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https://www.readbyqxmd.com/read/29905499/developing-nurses-skills-in-motivational-interviewing-to-promote-a-healthy-lifestyle-in-patients-with-coronary-artery-disease
#1
Jos Dobber, Corine Latour, Marjolein Snaterse, Berno van Meijel, Gerben Ter Riet, Wilma Scholte Op Reimer, Ron Peters
BACKGROUND: If nurses have the communication skills and the time, they can play an important role in increasing the intrinsic motivation of patients with coronary artery disease (CAD) to change their lifestyle. Motivational Interviewing (Mo-Int) can be used to further support this role. However, few nurses are sufficiently proficient in applying Mo-Int skills. Increasing these complex communication skills may contribute significantly to achieve lifestyle changes in CAD patients. AIMS: The aim of this study was to evaluate the coaching of nurses to skilfully use Mo-Int in a secondary prevention programme for CAD patients...
June 1, 2018: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29895966/a-dual-modality-hybrid-imaging-system-harnesses-radioluminescence-and-sound-to-reveal-molecular-pathology-of-atherosclerotic-plaques
#2
Raiyan T Zaman, Siavash Yousefi, Steven R Long, Toshinobu Saito, Michael Mandella, Zhen Qiu, Ruimin Chen, Christopher H Contag, Sanjiv S Gambhir, Frederick T Chin, Butras T Khuri-Yakub, Michael V McConnell, K Kirk Shung, Lei Xing
Atherosclerosis is a progressive inflammatory condition caused by an unstable lesion, called thin-cap fibro atheromata (TCFA) that underlies coronary artery disease (CAD)-one of the leading causes of death worldwide. Therefore, early clinical diagnosis and effective risk stratification is important for CAD management as well as preventing progression to catastrophic events. However, early detection could be difficult due to their small size, motion, obscuring 18 F-FDG uptake by adjacent myocardium, and complex morphological/biological features...
June 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29893152/ticagrelor-for-the-prevention-of-ischemic-events-in-patients-with-prior-myocardial-infarction-and-peripheral-artery-disease
#3
José C Nicolau, Luciano M Baracioli, Robert P Giugliano
Cardiovascular disease (CVD) is the main cause of death in the world. Coronary artery disease (CAD) is the most common form of CVD presentation, but the prevalence of peripheral artery disease (PAD) is increasing. Patients with polyvascular disease comprise a very high-risk population that has been infrequently studied. Areas covered: The authors review the current evidence of the efficacy and safety of ticagrelor in the setting of acute coronary syndrome and stable patients post-MI with and without PAD and summarize its pharmacokinetics, pharmacodynamics, and regulatory issues...
June 12, 2018: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29872379/hope-hybrid-drive-combining-optogenetics-pharmacology-and-electrophysiology
#4
Sebastien Delcasso, Sachira Denagamage, Zelie Britton, Ann M Graybiel
Understanding the neural mechanisms underlying human cognition and determining the causal factors for the development of brain pathologies are among the greatest challenges for society. Electrophysiological recordings offer remarkable observations of brain activity as they provide highly precise representations of information coding in both temporal and spatial domains. With the development of genetic tools over the last decades, mice have been a key model organism in neuroscience. However, conducting chronic in vivo electrophysiology in awake, behaving mice remains technically challenging, and this difficulty prevents many research teams from acquiring critical recordings in their mouse models...
2018: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/29868620/herd-level-mastitis-associated-costs-on-canadian-dairy-farms
#5
Mahjoob Aghamohammadi, Denis Haine, David F Kelton, Herman W Barkema, Henk Hogeveen, Gregory P Keefe, Simon Dufour
Mastitis imposes considerable and recurring economic losses on the dairy industry worldwide. The main objective of this study was to estimate herd-level costs incurred by expenditures and production losses associated with mastitis on Canadian dairy farms in 2015, based on producer reports. Previously, published mastitis economic frameworks were used to develop an economic model with the most important cost components. Components investigated were divided between clinical mastitis (CM), subclinical mastitis (SCM), and other costs components (i...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29864776/sudden-cardiac-and-noncardiac-death-in-sports-epidemiology-causes-pathogenesis-and-prevention
#6
Giuseppe Lippi, Emmanuel J Favaloro, Fabian Sanchis-Gomar
Although few doubts remain that physical exercise should be widely promoted for maintenance of health and fitness, the risk of adverse events such as sudden death (especially due to cardiac causes, i.e., sudden cardiac death [SCD]) during exercise remains tangible. The overall risk of sudden death in athletes is relatively low (i.e., usually comprised between 0.1 and 38/100,000 person-years), and globally comparable to that of the general population. However, up to 20% of all sudden death cases are still recorded while exercising...
June 4, 2018: Seminars in Thrombosis and Hemostasis
https://www.readbyqxmd.com/read/29861211/the-effect-of-rheumatoid-arthritis-on-the-risk-of-cerebrovascular-disease-and-coronary-artery-disease-in-young-adults
#7
Yih-Ru Chen, Fang-I Hsieh, Chi-Ching Chang, Nai-Fang Chi, Hsin-Chiao Wu, Hung-Yi Chiou
BACKGROUND: Only a few studies have investigated the affect of rheumatoid arthritis (RA) on the risk of cerebrovascular disease (CVD)/coronary artery disease (CAD) in young adults. This study, therefore, examined the association between RA and the risk of CVD/CAD in young adults and the interaction effects between cardiovascular risk factors and RA on the risk of CVD/CAD. METHODS: Data regarding 52,840 subjects (10,568 patients with RA and 42,272 age-, sex-, urbanization-, and income-matched non-RA controls) were collected from the National Health Insurance Research Database (NHIRD) in 2006...
May 31, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29843607/a-potential-protective-element-of-myocardial-bridge-against-severe-obstructive-atherosclerosis-in-the-whole-coronary-system
#8
Lisheng Jiang, Min Zhang, Hong Zhang, Lan Shen, Qin Shao, Linghong Shen, Ben He
BACKGROUND: Myocardial bridge (MB) is generally described as a congenital benign variation. Previous studies have suggested that MB prevents atherosclerotic plaques from accumulating within the bridge segment but promotes coronary stenosis in the proximal segment adjacent to MB. However, it is still not clear whether MB has positive or negative effects on severe obstructive atherosclerosis in the whole coronary artery system. METHODS: In this study, 6774 patients with symptoms of angina who were clinically diagnosed coronary artery disease (CAD) or suspected CAD underwent coronary angiography (CAG) in our center...
May 29, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29801689/mendelian-randomization-its-impact-on-cardiovascular-disease
#9
REVIEW
Masa-Aki Kawashiri, Hayato Tada, Akihiro Nomura, Masakazu Yamagishi
Cardiovascular diseases and their risk factors are inheritable. Single nucleotide polymorphisms in the human genome are found in around 1 in 1000 base pairs, and this may affect the genetic variety of individuals. During meiosis, any genetic information is randomized and is independent of other characteristics. In a Mendelian randomization study (MRS), a genetic variant associated with biomarker is used as a proxy for the biomarker, and the outcomes are compared between the groups harboring the effect alleles and a group with the reference allele...
May 22, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29796309/deubiquitinase-function-of-a20-maintains-and-repairs-endothelial-barrier-after-lung-vascular-injury
#10
Dheeraj Soni, Dong-Mei Wang, Sushil C Regmi, Manish Mittal, Stephen M Vogel, Dirk Schlüter, Chinnaswamy Tiruppathi
Vascular endothelial cadherin (VE-cad) expression at endothelial adherens junctions (AJs) regulates vascular homeostasis. Here we show that endothelial A20 is required for VE-cad expression at AJs to maintain and repair the injured endothelial barrier. In endothelial cell (EC)-restricted Tnfaip3 (A20) knockout ( A20 ∆EC ) mice, LPS challenge caused uncontrolled lung vascular leak and persistent sequestration of polymorphonuclear neutrophil (PMNs). Importantly, A20 ∆EC mice exhibited drastically reduced VE-cad expression in lungs compared with wild-type counterparts...
2018: Cell Death Discovery
https://www.readbyqxmd.com/read/29790033/biomechanical-properties-of-polymer-infiltrated-ceramic-crowns-on-one-piece-zirconia-implants-after-long-term-chewing-simulation
#11
Pia Baumgart, Holger Kirsten, Rainer Haak, Constanze Olms
BACKGROUND: Implant and superstructure provide a complex system, which has to withstand oral conditions. Concerning the brittleness of many ceramics, fractures are a greatly feared issue. Therefore, polymer-infiltrated ceramic networks (PICNs) were developed. Because of its low Young's modulus and high elastic modulus, the PICN crown on a one-piece zirconia implant might absorb forces to prevent the system from fracturing in order to sustain oral forces. Recommendations for the material of superstructure on zirconia implants are lacking, and only one study investigates PICN crowns on these types of implants...
May 23, 2018: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/29788285/altered-asparagine-and-glutamate-homeostasis-precede-coronary-artery-disease-and-type-2-diabetes
#12
Filip Ottosson, Einar Smith, Olle Melander, Céline Fernandez
Context: Type 2 diabetes (T2DM) is accompanied by an increased risk of coronary artery disease (CAD), but the overlapping metabolic disturbances preceding both diseases are insufficiently described. Objective: We hypothesized that alterations in metabolism occur years before clinical manifestation of T2DM and CAD and that these alterations are reflected in the plasma metabolome. We thus aimed to identify plasma metabolites that predict future T2DM and CAD. Design: Using targeted liquid chromatography-mass spectrometry (LC-MS), 35 plasma metabolites (amino acid metabolites and acylcarnitines) were quantified in 1049 individuals, free from CAD and diabetes, drawn from a population sample of 5386 in the Malmö Preventive Project (mean age 69...
May 16, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29785339/identification-of-potential-crucial-genes-and-pathways-associated-with-vein-graft-restenosis-based-on-gene-expression-analysis-in-experimental-rabbits
#13
Qiang Liu, Xiujie Yin, Mingzhu Li, Li Wan, Liqiao Liu, Xiang Zhong, Zhuoqi Liu, Qun Wang
Occlusive artery disease (CAD) is the leading cause of death worldwide. Bypass graft surgery remains the most prevalently performed treatment for occlusive arterial disease, and veins are the most frequently used conduits for surgical revascularization. However, the clinical efficacy of bypass graft surgery is highly affected by the long-term potency rates of vein grafts, and no optimal treatments are available for the prevention of vein graft restenosis (VGR) at present. Hence, there is an urgent need to improve our understanding of the molecular mechanisms involved in mediating VGR...
2018: PeerJ
https://www.readbyqxmd.com/read/29778671/international-study-of-comparative-health-effectiveness-with-medical-and-invasive-approaches-ischemia-trial-rationale-and-design
#14
David J Maron, Judith S Hochman, Sean M O'Brien, Harmony R Reynolds, William E Boden, Gregg W Stone, Sripal Bangalore, John A Spertus, Daniel B Mark, Karen P Alexander, Leslee Shaw, Jeffrey S Berger, T Bruce Ferguson, David O Williams, Robert A Harrington, Yves Rosenberg
BACKGROUND: Prior trials comparing a strategy of optimal medical therapy with or without revascularization have not shown that revascularization reduces cardiovascular events in patients with stable ischemic heart disease (SIHD). However, those trials only included participants in whom coronary anatomy was known prior to randomization and did not include sufficient numbers of participants with significant ischemia. It remains unknown whether a routine invasive approach offers incremental value over a conservative approach with catheterization reserved for failure of medical therapy in patients with moderate or severe ischemia...
April 21, 2018: American Heart Journal
https://www.readbyqxmd.com/read/29754662/rationale-and-design-of-a-trial-to-personalize-risk-assessment-in-familial-coronary-artery-disease
#15
Thomas H Marwick, Kristyn Whitmore, Stephen J Nicholls, Tony Stanton, Geoffrey Mitchell, Andrew Tonkin, Christopher Blizzard, Amanda Neil, Catherine Jones, Gerald F Watts
BACKGROUND: The lifetime risk of coronary artery disease (CAD) is doubled in people with a family history of premature disease, yet this risk is not captured in most 5- or 10-year risk assessment algorithms. Coronary artery calcium scoring (CCS) is a marker of subclinical CAD risk, which has been shown in observational studies to provide prognostic information that is incremental to clinical assessment; is relatively inexpensive; and is performed with a small radiation dose. However, the use of CCS in guiding prevention is not strongly supported by guidelines...
May 2018: American Heart Journal
https://www.readbyqxmd.com/read/29752179/the-effect-of-eicosapentaenoic-and-docosahexaenoic-acids-on-physical-function-exercise-and-joint-replacement-in-patients-with-coronary-artery-disease-a-secondary-analysis-of-a-randomized-clinical-trial
#16
Abdulhamied Alfaddagh, Tarec K Elajami, Mohamad Saleh, Mohamad Elajami, Bruce R Bistrian, Francine K Welty
BACKGROUND: Poor physical function impairs fitness and exercise and is associated with worse cardiovascular outcomes and all-cause mortality. Joint pain and stiffness limit physical function. OBJECTIVE: To determine if eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation improves physical function and exercise in coronary artery disease (CAD) patients. METHODS: A total of 291 subjects with stable CAD were randomized to either Lovaza (1...
March 14, 2018: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29749982/prevalence-of-multiple-coronary-artery-disease-risk-factors-in-kerman-a-population-based-study-in-southeast-iran
#17
Hamid Najafipour, Mahdi Afshari, Farzaneh Rostamzadeh
Background: The risk of disease with 1 risk factor is increased by the presence of additional risk factors. The goal of this study was to assess the prevalence of multiple coronary artery disease (CAD) risk factors among adults in Kerman, Iran, to identify the population groups most at risk. Methods: The present study included 5900 adults aged between 15 and 75 years in 2011 in Kerman, Iran. They were selected by 1-stage cluster sampling. Blood pressure, fasting blood glucose, lipids, and 6 CAD risk factors were assessed in the study population...
March 2018: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29747917/elective-coronary-revascularization-procedures-in-patients-with-stable-coronary-artery-disease-incidence-determinants-and-outcome-from-the-coronor-study
#18
Martial Hamon, Gilles Lemesle, Thibaud Meurice, Olivier Tricot, Nicolas Lamblin, Christophe Bauters
OBJECTIVES: The authors sought to describe the incidence, determinants, and outcome of elective coronary revascularization (ECR) in patients with stable coronary artery disease (CAD). BACKGROUND: Observational data are lacking regarding the practice of ECR in patients with stable CAD receiving modern secondary prevention. METHODS: The authors analyzed coronary revascularization procedures performed during a 5-year follow-up in 4,094 stable CAD outpatients included in the prospective multicenter CORONOR (Suivi d'une cohorte de patients COROnariens stables en région NORd-Pas-de-Calais) registry...
May 14, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29745255/pannexin-1-channels-on-endothelial-cells-mediate-vascular-inflammation-during-lung-ischemia-reperfusion-injury
#19
Ashish K Sharma, Eric J Charles, Yunge Zhao, Adishesh K Narahari, Pranav K Baderdinni, Miranda E Good, Ulrike M Lorenz, Irving L Kron, Douglas A Bayliss, Kodi S Ravichandran, Brant E Isakson, Victor E Laubach
Ischemia-reperfusion injury (IRI), which involves inflammation, vascular permeability, and edema, remains a major challenge after lung transplantation. Pannexin 1 (Panx1) channels modulate cellular ATP release during inflammation. This study tests the hypothesis that endothelial Panx1 is a key mediator of vascular inflammation and edema after IR and that IRI can be blocked by Panx1 antagonism. A murine hilar ligation model of IRI was utilized whereby left lungs underwent 1 hour of ischemia and 2 hours of reperfusion...
May 10, 2018: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/29724553/effect-of-metal-opaquer-on-the-final-color-of-3-ceramic-crown-types-on-3-abutment-configurations
#20
Rabia Arif, Burak Yilmaz, Aras Mortazavi, Tuncer B Ozcelik, William M Johnston
STATEMENT OF PROBLEM: The effect of a recently introduced metal opaquer when used to mask the color of a titanium abutment under ceramic crown systems is unknown. PURPOSE: The purpose of this study was to compare the color coordinates of 3 ceramic crown types-characterized monolithic lithium disilicate (LDC) (IPS e.max; Ivoclar Vivadent AG), layered lithium disilicate (LDL) (IPS e.max; Ivoclar Vivadent AG), and layered zirconia (ZL) (H.C. Starck)-on 3 abutment configurations, nonopaqued titanium (Ti), resin opaqued titanium (Op), and zirconia (Zir)...
April 30, 2018: Journal of Prosthetic Dentistry
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