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Physical activity and stress

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https://www.readbyqxmd.com/read/28918244/determinants-and-regulation-of-protein-turnover-in-yeast
#1
Miguel Martin-Perez, Judit Villén
Protein turnover maintains the recycling needs of the proteome, and its malfunction has been linked to aging and age-related diseases. However, not all proteins turnover equally, and the factors that contribute to accelerate or slow down turnover are mostly unknown. We measured turnover rates for 3,160 proteins in exponentially growing yeast and analyzed their dependence on physical, functional, and genetic properties. We found that functional characteristics, including protein localization, complex membership, and connectivity, have greater effect on turnover than sequence elements...
September 13, 2017: Cell Systems
https://www.readbyqxmd.com/read/28915274/prevalence-of-mind-and-body-exercises-mbe-in-relation-to-demographics-self-rated-health-and-purchases-of-prescribed-psychotropic-drugs-and-analgesics
#2
Lina Rådmark, Linda L Magnusson Hanson, Eva Bojner Horwitz, Walter Osika
This study aims to identify any differences regarding gender, age, socioeconomic status (SES), self-rated health, perceived stress and the purchase of prescribed drugs among people who practice mind and body exercises (MBE) extensively compared to people who do not. METHODS: The study includes 3,913 men and 4,803 women aged 20-72 who participated in the Swedish Longitudinal Occupational Survey of Health (SLOSH). The respondents were divided into three groups depending on frequency of MBE practice (never/seldom/often)...
2017: PloS One
https://www.readbyqxmd.com/read/28913421/curvature-and-rho-activation-differentially-control-the-alignment-of-cells-and-stress-fibers
#3
Nathan D Bade, Randall D Kamien, Richard K Assoian, Kathleen J Stebe
In vivo, cells respond to a host of physical cues ranging from substrate stiffness to the organization of micro- and nanoscale fibrous networks. We show that macroscale substrates with radii of curvature from tens to hundreds of micrometers influence cell alignment. In a model system of fibroblasts, isolated cells aligned strongly in the axial direction on cylinders with radii similar to the cell length and more weakly on cylinders of much larger radius. Isolated vascular smooth muscle cells did not align as effectively as fibroblasts...
September 2017: Science Advances
https://www.readbyqxmd.com/read/28912742/perception-action-and-cognition-of-football-referees-in-extreme-temperatures-impact-on-decision-performance
#4
Nadia Gaoua, Rita F de Oliveira, Steve Hunter
Different professional domains require high levels of physical performance alongside fast and accurate decision-making. Construction workers, police officers, firefighters, elite sports men and women, the military and emergency medical professionals are often exposed to hostile environments with limited options for behavioral coping strategies. In this (mini) review we use football refereeing as an example to discuss the combined effect of intense physical activity and extreme temperatures on decision-making and suggest an explicative model...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28911936/exercise-training-in-patients-with-pulmonary-and-systemic-hypertension-a-unique-therapy-for-two-different-diseases
#5
REVIEW
Massimo Leggio, Augusto Fusco, Giorgio Limongelli, Luca Sgorbini
Pulmonary hypertension is a potentially life-threatening condition. Given its evolving definition, the incidence and prevalence of the disease is difficult to define, but registries suggest an increased global awareness. The management of patients with pulmonary arterial hypertension is highly specialised and requires multi-disciplinary input from a range of healthcare professionals, including cardiologists, respiratory physicians, rheumatologists, rehabilitation physicians and cardio-pulmonary physiotherapists...
September 11, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28911309/formulation-quality-control-and-safety-issues-of-nanocarriers-used-for-cancer-treatment
#6
Ismael D Bianco, Marcelo R Ceballos, Cristian Casado, Viviana G Dabbene, Carolina Rizzi, R Kiyomi Mizutamari
Cancer is becoming a leading cause of death in the last years. Although we have seen great advances, most human cancers remain incurable because many patients either do not respond or relapse to treatment. Several lines of research are disclosing new therapeutic targets which lead to new active drugs. However, there are still unsolved problems related to stabilization of the pharmaceutical ingredient in aqueous and biological media, pharmacokinetic and pharmacodynamic profiles and cellular uptake to name just a few...
June 7, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28905076/-life-after-ards
#7
REVIEW
B Sensen, S Braune, G de Heer, T Bein, S Kluge
Patients who survive acute respiratory distress syndrome (ARDS) often suffer from long-term physical and psychological sequelae. Lung function is commonly only mildly reduced, whereas general physical activity and walking distance are often compromised. Most markedly, these patients have a high incidence of depression, anxiety, and posttraumatic stress disorder. The rate of cognitive dysfunction is as high as 70-100% at the time of hospital discharge, and remains 46-80% and 20% one year and five years post discharge, respectively...
September 13, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/28902900/possible-clinical-effects-of-molecular-hydrogen-h2-delivery-during-hemodialysis-in-chronic-dialysis-patients-interim-analysis-in-a-12-month-observation
#8
Masaaki Nakayama, Noritomo Itami, Hodaka Suzuki, Hiromi Hamada, Naoyuki Osaka, Ryo Yamamoto, Kazumasa Tsunoda, Hirofumi Nakano, Kimio Watanabe, Wan-Jun Zhu, Yukio Maruyama, Hiroyuki Terawaki, Shigeru Kabayama, Ryoichi Nakazawa, Mariko Miyazaki, Sadayoshi Ito
BACKGROUND AND AIM: It is supposed that enhanced oxidative stress and inflammation are involved with the poor clinical outcomes in patients on chronic dialysis treatment. Recent studies have shown that molecular hydrogen (H2) is biologically active as an anti-inflammatory agent. Thus, we developed a novel hemodialysis (E-HD) system which delivers H2 (30 to 80 ppb)-enriched dialysis solution, to conduct a prospective observational study (UMIN000004857) in order to compare the long-term outcomes between E-HD and conventional-HD (C-HD) in Japan...
2017: PloS One
https://www.readbyqxmd.com/read/28900256/genomic-and-transcriptomic-analysis-of-the-toluene-degrading-black-yeast-cladophialophora-immunda
#9
Barbara Blasi, Hakim Tafer, Christina Kustor, Caroline Poyntner, Ksenija Lopandic, Katja Sterflinger
Cladophialophora immunda is an ascomycotal species belonging to the group of the black yeasts. These fungi have a thick and melanized cell wall and other physiological adaptations that allows them to cope with several extreme physical and chemical conditions. Member of the group can colonize some of the most extremophilic environments on Earth. Cladophialophora immunda together with a few other species of the order Chaetothyriales show a special association with hydrocarbon polluted environments. The finding that the fungus is able to completely mineralize toluene makes it an interesting candidate for bioremediation purposes...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28898827/purification-and-antioxidant-activity-of-phycocyanin-from-synechococcus-sp-r42dm-isolated-from-industrially-polluted-site
#10
Ravi R Sonani, Stuti Patel, Bela Bhastana, Kinnari Jakharia, Mukesh G Chaubey, Niraj K Singh, Datta Madamwar
The cyanobacterium Synechococcus sp. R42DM, isolated from an industrially polluted site Vatva, Gujarat, India was recognized to produce phycocyanin (PC) as major phycobiliprotein. In present study, the combinatorial approach of chemical and physical methods i.e. Triton-X 100 treatment and ultra-sonication was designed for extraction of PC. From cell extract, the intact and functional-PC was purified up to purity 4.03 by ammonium sulphate fractionation and ion-exchange chromatography. The PC displayed considerable in vitro antioxidant and radical-scavenging activity...
August 31, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28898135/understanding-adolescent-low-back-pain-from-a-multidimensional-perspective-implications-for-management
#11
Peter O'Sullivan, Anne Smith, Darren Beales, Leon Straker
Synopsis Low back pain (LBP) is the leading cause of disability worldwide. It often begins in adolescence, setting a course for later life. We have tracked the time course of LBP in the Raine Study cohort from the age of 14 years into early adulthood. Our work highlights that LBP is already prevalent at 14 years increasing across adolescence and into early adulthood. It is often co-morbid with other musculoskeletal pain. For some adolescents LBP has little impact - while for others its impact includes care seeking, taking medication, taking time off school and work, as well as modifying physical and functional activity...
September 12, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28894916/structural-and-functional-diversity-of-collectins-and-ficolins-and-their-relationship-to-disease
#12
REVIEW
Mark Howard, Conrad A Farrar, Steven H Sacks
Pattern recognition molecules are sensors for the innate immune system and trigger a number of pathophysiological functions after interaction with the corresponding ligands on microorganisms or altered mammalian cells. Of those pattern recognition molecules used by the complement system, collagen-like lectins (collectins) are an important subcomponent. Whereas the best known of these collectins, mannose-binding lectin, largely occurs as a circulating protein following production by hepatocytes, the most recently described collectins exhibit strong local biosynthesis...
September 11, 2017: Seminars in Immunopathology
https://www.readbyqxmd.com/read/28894046/the-role-of-trophic-factors-and-inflammatory-processes-in-physical-activity-induced-neuroprotection-in-parkinson-s-disease
#13
Ewelina Pałasz, Agnieszka Bąk, Anna Gąsiorowska, Grażyna Niewiadomska
Glial cells and neurotrophins play an important role in maintaining homeostasis of the CNS. Disturbances of their function can lead to a number of nervous system diseases, including Parkinson's disease (PD). Current clinical studies provide evidence that moderate physical activity adapted to the health status of PD patients can support pharmacological treatment, slow down the onset of motor impairments, and extend the patients period of independence. Physical activity, by stimulating the production and release of endogenous trophic factors, prevents the neurodegeneration of dopaminergic neurons via inhibition of inflammatory processes and the reduction of oxidative stress...
January 4, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28893726/a-web-based-lifestyle-medicine-curriculum-facilitating-education-about-lifestyle-medicine-behavioral-change-and-health-care-outcomes
#14
Elizabeth Pegg Frates, Ryan C Xiao, Deepa Sannidhi, Yasamina McBride, Tracie McCargo, Theodore A Stern
BACKGROUND: Lifestyle medicine is the science and application of healthy lifestyles as interventions for the prevention and treatment of disease, and has gained significant momentum as a specialty in recent years. College is a critical time for maintenance and acquisition of healthy habits. Longer-term, more intensive web-based and in-person lifestyle medicine interventions can have a positive effect. Students who are exposed to components of lifestyle medicine in their education have improvements in their health behaviors...
September 11, 2017: JMIR Medical Education
https://www.readbyqxmd.com/read/28890898/antifatigue-functions-and-mechanisms-of-edible-and-medicinal-mushrooms
#15
REVIEW
Ping Geng, Ka-Chai Siu, Zhaomei Wang, Jian-Yong Wu
Fatigue is the symptom of tiredness caused by physical and/or psychological stresses. As fatigue is becoming a serious problem in the modern society affecting human health, work efficiency, and quality of life, effective antifatigue remedies other than pharmacological drugs or therapies are highly needed. Mushrooms have been widely used as health foods, because of their various bioactive constituents such as polysaccharides, proteins, vitamins, minerals, and dietary fiber. This paper reviews the major findings from previous studies on the antifatigue effects, the active components of mushrooms, and the possible mechanisms...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28889845/effect-of-electroacupuncture-rehabilitation-in-transverse-myelitis-a-case-report
#16
Sriloy Mohanty, Rabin Lal Shrestha
A 32-year-old male diagnosed with transverse myelitis in 2013 came to our clinic in 2015 with complaints of paraplegia, sensory disturbances, pain, exertional dyspnea, poor quality of sleep, emotional instability, and depression. This was a recurrent attack that had been exacerbated by post-traumatic stress. Owing to pain and functional disabilities, he was struggling to actively participate in the treatment modalities offered at our center. A modified protocol of electroacupuncture was planned for a period of 21 days, every day, with each session lasting for 30 minutes...
August 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28887988/enhanced-bovine-serum-albumin-absorption-on-the-n-hydroxysuccinimide-activated-graphene-oxide-and-its-corresponding-cell-affinity
#17
Kun Xiong, Qingbo Fan, Tingting Wu, Haishan Shi, Lin Chen, Minhao Yan
By successively reacting with N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS), the carboxyl on the graphene oxide (GO) surface was successfully activated into NHS active ester. In this study, bovine serum albumin (BSA) was selected as a model protein, used for studying the protein absorption capacity of the NHS activated GO (GO-EDC-NHS). Approximately 12.75mg of BSA could be covalent bonded onto the GO-EDC-NHS surface (BSA-CB-GO), whereas only 6.83mg of BSA physical absorbed onto the GO surface (BSA-NB-GO)...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28887210/can-half-marathon-affect-overall-health-the-yin-yang-of-sport
#18
Luca Dalle Carbonare, Marcello Manfredi, Giuseppe Caviglia, Eleonora Conte, Elisa Robotti, Emilio Marengo, Samuele Cheri, Francesco Zamboni, Daniele Gabbiani, Michela Deiana, Daniela Cecconi, Federico Schena, Monica Mottes, Maria Teresa Valenti
Physical activity improves overall health and counteracts metabolic pathologies. Adipose tissue and bone are important key targets of exercise; the prevalence of diseases associated with suboptimal physical activity levels has increased in recent times as a result of lifestyle changes. Mesenchymal stem cells (MSCs) differentiation in either osteogenic or adipogenic lineage is regulated by many factors. Particularly, the expression of master genes such as RUNX2 and PPARγ2 is essential for MSC commitment to osteogenic or adipogenic differentiation, respectively...
September 5, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28886852/prevalence-of-hypertension-in-professional-drivers-from-the-racer-abpm-study
#19
Anna E Platek, Filip M Szymanski, Krzysztof J Filipiak, Marcin Kotkowski, Anna Rys, Karolina Semczuk-Kaczmarek, Karolina Adamkiewicz
Professional drivers are a group exposed to many cardiovascular risk factors. Nonsystematic working hours, stress, low physical activity, and unhealthy dietary habits are common among professional drivers. These translate into high risk of cardiovascular disease. The aim of the current analysis was to establish the prevalence of arterial hypertension in a group of continuous professional drivers. The RACER (Risk of Adverse Cardiovascular Events among professional dRivers in Poland) study is a prospective study focused on assessing cardiovascular risk factors in professional drivers...
August 8, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28886697/correlates-of-alcohol-consumption-among-germans-in-the-second-half-of-life-results-of-a-population-based-observational-study
#20
André Hajek, Jens-Oliver Bock, Siegfried Weyerer, Hans-Helmut König
BACKGROUND: Several studies have investigated the predictors of alcohol consumption behavior among adolescents and young adults. However, the body of evidence about the relationship between in particular psychological factors and alcohol consumption among individuals in the second half of life is still limited. Hence, we aimed at identifying factors associated with alcohol consumption among individuals aged 40 and above, especially focusing on psychological correlates. METHODS: Data were derived from a population-based sample of community-dwelling individuals aged 40 to 95 years (n = 7820) in Germany...
September 8, 2017: BMC Geriatrics
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