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axillar nodes lymphatic

Takaaki Fujii, Reina Yajima, Hiroki Morita, Satoru Yamaguchi, Soichi Tsutsumi, Takayuki Asao, Hiroyuki Kuwano
BACKGROUND: Schwannoma is a tumor that develops on peripheral nerves or spinal roots. Although any part of the body can be affected, axillar and supraclavicular lesions are unusual for schwannoma. We report two cases of schwannoma arising in the brachial plexus, which were detected by 18F-fluorodeoxyglucose positron emission tomography and computed tomography (FDG-PET/CT). CASE 1: A 75-year-old Japanese woman showed high FDG accumulation in a subclavicular or axillary lesion found by FDG-PET/CT...
2014: World Journal of Surgical Oncology
Adam Adam Maciejczyk
For many years, the age of the patient, the condition of axillar lymph nodes, the size of the tumour, histological traits (in particular histological grade of malignancy and invasion of lymphatic vessels), condition of hormonal receptors and HER2 represented principal factors used for the stratification of breast cancer patients for the purposes of evaluating the prognosis and determining the appropriate strategy of treatment. Although the variables are useful for the prognostic evaluation of individual groups of breast cancer patients, their role in determining the individual risk level of the patient and in the selection of supplementary treatment is quite restricted...
January 2013: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Toplica Bojić, Nebojsa Djordjević, Aleksandar Karanikolić, Sladjana Filipović, Miroslav Granić, Antigoni A Poultsidi
BACKGROUND/AIM: There are a lot of studies aiding to the opinion that the involvement degree of axilla lymph nodes grows depending on increase of breast tumor size, and its histological and nuclear grades. The aim of this study was to assess the risk of axillary lymph nodes involvement, as well as the relation between the tumor size, histological and nuclear grades in a group of female patients who underwent breast cancer surgery, including levels 1-3 axillary dissection. METHODS: Investigationcovered 900 patients operated on during 2005-2008 who underwent modified radical mastectomy including axillar dissection...
May 2012: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
Johanna Hynninen, Annika Auranen, Olli Carpén, Kirsti Dean, Marko Seppänen, Jukka Kemppainen, Maija Lavonius, Irina Lisinen, Johanna Virtanen, Seija Grénman
OBJECTIVE: Epithelial ovarian cancer (EOC) spreads intra-abdominally and to the retroperitoneal lymph nodes. A greater number of distant metastases are revealed by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) compared to conventional imaging methods. We aimed to investigate the presence and anatomic distribution of supradiaphragmatic lymph node metastasis (LNM) detected with pretreatment FDG PET/CT. METHODS: Thirty women with advanced stage (IIC-IV) EOC were scanned with whole body contrast-enhanced FDG PET/CT prior to surgery/neoadjuvant chemotherapy...
July 2012: Gynecologic Oncology
Fumiki Toriumi, Shigenori Ei, Hidena Takahashi, Rei Okada, Kyohei Masai, Mikiko Mito, Naoki Ishimaru, Katsuhiko Mizuno, Kan Handa, Takahiro Yamanashi, Yoshitomo Koshida, Hidetoshi Akamatsu, Katsuhiko Motegi, Toshihide Tajima, Kiyoshi Mukai, Yutaka Shimoyama
A59 -year-old woman was referred to our hospital for a close examination and treatment of an advanced gastric carcinoma. A physical examination and CT scan showed that the right cervical and axillar lymph nodes were swelling, and a histopathological examination of the axillar lymph node revealed metastatic growth of the gastric carcinoma (Stage IV). Then, we started S-1/CDDP combination chemotherapy. S-1 (80 mg/m2/day)was orally administered for 3 weeks followed by 2 weeks of rest, and CDDP (60 mg/m2) was administered by drip on day 8...
July 2011: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Noriyuki Watanabe, Takashi Iwazawa, Tomohiro Kitahara, Takehiro Yanagawa, Koji Munakata, Kaori Takamoto, Kenichi Nagai, Masakazu Miyake, Taishi Hata, Kenshu Kawanishi, Junzo Shimizu, Kimimasa Ikeda, Jyunya Fujita, Kenzou Akagi, Keizou Dono, Masashi Kitada, Nobuyuki Takimoto, Kinya Abe, Shiro Adachi, Takashi Shimano
A 41-year-old man who had non-small cell lung cancer invading his right 3rd, 4th and 5th ribs with hilum lymph node swelling(cT3N1M0, cStage III A), received chemoradiation therapy, cisplatin(CDDP)/docetaxel, and 2 Gy/Fr of irradiation prior to surgery. But the therapy was discontinued due to interstitial pneumonitis on day 24, during 28 Gy of radiation. At that time, a PET-CT scan revealed the accumulation of FDG in the primary tumor, hilar lymph node, and one of the ipsilateral axillar lymph nodes, in which cancer cell presence was proven by aspiration needle cytology...
June 2011: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Norihisa Hanada, Nariaki Tomiyama, Kazuki Hori, Shuichi Kusano, Yasushi Yoshida, Kosei Kawata, Ryojin Uchino, Naomi Sakashita
We report a case of recurrent breast cancer with solitary lung metastasis that has shown no recurrence with treatment by trastuzumab alone after partial resection of the right lung upper lobe. A 56-year-old woman, who presented with left breast cancer, underwent quadrantectomy and axillar lymph node dissection in March 2004. Pathological findings were as follows: invasive ductal carcinoma, 3. 7 cm in size, histological grade 3, positive invasion of lymphatic and blood vessels, negative nodal status, negative ER/PgR status, and overexpression of HER2/ neu...
December 2010: Gan to Kagaku Ryoho. Cancer & Chemotherapy
T Deliĭski
The development of sentinel lymph nodes biopsy rouses a newer interest to internal mammary lymph nodes region. We report a case of internal mammary sentinel lymph nodes biopsy of a woman with breast cancer leaded to stage migration. A 71 years old woman with upper medial quadrant left breast cancer is reported. The tumor is 2.5 cm in size. Marking of SLN with radionuclide (Tc99m) and with 2 dyes (Patent blue V and Indocyanin green) are done. Only internal mammary lymph node is established with lymphoscintigrapgy...
2005: Khirurgiia
D Oertli
Axillary dissection aims at local tumor control and staging. Among breast cancer, malignant melanoma and other solid malignancies, the nodal status is still the most important predictive and prognostic factor. Today, because of its morbidity, axillary lymphadenectomy is indicated only when the sentinel lymph node is involved by metastasis after histopathologic investigation. The surgical technique of axillary dissection is presented, complications and oncologic outcomes are summarised after dissection for breast carcinoma and malignant melanoma, respectively...
March 2007: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Oliver Albores-Zúñiga, Alejandro-Eduardo Padilla-Rosciano, Héctor Martínez-Said, Mario Cuéllar-Hubbe, Julio Ramírez-Bollas
The procedure of sentinel node biopsy has been used previously in clear cell sarcoma. There are few studies reported. Due to the similar biological features with melanoma, this procedure can be effective. Sentinel biopsy is an option to detect nodal subclinical metastases. A 19-year-old man presented with ulcerated lesion in the fifth finger of the left hand. The biopsy reported clear cell sarcoma. Immunohistochemistry was positive for Vimentin and S-100. There was no evidence of regional disease. The sentinel lymph node biopsy, using patent blue and Tc-99 rhenium, was positive for metastases...
March 2006: Cirugia y Cirujanos
I Blanco Sáiz, C Moriyón Entrialgo, R Gómez Barquín, M A Díez Esteban, D Platero García, J Pelletán Fernández, R Alvarez Obregón, F J Aira Delgado
Traditional lymphadenectomy is being replaced by sentinel node biopsy in initial management of early stage breast cancer. The aim of this study was to validate the technique in our center, where we perform preoperative lymphoscintigraphy and intraoperative detection of sentinel node, after periareolar radiotracer and peritumoral blue dye injection. Sixty patients, breast cancer stages I and II, were included. Lymphatic mapping was performed the day before surgery, after the administration of 74 MBq 99mTc sulfur colloid in periareolar subdermal tissue...
March 2004: Revista Española de Medicina Nuclear
V F Semiglazov, S Ia Maksimov, V V Semiglazov, A G Kosnikov
The results of organ-sparing treatment of patients with cancers of the breast, uterine cervix, endometrium and ovary are described in the paper. A prospective randomized clinical study launched in 1995 at Petrov's Research Institute of Oncology comprised cases of above 700 patients with breast cancer, around 300 women with cancer in situ and with microinvasive cancer of the uterine cervix and 83 patients with initial endometrial cancer. The results of the above treatment (segment resection + axillar dissection + radiotherapy) were shown to be similar to those obtained after Petey-Dyson mastectomy (5-year survival of 86...
2003: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
Mafalda A Videira, M F Botelho, Ana C Santos, Luis F Gouveia, J J Pedroso de Lima, António J Almeida
UNLABELLED: Lymphatic drainage plays an important role in the uptake of particulates in the respiratory system, being also associated to the spreading of lung cancer through metastasis development. In recent years solid lipid nanoparticles (SLN) have been proposed as carriers of anti-tumoural drugs, for their low toxicity and surface characteristics make them suitable for either imaging (gamma-scintigraphy) or therapy upon encapsulation of cytotoxic drugs. Assessment of inhaled radiolabelled SLN biodistribution is described in the present work...
December 2002: Journal of Drug Targeting
A Kh Ismagilov, E I Sigal, A M Gimranov
Comparative analysis of the results of videothoracoscopic parasternal lymphadenectomy and standard mastectomy by Urban--Holdin is presented. In November 1995 to December 1999 205 videothoracoscopic parasternal lymphadenectomies were performed (96--on the left, 104--on the right). Central and medial location of breast cancer was indication for this operation. Age of the patients ranged from 23 to 73 years. Surgery was performed under intravenous anesthesia in the conditions of artificial lung ventilation with separate lung intubation...
2001: Khirurgiia
R S Amparo, C D Angel, L H Ana, L C Antonio, M S Vicente, F M Carlos, G P Vicente
Inflammatory breast carcinoma (IBC) diagnosis is usually based in the presence of typical clinical symptoms (redness and edema in more than 2/3 of the breast), which are not always associated with pathologic characteristics (subdermal lymphatics involvement). Whether exclusively pathologic findings without clinical symptoms are sufficient for IBC diagnosis remains controversial. A retrospective analysis of 163 clinically diagnosed IBC (CIC) either with dermal lymphatics invasion or not, was compared with another group of 99 patients with dermal lymphatics invasion without clinical symptoms (occult inflammatory carcinoma) (OIC)...
December 2000: Breast Cancer Research and Treatment
K Motomura, S Noguchi, H Inaji, H Koyama
The main therapy for primary breast cancer is not surgery, but a systemic therapy involving administration of cytotoxic chemotherapy or the use of ablative or additive endocrine therapy to control disseminated micrometastasis. The results of randomized trials and meta-analysis show that CMF, the standard adjuvant chemotherapy, is effective regardless of axillar lymph node involvement or menopausal status. Effectiveness of adjuvant chemotherapy with an anthracyclin-based regimen remains controversial. The trial by CUBC and NSAS-BC comparing UFT, widely used in the management of patients with breast cancer in Japan, with CMF is on-going...
August 1997: Gan to Kagaku Ryoho. Cancer & Chemotherapy
K Kishimoto, T Sakata, K Itoh, K Tominaga, H Ino, I Murohashi, I Jinnai, M Bessho, H Takeuchi, M Saitoh, K Hirashima
We reported a 59-year-old woman who received a diagnosis of psoriasis vulgaris at the age of 35 and had been under medical treatment. She was admitted to our department on August 16, 1993 because of lymphadenopathy, arthralgia and neuralgia. We observed cervical and axillar lymphadenopathy 1-3 cm in diameter, anemia and leukothrombocytosis. Elevated levels of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and immunoglobulin G (IgG), but not M-protein were observed by immunological analysis of the serum...
February 1997: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
Y Ohta, Y Watanabe, T Tabata, M Oda, Y Hayashi, Y Endo, M Tanaka, T Sasaki
We assessed the inhibitory action of TNP-470 on lymph node metastasis in a metastatic model system using athymic nude mice. Mice were injected subcutaneously with 5 x 10(6) HT-1080 cells in the right groin. TNP-470 (10, 30 and 100 mg kg-1) was injected subcutaneously nine times in total every other day from the 7th day after tumour inoculation. Axillar and inguinal lymph nodes were dissected, and DNA was extracted 5 weeks after tumour inoculation. Specific detection of a human beta-globin-related sequence in metastasized human tumour cells in nude mice was done by the polymerase chain reaction (PCR) technique and analysed by Southern blotting...
1997: British Journal of Cancer
M Numata, M Nishikawa, M Kudo, T Kaneko, H Ikeda, T Okubo, Y Rino, H Kitamura
A 31-year-old woman was admitted to our hospital because of cervical and axillar lymph node swelling. A chest X-ray film showed many nodular shadows and a cavity in the left upper lung field. The tuberculin test was positive. Transbronchial lung biopsy and cervical lymph node biopsy were done. Examination of the biopsy specimens revealed epithelial granulomas with caseous necrosis. Thus, pulmonary tuberculosis with systemic lymph node swelling was diagnosed. Examinations during the patient's hospital stay showed that she was not an immunocompromised host...
November 1995: Nihon Kyōbu Shikkan Gakkai Zasshi
G V Turner, J van Niekerk
The lymph drainage of the major joints of the porcine forelimb was subjected to a critical examination. Commercial India ink was injected into the left elbow joint and right shoulder joint of an experimental pig. The shoulder joint was approached craniolaterally, the injection site being at the cranial border of the tendon of insertion of the infraspinatus muscle. The elbow joint was approached from the dorsolateral aspect. A suitable site for intra-articular injection into the elbow joint was found to be within an imaginary triangle formed caudal to the lateral epicondyloid crest of the humerus, the ventral border of the lateral head of the M...
September 1980: Journal of the South African Veterinary Association
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