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https://www.readbyqxmd.com/read/29353461/eye-blinks-are-related-to-auditory-information-processing-evidence-from-a-complex-speech-perception-task
#1
S Oliver Kobald, Edmund Wascher, Holger Heppner, Stephan Getzmann
There is increasing evidence that spontaneous eye blinks are related to mental states and can predict performance in certain tasks because of their relation to dopaminergic activity. Moreover, it has been shown that eye blinks while performing visual tasks are preferably executed not before all available information and even the manual response has been processed and given. Thus, blinks provide a natural endpoint of visual information processing. In the present study, we investigate to what degree such functional assignment of eye blinks also applies when only auditory stimuli are processed...
January 20, 2018: Psychological Research
https://www.readbyqxmd.com/read/29353452/random-regression-analysis-for-body-weights-and-main-morphological-traits-in-genetically-improved-farmed-tilapia-oreochromis-niloticus
#2
Jie He, Yunfeng Zhao, Jingli Zhao, Jin Gao, Pao Xu, Runqing Yang
To genetically analyse growth traits in genetically improved farmed tilapia (GIFT), the body weight (BWE) and main morphological traits, including body length (BL), body depth (BD), body width (BWI), head length (HL) and length of the caudal peduncle (CPL), were measured six times in growth duration on 1451 fish from 45 mixed families of full and half sibs. A random regression model (RRM) was used to model genetic changes of the growth traits with days of age and estimate the heritability for any growth point and genetic correlations between pairwise growth points...
January 20, 2018: Journal of Applied Genetics
https://www.readbyqxmd.com/read/29353440/healthy-lifestyle-promotion-in-primary-schools-through-the-board-game-kaledo-a-pilot-cluster-randomized-trial
#3
Emanuela Viggiano, Alessandro Viggiano, Anna Di Costanzo, Adela Viggiano, Andrea Viggiano, Eleonora Andreozzi, Vincenzo Romano, Claudia Vicidomini, Daniela Di Tuoro, Giuliana Gargano, Lucia Incarnato, Celeste Fevola, Pietro Volta, Caterina Tolomeo, Giuseppina Scianni, Caterina Santangelo, Maria Apicella, Roberta Battista, Maddalena Raia, Ilaria Valentino, Marianna Palumbo, Giovanni Messina, Antonietta Messina, Marcellino Monda, Bruno De Luca, Salvatore Amaro
The board game Kaledo was proven to be effective in improving nutrition knowledge and in modifying dietary behavior in students attending middle and high school. The present pilot study aims to reproduce these results in younger students (7-11 years old) attending primary school. A total of 1313 children from ten schools were recruited to participate in the present study. Participants were randomized into two groups: (1) the treatment group which consisted of playing Kaledo over 20 sessions and (2) the no intervention group...
January 20, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29353421/1-day-or-5-day-fecal-samples-which-one-is-more-beneficial-to-be-used-for-dna-based-gut-microbiota-study
#4
Tingting Su, Rongbei Liu, Yanqin Long, Sheng Quan, Sanchuan Lai, Lan Wang, Jianmin Si, Shujie Chen
Fecal sample collection is an important influential factor for DNA-based gut microbiota study. It is controversial whether the microbiome detected in fecal sample collected at one random day could fully represent the gut microbial community. The aim of the study is to figure out whether the use of fecal sample mixture collected at consecutive 5 days could more accurately represent gut microbial community. 1- and 5-day fecal samples were collected from 8 healthy adults and analyzed by 16S rRNA sequence. Our results indicated that both 1-day fecal samples and 5-day samples exhibited relatively high repeatability...
January 20, 2018: Current Microbiology
https://www.readbyqxmd.com/read/29353414/oral-administration-of-compound-probiotics-ameliorates-hfd-induced-gut-microbe-dysbiosis-and-chronic-metabolic-inflammation-via-the-g-protein-coupled-receptor-43-in-non-alcoholic-fatty-liver-disease-rats
#5
Yinji Liang, Shu Liang, Yupei Zhang, Yuanjun Deng, Yifang He, Yanning Chen, Chan Liu, Chenli Lin, Qinhe Yang
The aim of this study was to investigate how the effects of compound probiotics modulate the gut microbiota, short-chain fatty acid (SCFA), body composition, serum and liver lipids, and inflammatory markers in non-alcoholic fatty liver disease (NAFLD) rats. Twenty-four male SD rats were randomly divided into 3 groups: normal control group (standard feed), high-fat diet (HFD) feeding group (83% standard feed + 10% lard oil + 1.5% cholesterol + 0.5% cholate + 5% sucrose), and compound probiotics intervention group (HFD + 0...
January 20, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29353400/a-stard-compliant-prediction-model-for-diagnosing-thrombotic-microangiopathies
#6
Pietro Manuel Ferraro, Gianmarco Lombardi, Alessandro Naticchia, Antonio Sturniolo, Cecilia Zuppi, Valerio De Stefano, Patrizia Bonelli, Ruggero Buonocore, Gianfranco Cervellin, Giuseppe Lippi, Giovanni Gambaro
Aim of the study was the definition of a predictive model for the initial diagnosis of thrombotic microangiopathies (TMA). We retrospectively collected data on all adult patients admitted to the Gemelli Hospital from 2010 to 2014. ICD-9 codes from primary diagnoses were used for TMA diagnosis. Demographic and laboratory characteristics on admission of patients with TMA were then compared with a random sample of 500 patients with other diagnoses. The prediction model was externally validated in a cohort from another hospital...
January 20, 2018: Journal of Nephrology
https://www.readbyqxmd.com/read/29353388/outcomes-and-cost-effectiveness-of-ultrasound-guided-injection-of-the-trochanteric-bursa
#7
William G Mitchell, Sharon C Kettwich, Wilmer L Sibbitt, Randy R Sibbitt, Maheswari Muruganandam, Noelle A Rolle, William A Hayward, Roderick A Fields, Luis P Roldan, N Suzanne Emil, Monthida Fangtham, Arthur D Bankhurst
We hypothesized that ultrasound (US) guidance improves outcomes of corticosteroid injection of trochanteric bursitis. 40 patients with greater trochanteric pain syndrome defined by pain to palpation over the trochanteric bursa were randomized to injection with 5 ml of 1% lidocaine and 80 mg of methylprednisolone using (1) conventional anatomic landmark palpation guidance or (2) US guidance. Procedural pain (Visual Analogue Pain Scale), pain at outcome (2 weeks and 6 months), therapeutic duration, time-to-next intervention, and costs were determined...
January 20, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29353384/the-effect-of-self-care-education-on-emotional-intelligence-of-iranian-nursing-students-a-quasi-experimental-study
#8
Amir Hossein Goudarzian, Masoumeh Bagheri Nesami, Parisa Sedghi, Mahsan Gholami, Maryam Faraji, Mahdi Babaei Hatkehlouei
This study aimed to determine the effect of self-care training on emotional intelligence of nursing students. This quasi-experimental study was conducted on nursing students of Mazandaran University of Medical Sciences in 2016. The subjects (60 students) that were collected with random sampling method were divided into experimental and control groups, and then, self-care behaviors were taught to the experimental group' students in 12 sessions by using a checklist. The subjects of control group were not taught...
January 20, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29353367/surveillance-for-cancer-recurrence-in-long-term-young-breast-cancer-survivors-randomly-selected-from-a-statewide-cancer-registry
#9
Tarsha Jones, Debra Duquette, Meghan Underhill, Chang Ming, Kari E Mendelsohn-Victor, Beth Anderson, Kara J Milliron, Glenn Copeland, Nancy K Janz, Laurel L Northouse, Sonia M Duffy, Sofia D Merajver, Maria C Katapodi
PURPOSE: This study examined clinical breast exam (CBE) and mammography surveillance in long-term young breast cancer survivors (YBCS) and identified barriers and facilitators to cancer surveillance practices. METHODS: Data collected with a self-administered survey from a statewide, randomly selected sample of YBCS diagnosed with invasive breast cancer or ductal carcinoma in situ younger than 45 years old, stratified by race (Black vs. White/Other). Multivariate logistic regression models identified predictors of annual CBEs and mammograms...
January 20, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29353361/liming-induces-carbon-dioxide-co2-emission-in-psb-inoculated-alkaline-soil-supplemented-with-different-phosphorus-sources
#10
Muhammad Adnan, Zahir Shah, Muhammad Sharif, Hidayatur Rahman
Agricultural land is a major sink of global organic carbon (C). Its suitable management is crucial for improving C sequestration and reducing soil CO2 emission. Incubation experiments were performed to assess the impact of phosphate solubilizing bacterial (PSB) inoculation (inoculated and uninoculated) and soil calcification (4.78, 10, 15, and 20% crushed CaCO3) with phosphorus (P) sources [single superphosphate (SSP), rock phosphate (RP), farm yard manure (FYM), and poultry manure (PM)] in experiment 1 and with various rates of PM (4, 8, and 12 kg ha-1) in experiment 2 on cumulative soil respiration...
January 20, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29353339/chronic-pain-discomfort-quality-of-life-and-impact-on-sex-life-after-open-inguinal-hernia-mesh-repair-an-expertise-based-randomized-clinical-trial-comparing-lightweight-and-heavyweight-mesh
#11
M Rutegård, R Gümüsçü, G Stylianidis, P Nordin, E Nilsson, M M Haapamäki
PURPOSE: There is a paucity of high-quality evidence concerning mesh choice in open inguinal hernia repair. Using an expertise-based randomized clinical trial design, we aimed to evaluate the postoperative impact of two different mesh types on pain and discomfort, quality of life and sex life. METHODS: In two regional hospitals, male patients with primary inguinal hernia were randomized to one of two groups of surgeons that performed the Lichtenstein operation. One group of surgeons used a heavyweight polypropylene mesh (90 g/m2, Bard™ Flatmesh, Davol) while the second group employed a lightweight mesh (28 g/m2, ULTRAPRO™, Ethicon)...
January 20, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29353277/a-critical-review-of-the-consensus-statement-from-the-european-atherosclerosis-society-consensus-panel-2017
#12
Harumi Okuyama, Tomohito Hamazaki, Rokuro Hama, Yoichi Ogushi, Tetsuyuki Kobayashi, Naoki Ohara, Hajime Uchino
BACKGROUND: The Consensus Statement from the European Atherosclerosis Society (EAS) Consensus Panel 2017 concludes on the basis of 3 different types of clinical studies that low-density lipoprotein (LDL) causes atherosclerotic cardiovascular disease (ASCVD). In Mendelian randomization studies, rare genetic mutations affecting LDL receptor function were found to cause higher or lower LDL-C levels, which are associated with correspondingly altered ASCVD risk. In prospective cohort studies and randomized controlled trials (RCTs) of statins, a remarkably consistent log-linear association was demonstrated between the absolute magnitude of LDL-C exposure and ASCVD risk...
January 19, 2018: Pharmacology
https://www.readbyqxmd.com/read/29353274/postoperative-immobilization-following-occipitocervical-fusion-in-the-pediatric-population-outcome-evaluation-and-review-of-literature
#13
Alexandre R Pingarilho, Paulo M Porto de Melo, Samer K Elbabaa
The scientific literature does not have a consensus about the role and method of postoperative immobilization after occipitocervical fusion in the pediatric population. The primary goal of this study is to review the medical literature and evaluate different immobilization methods and their impact on fusion, following the surgical management of craniocervical instability in children. It started with an extensive research of randomized controlled trials, series of cases and case reports, describing occipitocervical junction pathologies, clinical, epidemiological characteristics, and treatment...
January 20, 2018: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29353233/cardiovascular-safety-long-term-noncardiovascular-safety-and-efficacy-of-sodium-glucose-cotransporter-2-inhibitors-in-patients-with-type-2-diabetes-mellitus-a-systemic-review-and-meta-analysis-with-trial-sequential-analysis
#14
REVIEW
Xin-Lin Zhang, Qing-Qing Zhu, Yu-Han Chen, Xue-Ling Li, Fu Chen, Jian-An Huang, Biao Xu
BACKGROUND: The cardiovascular and long-term noncardiovascular safety and efficacy of SGLT2 (sodium-glucose cotransporter 2) inhibitors have not been well documented. METHODS AND RESULTS: For cardiovascular outcomes, we performed a meta-analysis with trial sequential analysis of randomized controlled trials and adjusted observational studies, each with a minimum of 26 weeks and 2000 patient-years of follow-up. For long-term noncardiovascular safety and efficacy outcome analyses, we included only randomized controlled trials with at least 2 years and 1000 patient-years of follow-up...
January 20, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29353148/light-and-electron-microscopic-observations-on-the-organization-of-skin-and-associated-glands-of-two-caecilian-amphibians-from-western-ghats-of-india
#15
Arun Damodaran, Beyo Reston Saroja, Ramachandran Kotharambath, Akbarsha Mohammad Abdulkader, Oommen V Oommen, Divya Lekha
We adopted light and electron microscopy to understand the structure of the skin of two species of caecilians, Ichthyophis tricolor and Uraeotyphlus cf. oxyurus, from Western Ghats of Kerala, India. The surface of the skin of these caecilians contains an irregular pattern of microridges. Oval, round and polymorphic glandular openings are randomly distributed all over the skin surface. Most of the openings are funnel shaped. The epithelial cells along the rim of the opening descend into the tunnel of the duct...
January 9, 2018: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/29353098/the-anti-inflammatory-effects-of-statins-on-patients-with-rheumatoid-arthritis-a-systemic-review-and-meta-analysis-of-15-randomized-controlled-trials
#16
REVIEW
Guo-Min Li, Jie Zhao, Bing Li, Xiao-Fei Zhang, Jian-Xiong Ma, Xin-Long Ma, Jun Liu
BACKGROUND: Over the past several years, numerous studies investigated the anti-inflammatory effects of statin on patients with RA. However, the findings of the individual studies were often inconsistent or conflicting. MATERIALS AND METHODS: The Pubmed, Web of Science, Embase, Cochrane Library and CNKI literature databases were searched in order to identify randomized controlled clinical trials where the association between the anti-inflammatory effect of statin and RA was investigated...
January 15, 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29353026/efficacy-and-safety-of-lebrikizumab-an-anti-il-13-monoclonal-antibody-in-adults-with-moderate-to-severe-atopic-dermatitis-inadequately-controlled-by-topical-corticosteroids-a-randomized-placebo-controlled-phase-ii-trial-treble
#17
Eric L Simpson, Carsten Flohr, Lawrence F Eichenfield, Thomas Bieber, Howard Sofen, Alain Taïeb, Ryan Owen, Wendy Putnam, Marcela Castro, Kendra DeBusk, Chin-Yu Lin, Athina Voulgari, Karl Yen, Theodore A Omachi
BACKGROUND: Interleukin (IL)-13 plays a key role in type 2 inflammation and is an emerging pathogenic mediator in atopic dermatitis. OBJECTIVE: We investigated the efficacy and safety of lebrikizumab, an anti-IL-13 monoclonal antibody, as add-on to topical corticosteroid (TCS). METHODS: A randomized, placebo-controlled, double-blind, phase II study. Adults with moderate-to-severe AD were required to use twice-daily TCS, and randomized (1:1:1:1) to lebrikizumab 125 mg single dose (SD), 250 mg SD, 125 mg once every 4 weeks (Q4W), or placebo Q4W for 12 weeks, after 2-week TCS run-in...
January 15, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29353025/efficacy-and-safety-of-fezakinumab-an-anti-il-22-monoclonal-antibody-in-adults-with-moderate-to-severe-atopic-dermatitis-inadequately-controlled-by-conventional-treatments-a-randomized-double-blind-phase-2a-trial
#18
Emma Guttman-Yassky, Patrick M Brunner, Avidan U Neumann, Saakshi Khattri, Ana B Pavel, Kunal Malik, Giselle K Singer, Danielle Baum, Patricia Gilleaudeau, Mary Sullivan-Whalen, Sharon Rose, Shelbi Jim On, Xuan Li, Judilyn Fuentes-Duculan, Yeriel Estrada, Sandra Garcet, Claudia Traidl-Hoffmann, James G Krueger, Mark G Lebwohl
BACKGROUND: IL-22 promotes epidermal hyperplasia and inhibits skin barrier function. OBJECTIVE: Evaluate IL-22 blockade in adults with moderate-to-severe atopic dermatitis (AD). METHODS: Randomized, double-blind, placebo-controlled trial with intravenous fezakinumab monotherapy every 2wks for 10wks, with follow-up assessments until 20wks. SCORAD change from baseline at 12wks served as primary endpoint. RESULTS: At 12wks, mean SCORAD decline was 13·8±2·7 (fezakinumab) vs...
January 15, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29353006/comparing-the-portion-size-effect-in-women-with-and-without-extended-training-in-portion-control-a-follow-up-to-the-portion-control-strategies-trial
#19
Faris M Zuraikat, Liane S Roe, Christine E Sanchez, Barbara J Rolls
Following a 1-year randomized controlled trial that tested how weight loss was influenced by different targeted strategies for managing food portions, we evaluated whether the effect of portion size on intake in a controlled setting was attenuated in trained participants compared to untrained controls. Subjects were 3 groups of women: 39 participants with overweight and obesity from the Portion-Control Strategies Trial, 34 controls with overweight and obesity, and 29 controls with normal weight. In a crossover design, on 4 different occasions subjects were served a meal consisting of 7 foods that differed in energy density (ED)...
January 15, 2018: Appetite
https://www.readbyqxmd.com/read/29353004/leishmania-tropica-isolates-from-non-healed-and-healed-patients-in-iran-a-molecular-typing-and-phylogenetic-analysis
#20
Mehdi Bamorovat, Iraj Sharifi, Mohammad Ali Mohammadi, Sana Eybpoosh, Saeid Nasibi, Mohammad Reza Aflatoonian, Ahmad Khosravi
The precise identification of the parasite species causing leishmaniasis is essential for selecting proper treatment modality. The present study aims to compare the nucleotide variations of the ITS1, 7SL RNA, and Hsp70 sequences between non-healed and healed anthroponotic cutaneous leishmaniasis (ACL) patients in major foci in Iran. A case-control study was carried out from September 2015 to October 2016 in the cities of Kerman and Bam, in the southeast of Iran. Randomly selected skin-scraping lesions of 40 patients (20 non-healed and 20 healed) were examined and the organisms were grown in a culture medium...
January 15, 2018: Microbial Pathogenesis
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