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https://www.readbyqxmd.com/read/28920521/implementing-evidence-based-smoking-cessation-treatment-in-psychosocial-care-units-caps-in-brazil
#1
João Mauricio Castaldelli-Maia, Nilson R da Silva, Marta Rd Campos, Helena F Moura, Gustavo Zabert, Beatriz M Champagne, Katherine E Kemper, J Taylor Hays
BACKGROUND: The prevalence of smoking among mental health and addiction (MHA) patients is 3 times higher than it is in the general population, yet this patient population has received little help to combat smoking. Considering this, psychosocial care centers (CAPS - Centros de Atenção Psicossocial) are strategic locations for integrating tobacco dependence treatment (TDT) into existing treatment activities. METHODS: Our team provided an 8-hour training package to the staff of CAPS that have not been providing specialized TDT for smokers...
September 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28918974/pigmentary-changes-in-patients-treated-with-targeted-anticancer-agents-a-systematic-review-and-meta-analysis
#2
Julia Dai, Viswanath R Belum, Shenhong Wu, Vincent Sibaud, Mario E Lacouture
BACKGROUND: The discovery of signaling networks that drive oncogenic processes has led to the development of targeted anticancer agents. The burden of pigmentary adverse events from these drugs is unknown. OBJECTIVE: To conduct a systematic review and meta-analysis of published clinical trials and determine the incidence and risk of development of targeted therapy-induced pigmentary changes. METHODS: A comprehensive search was conducted to identify studies reporting targeted therapy-induced pigmentary changes...
September 14, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28916976/preoperative-risk-factors-for-postoperative-complications-in-endoscopic-pituitary-surgery-a-systematic-review
#3
REVIEW
Daniel J Lobatto, Friso de Vries, Amir H Zamanipoor Najafabadi, Alberto M Pereira, Wilco C Peul, Thea P M Vliet Vlieland, Nienke R Biermasz, Wouter R van Furth
BACKGROUND: The ability to preoperatively predict postoperative complication risks is valuable for individual counseling and (post)operative planning, e.g. to select low-risk patients eligible for short stay surgery or those with higher risks requiring special attention. These risks however, are not well established in pituitary surgery. METHODS: We conducted a systematic review of associations between preoperative characteristics and postoperative complications of endoscopic transsphenoidal surgery according to the PRISMA guidelines...
September 15, 2017: Pituitary
https://www.readbyqxmd.com/read/28912512/assessing-individual-risk-for-amd-with-genetic-counseling-family-history-and-genetic-testing
#4
R Cascella, C Strafella, G Longo, L Manzo, M Ragazzo, C De Felici, S Gambardella, L T Marsella, G Novelli, P Borgiani, F Sangiuolo, A Cusumano, F Ricci, E Giardina
PurposeThe goal was to develop a simple model for predicting the individual risk profile for age-related macular degeneration (AMD) on the basis of genetic information, disease family history, and smoking habits.Patients and methodsThe study enrolled 151 AMD patients following specific clinical and environmental inclusion criteria: age >55 years, positive family history for AMD, presence of at least one first-degree relative affected by AMD, and smoking habits. All of the samples were genotyped for rs1061170 (CFH) and rs10490924 (ARMS2) with a TaqMan assay, using a 7500 Fast Real Time PCR device...
September 15, 2017: Eye
https://www.readbyqxmd.com/read/28912285/predictors-of-incomplete-occlusion-following-pipeline-embolization-of-intracranial-aneurysms-is-it-less-effective-in-older-patients
#5
N Adeeb, J M Moore, M Wirtz, C J Griessenauer, P M Foreman, H Shallwani, R Gupta, A A Dmytriw, R Motiei-Langroudi, A Alturki, M R Harrigan, A H Siddiqui, E I Levy, A J Thomas, C S Ogilvy
BACKGROUND AND PURPOSE: Flow diversion with the Pipeline Embolization Device (PED) for the treatment of intracranial aneurysms is associated with a high rate of aneurysm occlusion. However, clinical and radiographic predictors of incomplete aneurysm occlusion are poorly defined. In this study, predictors of incomplete occlusion at last angiographic follow-up after PED treatment were assessed. MATERIALS AND METHODS: A retrospective analysis of consecutive aneurysms treated with the PED between 2009 and 2016, at 3 academic institutions in the United States, was performed...
September 14, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28891084/structured-advice-provided-by-a-dietitian-increases-adherence-of-consumers-to-diet-and-lifestyle-changes-and-lowers-blood-low-density-lipoprotein-ldl-cholesterol-the-increasing-adherence-of-consumers-to-diet-lifestyle-changes-to-lower-ldl-cholesterol-act-randomised
#6
T E Sialvera, A Papadopoulou, S P Efstathiou, E A Trautwein, R T Ras, N Kollia, P Farajian, G Goumas, I Dimakopoulos, K Papavasiliou, A Koutsouri, A Zampelas
BACKGROUND: Evidence from healthcare professionals suggest that consumer compliance to healthy diet and lifestyle changes is often poor. The present study investigated the effect of advice provided by a physician or dietitian on consumer adherence to these measures combined with consuming foods with added plant sterols (PS) with the aim of lowering low-density lipoprotein cholesterol (LDL-C). METHODS: One hundred mildly-to-moderately hypercholesterolaemic individuals were enrolled into a parallel, randomised, placebo-controlled study...
September 11, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28889454/intrafamilial-variability-of-the-triphalangeal-thumb-phenotype-in-a-dutch-population-evidence-for-phenotypic-progression-over-generations
#7
Martijn Baas, Jacob W P Potuijt, Steven E R Hovius, A Jeannette M Hoogeboom, Robert-Jan H Galjaard, Christianne A van Nieuwenhoven
Triphalangeal thumbs (TPTs) are regularly caused by mutations in the ZRS in LMBR1. Phenotypic variability can be present in TPT-families. However, recent observations suggest an increased occurrence of severe phenotypes in the Dutch TPT-population. Therefore, the aim of this study is to investigate the progression of the clinical severity of TPT-phenotype through generations. Index patients from a Dutch TPT-population were identified. A 105C>G mutation in the ZRS has previously been confirmed in this population...
September 10, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28885481/comparison-of-an-electromagnetic-middle-ear-implant-and-hearing-aid-word-recognition-performance-to-word-recognition-performance-obtained-under-earphones
#8
C Y Joseph Chang, Michael Spearman, Brian Spearman, Anna McCraney, Michael E Glasscock
OBJECTIVE: To report the results of patients with the Maxum middle ear implant (MEI) and compare word recognition scores (WRS) and speech perception gap (SP Gap) of Maxum versus optimally fit hearing aids (HA). STUDY DESIGN: Case series with chart review. SETTING: Single, private otology clinic. PATIENTS: Eleven ears, in nine adult patients (two women; average age 62.7 yr). INTERVENTIONS: Twelve consecutive ears with moderate to severe sensorineural hearing loss (SNHL) underwent implantation of the Maxum system...
October 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28884902/the-role-of-elimination-diets-in-atopic-dermatitis-a-comprehensive-review
#9
REVIEW
Neil R Lim, Mary E Lohman, Peter A Lio
BACKGROUND/OBJECTIVES: Diet is a common concern for individuals with atopic dermatitis (AD) and their families. Studies regarding the effect of dietary interventions on AD exist, but many are limited by small size and poor design. Conflicting results present a challenge to clinicians seeking to counsel patients. The aim of the current review is to examine the published literature and generate helpful conclusions for clinicians faced with dietary questions in AD. METHODS: A PubMed search was performed focusing on dietary interventions for AD in children and adults through July 2016...
September 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28878660/long-term-progression-of-sensorineural-hearing-loss-and-tinnitus-after-combined-intensity-modulated-radiation-therapy-and-cisplatin-based-chemotherapy-for-nasopharyngeal-carcinoma-a-case-report
#10
Ming S Lee, Sudha Penumala, Steven Sweet, Russell R De Luca, Ariel E Stearnes, Yamac Akgun
Sensorineural hearing loss (SNHL) is a common adverse effect for nasopharyngeal carcinoma (NPC) patients treated with chemoradiotherapy. We report a case of 12-year follow-up from a patient with stage IIB NPC, treated in 2004 with intensity-modulated radiotherapy and cisplatin-based chemotherapy. Pure-tone audiograms were conducted before treatment and at two other points in the 12-year period after treatment. Analysis of the patient's audiograms reveals that the development of high-frequency SNHL started after treatment and reached a plateau accompanied by tinnitus approximately 32 months after treatment conclusion...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28857498/self-regulatory-efficacy-encourages-exercise-persistence-despite-arthritis-flare-symptoms
#11
James D Sessford, Lawrence R Brawley, Miranda A Cary, Parminder K Flora, Jocelyn E Blouin, Laura Meade, Shaelyn M Strachan, Nancy C Gyurcsik
BACKGROUND: The study of exercise adherence during an arthritis flare is recommended by arthritis researchers. Studies to date have been correlational. METHODS: Social cognitions of exercising individuals with arthritis who consider exercise adherence under different levels of challenge of an arthritis flare were examined using an experimental design. Exercising individuals with differential self-regulatory efficacy for managing arthritis flare symptoms (SRE-flare) were randomly assigned to conditions where flare symptoms were perceived as either many or few...
August 31, 2017: Applied Psychology. Health and Well-being
https://www.readbyqxmd.com/read/28854721/chronic-combined-hyperandrogenemia-and-western-style-diet-in-young-female-rhesus-macaques-causes-greater-metabolic-impairments-compared-to-either-treatment-alone
#12
C A True, D L Takahashi, S E Burns, E C Mishler, K R Bond, M C Wilcox, A R Calhoun, L A Bader, T A Dean, N D Ryan, O D Slayden, J L Cameron, R L Stouffer
STUDY QUESTION: Does developmental exposure to the combination of hyperandrogenemia and western-style diet (WSD) worsen adult metabolic function compared to either treatment alone? SUMMARY ANSWER: Young female rhesus macaques treated for 3 years, beginning at menarche, with combined testosterone (T) and WSD have increased weight gain and insulin resistance compared to controls and animals treated with either T or WSD alone. WHAT IS KNOWN ALREADY: Hyperandrogenemia is a well-established component of polycystic ovary syndrome (PCOS) and can be observed in peripubertal girls, indicating a potential pubertal onset of the disease...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28820185/can-lester-jones-tubes-be-tolerated-for-decades
#13
R L Scawn, D H Verity, G E Rose
PurposeLester Jones described canalicular bypass tubes 50 years ago. We present a cohort of patients with Jones' tubes first placed between 1969 and 1989, and who were reviewed within the last 15 years.Patients and methodsRetrospective case-note review for living patients identified as having had Jones' tube placement prior to 1990. The duration of Jones' tube usage was noted and the number of replacements recorded.ResultsTwenty-nine patients (33 eyes) had maintenance of their Jones' tube(s) within the last 15 years, and had first tube placement before 1990...
August 18, 2017: Eye
https://www.readbyqxmd.com/read/28817376/association-between-hospice-spending-on-patient-care-and-rates-of-hospitalization-and-medicare-expenditures-of-hospice-enrollees
#14
Melissa D Aldridge, Andrew J Epstein, Abraham A Brody, Eric J Lee, R Sean Morrison, Elizabeth H Bradley
BACKGROUND: Care at the end of life is increasingly fragmented and is characterized by multiple hospitalizations, even among patients enrolled with hospice. OBJECTIVE: To determine whether hospice spending on direct patient care (including the cost of home visits, drugs, equipment, and counseling) is associated with hospital utilization and Medicare expenditures of hospice enrollees. DESIGN: Longitudinal, observational cohort study (2008-2010)...
August 17, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28816160/the-impact-of-cardiac-radiation-dosimetry-on-survival-after-radiation-therapy-for-non-small-cell-lung-cancer
#15
S Vivekanandan, D B Landau, N Counsell, D R Warren, A Khwanda, S D Rosen, E Parsons, Y Ngai, L Farrelly, L Hughes, M A Hawkins, J D Fenwick
PURPOSE: The heart receives high radiation doses during radiation therapy of advanced-stage lung cancer. We have explored associations between overall survival, cardiac radiation doses, and electrocardiographic (ECG) changes in patients treated in IDEAL-CRT, a trial of isotoxically escalated concurrent chemoradiation delivering tumor doses of 63 to 73 Gy. METHODS AND MATERIALS: Dosimetric and survival data were analyzed for 78 patients. The whole heart, pericardium, AV node, and walls of left and right atria (LA/RA-Wall) and ventricles (LV/RV-Wall) were outlined on radiation therapy planning scans, and differential dose-volume histograms (dDVHs) were calculated...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28797715/universal-point-of-care-testing-for-lynch-syndrome-in-patients-with-upper-tract-urothelial-carcinoma
#16
Michael J Metcalfe, Firas G Petros, Priya Rao, Maureen E Mork, Lianchun Xiao, Russell R Broaddus, Surena F Matin
BACKGROUND: Patients with Lynch syndrome (LS) are at risk for upper tract urothelial carcinoma (UTUC). We aim to identify the most reliable means of point-of-care (POC) screening for LS in UTUC patients. METHODS: From January 2013 through July 2016, 115 consecutive UTUC patients without a history of LS were universally screened during their follow-up. We evaluated patient/family history (Amsterdam criteria I [AMS1] and II [AMS2]), tumor immunohistochemistry (IHC) for mismatch repair proteins (MMRP), and microsatellite instability (MSI)...
August 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28774441/a-real-time-stress-classification-system-based-on-arousal-analysis-of-the-nervous-system-by-an-f-state-machine
#17
R Martinez, E Irigoyen, A Arruti, J I Martin, J Muguerza
BACKGROUND AND OBJECTIVE: Detection and labelling of an increment in the human stress level is a contribution focused principally on improving the quality of life of people. This work is aimed to develop a biophysical real-time stress identification and classification system, analysing two noninvasive signals, the galvanic skin response and the heart rate variability. METHODS: An experimental procedure was designed and configured in order to elicit a stressful situation that is similar to those found in real cases...
September 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28756042/effectiveness-of-continuing-nicotine-replacement-after-a-lapse-a-randomized-trial
#18
John R Hughes, Laura J Solomon, Catherine E Peasley-Miklus, Peter W Callas, James R Fingar
INTRODUCTION: Four post-hoc analyses of prior trials found smokers using nicotine patch following a lapse were less likely to progress to relapse compared to those using a placebo patch following a lapse. We attempted a conceptual replication test of these results via a randomized trial of instructions to continue vs. stop nicotine patch after a lapse. METHODS: Smokers trying to quit (n=701) received nicotine patch (21/14/7mg) and brief phone counseling (six 15-min sessions)...
July 14, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28746164/implementation-of-a-novel-adherence-monitoring-strategy-in-a-phase-iii-blinded-placebo-controlled-hiv-1-prevention-clinical-trial
#19
Marla J Husnik, Elizabeth R Brown, Mark Marzinke, Edward Livant, Thesla Palanee-Phillips, Craig Hendrix, Flavia Matovu Kiweewa, Gonasagrie Nair, Lydia E Soto-Torres, Katie Schwartz, Sharon L Hillier, Jared M Baeten
BACKGROUND: Placebo-controlled HIV-1 prevention trials of pre-exposure prophylaxis (PrEP) have not generally used concurrent measurement of adherence due to the potential risk of unblinding. However, several PrEP trials for HIV-1 prevention among women failed to show effectiveness due to low product adherence. Evaluation of product adherence objectively during a study provides the opportunity for strengthening adherence activities at sites having low adherence. METHODS: During MTN-020/ASPIRE, a phase III, placebo-controlled trial of the dapivirine intravaginal ring, we implemented an adherence monitoring system...
July 24, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28734497/functional-not-chronologic-age-frailty-index-predicts-outcomes-in-advanced-ovarian-cancer
#20
Amanika Kumar, Carrie L Langstraat, Stephanie R DeJong, Michaela E McGree, Jamie N Bakkum-Gamez, Amy L Weaver, Nathan K LeBrasseur, William A Cliby
OBJECTIVES: To assess the impact of frailty as measured by a frailty deficit index (FI) on outcomes in advanced epithelial ovarian cancer (EOC) after primary debulking surgery (PDS). METHODS: Women with Stage IIIC/IV EOC who underwent PDS between 1/1/2003-12/31/2011 were included. Medical records were reviewed for patient characteristics and outcomes. The FI includes 30 items scored at 0, 0.5 or 1 and is calculated by summing across all the item scores and dividing by the total...
July 19, 2017: Gynecologic Oncology
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