keyword
MENU ▼
Read by QxMD icon Read
search

bioprint OR bioprinter OR bioprinted OR bioprinting

keyword
https://www.readbyqxmd.com/read/28632140/thermal-stability-and-rheological-properties-of-the-non-stick-caf1-biomaterial
#1
Yakup Ulusu, Gema Dura, Helen Waller, Matthew Benning, David Fulton, Jeremy Lakey, Daniel Thomas Peters
The ability to culture cells in three dimensions has many applications, from drug discovery to wound healing. 3D cell culture methods often require appropriate scaffolds that mimic the cellular environments of different tissue types. The choice of material from which these scaffolds are made is of paramount importance, as its properties will define the manner in which cells interact with the scaffold. Caf1 is a protein polymer that is secreted from its host organism, Yersinia pestis, to enable escape from phagocytosis...
June 20, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28631624/printing-induced-cell-injury-evaluation-during-laser-printing-of-3t3-mouse-fibroblasts
#2
Zhengyi Zhang, Wenxuan Chai, Ruitong Xiong, Lei Zhou, Yong Huang
Three-dimensional bioprinting has emerged as a promising solution for the freeform fabrication of living cellular constructs, which can be used for tissue/organ transplantation and tissue models. During bioprinting, some living cells are unavoidably injured and may become necrotic or apoptotic cells. This study aims to investigate the printing-induced cell injury and evaluates injury types of post-printing cells using the annexin V/7-aminoactinomycin D and FAM-DEVD-FMK/propidium iodide assays during laser printing of NIH 3T3 mouse fibroblasts...
June 20, 2017: Biofabrication
https://www.readbyqxmd.com/read/28617667/a-heuristic-computational-model-of-basic-cellular-processes-and-oxygenation-during-spheroid-dependent-biofabrication
#3
T J Sego, U Kasacheuski, D Hauersperger, A Tovar, N I Moldovan
An emerging approach in biofabrication is the creation of 3D tissue constructs through scaffold-free, cell spheroid-only methods. The basic mechanism in this technology is spheroid fusion, which is driven by the minimization of energy, the same biophysical mechanism that governs spheroid formation. However, other factors such as oxygen and metabolite accessibility within spheroids impact on spheroid properties and their ability to form larger-scale structures. The goal of our work is to develop a simulation platform eventually capable of predicting the conditions that minimize metabolism-related cell loss within spheroids...
June 15, 2017: Biofabrication
https://www.readbyqxmd.com/read/28600873/bone-tissue-bioprinting-for-craniofacial-reconstruction
#4
REVIEW
Pallab Datta, Veli Ozbolat, Bugra Ayan, Aman Dhawan, Ibrahim T Ozbolat
Craniofacial (CF) tissue is an architecturally complex tissue consisting of both bone and soft tissues with significant patient specific variations. Conditions of congenital abnormalities, tumor resection surgeries, and traumatic injuries of the CF skeleton can result in major deficits of bone tissue. Despite advances in surgical reconstruction techniques, management of CF osseous deficits remains a challenge. Due its inherent versatility, bioprinting offers a promising solution to address these issues. In this review, we present and analyze the current state of bioprinting of bone tissue and highlight how these techniques may be adapted to serve regenerative therapies for CF applications...
June 10, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28597844/study-of-gelatin-as-an-effective-energy-absorbing-layer-for-laser-bioprinting
#5
Ruitong Xiong, Zhengyi Zhang, Wenxuan Chai, Douglas B Chrisey, Yong Huang
Laser-induced forward transfer printing, also commonly known as laser printing, has been widely implemented for three-dimensional bioprinting due to its unique orifice-free nature during printing. However, the printing quality has the potential to be further improved for various laser bioprinting applications. The objectives of this study are to investigate the feasibility of using gelatin as an energy absorbing layer (EAL) material for laser bioprinting and its effects on the quality of printed constructs, bioink printability, and post-printing cell viability and process-induced DNA damage...
June 9, 2017: Biofabrication
https://www.readbyqxmd.com/read/28594678/transplantation-of-bioprinted-tissues-and-organs-technical-and-clinical-challenges-and-future-perspectives
#6
Dino J Ravnic, Ashley N Leberfinger, Srinivas V Koduru, Monika Hospodiuk, Kazim K Moncal, Pallab Datta, Madhuri Dey, Elias Rizk, Ibrahim T Ozbolat
: Three-dimensional (3D) bioprinting is a revolutionary technology in building living tissues and organs with precise anatomic control and cellular composition. Despite the great progress in bioprinting research, there has yet to be any clinical translation due to current limitations in building human-scale constructs, which are vascularized and readily implantable. In this article, we review the current limitations and challenges in 3D bioprinting, including in situ techniques, which are one of several clinical translational models to facilitate the application of this technology from bench to bedside...
July 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28592214/multinozzle-multichannel-temperature-deposition-system-for-construction-of-a-blood-vessel
#7
Huanbao Liu, Huixing Zhou, Haiming Lan, Fu Liu, Xuhan Wang
3D bioprinting is an emerging technology that drives us to construct the complicated tissues and organs consisting of various materials and cells, which has been in widespread use in tissue engineering and organ regeneration. However, the protection and accurate distribution of cells are the most urgent problems to achieve tissue and organ reconstruction. In this article, a multinozzle multichannel temperature deposition and manufacturing (MTDM) system is proposed to fabricate a blood vessel with heterogeneous materials and gradient hierarchical porous structures, which enables not only the reconstruction of a blood vessel with an accurate 3D model structure but also the capacity to distribute bioactive materials such as growth factors, nutrient substance, and so on...
June 1, 2017: SLAS Technology
https://www.readbyqxmd.com/read/28589446/bioprinting-and-organ-on-chip-applications-towards-personalized-medicine-for-bone-diseases
#8
Chiara Arrigoni, Mara Gilardi, Simone Bersini, Christian Candrian, Matteo Moretti
The skeleton supports and confers structure to the whole body but several pathological and traumatic conditions affect the bone tissue. Most of those pathological conditions are specific and different among different patients, such as bone defects due to traumatic injuries or bone remodeling alterations due to congenital diseases. In this context, the development of personalized therapies would be highly desirable. In recent years the advent of innovative techniques like bioprinting and microfluidic organ-on-chip raised hopes of achieving key tools helping the application of personalized therapies for bone diseases...
June 6, 2017: Stem Cell Reviews
https://www.readbyqxmd.com/read/28586346/3d-bioprinting-of-methacrylated-hyaluronic-acid-meha-hydrogel-with-intrinsic-osteogenicity
#9
Michelle T Poldervaart, Birgit Goversen, Mylene de Ruijter, Anna Abbadessa, Ferry P W Melchels, F Cumhur Öner, Wouter J A Dhert, Tina Vermonden, Jacqueline Alblas
In bone regenerative medicine there is a need for suitable bone substitutes. Hydrogels have excellent biocompatible and biodegradable characteristics, but their visco-elastic properties limit their applicability, especially with respect to 3D bioprinting. In this study, we modified the naturally occurring extracellular matrix glycosaminoglycan hyaluronic acid (HA), in order to yield photo-crosslinkable hydrogels with increased mechanical stiffness and long-term stability, and with minimal decrease in cytocompatibility...
2017: PloS One
https://www.readbyqxmd.com/read/28578251/cutting-edge-platforms-in-cardiac-tissue-engineering
#10
REVIEW
Sharon Fleischer, Ron Feiner, Tal Dvir
As cardiac disease takes a higher toll with each passing year, the need for new therapies to deal with the scarcity in heart donors becomes ever more pressing. Cardiac tissue engineering holds the promise of creating functional replacement tissues to repair heart tissue damage. In an attempt to bridge the gap between the lab and clinical realization, the field has made major strides. In this review, we will discuss state of the art technologies such as layer-by-layer assembly, bioprinting and bionic tissue engineering, all developed to overcome some of the major hurdles faced in the field...
June 1, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28575964/scaffolds-for-bone-tissue-engineering-state-of-the-art-and-new-perspectives
#11
REVIEW
Livia Roseti, Valentina Parisi, Mauro Petretta, Carola Cavallo, Giovanna Desando, Isabella Bartolotti, Brunella Grigolo
This review is intended to give a state of the art description of scaffold-based strategies utilized in Bone Tissue Engineering. Numerous scaffolds have been tested in the orthopedic field with the aim of improving cell viability, attachment, proliferation and homing, osteogenic differentiation, vascularization, host integration and load bearing. The main traits that characterize a scaffold suitable for bone regeneration concerning its biological requirements, structural features, composition, and types of fabrication are described in detail...
September 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28569243/cell-sheet-based-bionk-for-3d-bioprinting-applications
#12
Ezgi Bakirci, Burak Toprakhisar, Mehmet Zeybek, Gozde Ozaydin Ince, Bahattin Koc
In this research, a novel development of bioink from cell sheets is presented for scaffold free bioprinting applications. Poly(N-isopropylacrylamide) (PNIPAAm) coated surfaces were first prepared by using initiated Chemical Vapor Deposition (iCVD) method. Cell-sheets were then grown on these thermoresposnsive pNIPAAm coated surfaces and easily detached without disturbing delicate cell-extracellular matrix (ECM) and cell-cell interactions. The detached cells sheets were used to prepare cell sheet based bioink and bioprinted to form various shapes...
June 1, 2017: Biofabrication
https://www.readbyqxmd.com/read/28558161/-printability-of-candidate-biomaterials-for-extrusion-based-3d-printing-state-of-the-art
#13
REVIEW
Stuart Kyle, Zita M Jessop, Ayesha Al-Sabah, Iain S Whitaker
Regenerative medicine has been highlighted as one of the UK's 8 'Great Technologies' with the potential to revolutionize patient care in the 21st Century. Over the last decade, the concept of '3D bioprinting' has emerged, which allows the precise deposition of cell laden bioinks with the aim of engineering complex, functional tissues. For 3D printing to be used clinically, there is the need to produce advanced functional biomaterials, a new generation of bioinks with suitable cell culture and high shape/print fidelity, to match or exceed the physical, chemical and biological properties of human tissue...
May 30, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28552069/tissue-engineered-skin-and-wound-healing-current-strategies-and-future-directions
#14
Nandana Bhardwaj, Dimple Chouhan, Biman B Mandal
The global volume of skin damage or injuries has major healthcare implications and, accounts for about half of the world's annual expenditure in the healthcare sector. In the last two decades, tissue-engineered skin constructs have shown great promise in the treatment of various skin-related disorders such as deep burns and wounds. The treatment methods for skin replacement and repair have evolved from utilization of autologous epidermal sheets to more complex bilayered cutaneous tissue engineered skin substitutes...
May 25, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28550360/bioprinting-technologies-for-disease-modeling
#15
REVIEW
Adnan Memic, Ali Navaei, Bahram Mirani, Julio Alvin Vacacela Cordova, Musab Aldhahri, Alireza Dolatshahi-Pirouz, Mohsen Akbari, Mehdi Nikkhah
There is a great need for the development of biomimetic human tissue models that allow elucidation of the pathophysiological conditions involved in disease initiation and progression. Conventional two-dimensional (2D) in vitro assays and animal models have been unable to fully recapitulate the critical characteristics of human physiology. Alternatively, three-dimensional (3D) tissue models are often developed in a low-throughput manner and lack crucial native-like architecture. The recent emergence of bioprinting technologies has enabled creating 3D tissue models that address the critical challenges of conventional in vitro assays through the development of custom bioinks and patient derived cells coupled with well-defined arrangements of biomaterials...
May 26, 2017: Biotechnology Letters
https://www.readbyqxmd.com/read/28546955/biofabrication-and-biomaterials-for-urinary-tract-reconstruction
#16
REVIEW
Moustafa M Elsawy, Achala de Mel
Reconstructive urologists are constantly facing diverse and complex pathologies that require structural and functional restoration of urinary organs. There is always a demand for a biocompatible material to repair or substitute the urinary tract instead of using patient's autologous tissues with its associated morbidity. Biomimetic approaches are tissue-engineering tactics aiming to tailor the material physical and biological properties to behave physiologically similar to the urinary system. This review highlights the different strategies to mimic urinary tissues including modifications in structure, surface chemistry, and cellular response of a range of biological and synthetic materials...
2017: Research and Reports in Urology
https://www.readbyqxmd.com/read/28544655/3d-bioprinting-human-induced-pluripotent-stem-cell-constructs-for-in-situ-cell-proliferation-and-successive-multilineage-differentiation
#17
Qi Gu, Eva Tomaskovic-Crook, Gordon G Wallace, Jeremy M Crook
The ability to create 3D tissues from induced pluripotent stem cells (iPSCs) is poised to revolutionize stem cell research and regenerative medicine, including individualized, patient-specific stem cell-based treatments. There are, however, few examples of tissue engineering using iPSCs. Their culture and differentiation is predominantly planar for monolayer cell support or induction of self-organizing embryoids (EBs) and organoids. Bioprinting iPSCs with advanced biomaterials promises to augment efforts to develop 3D tissues, ideally comprising direct-write printing of cells for encapsulation, proliferation, and differentiation...
May 24, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28544472/engineering-muscle-cell-alignment-through-3d-bioprinting
#18
Pamela Mozetic, Sara Maria Giannitelli, Manuele Gori, Marcella Trombetta, Alberto Rainer
Processing of hydrogels represents a main challenge for the prospective application of additive manufacturing (AM) to soft tissue engineering. Furthermore, direct manufacturing of tissue precursors with a cell density similar to native tissues has the potential to overcome the extensive in vitro culture required for conventional cell-seeded scaffolds seeking to fabricate constructs with tailored structural and functional properties. In this work, we present a simple AM methodology that exploits the thermoresponsive behavior of a block copolymer (Pluronic(®) ) as a means to obtain good shape retention at physiological conditions and to induce cellular alignment...
May 22, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28540601/special-issue-organs-on-chips-3d-bioprinting-technologies-for-personalized-medicine
#19
EDITORIAL
Yaşar Murat Elçin
No abstract text is available yet for this article.
May 24, 2017: Stem Cell Reviews
https://www.readbyqxmd.com/read/28539292/-gelatin-alginate-hydrogel-scaffolds-prepared-by-3d-bioprinting-promotes-cell-adhesion-and-proliferation-of-human-dental-pulp-cells-in-vitro
#20
Hai-Yue Yu, Dan-Dan Ma, Bu-Ling Wu
OBJECTIVE: To evaluate the cytotoxicity of gelatin/alginate hydrogel scaffolds prepared by 3D bioprinting in human dental pulp cells (HDPCs) and compare the cell adhesion and proliferation of the cells seeded in the biomaterial using two different methods. METHODS: HDPCs isolated by tissue block culture and enzyme digestion were cultured and passaged. Gelatin/alginate hydrogel scaffolds were printed using a bioplotter, and the cytotoxicity of the aqueous extracts of the scaffold material was tested in the third passage of HDPCs using cell counting kit-8...
May 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
keyword
keyword
120201
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"