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JOURNAL ARTICLE
Kanishk Kaushik, Anna M de Kort, Rosemarie van Dort, Reinier G J van der Zwet, Bob Siegerink, Sabine Voigt, Erik W van Zwet, Maaike C van der Plas, Emma A Koemans, Ingeborg Rasing, Roy P C Kessels, Huub A M Middelkoop, Floris H B M Schreuder, Catharina J M Klijn, Marcel M Verbeek, Gisela M Terwindt, Ellis S van Etten, Marieke J H Wermer
BACKGROUND: Neuropsychiatric symptoms (NPS) may affect cognition, but their burden in cerebral amyloid angiopathy (CAA), one of the main causes of intracerebral hemorrhage (ICH) and dementia in the elderly, remains unclear. We investigated NPS, with emphasis on apathy and irritability in sporadic (sCAA) and Dutch-type hereditary (D-)CAA. METHODS: We included patients with sCAA and (pre)symptomatic D-CAA, and controls from four prospective cohort studies. We assessed NPS per group, stratified for history of ICH, using the informant-based Neuropsychiatric Inventory (NPI-Q), Starkstein Apathy scale (SAS), and Irritability Scale...
April 6, 2024: Alzheimer's Research & Therapy
#2
JOURNAL ARTICLE
Melissa T Baysari, Bethany Annemarie Van Dort, Kristian Stanceski, Andrew Hargreaves, Wu Yi Zheng, Maria Moran, Richard O Day, Ling Li, Johanna Westbrook, Sarah N Hilmer
OBJECTIVE: To identify barriers to hospital participation in controlled cluster trials of clinical decision support (CDS) and potential strategies for addressing barriers. DESIGN: Qualitative descriptive design comprising semistructured interviews. SETTING: Five hospitals in New South Wales and one hospital in Queensland, Australia. PARTICIPANTS: Senior hospital staff, including department directors, chief information officers and those working in health informatics teams...
March 12, 2024: BMJ Open
#3
JOURNAL ARTICLE
Ling Li, Jannah Baker, Renee Quirk, Danielle Deidun, Maria Moran, Ahmed Abo Salem, Nanda Aryal, Bethany A Van Dort, Wu Yi Zheng, Andrew Hargreaves, Paula Doherty, Sarah N Hilmer, Richard O Day, Johanna I Westbrook, Melissa T Baysari
INTRODUCTION: Drug-drug interactions (DDIs) have potential to cause patient harm, including lowering therapeutic efficacy. This study aimed to (i) determine the prevalence of potential DDIs (pDDIs); clinically relevant DDIs (cDDIs), that is, DDIs that could lead to patient harm, taking into account a patient's individual clinical profile, drug effects and severity of potential harmful outcome; and subsequent actual harm among hospitalized patients and (ii) examine the impact of transitioning from paper-based medication charts to electronic medication management (eMM) on DDIs and patient harms...
March 13, 2024: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
#4
JOURNAL ARTICLE
Sensitivity of the Boston Criteria Version 2.0 in Dutch-Type Hereditary Cerebral Amyloid Angiopathy.
Reinier van der Zwet, Emma Koemans, Sabine Voigt, Rosemarie van Dort, Ingeborg Rasing, Kanishk Kaushik, Thijs van Harten, Manon Schipper, Gisela M Terwindt, Thijs van Osch, Marianne Aa van Walderveen, Ellis van Etten, Marieke Wermer
BACKGROUND AND AIM: The revised Boston criteria v2.0 for cerebral amyloid angiopathy (CAA) add two radiological markers to the existing criteria: severe visible perivascular spaces in the centrum semiovale and white matter hyperintensities (WMH) in a multispot pattern. This study aims to determine the sensitivity of the updated criteria in mutation carriers with Dutch-type hereditary CAA (D-CAA) in an early and later disease stage. METHODS: In this cross-sectional study, we included presymptomatic and symptomatic D-CAA mutation carriers from our prospective natural history study (AURORA) at the Leiden University Medical Center between 2018 and 2021...
March 6, 2024: International Journal of Stroke: Official Journal of the International Stroke Society
#5
JOURNAL ARTICLE
Kaaren Mathias, Noah Bunkley, Pooja Pillai, Kenneth A Ae-Ngibise, Lily Kpobi, Dan Taylor, Kaustubh Joag, Meenal Rawat, Weeam Hammoudeh, Suzan Mitwalli, Ashraf Kagee, Andre van Rensburg, Dörte Bemme, Rochelle A Burgess, Sumeet Jain, Hanna Kienzler, Ursula M Read
Global mental health [GMH] scholarship and practice has typically focused on the unmet needs and barriers to mental health in communities, developing biomedical and psychosocial interventions for integration into formal health care platforms in response. In this article, we analyse four diverse settings to disrupt the emphasises on health system weaknesses, treatment gaps and barriers which can perpetuate harmful hierarchies and colonial and medical assumptions, or a 'deficit model'. We draw on the experiential knowledge of community mental health practitioners and researchers working in Ghana, India, the Occupied Palestinian Territory and South Africa to describe key assets existing in 'informal' community mental health care systems and how these are shaped by socio-political contexts...
2024: PLOS Glob Public Health
#6
JOURNAL ARTICLE
Borja Ferrero-Bordera, Jürgen Bartel, Jan Maarten van Dijl, Dörte Becher, Sandra Maaß
Understanding cellular mechanisms of stress management relies on omics data as a valuable resource. However, the lack of absolute quantitative data on protein abundances remains a significant limitation, particularly when comparing protein abundances across different cell compartments. In this study, we aimed to gain deeper insights into the proteomic responses of the Gram-positive model bacterium Bacillus subtilis to disulfide stress. We determined proteome-wide absolute abundances, focusing on different sub-cellular locations (cytosol and membrane) as well as the extracellular medium, and combined these data with redox state determination...
February 15, 2024: Microbiology Spectrum
#7
JOURNAL ARTICLE
Yinghan Zhu, Norihide Maikusa, Joaquim Radua, Philipp G Sämann, Paolo Fusar-Poli, Ingrid Agartz, Ole A Andreassen, Peter Bachman, Inmaculada Baeza, Xiaogang Chen, Sunah Choi, Cheryl M Corcoran, Bjørn H Ebdrup, Adriana Fortea, Ranjini Rg Garani, Birte Yding Glenthøj, Louise Birkedal Glenthøj, Shalaila S Haas, Holly K Hamilton, Rebecca A Hayes, Ying He, Karsten Heekeren, Kiyoto Kasai, Naoyuki Katagiri, Minah Kim, Tina D Kristensen, Jun Soo Kwon, Stephen M Lawrie, Irina Lebedeva, Jimmy Lee, Rachel L Loewy, Daniel H Mathalon, Philip McGuire, Romina Mizrahi, Masafumi Mizuno, Paul Møller, Takahiro Nemoto, Dorte Nordholm, Maria A Omelchenko, Jayachandra M Raghava, Jan I Røssberg, Wulf Rössler, Dean F Salisbury, Daiki Sasabayashi, Lukasz Smigielski, Gisela Sugranyes, Tsutomu Takahashi, Christian K Tamnes, Jinsong Tang, Anastasia Theodoridou, Alexander S Tomyshev, Peter J Uhlhaas, Tor G Værnes, Therese A M J van Amelsvoort, James A Waltz, Lars T Westlye, Juan H Zhou, Paul M Thompson, Dennis Hernaus, Maria Jalbrzikowski, Shinsuke Koike
Machine learning approaches using structural magnetic resonance imaging (sMRI) can be informative for disease classification, although their ability to predict psychosis is largely unknown. We created a model with individuals at CHR who developed psychosis later (CHR-PS+) from healthy controls (HCs) that can differentiate each other. We also evaluated whether we could distinguish CHR-PS+ individuals from those who did not develop psychosis later (CHR-PS-) and those with uncertain follow-up status (CHR-UNK)...
February 9, 2024: Molecular Psychiatry
#8
JOURNAL ARTICLE
Bethany A Van Dort, Angus Ritchie, Jonathan Penm, Timothy J Gray, Amrita Ronnachit, Melissa T Baysari
AIMS: We aim to examine and understand the work processes of antimicrobial stewardship (AMS) teams across 2 hospitals that use the same digital intervention, and to identify the barriers and enablers to effective AMS in each setting. METHODS: Employing a contextual inquiry approach informed by the Systems Engineering Initiative for Patient Safety (SEIPS) model, observations and semistructured interviews were conducted with AMS team members (n = 15) in 2 Australian hospitals...
January 31, 2024: British Journal of Clinical Pharmacology
#9
JOURNAL ARTICLE
Colin J McMahon, Inga Voges, Petra Jenkins, Margarita Brida, Annemien E van der Bosch, Mikael Dellborg, Ruth Heying, Jörg I Stein, Borislav Georgiev, Senka Mesihovic-Dinarevic, Katja Prokšelj, Gylfi Oskarsson, Alexandra Frogoudaki, Tevfik Karagöz, Antonis Jossif, Gabriela Doros, Dorte Nielsen, Mikko Jalanko, Inmaculada Sanchez Perez, Sílvia Alvares, Mette-Elise Estensen, Andreas Petropoulos, Raili Tagen, Lina Gumbienė, Ina Michel-Behnke, Peter Olejnik, Paul F Clift, Skaiste Sendzikaite, Dimpna C Albert-Brotons, Mark Rhodes, Olli Pitkänen, Pier Paolo Bassareo, Michael A Gatzoulis, Kevin Walsh, Ornella Milanesi, Magalie Ladouceur, Massimo Chessa, Werner Budts
OBJECTIVES: This study aimed to determine the status of training of adult congenital heart disease (ACHD) cardiologists in Europe. METHODS: A questionnaire was sent to ACHD cardiologists from 34 European countries. RESULTS: Representatives from 31 of 34 countries (91%) responded. ACHD cardiology was recognised by the respective ministry of Health in two countries (7%) as a subspecialty. Two countries (7%) have formally recognised ACHD training programmes, 15 (48%) have informal (neither accredited nor certified) training and 14 (45%) have very limited or no programme...
December 14, 2023: Open Heart
#10
JOURNAL ARTICLE
Tobias Schilling, Borja Ferrero-Bordera, Jolanda Neef, Sandra Maaβ, Dörte Becher, Jan Maarten van Dijl
Bacillus subtilis is a major workhorse for enzyme production in industrially relevant quantities. Compared to mammalian-based expression systems, B. subtilis presents intrinsic advantages, such as high growth rates, high space-time yield, unique protein secretion capabilities, and low maintenance costs. However, B. subtilis shows clear limitations in the production of biopharmaceuticals, especially proteins from eukaryotic origin that contain multiple disulfide bonds. In the present study, we deployed genome minimization, signal peptide screening, and coexpression of recombinant thiol oxidases as strategies to improve the ability of B...
November 27, 2023: ACS Synthetic Biology
#11
JOURNAL ARTICLE
I Adachi, K Adamczyk, L Aggarwal, H Aihara, N Akopov, A Aloisio, N Anh Ky, D M Asner, H Atmacan, T Aushev, V Aushev, M Aversano, V Babu, H Bae, S Bahinipati, P Bambade, Sw Banerjee, M Barrett, J Baudot, M Bauer, A Baur, A Beaubien, F Becherer, J Becker, P K Behera, J V Bennett, F U Bernlochner, V Bertacchi, M Bertemes, E Bertholet, M Bessner, S Bettarini, B Bhuyan, F Bianchi, T Bilka, D Biswas, A Bobrov, D Bodrov, A Bolz, A Bondar, J Borah, A Bozek, M Bračko, P Branchini, R A Briere, T E Browder, A Budano, S Bussino, M Campajola, L Cao, G Casarosa, C Cecchi, J Cerasoli, M-C Chang, P Chang, R Cheaib, P Cheema, V Chekelian, B G Cheon, K Chilikin, K Chirapatpimol, H-E Cho, K Cho, S-K Choi, S Choudhury, J Cochran, L Corona, L M Cremaldi, S Das, F Dattola, E De La Cruz-Burelo, S A De La Motte, G De Nardo, M De Nuccio, G De Pietro, R de Sangro, M Destefanis, S Dey, R Dhamija, A Di Canto, F Di Capua, J Dingfelder, Z Doležal, I Domínguez Jiménez, T V Dong, M Dorigo, K Dort, D Dossett, S Dreyer, S Dubey, G Dujany, P Ecker, M Eliachevitch, D Epifanov, P Feichtinger, T Ferber, D Ferlewicz, T Fillinger, C Finck, G Finocchiaro, A Fodor, F Forti, A Frey, B G Fulsom, A Gabrielli, E Ganiev, M Garcia-Hernandez, R Garg, A Garmash, G Gaudino, V Gaur, A Gaz, A Gellrich, G Ghevondyan, D Ghosh, H Ghumaryan, G Giakoustidis, R Giordano, A Giri, B Gobbo, R Godang, O Gogota, P Goldenzweig, W Gradl, S Granderath, E Graziani, D Greenwald, Z Gruberová, T Gu, Y Guan, K Gudkova, S Halder, Y Han, T Hara, K Hayasaka, H Hayashii, S Hazra, C Hearty, M T Hedges, A Heidelbach, I Heredia de la Cruz, M Hernández Villanueva, A Hershenhorn, T Higuchi, E C Hill, M Hoek, M Hohmann, P Horak, C-L Hsu, T Iijima, K Inami, G Inguglia, N Ipsita, A Ishikawa, S Ito, R Itoh, M Iwasaki, P Jackson, W W Jacobs, E-J Jang, Q P Ji, S Jia, Y Jin, A Johnson, H Junkerkalefeld, A B Kaliyar, J Kandra, K H Kang, G Karyan, T Kawasaki, F Keil, C Ketter, C Kiesling, C-H Kim, D Y Kim, K-H Kim, Y-K Kim, H Kindo, K Kinoshita, P Kodyš, T Koga, S Kohani, K Kojima, T Konno, A Korobov, S Korpar, E Kovalenko, R Kowalewski, T M G Kraetzschmar, P Križan, P Krokovny, T Kuhr, J Kumar, M Kumar, K Kumara, T Kunigo, A Kuzmin, Y-J Kwon, S Lacaprara, Y-T Lai, T Lam, L Lanceri, J S Lange, M Laurenza, R Leboucher, F R Le Diberder, P Leitl, D Levit, P M Lewis, C Li, L K Li, Y Li, J Libby, Q Y Liu, Z Q Liu, D Liventsev, S Longo, T Lueck, T Luo, C Lyu, Y Ma, M Maggiora, S P Maharana, R Maiti, S Maity, G Mancinelli, R Manfredi, E Manoni, A C Manthei, M Mantovano, D Marcantonio, S Marcello, C Marinas, L Martel, C Martellini, A Martini, T Martinov, L Massaccesi, M Masuda, T Matsuda, D Matvienko, S K Maurya, J A McKenna, R Mehta, F Meier, M Merola, F Metzner, M Milesi, C Miller, M Mirra, K Miyabayashi, G B Mohanty, N Molina-Gonzalez, S Mondal, S Moneta, H-G Moser, M Mrvar, R Mussa, I Nakamura, Y Nakazawa, A Narimani Charan, M Naruki, Z Natkaniec, A Natochii, L Nayak, G Nazaryan, N K Nisar, S Nishida, S Ogawa, H Ono, P Oskin, F Otani, P Pakhlov, G Pakhlova, A Paladino, A Panta, E Paoloni, S Pardi, K Parham, S-H Park, B Paschen, A Passeri, S Patra, S Paul, T K Pedlar, I Peruzzi, R Peschke, R Pestotnik, F Pham, M Piccolo, L E Piilonen, P L M Podesta-Lerma, T Podobnik, S Pokharel, C Praz, S Prell, E Prencipe, M T Prim, H Purwar, N Rad, P Rados, G Raeuber, S Raiz, M Reif, S Reiter, M Remnev, I Ripp-Baudot, G Rizzo, S H Robertson, M Roehrken, J M Roney, A Rostomyan, N Rout, G Russo, D Sahoo, S Sandilya, A Sangal, L Santelj, Y Sato, V Savinov, B Scavino, C Schmitt, M Schnepf, C Schwanda, Y Seino, A Selce, K Senyo, J Serrano, M E Sevior, C Sfienti, W Shan, C Sharma, C P Shen, X D Shi, T Shillington, J-G Shiu, D Shtol, B Shwartz, A Sibidanov, F Simon, J B Singh, J Skorupa, R J Sobie, M Sobotzik, A Soffer, A Sokolov, E Solovieva, S Spataro, B Spruck, M Starič, P Stavroulakis, S Stefkova, Z S Stottler, R Stroili, J Strube, M Sumihama, K Sumisawa, W Sutcliffe, H Svidras, M Takahashi, M Takizawa, U Tamponi, K Tanida, F Tenchini, A Thaller, O Tittel, R Tiwary, D Tonelli, E Torassa, N Toutounji, K Trabelsi, I Tsaklidis, M Uchida, I Ueda, Y Uematsu, T Uglov, K Unger, Y Unno, K Uno, S Uno, P Urquijo, Y Ushiroda, S E Vahsen, R van Tonder, G S Varner, K E Varvell, M Veronesi, V S Vismaya, L Vitale, V Vobbilisetti, R Volpe, B Wach, E Waheed, M Wakai, S Wallner, E Wang, M-Z Wang, Z Wang, A Warburton, M Watanabe, S Watanuki, M Welsch, C Wessel, X P Xu, B D Yabsley, S Yamada, W Yan, S B Yang, J H Yin, K Yoshihara, C Z Yuan, L Zani, Y Zhang, V Zhilich, J S Zhou, Q D Zhou, V I Zhukova, R Žlebčík
We present the first comprehensive tests of the universality of the light leptons in the angular distributions of semileptonic B^{0}-meson decays to charged spin-1 charmed mesons. We measure five angular-asymmetry observables as functions of the decay recoil that are sensitive to lepton-universality-violating contributions. We use events where one neutral B is fully reconstructed in ϒ(4S)→BB[over ¯] decays in data corresponding to 189 fb^{-1} integrated luminosity from electron-positron collisions collected with the Belle II detector...
November 3, 2023: Physical Review Letters
#12
JOURNAL ARTICLE
I Adachi, L Aggarwal, H Aihara, N Akopov, A Aloisio, N Anh Ky, D M Asner, H Atmacan, T Aushev, V Aushev, M Aversano, V Babu, H Bae, S Bahinipati, P Bambade, Sw Banerjee, M Barrett, J Baudot, M Bauer, A Baur, A Beaubien, J Becker, P K Behera, J V Bennett, F U Bernlochner, V Bertacchi, M Bertemes, E Bertholet, M Bessner, S Bettarini, B Bhuyan, F Bianchi, T Bilka, D Biswas, D Bodrov, A Bondar, A Bozek, M Bračko, P Branchini, R A Briere, T E Browder, A Budano, S Bussino, M Campajola, L Cao, G Casarosa, C Cecchi, J Cerasoli, M-C Chang, P Chang, P Cheema, V Chekelian, B G Cheon, K Chilikin, K Chirapatpimol, H-E Cho, K Cho, S-K Choi, S Choudhury, J Cochran, L Corona, S Das, F Dattola, S A De La Motte, G de Marino, G De Nardo, M De Nuccio, G De Pietro, R de Sangro, M Destefanis, S Dey, R Dhamija, A Di Canto, F Di Capua, J Dingfelder, Z Doležal, I Domínguez Jiménez, T V Dong, M Dorigo, K Dort, S Dreyer, S Dubey, G Dujany, P Ecker, D Epifanov, P Feichtinger, D Ferlewicz, C Finck, G Finocchiaro, A Fodor, F Forti, A Frey, B G Fulsom, A Gabrielli, E Ganiev, M Garcia-Hernandez, A Garmash, G Gaudino, V Gaur, A Gaz, A Gellrich, G Ghevondyan, D Ghosh, H Ghumaryan, G Giakoustidis, R Giordano, A Giri, A Glazov, B Gobbo, R Godang, O Gogota, P Goldenzweig, W Gradl, E Graziani, D Greenwald, Z Gruberová, T Gu, Y Guan, K Gudkova, Y Han, K Hayasaka, H Hayashii, S Hazra, C Hearty, I Heredia de la Cruz, A Hershenhorn, T Higuchi, E C Hill, M Hoek, M Hohmann, C-L Hsu, T Humair, T Iijima, K Inami, N Ipsita, A Ishikawa, S Ito, R Itoh, M Iwasaki, P Jackson, W W Jacobs, D E Jaffe, E-J Jang, Q P Ji, S Jia, Y Jin, H Junkerkalefeld, A B Kaliyar, J Kandra, G Karyan, T Kawasaki, F Keil, C Ketter, C Kiesling, C-H Kim, D Y Kim, K-H Kim, Y-K Kim, H Kindo, K Kinoshita, P Kodyš, T Koga, S Kohani, K Kojima, A Korobov, S Korpar, R Kowalewski, T M G Kraetzschmar, P Križan, P Krokovny, T Kuhr, J Kumar, M Kumar, R Kumar, K Kumara, A Kuzmin, Y-J Kwon, S Lacaprara, Y-T Lai, T Lam, J S Lange, M Laurenza, R Leboucher, F R Le Diberder, P Leitl, D Levit, P M Lewis, L K Li, J Libby, Q Y Liu, Z Q Liu, D Liventsev, S Longo, T Lueck, C Lyu, Y Ma, M Maggiora, S P Maharana, R Maiti, S Maity, R Manfredi, E Manoni, M Mantovano, D Marcantonio, S Marcello, C Marinas, C Martellini, A Martini, T Martinov, L Massaccesi, M Masuda, T Matsuda, K Matsuoka, D Matvienko, S K Maurya, J A McKenna, R Mehta, F Meier, M Merola, F Metzner, M Milesi, C Miller, M Mirra, K Miyabayashi, G B Mohanty, N Molina-Gonzalez, S Mondal, S Moneta, H-G Moser, M Mrvar, R Mussa, I Nakamura, Y Nakazawa, A Narimani Charan, M Naruki, Z Natkaniec, A Natochii, L Nayak, G Nazaryan, N K Nisar, S Nishida, H Ono, F Otani, E R Oxford, P Pakhlov, G Pakhlova, A Paladino, A Panta, E Paoloni, S Pardi, A Passeri, S Patra, S Paul, T K Pedlar, I Peruzzi, R Peschke, R Pestotnik, F Pham, M Piccolo, L E Piilonen, T Podobnik, S Pokharel, C Praz, S Prell, E Prencipe, M T Prim, H Purwar, P Rados, G Raeuber, S Raiz, M Reif, S Reiter, M Remnev, I Ripp-Baudot, G Rizzo, J M Roney, A Rostomyan, N Rout, G Russo, S Sandilya, A Sangal, L Santelj, Y Sato, V Savinov, B Scavino, C Schmitt, C Schwanda, A J Schwartz, Y Seino, A Selce, K Senyo, J Serrano, M E Sevior, C Sfienti, W Shan, X D Shi, T Shillington, J-G Shiu, D Shtol, A Sibidanov, F Simon, R J Sobie, M Sobotzik, A Soffer, A Sokolov, E Solovieva, S Spataro, B Spruck, M Starič, P Stavroulakis, Z S Stottler, R Stroili, M Sumihama, H Svidras, M Takahashi, M Takizawa, U Tamponi, K Tanida, F Tenchini, O Tittel, D Tonelli, E Torassa, K Trabelsi, I Tsaklidis, K Unger, Y Unno, K Uno, S Uno, P Urquijo, Y Ushiroda, S E Vahsen, R van Tonder, K E Varvell, M Veronesi, V S Vismaya, L Vitale, R Volpe, B Wach, S Wallner, E Wang, M-Z Wang, X L Wang, Z Wang, A Warburton, M Watanabe, C Wessel, E Won, X P Xu, B D Yabsley, S Yamada, W Yan, S B Yang, K Yoshihara, C Z Yuan, Y Yusa, Y Zhang, V Zhilich, J S Zhou, Q D Zhou, V I Zhukova, R Žlebčík
We measure the lifetime of the D_{s}^{+} meson using a data sample of 207 fb^{-1} collected by the Belle II experiment running at the SuperKEKB asymmetric-energy e^{+}e^{-} collider. The lifetime is determined by fitting the decay-time distribution of a sample of 116×10^{3} D_{s}^{+}→ϕπ^{+} decays. Our result is τ_{D_{s}^{+}}=(499.5±1.7±0.9) fs, where the first uncertainty is statistical and the second is systematic. This result is significantly more precise than previous measurements...
October 27, 2023: Physical Review Letters
#13
JOURNAL ARTICLE
Tania L Maxwell, André S Rovai, Maria Fernanda Adame, Janine B Adams, José Álvarez-Rogel, William E N Austin, Kim Beasy, Francesco Boscutti, Michael E Böttcher, Tjeerd J Bouma, Richard H Bulmer, Annette Burden, Shannon A Burke, Saritta Camacho, Doongar R Chaudhary, Gail L Chmura, Margareth Copertino, Grace M Cott, Christopher Craft, John Day, Carmen B de Los Santos, Lionel Denis, Weixin Ding, Joanna C Ellison, Carolyn J Ewers Lewis, Luise Giani, Maria Gispert, Swanne Gontharet, José A González-Pérez, M Nazaret González-Alcaraz, Connor Gorham, Anna Elizabeth L Graversen, Anthony Grey, Roberta Guerra, Qiang He, James R Holmquist, Alice R Jones, José A Juanes, Brian P Kelleher, Karen E Kohfeld, Dorte Krause-Jensen, Anna Lafratta, Paul S Lavery, Edward A Laws, Carmen Leiva-Dueñas, Pei Sun Loh, Catherine E Lovelock, Carolyn J Lundquist, Peter I Macreadie, Inés Mazarrasa, J Patrick Megonigal, Joao M Neto, Juliana Nogueira, Michael J Osland, Jordi F Pagès, Nipuni Perera, Eva-Maria Pfeiffer, Thomas Pollmann, Jacqueline L Raw, María Recio, Ana Carolina Ruiz-Fernández, Sophie K Russell, John M Rybczyk, Marek Sammul, Christian Sanders, Rui Santos, Oscar Serrano, Matthias Siewert, Craig Smeaton, Zhaoliang Song, Carmen Trasar-Cepeda, Robert R Twilley, Marijn Van de Broek, Stefano Vitti, Livia Vittori Antisari, Baptiste Voltz, Christy N Wails, Raymond D Ward, Melissa Ward, Jaxine Wolfe, Renmin Yang, Sebastian Zubrzycki, Emily Landis, Lindsey Smart, Mark Spalding, Thomas A Worthington
Tidal marshes store large amounts of organic carbon in their soils. Field data quantifying soil organic carbon (SOC) stocks provide an important resource for researchers, natural resource managers, and policy-makers working towards the protection, restoration, and valuation of these ecosystems. We collated a global dataset of tidal marsh soil organic carbon (MarSOC) from 99 studies that includes location, soil depth, site name, dry bulk density, SOC, and/or soil organic matter (SOM). The MarSOC dataset includes 17,454 data points from 2,329 unique locations, and 29 countries...
November 11, 2023: Scientific Data
#14
JOURNAL ARTICLE
Kien Vu Trung, Christian Heise, Einas Abou-Ali, Francesco Auriemma, Elias Karam, Sophia E van der Wiel, Marco J Bruno, Fabrice Caillol, Marc Giovannini, Viliam Masaryk, Uwe Will, Andrea Anderloni, Enrique Pérez-Cuadrado-Robles, Ana Dugic, Benjamin Meier, Woo H Paik, Maria C Petrone, Dörte Wichmann, Mario Dinis-Ribeiro, Tiago C Gonçalves, Edris Wedi, Arthur Schmidt, Aiste Gulla, Albrecht Hoffmeister, Jonas Rosendahl, Jean Philippe Ratone, Rita Saadeh, Alessandro Repici, Pierre Deprez, Alain Sauvanet, Francois R Souche, Jean M Fabre, Steffen Muehldorfer, Karel Caca, Matthias Löhr, Patrick Michl, Sebastian Krug, Sara Regner, Sebastien Gaujoux, Marcus Hollenbach
BACKGROUND AND AIMS: Ampullary lesions (AL) of the minor duodenal papilla are extremely rare. Endoscopic papillectomy (EP) is a routinely used treatment for AL of the major duodenal papilla but the role of EP for minor AL has not been accurately studied. METHODS: We identified 20 patients with AL of minor duodenal papilla out of the multicentric database from the ESAP study that included 1422 EPs. We used the propensity score matching (nearest-neighbor method), to match these cases with ampullary lesions of the major duodenal papilla based on age, gender, histologic subtype and size of the lesion in a 1:2-ratio...
November 9, 2023: Gastrointestinal Endoscopy
#15
JOURNAL ARTICLE
Bob P Hermans, Wilson W L Li, Edwin A Roozen, Daniël I M van Dort, Shoko Vos, Stefan M van der Heide, Erik H F M van der Heijden, Richard P G Ten Broek, Harry van Goor, Ad F T M Verhagen
BACKGROUND: No validated and standardized animal models of pulmonary air leakage (PAL) exist for testing aerostatic efficacy of lung sealants. Lack of negative control groups in published studies and intrinsic sealing mechanisms of healthy animal lungs might contribute to a translational gap, leading to poor clinical results. This study aims to address the impact of intrinsic sealing mechanisms on the validity of PAL models, and investigate the conditions required for an ovine model of PAL for lung sealant testing...
September 28, 2023: Journal of Thoracic Disease
#16
JOURNAL ARTICLE
Shalaila S Haas, Ruiyang Ge, Ingrid Agartz, G Paul Amminger, Ole A Andreassen, Peter Bachman, Inmaculada Baeza, Sunah Choi, Tiziano Colibazzi, Vanessa L Cropley, Camilo de la Fuente-Sandoval, Bjørn H Ebdrup, Adriana Fortea, Paolo Fusar-Poli, Birte Yding Glenthøj, Louise Birkedal Glenthøj, Kristen M Haut, Rebecca A Hayes, Karsten Heekeren, Christine I Hooker, Wu Jeong Hwang, Neda Jahanshad, Michael Kaess, Kiyoto Kasai, Naoyuki Katagiri, Minah Kim, Jochen Kindler, Shinsuke Koike, Tina D Kristensen, Jun Soo Kwon, Stephen M Lawrie, Irina Lebedeva, Jimmy Lee, Imke L J Lemmers-Jansen, Ashleigh Lin, Xiaoqian Ma, Daniel H Mathalon, Philip McGuire, Chantal Michel, Romina Mizrahi, Masafumi Mizuno, Paul Møller, Ricardo Mora-Durán, Barnaby Nelson, Takahiro Nemoto, Merete Nordentoft, Dorte Nordholm, Maria A Omelchenko, Christos Pantelis, Jose C Pariente, Jayachandra M Raghava, Francisco Reyes-Madrigal, Jan I Røssberg, Wulf Rössler, Dean F Salisbury, Daiki Sasabayashi, Ulrich Schall, Lukasz Smigielski, Gisela Sugranyes, Michio Suzuki, Tsutomu Takahashi, Christian K Tamnes, Anastasia Theodoridou, Sophia I Thomopoulos, Paul M Thompson, Alexander S Tomyshev, Peter J Uhlhaas, Tor G Værnes, Therese A M J van Amelsvoort, Theo G M van Erp, James A Waltz, Christina Wenneberg, Lars T Westlye, Stephen J Wood, Juan H Zhou, Dennis Hernaus, Maria Jalbrzikowski, René S Kahn, Cheryl M Corcoran, Sophia Frangou
IMPORTANCE: The lack of robust neuroanatomical markers of psychosis risk has been traditionally attributed to heterogeneity. A complementary hypothesis is that variation in neuroanatomical measures in individuals at psychosis risk may be nested within the range observed in healthy individuals. OBJECTIVE: To quantify deviations from the normative range of neuroanatomical variation in individuals at clinical high risk for psychosis (CHR-P) and evaluate their overlap with healthy variation and their association with positive symptoms, cognition, and conversion to a psychotic disorder...
October 11, 2023: JAMA Psychiatry
#17
JOURNAL ARTICLE
Jonathan Walgraeve, Borja Ferrero-Bordera, Sandra Maaß, Dörte Becher, Ruth Schwerdtfeger, Jan Maarten van Dijl, Michael Seefried
The bacterium Bacillus subtilis is of high importance both as a model organism for Gram-positive bacteria and as an industrial workhorse in the production of biomolecules. In recent years, advancements have been made to engineer the bacterium even further toward industrial applications. In this study, we present a novel screening method for mutant libraries using diamide, an oxidizing agent that binds free thiols and creates disulfide bonds between them, thereby causing a so-called "disulfide stress" in bacteria...
October 11, 2023: Microbiology Spectrum
#18
JOURNAL ARTICLE
Ayşegül Öktem, David Núñez-Nepomuceno, Borja Ferrero-Bordera, Jonathan Walgraeve, Michael Seefried, Manuela Gesell Salazar, Leif Steil, Stephan Michalik, Sandra Maaß, Dörte Becher, Ulrike Mäder, Uwe Völker, Jan Maarten van Dijl
Bacillus subtilis is a Gram-positive bacterium that is well-known for its high secretory capacity. Although secretion of homologous proteins is extremely efficient, secretion of heterologous proteins imposes what is known as "secretion stress" on the cells. This is not desirable in an industrial setting, because the bacterial secretion stress responses can adversely affect product yields. So far, the main approach to reduce such counterproductive secretion stress responses has been to remove components of the CssR-CssS two-component regulatory system, including the CssR-CssS-regulated quality control proteases HtrA and/or HtrB...
October 11, 2023: Microbiology Spectrum
#19
JOURNAL ARTICLE
I Adachi, K Adamczyk, L Aggarwal, H Ahmed, H Aihara, N Akopov, A Aloisio, N Anh Ky, D M Asner, H Atmacan, T Aushev, V Aushev, M Aversano, V Babu, H Bae, S Bahinipati, P Bambade, Sw Banerjee, S Bansal, M Barrett, J Baudot, M Bauer, A Baur, A Beaubien, J Becker, P K Behera, J V Bennett, E Bernieri, F U Bernlochner, V Bertacchi, M Bertemes, E Bertholet, M Bessner, S Bettarini, V Bhardwaj, B Bhuyan, F Bianchi, T Bilka, S Bilokin, D Biswas, A Bobrov, D Bodrov, A Bolz, J Borah, A Bozek, M Bračko, P Branchini, T E Browder, A Budano, S Bussino, M Campajola, L Cao, G Casarosa, C Cecchi, J Cerasoli, M-C Chang, P Chang, R Cheaib, P Cheema, V Chekelian, Y Q Chen, B G Cheon, K Chilikin, K Chirapatpimol, H-E Cho, K Cho, S-J Cho, S-K Choi, S Choudhury, D Cinabro, J Cochran, L Corona, L M Cremaldi, S Cunliffe, T Czank, S Das, F Dattola, E De La Cruz-Burelo, S A De La Motte, G de Marino, G De Nardo, M De Nuccio, G De Pietro, R de Sangro, M Destefanis, S Dey, A De Yta-Hernandez, R Dhamija, A Di Canto, F Di Capua, J Dingfelder, Z Doležal, I Domínguez Jiménez, T V Dong, M Dorigo, K Dort, D Dossett, S Dreyer, S Dubey, G Dujany, P Ecker, M Eliachevitch, D Epifanov, P Feichtinger, T Ferber, D Ferlewicz, T Fillinger, C Finck, G Finocchiaro, A Fodor, F Forti, A Frey, B G Fulsom, A Gabrielli, E Ganiev, M Garcia-Hernandez, A Garmash, G Gaudino, V Gaur, A Gaz, A Gellrich, G Ghevondyan, D Ghosh, H Ghumaryan, G Giakoustidis, R Giordano, A Giri, A Glazov, B Gobbo, R Godang, O Gogota, P Goldenzweig, W Gradl, T Grammatico, S Granderath, E Graziani, D Greenwald, Z Gruberová, T Gu, Y Guan, K Gudkova, J Guilliams, S Halder, Y Han, T Hara, K Hayasaka, H Hayashii, S Hazra, C Hearty, M T Hedges, I Heredia de la Cruz, M Hernández Villanueva, A Hershenhorn, T Higuchi, E C Hill, H Hirata, M Hoek, M Hohmann, C-L Hsu, T Humair, T Iijima, K Inami, G Inguglia, N Ipsita, A Ishikawa, S Ito, R Itoh, M Iwasaki, P Jackson, W W Jacobs, D E Jaffe, E-J Jang, Q P Ji, S Jia, Y Jin, A Johnson, K K Joo, H Junkerkalefeld, H Kakuno, M Kaleta, D Kalita, A B Kaliyar, J Kandra, K H Kang, S Kang, R Karl, G Karyan, T Kawasaki, F Keil, C Ketter, C Kiesling, C-H Kim, D Y Kim, K-H Kim, Y-K Kim, H Kindo, P Kodyš, T Koga, S Kohani, K Kojima, T Konno, A Korobov, S Korpar, E Kovalenko, R Kowalewski, T M G Kraetzschmar, P Križan, P Krokovny, T Kuhr, J Kumar, M Kumar, R Kumar, K Kumara, T Kunigo, A Kuzmin, Y-J Kwon, S Lacaprara, Y-T Lai, T Lam, L Lanceri, J S Lange, M Laurenza, K Lautenbach, R Leboucher, F R Le Diberder, P Leitl, D Levit, P M Lewis, C Li, L K Li, Y B Li, J Libby, K Lieret, Q Y Liu, Z Q Liu, D Liventsev, S Longo, A Lozar, T Lueck, C Lyu, Y Ma, M Maggiora, S P Maharana, R Maiti, S Maity, R Manfredi, E Manoni, A C Manthei, M Mantovano, D Marcantonio, S Marcello, C Marinas, L Martel, C Martellini, A Martini, T Martinov, L Massaccesi, M Masuda, T Matsuda, K Matsuoka, D Matvienko, S K Maurya, J A McKenna, R Mehta, M Merola, F Metzner, M Milesi, C Miller, M Mirra, K Miyabayashi, H Miyake, R Mizuk, G B Mohanty, N Molina-Gonzalez, S Mondal, S Moneta, H-G Moser, M Mrvar, R Mussa, I Nakamura, K R Nakamura, M Nakao, H Nakayama, H Nakazawa, Y Nakazawa, A Narimani Charan, M Naruki, D Narwal, Z Natkaniec, A Natochii, L Nayak, M Nayak, G Nazaryan, C Niebuhr, N K Nisar, S Nishida, S Ogawa, H Ono, Y Onuki, P Oskin, F Otani, P Pakhlov, G Pakhlova, A Paladino, A Panta, E Paoloni, S Pardi, K Parham, J Park, S-H Park, B Paschen, A Passeri, S Patra, S Paul, T K Pedlar, I Peruzzi, R Peschke, R Pestotnik, F Pham, M Piccolo, L E Piilonen, G Pinna Angioni, P L M Podesta-Lerma, T Podobnik, S Pokharel, L Polat, C Praz, S Prell, E Prencipe, M T Prim, H Purwar, N Rad, P Rados, G Raeuber, S Raiz, A Ramirez Morales, M Reif, S Reiter, M Remnev, I Ripp-Baudot, G Rizzo, L B Rizzuto, S H Robertson, D Rodríguez Pérez, M Roehrken, J M Roney, A Rostomyan, N Rout, G Russo, D Sahoo, D A Sanders, S Sandilya, A Sangal, L Santelj, Y Sato, V Savinov, B Scavino, M Schnepf, J Schueler, C Schwanda, Y Seino, A Selce, K Senyo, J Serrano, M E Sevior, C Sfienti, W Shan, C Sharma, C P Shen, X D Shi, T Shillington, J-G Shiu, D Shtol, B Shwartz, A Sibidanov, F Simon, J B Singh, J Skorupa, R J Sobie, M Sobotzik, A Soffer, A Sokolov, E Solovieva, S Spataro, B Spruck, M Starič, P Stavroulakis, S Stefkova, Z S Stottler, R Stroili, J Strube, Y Sue, M Sumihama, K Sumisawa, W Sutcliffe, S Y Suzuki, H Svidras, M Takahashi, M Takizawa, U Tamponi, S Tanaka, K Tanida, H Tanigawa, F Tenchini, A Thaller, R Tiwary, D Tonelli, E Torassa, N Toutounji, K Trabelsi, I Tsaklidis, M Uchida, I Ueda, Y Uematsu, T Uglov, K Unger, Y Unno, K Uno, S Uno, P Urquijo, Y Ushiroda, S E Vahsen, R van Tonder, G S Varner, K E Varvell, A Vinokurova, V S Vismaya, L Vitale, V Vobbilisetti, R Volpe, A Vossen, B Wach, M Wakai, H M Wakeling, S Wallner, E Wang, M-Z Wang, X L Wang, Z Wang, A Warburton, M Watanabe, S Watanuki, M Welsch, C Wessel, E Won, X P Xu, B D Yabsley, S Yamada, W Yan, S B Yang, H Ye, J Yelton, J H Yin, Y M Yook, K Yoshihara, C Z Yuan, Y Yusa, L Zani, Y Zhai, Y Zhang, V Zhilich, J S Zhou, Q D Zhou, X Y Zhou, V I Zhukova, R Žlebčík
We report the first search for a nonstandard-model resonance decaying into τ pairs in e^{+}e^{-}→μ^{+}μ^{-}τ^{+}τ^{-} events in the 3.6-10 GeV/c^{2} mass range. We use a 62.8 fb^{-1} sample of e^{+}e^{-} collisions collected at a center-of-mass energy of 10.58 GeV by the Belle II experiment at the SuperKEKB collider. The analysis probes three different models predicting a spin-1 particle coupling only to the heavier lepton families, a Higgs-like spin-0 particle that couples preferentially to charged leptons (leptophilic scalar), and an axionlike particle, respectively...
September 22, 2023: Physical Review Letters
#20
JOURNAL ARTICLE
A H A Lavell, A E Schramade, J J Sikkens, K van der Straten, K A van Dort, M A Slim, B Appelman, L A van Vught, A P J Vlaar, N A Kootstra, M J van Gils, Y M Smulders, R T de Jongh, M K Bomers
BACKGROUND: To improve effectiveness of vaccination against SARS-CoV-2, it is important to identify factors that influence the immune response induced by vaccination. Evidence for the role of vitamin D in immune response against SARS-CoV-2 is contradictory. It is therefore of interest whether 25-hydroxyvitamin D (25[OH]D) concentrations affect the humoral and/or cellular response following SARS-CoV-2 vaccination. METHODS: In this prospective cohort study, blood samples were collected from 98 SARS-CoV-2 naive health care workers (HCW) receiving the first two doses of either BNT162b2 or mRNA-1273 in 2021...
September 27, 2023: Vaccine
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