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Arthiritis

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https://www.readbyqxmd.com/read/27875955/detection-the-mycoplasma-pneumonia-in-synovial-fluid-of-children-with-negative-culture-arthritis-a-cross-sectional-study-in-tehran-iran
#1
Samileh Noorbakhsh, Mohammad Reza Shokrollahi, Farideh Ebrahimi Taj, Vida Zarabi, Azardokht Tabatabaei
BACKGROUND: arthritis could be caused by different etiologies ranging from rheumatologic diseases to infectious conditions. Therefore, early diagnosis of etiology and treatment is important. The purpose of this study was to determine the the M.pneumonia in synovial fluid of children with arthritis by 2 methods (serology and qualitative PCR). Methods & materials: this trial was carried out as a cross sectional study in pediatric and orthopedic ward of Rasoul-e Akram hospital in Tehran, Iran...
November 21, 2016: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/27760092/anxiety-and-depression-levels-in-rheumatoid-arthritis-patients-before-and-after-joint-replacement-procedure
#2
Joanna Pietrzak, Paulina Kwarta, Michał Karbownik, Łukasz Mokros, Paula Zdanowicz, Dawid Miśkowiec, Andrzej Witusik, Adam Antczak, Tadeusz Pietras
: The progression of the inflammatory process in the course of rheumatoid arthiritis (RA) may cause a permanent destruction of joints, which in case of bigger ones (i.e. hip or knee) may be particularly a psychological burden for a patient. AIM: The aim of the study was to verify whether implantation of hip or knee endoprosthesis affect anxiety and depressive symptoms among patients with RA. MATERIALS AND METHODS: The study enrolled a group of 128 rheumatoid arthritis patients, including 64 patients before and 64 patients after the joint replacement procedure...
October 19, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/22393621/-functional-outcome-of-tuberculous-arthiritis-of-the-knee-in-a-male-moroccan-patient
#3
J Facione, A Stephan, L Thefene, I Loiret, J J Chapus, J Paysant, D Lagauche
PURPOSE: The purpose of this article is to present a case of tuberculous arthritis of the knee and discuss the importance of early diagnosis and rehabilitatin in management outcome. CASE REPORT: A 57-year-old Moroccan man with no medical history presented with a mass in the left knee associated with pain and fever. Analysis of aspirated fluid demonstrated sterile inflammatory liquid. Presumptive antibiotic therapy was ineffective. Diagnosis of tuberculous arthritis was made based on positive tuberculin skin test and interferon-release assays...
December 2011: Médecine Tropicale: Revue du Corps de Santé Colonial
https://www.readbyqxmd.com/read/21755088/gold-compounds-as-therapeutic-agents-for-human-diseases
#4
REVIEW
Susan J Berners-Price, Aleksandra Filipovska
The application of gold in medicine is traceable for several thousand years and Au(i) compounds have been used clinically to treat rheumatoid arthritis since the last century. Recently research into gold-based drugs for a range of human diseases has seen a renaissance. Old as well as new Au(i) and Au(iii) compounds have been used and designed with an aim of targeting cellular components that are implicated in the onset or progression of cancers, rheumatoid arthiritis, viral and parasitic diseases. In addition, new disease targets have been found for gold compounds that have given insight into the mechanism of action of these compounds, as well as in the molecular pathophysiology of human diseases...
September 2011: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/21383916/structural-insights-into-the-binding-of-mmp9-inhibitors
#5
Arpit Tandon, Siddharth Sinha
Matrix Metalloproteinase are family of enzymes responsible for degradation of extracellular matrix. MMP9 (gelatinase B) is one of the common matrix metalloproteinase that is associated with tissue destruction in a number of disease states such as rheumatoid arthiritis, fibrotic lung disease, dilated cardiomyopathy, as well as cancer invasion and metastasis. Recent study demonstrates that increased expression of MMP9 results in augmentation of myopathy with increased inflammation and fibernecrosis. Previous studies do not provide any conclusive information related to structural specificity of MMP9 inhibitors towards its active site, but with the availability of experimental structures it is now possible to study the structural specificity of MMP9 inhibitors...
2011: Bioinformation
https://www.readbyqxmd.com/read/21046924/autonomic-sympathetic-nervous-system-involvement-in-rheumatoid-arthiritis-patients
#6
Mukta P Bidikar, Rati B Ichaporia
Fifty Rheumatoid arthritis (RA) patients between the age group of 20 to 60 years were investigated for sympathetic autonomic functions using standard tests. All the patients liable to develop dysautonomia or having a treatment interfering with autonomic nervous system were excluded. Previous studies to evalute sympathetic nervous system involvement used only a single test like sweating response, orthostatic test. In the present study 3 tests of sympathetic nervous system evaluation have been used. The evaluation was done by cardiovascular tests like orthostatic test, sustained hand grip and cold pressor test...
January 2010: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/20954306/-renal-involvement-in-patients-with-rheumatoid-arthritis
#7
Kresimir Galesić, Ingrid Prkacin, Miroslav Tisljar, Jadranka Morović Vergles
In rheumatoid arthritis (RA) kidney is commonly affected organ with clinical presentation characterised by proteinuria (often nephrotic range) and microhematuria followed by chronic renal failure. This condition is well recognized as a rheumatoid nephropathy (rheumatoid glomerulonephritis), which is mediated by an immunological inflammation and by nephrotoxic effects of numerous drugs usually used in rheumatoid arthiritis treatment, such as NSAID, DMARD. In the patohistological examination various kinds of associated renal lesions could be seen...
2009: Reumatizam
https://www.readbyqxmd.com/read/18989744/multiple-abscesses-caused-by-salmonella-enterica-and-corynebacterium-pseudotuberculosis-in-a-dromedary-camel
#8
María T Tejedor-Junco, Pablo Lupiola, María J Caballero, Juan A Corbera, Carlos Gutierrez
A rare case of arthritis, peri-arthiritis and pleurits associated with Salmonella enterica and Corynebacterium pseudotuberculosis infection in a dromedary camel is reported. Articular infections caused by Non-typhoidal Salmonella have been exceptionally described in human medicine. To our knowledge, this would be the first description of articular infections associated with Non-thyphoidal Salmonella in other mammals than humans. Possible pathogenesis of the infection is discussed.
June 2009: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/18600328/mucosal-administration-of-an-altered-cii263-272-peptide-inhibits-collagen-induced-arthritis-by-suppression-of-th1-th17-cells-and-expansion-of-regulatory-t-cells
#9
Jinxia Zhao, Ru Li, Jing He, Jinxia Shi, Li Long, Zhanguo Li
Rheumatoid arthritis (RA) is a systemic autoimmune disease mediated by T cells. Collagen type II (CII) is one of the autoantigens associated with RA. CII263-272 is a predominant CII antigenic peptide that can induce T-cell activation upon binding to MHC and interaction with the appropriate T-cell receptor (TCR). Altered CII263-272 peptides with substitution of specific amino acids could bind to RA-associated HLA-DR4/1 with no T cell stimulating effects and could inhibit T cell activation in RA. We performed this study to evaluate the effect of mucosal administration and to explore the mechanism of the inhibitory effect of altered CII263-272 peptide (267Q-->A, 270K-->A and 271G-->A) on collagen induced arthritis (CIA)...
November 2008: Rheumatology International
https://www.readbyqxmd.com/read/17144587/-a-case-of-rheumatoid-lung-complicated-by-selapina-induced-pneumonia
#10
Seiko Nakayama, Hiroshi Mukae, Yuji Ishimatsu, Kanako Sugiyama, Mioko Ide, Hiroshi Ishimoto, Keiko Hisatomi, Hiroshi Ishii, Koh Abel, Yoshiyuki Ozono, Shigeru Kohno
SELAPINA is generic product of PL granule which is one of the most common forms of combination remedies for the common cold in Japan, and includes acetaminophen. We report a case of SELAPINA-induced pneumonia successfully treated with glucocorticoid pulse therapy followed by orally administered prednisolone. A 68-year-old woman, who had been treated for rheumatoid arthiritis with pulmonary involvement, took SELAPINA with an antibiotic for 6 days because of her cold symptoms. She then suffered a high fever, cough, dyspnea, vomiting and diarrhea...
November 2006: Nihon Kokyūki Gakkai Zasshi, the Journal of the Japanese Respiratory Society
https://www.readbyqxmd.com/read/14575177/septicaemic-melioidosis-in-a-tertiary-care-hospital-in-south-india
#11
Mary V Jesudason, Anand Anbarasu, T Jacob John
BACKGROUND & OBJECTIVES: Melioidosis and the causative organism Burkholderia pseudomallei are being recognized gradually in various centres in India. In the septicaemic form, melioidosis is a serious and life threatening condition which requires early detection and specific treatment to avoid case fatality. A review of patients with septicaemic melioidosis at a tertiary care hospital in south India was carried out with a view to define the clinical features, predisposing conditions, if any, and the outcome...
March 2003: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/12139377/serum-il-12-in-systemic-lupus-erythematosus-absence-of-p70-heterodimers-but-presence-of-p40-monomers-correlating-with-disease-activity
#12
B R Lauwerys, J Van Snick, F A Houssiau
Biologically active IL-12 is a 70 kDa heterodimeric cytokine (IL-12 p70) mainly produced by antigen-presenting cells (APC) and made of disulfide-linked alpha (p35) and beta (p40) chains. Since the production of the p40 subunit is independently regulated from that of IL-12 p70, we compared levels of p40 and IL-12 p70 in the sera of patients with systemic lupus erythematosus (SLE). Sera obtained from rheumatoid arthritis (RA) patients and healthy subjects were used as controls. Serum p40 titers were significantly higher in SLE patients (mean +/- s...
2002: Lupus
https://www.readbyqxmd.com/read/11821177/cardiobacterium-hominis-bioprosthetic-mitral-valve-endocarditis-presenting-as-septic-arthritis
#13
Anucha Apisarnthanarak, Raymond M Johnson, Alan C Braverman, William Michael Dunne, J Russell Little
We report an unusual case of Cardiobacterium hominis bioprosthetic valve endocarditis presenting as septic arthritis. This remarkable presentation had clinical features consistent with endocarditis generally associated with highly virulent pathogens. A literature search has failed to disclose a report of septic arthiritis as a manifestation of C. hominis endocarditis.
January 2002: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/10875323/septic-arthiritis-due-to-prevotella-bivia-in-a-patient-with-rheumatoid-arthritis
#14
J J Alegre-Sancho, X Juanola, F J Narvaez, D Roig-Escofet
Prevotella bivia is a gram-negative anaerobic bacteria traditionally classified in the genus Bacteroides, and usually reported in obstetric and gynecologic infections. To date, there has been only one description of infectious arthritis secondary to this germ. We report the first case of septic arthritis due to Prevotella bivia in a patient with severe, long-lasting rheumatoid arthritis (RA) treated with low doses of corticosteroids. RA is a well-known predisposing factor to septic arthritis, whose causes are multifactorial (general immunosuppression induced by the disease and its therapy, presence of prosthetic joints, etc...
2000: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/9458212/upregulation-of-cytokine-receptors-stnf-r55-stnf-r75-and-sil-2r-in-psoriatic-arthritis-synovial-fluid
#15
G Partsch, E Wagner, B F Leeb, A Dunky, G Steiner, J S Smolen
OBJECTIVE: To assess differences in soluble tumor necrosis factor receptor 55 (sTNF-R55), sTNF-R75, and soluble interleukin 2 receptor (sIL-2R) in synovial fluid (SF) of patients with psoriatic arthritis (PsA), a seronegative inflammatory joint disease, in comparison with those of patients with rheumatoid arthiritis (RA) and osteoarthritis (OA). METHODS: sIL-R were measured in SF with commercial sandwich ELISA and the results correlated with serological and clinical disease activity variables...
January 1998: Journal of Rheumatology
https://www.readbyqxmd.com/read/2755397/-the-hypophyseo-thyroid-system-in-psoriatic-arthritis-combined-with-chronic-opisthorchiasis
#16
S G Milevskaia, V G Borodulin, A V Lepekhin, V N Avdienko
Paper presents the data on the content of hypophysial-thyroid and hypophysial-adrenal systems' hormones obtained by means of radioimmune assay, and the data of timecourse hepatoscintibiligraphy with Tc 99 m TCK-15 of 94 patients (first group--48 patients with psoriatic arthiritis combined with chronic opisthorchiasis; second group--46 pure psoriatic arthritis patients). Statistically significant increase in the content of triiodinethyronine, thyroxine, hypophysial thyreotropic hormone, corticotropic hormone and significant reduction of cortizol and aldosteron contents were observed in case of mixed pathology...
March 1989: Meditsinskaia Parazitologiia i Parazitarnye Bolezni
https://www.readbyqxmd.com/read/682678/prospective-analysis-of-psoriatic-arthritis-in-patients-hospitalized-for-psoriasis
#17
D G Leonard, J D O'Duffy, R S Rogers
Among 77 patients hospitalized with psoriasis, 30 (39%) had psoriatic arthritis. Arthiritis was more frequent (P less than 0.05) in those with extensive psoriasis (grades 3 and 4) than in those with less extensive psoriasis (grade 1 and 2). Temporally, flares in skin and joint disease were not closely related. The Moll-Wright classification of psoriatic arthritis into five clinical groups could be loosely applied to our patients. However, sacroiliitis (present in 33% of the patients) was seen in all five groups and was related to HLA-B27 antigen...
August 1978: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/281717/self-nonself-concept-for-cancer-and-diseases-previously-known-as-autoimmune-diseases-illegitimate-transferases-plasma-exchange
#18
P Levine
The illegitimate glycosphingolipid antigens of the P blood group system and of the Forssman (Fs) tissue antigen in adenocarcinoma which are foreign to the host suggest the self-nonself concept which applies also to numerous other diseases such as rheumatoid arthritis, lupus, gluomerulonephritis, and idiopathic acute hemolytic anemia. In the presence of the glycosphingolipid antigens such as ABO, P, and Fs, the normal serum of the homozygote recessive precursor contains antibodies for the missing antigen(s)...
November 1978: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/214047/a-longitudinal-study-of-in-vitro-tests-for-lymphocyte-function-in-rheumatoid-arthritis
#19
J S Percy, P Davis, A S Russell, E Brisson
In vitro tests of lymphocyte function have been performed in 61 patients with ;classical' or ;definite' rheumatoid arthritis. In vitro lymphocyte function was assessed by lymphocyte transformation responses to phytohaemagglutinin (PHA), Pokeweed mitogen (PWM), Candida antigen, and herpes simplex type I (HSV1). Follow up data were available after 6 months of treatment in 32 of these patients. Spontaneous lymphocyte transformation was assessed in all patients. Results obtained in patients with rheumatoid arthiritis were compared to those seen in a normal control population...
October 1978: Annals of the Rheumatic Diseases
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