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Physical activity and stress

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https://www.readbyqxmd.com/read/28097269/recurrence-rate-of-stress-urinary-incontinence-in-females-with-initial-cure-after-transobturator-tape-procedure-at-3-year-follow-up
#1
Taeyong Jun, Hyun Sik Yoon, Hyung Suk Kim, Jeong Woo Lee, Jungbum Bae, Hae Won Lee
PURPOSE: To assess recurrence rates of urinary incontinence in women with initial cure after transobturator tape (TOT) procedure at 3-year follow-up. MATERIALS AND METHODS: Between June 2006 and May 2013, a total of 402 consecutive patients underwent the TOT procedure for female stress urinary incontinence (SUI) at Dongguk University Ilsan Hospital. Of the 402 patients, 223 had sufficient medical records for analysis. Therefore, they were followed-up for 3 years postoperatively...
January 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28097073/handling-stress-may-confound-murine-gut-microbiota-studies
#2
Cary R Allen-Blevins, Xiaomeng You, Katie Hinde, David A Sela
BACKGROUND: Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO), the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously digested by the human infant but are able to be metabolized by certain species of gut microbiota, including Bifidobacterium longum subsp. infantis (B. infantis), a species sensitive to host stress (Bailey & Coe, 2004). Exposure to gut bacteria like B...
2017: PeerJ
https://www.readbyqxmd.com/read/28096637/prevalence-of-female-sexual-dysfunction-among-indian-fertile-females
#3
Vineet V Mishra, Sakshi Nanda, Bhumika Vyas, Rohina Aggarwal, Sumesh Choudhary, Suwa Ram Saini
BACKGROUND: Female sexual dysfunction (FSD) is described as difficulty experienced by a female during any stage of a normal sexual activity including physical pleasure, desire, arousal, or orgasm. There are various factors responsible for FSD including psychological status of a person, gynecological or medical problems, long use of certain drugs, and social beliefs. OBJECTIVES: To study the prevalence and various factors associated with FSD. MATERIALS AND METHODS: Study Design - This study design was a cross-sectional observational study conducted at Tertiary Care Centre, in Ahmedabad from June 2015 to March 2016...
October 2016: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28096522/control-of-food-intake-by-gastrointestinal-peptides-mechanisms-of-action-and-possible-modulation-in-the-treatment-of-obesity
#4
REVIEW
Philip Prinz, Andreas Stengel
This review focuses on the control of appetite by food intake-regulatory peptides secreted from the gastrointestinal tract, namely cholecystokinin, glucagon-like peptide 1, peptide YY, ghrelin, and the recently discovered nesfatin-1 via the gut-brain axis. Additionally, we describe the impact of external factors such as intake of different nutrients or stress on the secretion of gastrointestinal peptides. Finally, we highlight possible conservative-physical activity and pharmacotherapy-treatment strategies for obesity as well as surgical techniques such as deep brain stimulation and bariatric surgery also altering these peptidergic pathways...
January 17, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28095308/lithium-induced-malaise-does-not-interfere-with-adaptation-of-the-hypothalamic-pituitary-adrenal-axis-to-stress
#5
Maria Sanchís-Ollé, Juan Antonio Ortega-Sánchez, Xavier Belda, Humberto Gagliano, Roser Nadal, Antonio Armario
We have recently demonstrated that adaptation of the hypothalamic-pituitary-adrenal (HPA) axis to repeated exposure to a stressor does not follow the rules of habituation and can be fully expressed after a single experience with severe stressors. In the present work we tested the hypothesis that adaptation could be impaired if animals experience malaise during initial exposure to the stressor. To this end, animals were allowed to drink saccharin for 30min before being exposed for 3h to immobilization on boards (IMO), a severe stressor; then they were given either saline or lithium ip after the first hour of IMO...
January 14, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28092244/-depression-and-burden-on-primary-caregivers-of-elderly-persons-with-physical-dependence-of-the-umf-171
#6
Cristina Navarro-Sandoval, Lizbeth Carlota Uriostegui-Espíritu, Edna Gabriela Delgado-Quiñones, Minerva Natalia Sahagún-Cuevas
BACKGROUND: According to the National Health and Nutrition Survey of 2012, more than a quarter of older adults (26.9%) have some degree of disability, requiring a primary caregiver to perform basic activities of daily living. The aim is to determine the prevalence of depression and burden on primary caregivers of elderly persons with physical dependence. METHODS: A descriptive cross-sectional study with non-probability sampling that included the primary caregivers of elderly patients with physical dependence...
January 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28089410/microparticle-detection-to-guide-platelet-management-for-the-reduction-of-platelet-refractoriness-in-children-a-study-proposal
#7
REVIEW
Peter Kanzler, Andrew Mahoney, Gerda Leitner, Volker Witt, Elisabeth Maurer-Spurej
Microparticles have been shown to shed from a variety of viable cells as a consequence of inflammatory processes, activation or physical stress. Seventy to 90% of circulating microparticles are thought to be platelet-derived. The content of microparticles in blood collected from normal blood donors is highly variable and transfers into the final blood component. Elevated microparticle content (MPC) in donor blood might indicate an asymptomatic clinical condition of the donor which might affect the transfusion recipient, particularly pediatric patients...
December 29, 2016: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28087957/cardiovascular-risk-assessment-between-urban-and-rural-population-in-malaysia
#8
I Noor Hassim, M R Norazman, M Diana, Y Khairul Hazdi, I Rosnah
INTRODUCTION: Cardiovascular disease (CVD) caused significant burden to Malaysia as it accounted for 36% of total deaths. This study aims to evaluate the burden of cardiovascular risk factors among Malaysian adult and assess the difference between urban and rural population in the selected communities. METHODS: This study is part of the ongoing Prospective Urban Rural Epidemiology (PURE) database, whereby the baseline data were collected since June 2008. CVD risk was measured using INTERHEART risk score which comprised of eleven risk factors i...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28087932/the-complexity-of-fungal-vision
#9
Reinhard Fischer, Jesus Aguirre, Alfredo Herrera-Estrella, Luis M Corrochano
Life, as we know it, would not be possible without light. Light is not only a primary source of energy, but also an important source of information for many organisms. To sense light, only a few photoreceptor systems have developed during evolution. They are all based on an organic molecule with conjugated double bonds that allows energy transfer from visible (or UV) light to its cognate protein to translate the primary physical photoresponse to cell-biological actions. The three main classes of receptors are flavin-based blue-light, retinal-based green-light (such as rhodopsin), and linear tetrapyrrole-based red-light sensors...
December 2016: Microbiology Spectrum
https://www.readbyqxmd.com/read/28087154/evaluation-of-serial-high-sensitivity-troponin-t-levels-in-individuals-without-overt-coronary-heart-disease-following-exercise-stress-testing
#10
Yousef M E Saad, Hanan Idris, Ibrahim M Shugman, Krishna K Kadappu, Rohan Rajaratnam, Liza Thomas, Christian Mussap, Dominic Y C Leung, Craig P Juergens, John K French
BACKGROUND: Detectable levels of high sensitivity (cardiac) troponin T (HsTnT), occur in the majority of patients with stable coronary heart disease (CHD), and often in 'healthy' individuals. Extreme physical activity may lead to marked elevations in creatine kinase MB and TnT levels. However, whether HsTnT elevations occur commonly after exercise stress testing (EST), and if so, whether this has clinical significance, needs clarification. METHODS: To determine whether HsTnT levels become elevated after EST (Bruce protocol) to ≥95% of predicted maximum heart rate in presumed healthy subjects without overt CHD, we assayed HsTnT levels for ∼5h post-EST in 105 subjects (median age 37 years)...
December 9, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28086991/does-waterfall-aerosol-influence-mucosal-immunity-and-chronic-stress-a-randomized-controlled-clinical-trial
#11
Carina Grafetstätter, Martin Gaisberger, Johanna Prossegger, Markus Ritter, Predrag Kolarž, Christina Pichler, Josef Thalhamer, Arnulf Hartl
BACKGROUND: The specific microclimate of alpine waterfalls with high levels of ionized water aerosols has been suggested to trigger beneficial immunological and psychological effects. In the present three-armed randomized controlled clinical study, we focused on effects on (i) immunological reagibility, on (ii) physiological stress responses, and on (iii) stress-related psychological parameters. METHODS: People with moderate to high stress levels (n = 65) spent an active sojourn with daily hiking tours in the National Park Hohe Tauern (Großkirchheim, Austria)...
January 13, 2017: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/28081231/physical-activity-energy-expenditure-nutritional-habits-quality-of-sleep-and-stress-levels-in-shift-working-health-care-personnel
#12
Frederick Charles Roskoden, Janine Krüger, Lena Johanna Vogt, Simone Gärtner, Hans Joachim Hannich, Antje Steveling, Markus M Lerch, Ali A Aghdassi
BACKGROUND: Among health care personnel working regular hours or rotating shifts can affect parameters of general health and nutrition. We have investigated physical activity, sleep quality, metabolic activity and stress levels in health care workers from both groups. METHODS: We prospectively recruited 46 volunteer participants from the workforce of a University Medical Department of which 23 worked in rotating shifts (all nursing) and 21 non-shift regular hours (10 nursing, 13 clerical staff)...
2017: PloS One
https://www.readbyqxmd.com/read/28081177/first-behavioural-characterisation-of-a-knockout-mouse-model-for-the-transforming-growth-factor-tgf-%C3%AE-superfamily-cytokine-mic-1-gdf15
#13
Jac Kee Low, Ananthan Ambikairajah, Kani Shang, David A Brown, Vicky W W Tsai, Samuel N Breit, Tim Karl
Macrophage inhibitory cytokine-1 (MIC-1), also known as growth differentiation factor 15 (GDF15), is a stress response cytokine. MIC-1/GDF15 is secreted into the cerebrospinal fluid and increased levels of MIC-1/GDF15 are associated with a variety of diseases including cognitive decline. Furthermore, Mic-1/Gdf15 knockout mice (Mic-1 KO) weigh more, have increased adiposity, associated with increased spontaneous food intake, and exhibit reduced basal energy expenditure and physical activity. The current study was designed to comprehensively determine the role of MIC-1/GDF15 on behavioural domains of male and female knockout mice including locomotion, exploration, anxiety, cognition, social behaviours, and sensorimotor gating...
2017: PloS One
https://www.readbyqxmd.com/read/28079492/working-with-instruments-ernst-mach-as-material-epistemologist-a-short-introduction
#14
Christoph Hoffmann, Alexandre Métraux
With the death of Ernst Mach on February 19, 1916, one day after his seventy-eighth birthday, a question finally became explicit that had been looming for some time. It was as simple as it was fundamental: who, in the end, was this man, a scientist or a philosopher? The importance of this question for contemporaries can easily be gleaned from the obituaries that appeared in the weeks following Mach's death: one in the Physikalische Zeitschrift, written by Albert Einstein, and another in the Archiv für die Geschichte der Philosophie, written by Mach's former student Heinrich Gomperz...
December 2016: Science in Context
https://www.readbyqxmd.com/read/28077722/higher-heart-rate-variability-is-associated-with-ventromedial-prefrontal-cortex-activity-and-increased-resistance-to-temptation-in-dietary-self-control-challenges
#15
Silvia U Maier, Todd A Hare
: Higher levels of self-control in decision making have been linked to better psychosocial and physical health. A similar link to health outcomes has been reported for heart-rate variability (HRV), a marker of physiological flexibility. Here, we sought to link these two, largely separate, research domains by testing the hypothesis that greater HRV would be associated with better dietary self-control in humans. Specifically, we examined whether total HRV at sedentary rest (measured as the SD of normal-to-normal intervals) can serve as a biomarker for the neurophysiological adaptability that putatively underlies self-controlled behavior...
January 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28073797/physical-and-cultural-determinants-of-postpartum-pelvic-floor-support-and-symptoms-following-vaginal-delivery-a-protocol-for-a-mixed-methods-prospective-cohort-study
#16
Ingrid E Nygaard, Erin Clark, Lauren Clark, Marlene J Egger, Robert Hitchcock, Yvonne Hsu, Peggy Norton, Ana Sanchez-Birkhead, Janet Shaw, Xiaoming Sheng, Michael Varner
INTRODUCTION: Pelvic floor disorders (PFDs), including pelvic organ prolapse (POP), stress and urgency urinary incontinence, and faecal incontinence, are common and arise from loss of pelvic support. Although severe disease often does not occur until women become older, pregnancy and childbirth are major risk factors for PFDs, especially POP. We understand little about modifiable factors that impact pelvic floor function recovery after vaginal birth. This National Institutes of Health (NIH)-funded Program Project, 'Bridging physical and cultural determinants of postpartum pelvic floor support and symptoms following vaginal delivery', uses mixed-methods research to study the influences of intra-abdominal pressure, physical activity, body habitus and muscle fitness on pelvic floor support and symptoms as well as the cultural context in which women experience those changes...
January 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28073493/abiotic-variables-affect-stx-concentration-in-a-meso-oligotrophic-subtropical-coastal-lake-dominated-by-cylindrospermopsis-raciborskii-cyanophyceae
#17
Débora Monteiro Brentano, Eduardo L Hettwer Giehl, Maurício Mello Petrucio
The cyanobacterium Cylindrospermopsis raciborskii is capable of producing toxins including saxitoxin (STX). Few studies have verified the influence of environmental variables on the production of STX and most have only been studied in the laboratory. The goal of this work was to identify the abiotic variables related to STX concentration in situ. The relationship among STX concentration and the physical variables, nutrients and chlorophyll-a (chl-a) concentration was examined in a meso-oligotrophic subtropical coastal lake dominated by C...
June 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073318/effects-of-hydroxyl-functionalized-multiwalled-carbon-nanotubes-on-sperm-health-and-testes-of-wistar-rats
#18
N K Nirmal, K K Awasthi, P J John
Carbon nanotubes (CNTs) are promising candidates for various applications including biomedical purposes. Owing to their remarkable physical, mechanical, electrical and chemical properties, CNTs have become an area of intense research and industrial activity in recent years. Therefore, toxicity and risk assessment studies are becoming increasingly important. The present study was designed to assess the effects of hydroxyl-functionalized multiwalled CNTs (OH-f MWCNTs) on sperm health and testes of adult Wistar rats...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28068485/obesity-in-low-and-middle-income-countries-burden-drivers-and-emerging-challenges
#19
Nicole D Ford, Shivani A Patel, K M Venkat Narayan
We have reviewed the distinctive features of excess weight, its causes, and related prevention and management efforts, as well as data gaps and recommendations for future research in low- and middle-income countries (LMICs). Obesity is rising in every region of the world, and no country has been successful at reversing the epidemic once it has begun. In LMICs, overweight is higher in women compared with men, in urban compared with rural settings, and in older compared with younger individuals; however, the urban-rural overweight differential is shrinking in many countries...
December 23, 2016: Annual Review of Public Health
https://www.readbyqxmd.com/read/28068097/characterization-of-phase-separation-propensity-for-amorphous-spray-dried-dispersions
#20
Daniel McNamara, Shawn Yin, Duohai Pan, George Crull, Peter Timmins, Balvinder Vig
A generalized screening approach, applying isothermal calorimetry at 37°C 100%RH, to formulations of spray dried dispersions (SDDs) for two active pharmaceutical ingredients (APIs) (BMS-903452 and BMS-986034) is demonstrated. APIs 452 and 034, with similar chemotypes, were synthesized and promoted during development for oral dosing. Both APIs were formulated as SDDs for animal exposure studies using the polymer hydroxypropylmethlycellulose acetyl succinate M grade (HPMCAS M). 452 formulated at 30% (wt/wt%) was an extremely robust SDD that was able to withstand 40°C 75%RH open storage conditions for 6 months with no physical evidence of crystallization or loss of dissolution performance...
January 9, 2017: Molecular Pharmaceutics
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