Wen-Yan Tang, Jia-Hua Liu, Chun-Jin Peng, Yao Liao, Jie-Si Luo, Xi Sun, Yan-Lai Tang, Xue-Qun Luo
Systemic lupus erythematosus (SLE) is a rare, heterogeneous autoimmune and autoinflammatory disease that affects both sexes and all races, although this disease exhibits its highest incidence/prevalence among the black population and shows a predilection for women of reproductive age. Although SLE has no cure, treatment can help decrease its signs and symptoms. Thus, we should focus primarily on personalized treatment. Mesenchymal stem/stromal cells (MSCs), which are multipotent cells capable of differentiating into osteoblasts, chondrocytes, adipocytes, and myoblasts, among other cell types, are potential candidates for use in a promising strategy to treat severe and refractory SLE...
March 13, 2021: Archivum Immunologiae et Therapiae Experimentalis