Li Zang, Yijun Li, Haojie Hao, Jiejie Liu, Yu Cheng, Bing Li, Yaqi Yin, Qian Zhang, Fei Gao, Haibin Wang, Shi Gu, Jia Li, Fengxiang Lin, Yingfei Zhu, Guanglei Tian, Yulong Chen, Weijun Gu, Jin Du, Kang Chen, Qinghua Guo, Guoqing Yang, Yu Pei, Wenhua Yan, Xianling Wang, Junhua Meng, Saichun Zhang, Jianming Ba, Zhaohui Lyu, Jingtao Dou, Weidong Han, Yiming Mu
BACKGROUND: To determine the efficacy and safety of umbilical cord-derived mesenchymal stem cells (UC-MSCs) in Chinese adults with type 2 diabetes mellitus (T2DM). METHODS: In this single-center, double-blinded, randomized, placebo-controlled phase II trial, 91 patients were randomly assigned to receive intravenous infusion of UC-MSCs (n = 45) or placebo (n = 46) three times with 4-week intervals and followed up for 48 weeks from October 2015 to December 2018...
May 3, 2022: Stem Cell Research & Therapy