keyword
https://read.qxmd.com/read/32454119/endosome-triggered-ion-releasing-nanoparticles-as-therapeutics-to-enhance-the-angiogenic-efficacy-of-human-mesenchymal-stem-cells
#21
JOURNAL ARTICLE
Gwang-Bum Im, Euiyoung Jung, Yeong Hwan Kim, Yu-Jin Kim, Sung-Won Kim, Gun-Jae Jeong, Tae-Jin Lee, Dong-Ik Kim, Jinheung Kim, Taeghwan Hyeon, Taekyung Yu, Suk Ho Bhang
Here, we report that Fe ions delivered into human mesenchymal stem cells (hMSCs) by bioreducible metal nanoparticles (NPs) enhance their angiogenic and cell-homing efficacy by controlling ion-triggered intracellular reactive oxygen species (ROS) and improve cell migration, while reducing cytotoxicity. Endosome-triggered iron-ion-releasing nanoparticles (ETIN) were designed to be low-pH responsive to take advantage of the low-pH conditions (4-5) of endosomes for in situ iron-ion release. Due to the different redox potentials of Fe and Au, only Fe could be ionized and released from our novel ETIN, while Au remained intact after ETIN endocytosis...
August 10, 2020: Journal of Controlled Release
https://read.qxmd.com/read/32376609/ioct-assisted-macular-hole-surgery-outcomes-and-utility-from-the-discover-study
#22
JOURNAL ARTICLE
Philina Yee, Duriye Damla Sevgi, Joseph Abraham, Sunil K Srivastava, Thuy Le, Atsuro Uchida, Natalia Figueiredo, Aleksandra V Rachitskaya, Sumit Sharma, Jamie Reese, Justis P Ehlers
BACKGROUND/AIMS: This study aimed to characterise the clinical outcomes and utility of intraoperative optical coherence tomography (iOCT)-assisted macular hole (MH) repair. METHODS: This was a post hoc analysis of eyes in the D etermination of feasibility of I ntraoperative S pectral domain microscope C ombined/integrated O CT V isualization during E n face R etinal and ophthalmic surgery (DISCOVER) study undergoing surgical MH repair with use of iOCT. Functional and surgical outcome data were collected through 12 months postoperatively...
March 2021: British Journal of Ophthalmology
https://read.qxmd.com/read/31889828/the-beneficial-effect-of-indonesian-propolis-wax-from-tetragonula-sp-as-a-therapy-in-limited-vaginal-candidiasis-patients
#23
JOURNAL ARTICLE
Siti Farida, Muhamad Sahlan, Etin Rohmatin, Robiatul Adawiyah
Vaginal candidiasis characterized by abnormal vaginal discharge and itching usually treated by azole's drug or nystatin; however, some results of treatment are unsatisfied and become recurrent. Propolis containing polyphenols and flavonoids is known to have anti-inflammatory and antimicrobial activity. This study investigated the effect of Indonesian propolis wax from Tetragonula sp. as a therapy in limited vaginal candidiasis patients. The subjects were women who came to the Tasik Community Health Centre met the inclusion criteria such as clinical complaint and laboratory evaluation (positive hyphae/pseudohyphae and culture on Sabouraud Dextrose Agar (SDA) medium) from a vaginal swab...
January 2020: Saudi Journal of Biological Sciences
https://read.qxmd.com/read/27708908/a-case-of-neutrophilic-dermatosis-who-develop-palpable-purpura-during-the-use-of-montelukast
#24
JOURNAL ARTICLE
Gözde Yıldırım Çetin, Hayriye Sayarlıoğlu, Çiğdem Erhan, Hasan Kahraman, Harun Cıralık, Mehmet Sayarlıoğlu
In this case report, we present a female patient with neutrophilic dermatosis (ND) occurring as palpable purpura after using montelukast. Neutrophilic dermatoses (NDs) are characterized by skin lesions in which mature neutrophils are predominantly located in the epidermis and dermis in the absence of any infective pathology. Classification of the NDs is based upon the recognition of clinical and pathologic features, as well as the identification of associated diseases, like Sweet's syndrome, pyoderma gangrenosum, generalized pustular psoriasis, and Behçet's disease...
December 2014: European Journal of Rheumatology
https://read.qxmd.com/read/27708871/herpetic-whitlow-during-immunosuppressive-therapy-for-wegener-s-granulomatosis
#25
JOURNAL ARTICLE
Dilek Solmaz, Ezgi Atalay, Banu Lebe, Pınar Çetin
Skin involvement may occur in patients with Wegener's granulomatosis (polyangiitis with granulomatosis; WG) and is more frequent in the generalised form. However, when a patient with vasculitis develops digital ulceration, in addition to disease activation, other pathologies should be considered. One of them may be the herpetic whitlow mimicking paronychia. Here, we present a patient who developed herpetic whitlow during the course of immunosuppressive therapy due to WG. Just before the third course of cyclophosphamide therapy, she was re-admitted to the outpatient clinic with the above-mentioned ulcerated lesions...
March 2014: European Journal of Rheumatology
https://read.qxmd.com/read/27695558/delayed-intracerebellar-hemorrhage-secondary-to-lumboperitoneal-shunt-insertion
#26
Uygur Er, Çetin Akyol, Murad Bavbek
Aim of this paper is to present and discuss a case of a delayed cerebellar parenchymal hemorrhage developing after L/P shunt placement with a NPH patient. A hypertensive patient admitted to our clinic with a diagnosis of NPH. The patient was placed a pressure adjustable L/P shunt without any surgical complication. He was discharged with an uneventful period. The patient was admitted to the emergency clinic of our hospital with a 1.5 × 1.5 cm diameter hematoma at the left cerebellar hemisphere on 2 days after his discharge...
October 2016: Asian Journal of Neurosurgery
https://read.qxmd.com/read/27668898/antimicrobial-susceptibility-against-penicillin-ampicillin-and-vancomycin-of-viridans-group-streptococcus-in-oral-microbiota-of-patients-at-risk-of-infective-endocarditis
#27
JOURNAL ARTICLE
Serap Süzük, Banu Kaşkatepe, Mustafa Çetin
The viridans group Streptococci (VGS) are most abundant in the mouth; in some instances they might emerge as pathogens particularly in infective endocarditis (IE). In this study, we aimed to define and determine the susceptibility against antibiotics of VGS that are members of the oral microbiota of patients exhibiting a risk of developing IE. Forty-nine patients at risk of infective endocarditis were included in the study. Identification of the bacteria was performed using API STREP (bioMérieux, France). Gradient test strips (E-Test, France) were used to determine MIC of the bacteria against penicillin, ampicillin, and vancomycin...
September 1, 2016: Le Infezioni in Medicina
https://read.qxmd.com/read/27665339/case-images-massive-liver-hematoma-secondary-to-overdose-of-warfarin-treatment
#28
JOURNAL ARTICLE
Çetin Geçmen, Muzaffer Kahyaoğlu, Ecem Yanık, Mesut Alp Karataş, İbrahim Akın İzgi
No abstract text is available yet for this article.
September 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://read.qxmd.com/read/27665330/physical-inactivity-and-low-quality-of-life-of-turkish-women-after-hospitalization-for-coronary-heart-disease-inferences-from-euroaspire-iii
#29
JOURNAL ARTICLE
Lale Tokgözoğlu, Sercan Okutucu, Ergun Barış Kaya, Çetin Erol, Oktay Ergene
OBJECTIVE: The present objective was to compare changes in lifestyle between (i) Turkish women and Turkish men, and (ii) Turkish women and European women, after hospitalization for coronary heart disease (CHD). Risk factor management, physical activity, mood, and quality of life (QOL) indices were compared. METHODS: A total of 2268 women (25.3% of 8966 patients, mean age: 65.8±9.0 years) were interviewed using the European Action on Secondary and Primary Prevention by Intervention to Reduce Events III (EUROASPIRE III)...
September 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://read.qxmd.com/read/27662457/status-epilepticus-associated-with-risperidone-and-methylphenidate-in-an-adolescent-with-epilepsy-a-case-report
#30
JOURNAL ARTICLE
Ozalp Ekinci, Halenur Teke, Sevgi Çiçek, Serkan Güneş, Çetin Okuyaz
No abstract text is available yet for this article.
December 2016: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/27656513/urethral-coitus-in-a-case-of-vaginal-agenesis-is-only-vaginoplasty-enough-to-treat-the-urinary-problems
#31
Mustafa Gazi Uçar, Tolgay Tuyan Ilhan, Ayse Gül Kebapçilar, Zekeriya Tosun, Çetin Çelik
Urethral coitus is an extremely rare condition. Megalourethra and urinary incontinence due to urethral coitus in vaginal agenesis are unusual manifestations because these patients usually present with primary amenorrhea before becoming sexually active and receive treatment. A 24-year-old woman came to our clinic because of primary amenorrhea, sexual dysfunction, dyspareunia, megalourethra and urinary incontinence five months after her marriage due to urethral coitus. Based on these clinical and radiological findings a diagnosis of Mayer-Rokitansky-Kuster-Hauser Syndrome was made and patient underwent modified McIndoe Vaginoplasty...
August 2016: Journal of Clinical and Diagnostic Research: JCDR
https://read.qxmd.com/read/27645762/relation-between-end-procedural-activated-clotting-time-values-and-radial-artery-occlusion-rate-with-standard-fixed-dose-heparin-after-transradial-cardiac-catheterization
#32
JOURNAL ARTICLE
Orhan Maden, Habibe Kafes, Kevser Gülcihan Balci, Muharrem Tola, Mehmet Timur Selçuk, Cengiz Burak, Elif Hande Çetin, Hatice Selçuk, Mustafa Mücahit Balci, Halil Lütfü Kısacık
Although heparin administration has reduced the incidence of radial artery occlusion (RAO) during the transradial coronary angiography (TRCA), the effective activated clotting time (ACT) value for guiding unfractionated heparin dosing in patients undergoing TRCA is unknown. Four hundred thirty-two patients who were scheduled for elective TRCA were enrolled in our prospective study. All the patients received a standard dose of 5,000 IU unfractionated heparin. Anticoagulation level was assessed by ACT measurements that were taken at the end of the procedure just before the sheath removal...
November 15, 2016: American Journal of Cardiology
https://read.qxmd.com/read/27626144/oxidative-stress-of-crystalline-lens-in-rat-menopausal-model
#33
JOURNAL ARTICLE
Semra Acer, Gökhan Pekel, Vural Küçükatay, Aysun Karabulut, Ramazan Yağcı, Ebru Nevin Çetin, Şahika Pınar Akyer, Barbaros Şahin
PURPOSE: To evaluate lenticular oxidative stress in rat menopausal models. METHODS: Forty Wistar female albino rats were included in this study. A total of thirty rats underwent oophorectomy to generate a menopausal model. Ten rats that did not undergo oophorectomy formed the control group (Group 1). From the rats that underwent oophorectomy, 10 formed the menopause control group (Group 2), 10 were administered a daily injection of methylprednisolone until the end of the study (Group 3), and the remaining 10 rats were administered intraperitoneal streptozocin to induce diabetes mellitus (Group 4)...
July 2016: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/27617312/augmentation-cystoplasty-in-neurogenic-bladder
#34
REVIEW
Bülent Çetinel, Ervin Kocjancic, Çetin Demirdağ
The aim of this review is to update the indications, contraindications, technique, complications, and the tissue engineering approaches of augmentation cystoplasty (AC) in patients with neurogenic bladder. PubMed/MEDLINE was searched for the keywords "augmentation cystoplasty," "neurogenic bladder," and "bladder augmentation." Additional relevant literature was determined by examining the reference lists of articles identified through the search. The update review of of the indications, contraindications, technique, outcome, complications, and tissue engineering approaches of AC in patients with neurogenic bladder is presented...
September 2016: Investigative and Clinical Urology
https://read.qxmd.com/read/27612212/sexual-functioning-before-and-after-vaginal-hysterectomy-to-treat-pelvic-organ-prolapse-and-the-effects-of-vaginal-cuff-closure-techniques-a-prospective-randomised-study
#35
RANDOMIZED CONTROLLED TRIAL
Mustafa Gazi Uçar, Tolgay Tuyan İlhan, Fatih Şanlıkan, Çetin Çelik
OBJECTIVE: To evaluate sexual function in women before and after vaginal hysterectomy (VH) and to compare the effects of horizontal and vertical vaginal cuff closure on sexual function. STUDY DESIGN: Women with uterine prolapse of stage 2 or higher were included to this prospective, randomized study. All patients underwent VH with McCall Culdoplasty and patients were randomized into two groups in terms of the vaginal cuff closure technique employed which is either vertically (group 1, right to left) or horizontally (group 2, anterior to posterior)...
November 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/27606132/a-comparison-of-sexual-function-psychological-status-and-sociodemographic-characteristics-of-turkish-men-within-polygamous-and-monogamous-marriages
#36
JOURNAL ARTICLE
Hasan Çetin Ekerbiçer, Sefa Resim, Erkan Efe, Mustafa Remzi Bahar, Özlem Altunören, Faruk Küçükdurmaz, Can Benlioğlu
BACKGROUND: A limited number of studies within the literature have entailed objective evaluations of psychological, sexual, and emotional features of women within polygamous marriages. However, there is a lack of studies reporting these features among polygamous and monogamous men. AIMS: The aim of this study was to investigate sociodemographic characteristics, sexual function, and psychological status of polygamously and monogamously married men. STUDY DESIGN: Cross-sectional study...
July 2016: Balkan Medical Journal
https://read.qxmd.com/read/27598592/ingested-intraabdominal-foreign-bodies-that-require-surgical-intervention
#37
JOURNAL ARTICLE
Remzi Kızıltan, Özkan Yılmaz, Abbas Aras, Osman Toktaş, Abdulsamet Batur, Fatma Ağar, Şehmus Ölmez, Çetin Kotan
BACKGROUND: The aim of the present study was to review cases that required surgical intervention to remove ingested foreign bodies. METHODS: Medical records of 7 patients who underwent surgical intervention at the Yüzüncü Yıl University Department of General Surgery between 2009 and 2014 after ingesting foreign bodies were reviewed. RESULTS: Female:male ratio was 5:2; mean age was 25 (16-35). Four patients had swallowed pins, 1 patient had swallowed a sewing pin, 1 patient had swallowed a safety pin, and 1 patient had swallowed a wristwatch...
May 2016: Turkish Journal of Trauma & Emergency Surgery: TJTES
https://read.qxmd.com/read/27593787/nerve-tissue-prefabrication-inside-the-rat-femoral-bone-does-it-work
#38
JOURNAL ARTICLE
Zuhtu Ozbek, Atacan Emre Kocman, Orhan Ozatik, Erdem Soztutar, Emre Ozkara, Aydan Kose, Ali Arslantas, Cengiz Cetin
AIM: To investigate whether nerve regeneration can be induced in the tubular bone between distal and proximal cut nerve ends. MATERIAL AND METHODS: Twenty adult Wistar rats were used for the study. Rats were divided into three groups; femoral bone conduit group, nerve transection group, sham group. The sciatic nerve was surgically cut and from both ends inserted into the adjacent femoral bone tunnel in the femoral bone conduit group. The sciatic nerve was cut transversely in the nerve transection group...
2017: Turkish Neurosurgery
https://read.qxmd.com/read/27572511/application-of-high-resolution-melting-analysis-for-differentiation-of-spoilage-yeasts
#39
JOURNAL ARTICLE
Mine Erdem, Zülal Kesmen, Esra Özbekar, Bülent Çetin, Hasan Yetim
A new method based on high resolution melting (HRM) analysis was developed for the differentiation and classification of the yeast species that cause food spoilage. A total 134 strains belonging to 21 different yeast species were examined to evaluate the discriminative power of HRM analysis. Two different highly variable DNA regions on the 26 rRNA gene were targeted to produce the HRM profiles of each strain. HRM-based grouping was compared and confirmed by (GTG)5 rep-PCR fingerprinting analysis. All of the yeast species belonging to the genera Pichia, Candida, Kazachstania, Kluyveromyces, Debaryomyces, Dekkera, Saccharomyces, Torulaspora, Ustilago, and Yarrowia, which were produced as species-specific HRM profiles, allowed discrimination at species and/or strain level...
September 2016: Journal of Microbiology / the Microbiological Society of Korea
https://read.qxmd.com/read/27571117/focal-nodulary-hyperplasia-of-the-liver-due-to-congenital-portosystemic-shunt-a-rare-condition-mimicking-hepatocellulary-carcinoma
#40
JOURNAL ARTICLE
Arzu Yazal Erdem, Suna Emir, Haci A Demir, Derya Özyörük, İlker Çetin, Aynur Turan, Esra Karakuş
Congenital portosystemic shunts are rare vascular malformations that lead to several complications including liver tumors, pulmonary hypertension, and metabolic encephalopathy. We describe a rare case of a 17-year-old girl with an extrahepatic portosystemic shunt presenting recurrent syncope episodes and a liver mass mimicking hepatocellulary carcinoma.
January 2017: Journal of Pediatric Hematology/oncology
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