-urine-samples
#12
Somayeh Jafarinejad, Mahmoud Ghazi-Khansari, Forough Ghasemi, Pezhman Sasanpour, M Reza Hormozi-Nezhad
Catecholamine neurotransmitters, generally including dopamine (DA), epinephrine (EP) and norepinephrine (NE) are known as substantial indicators of various neurological diseases. Simultaneous detection of these compounds and their metabolites is highly recommended in early clinical diagnosis. To this aim, in the present contribution, a high performance colorimetric sensor array has been proposed for the detection and discrimination of catecholamines based on their reducing ability to deposit silver on the surface of gold nanorods (AuNRs)...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28811566/injectable-phosphorescence-based-oxygen-biosensors-identify-post-ischemic-reactive-hyperoxia
#13
Jennifer S Chien, Mahmoud Mohammed, Hysem Eldik, Mohamed M Ibrahim, Jeremy Martinez, Scott P Nichols, Natalie Wisniewski, Bruce Klitzman
Novel injectable biosensors were used to measure interstitial oxygenation before, during, and after transient ischemia. It is well known that reactive hyperemia occurs following a period of ischemia. However, increased blood flow does not necessarily mean increased oxygen tension in the tissue. Therefore, the purpose of this study was to test the hypothesis that tissue reactive hyperoxia occurs following release of hind-limb tourniquet occlusions. Rats were injected with bilateral hind-limb biosensors and were simultaneously subjected to a unilateral femoral vessel ligation...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28808820/benzene-contaminated-groundwater-remediation-using-calcium-peroxide-nanoparticles-synthesis-and-process-optimization
#14
Hamid Mosmeri, Ebrahim Alaie, Mahmoud Shavandi, Seyed Mohammad Mehdi Dastgheib, Saeideh Tasharrofi
Nano-size calcium peroxide (nCaO2) is an appropriate oxygen source which can meet the needs of in situ chemical oxidation (ISCO) for contaminant remediation from groundwater. In the present study, an easy to handle procedure for synthesis of CaO2 nanoparticles has been investigated. Modeling and optimization of synthesis process was performed by application of response surface methodology (RSM) and central composite rotatable design (CCRD) method. Synthesized nanoparticles were characterized by XRD and FESEM techniques...
August 14, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28808795/cerebral-venous-thrombosis-continental-disparities
#15
Laith Maali, Sheema Khan, Fares Qeadan, Mahmoud Ismail, Davana Ramaswamy, Vishnumurthy S Hedna
Cerebral venous thrombosis (CVT) usually accounts for < 1% of all strokes. Global disparity and diversity in their demographics, etiology, clinical features, radiological presentation, and mortality have not been previously explored. A systematic search was performed for publications in PubMed using key words "cerebral venous thrombosis," "Cerebral vein thrombosis," and "Cortical vein Thrombosis." A total of 600 relevant studies were abstracted with strict selection criteria, and a total of 7048 patient's data were used for the final analysis...
August 14, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28808648/traumatic-arteriovenous-malformation-of-the-superficial-temporal-artery
#16
Mahmoud Omrani Fard, Omid Yousofnejad, Mohammadbagher Heydari
Most of the vascular lesions on head and neck soft tissue are congenital, but a rare cause can be trauma. A 23-year-old man came to our clinic with a wide pulsatile tortuous mass in the left temporofrontal area. That mass was appeared since 10 years ago. Ten years before his coming to our clinic, he had a blunt trauma in that area. After that, a small wound appeared there and healed gradually. In clinical examination, mass was large and pulsatile, and a fine murmur was detected from it. In paraclinical examination, computed tomography scan with intravenous contrast and sonography revealed a vascular mass with arteriovenous (AV) fistula in soft tissue only in that area...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28808586/quality-of-vision-after-deep-anterior-lamellar-keratoplasty-fluid-dissection-compared-to-penetrating-keratoplasty-for-the-treatment-of-keratoconus
#17
Islam Mahmoud Hamdi, Momen Mahmoud Hamdi
PURPOSE: To compare the visual quality of patients with keratoconus who underwent penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK) with fluid dissection. DESIGN: Cross-sectional, observational study. METHODS: Twelve eyes that underwent PKP (PKP group) were compared to 24 eyes that underwent DALK (DALK group) after complete removal of sutures and stability of refraction. Visual, refractive, corneal topographic, corneal aberrometry, and ocular aberrometry parameters were compared for both groups...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28808363/incidence-characteristics-and-survival-trend-of-cardiopulmonary-resuscitation-following-in-hospital-compared-to-out-of-hospital-cardiac-arrest-in-northern-jordan
#18
Liqaa A Raffee, Shaher M Samrah, Hani Najih Al Yousef, Mahmoud Abu Abeeleh, Khaled Z Alawneh
BACKGROUND: Cardiac arrest remains a leading cause of mortality worldwide. Early cardiopulmonary resuscitation (CPR) is the cornerstone intervention to optimize the survival rates. OBJECTIVES: The main aim of this study was to determine and compare the incidence, characteristics, risk factors, and outcomes of CPR in a referral university hospital following in-hospital cardiac arrests (IHCAs) and out-of-hospital cardiac arrest (OHCA) in Northern Jordan. PATIENTS AND METHODS: Retrospective observational study of adults referred to King Abdulla University Hospital who received CPR between January 2014 and January 2015...
July 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28808176/teaching-video-neuroimages-trapezius-muscle-hypertrophy-in-multifocal-motor-neuropathy
#19
Pierre R Bourque, Mahmoud Al-Hajji, Jocelyn Zwicker, Jodi Warman Chardon
No abstract text is available yet for this article.
August 15, 2017: Neurology
https://www.readbyqxmd.com/read/28806424/geometric-evaluation-of-the-effect-of-prosthetic-rehabilitation-on-the-facial-appearance-of-mandibulectomy-patients-a-preliminary-study
#20
Amel M Aswehlee, Mahmoud E Elbashti, Mariko Hattori, Yuka I Sumita, Hisashi Taniguchi
PURPOSE: The purpose of this study was to geometrically evaluate the effect of prosthetic rehabilitation on the facial appearance of mandibulectomy patients. MATERIALS AND METHODS: Facial scans (with and without prostheses) were performed for 16 mandibulectomy patients using a noncontact three-dimensional (3D) digitizer, and 3D images were reconstructed with the corresponding software. The 3D datasets were geometrically evaluated and compared using 3D evaluation software...
August 14, 2017: International Journal of Prosthodontics
keyword
keyword
120306
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"