Post-traumatic thrombo embolism

OBJECTIVE: Virtual autopsy is a non-invasive/minimally invasive method for conducting an autopsy, with the assistance of imaging techniques. We aim to review the benefits of virtual autopsy in detecting pathologies in the paediatric population. METHOD: The procedure adhered to Institute of Medicine and Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. Seven databases including MEDLINE and SCOPUS were searched for articles published 2010-2020 worldwide in English...

BACKGROUND: Acute thrombosis of an abdominal aortic aneurysm with acute limb ischaemia is an unusual complication and is associated with high mortality. Dislocation of the intrasaccular mural thrombus could be one of the mechanisms. For the most part, acute limb ischaemia presents with absent pulses, compatible with the clinical findings, which include pain, paraesthesia, and paralysis. Herein, we report a rare condition with detectable distal pulses in advanced limb ischaemia due to poor perfusion caused by the dislocation of mural thrombus from an abdominal aortic aneurysm...

BACKGROUND: Optimal management of severe trauma patients with active hemorrhage relies on adequate initial resuscitation. Early administration of coagulation factors improves post-traumatic coagulation disorders, and four-factor prothrombin complex concentrate (PCC) might be useful in this context. Our main hypothesis is that four-factor PCC in addition to a massive transfusion protocol decreases blood product consumption at day 1 in severe trauma patients with major bleeding. METHODS: This is a prospective, randomized, multicenter, double-blind, parallel, controlled superiority trial...

Introduction: A 55 year old man who suffered from recurrent traumatic multi-organ bleeding presented with deterioration in kidney function and pulmonary embolism caused by a newly diagnosed renal vein thrombosis during hospitalisation. Report: Complete clot removal was performed successfully by catheter directed aspiration. Thrombotic emboli were captured in a temporary filter device. A post-interventional computed tomography scan showed full restoration of the occluded renal vein...

OBJECTIVE: MRI has highly changed the assessment of post-traumatic syringomyelia (PTS), roughly estimated at 30% nowadays. Times to onset (TTO) symptoms are random. This case report describes how hyperhidrosis appeared and revealed PTS diagnosis. OBSERVATIONS: Mr M., 43-year-old, is rehabilitation inpatient after T10 AIS A spinal cord injury (SCI). Three months after this event, Mr M complains of acute hyperhidrosis crisis always located below the injury, which can occur at any time of the day, particularly when he moves...

INTRODUCTION: Thrombo-embolic events after trauma are considered to be life-threatening complications. Our aim was to determine the incidence of arterial and venous thrombo-embolic events (TE) in severely-injured trauma patients, and its associated risk factors by using a large trauma registry. METHODS: Patients' data from the TraumaRegister DGU® (TR-DGU) were screened for TE (DVT [symptomatic deep vein thrombosis], PE [symptomatic pulmonary embolism], MI [myocardial infarction], and stroke) through the clinical course of severely injured adult trauma patients from January 2005 to December 2012...

Venous thrombo-embolism (VTE) is frequently encountered in critically ill neurological and neurosurgical patients admitted to intensive care units. This patient population includes those with brain neoplasm, intracranial hemorrhage, ischemic stroke, subarachnoid hemorrhage, pre- and post-operative patients undergoing neurosurgical procedures and those with traumatic brain injury, and acute spinal cord injury (SCI). There is a wide variability in clinical practice for thromboprophylaxis in these patients, in part due to paucity of data based on randomized clinical trials...

Post traumatic renal artery thrombosis is rarely described in the literature. This pathology can result from stretch injury to inelastic intima of the renal artery, or by the direct flow to the abdomen causing compression injury to the renal artery against the vertebral column. However, the association of this pathology with hematologic diseases (in particular protein C deficit) was never described. We report an observation of a 28-year-old man with an uneventful history who was admitted to the intensive care unit for traumatic head injury associated with post traumatic renal artery thrombosis requiring nephrectomy...

BACKGROUND: Symptomatic fibromuscular dysplasia (FMD) of the internal carotid artery (ICA) can present as thrombo-embolic ischemic events, spontaneous or post-traumatic dissection, aneurysmal degeneration or intracranial haemorrhage and needs definitive surgical treatment. PATIENTS AND METHODS: Six patients and nine ICA with FMD were revascularised using a carotid approach with minimal exposure of the common, external and internal carotid arteries for covered stent repair...

Aneurysmal dilatations occur at any level of carotid dissection, but typically at the distal subcranial segment. These aneurysms may grow, compress cervical structures, rupture or constitute a potential source of thrombo-embolic complications. When conservative and/or medical treatment failed or is contraindicated, a more aggressive therapy, such as endovascular stenting should be considered. We report the successful use endovascular stenting for the treatment of post-traumatic dissecting aneurysms of the extracranial internal carotid artery and discuss the potential of different stents types...

The occurrence of iatrogenous vascular accidents is underestimated. The authors describe 14 venous lesions to the femoro-iliac axis out of 60 iatrogenous vascular traumatisms. They consider the different aetiologies, underlining the disadvantages of femoral catheterisms and the main surgicalfactors contributing to venous traumatism. They emphasize the need for preventive measures in each discipline, and also the need for rapid diagnosis, thorough treatment, and careful post-operative after-care, bearing in mind secondary thrombo-embolic complications...

Twelve traumatic internal carotid artery dissections were seen within a three-year period. All dissections were diagnosed upon onset of neurological deficits, although, seen retrospectively, there had been warning signs such as partial Horner's syndrome and neck pain, in the majority of cases prior to the neurological deficits. Panangiography and transcranial Doppler ultrasound were used to assess the cerebral haemodynamic situation. In only 3 of the 12 cases evidence of insufficient collateral circulation to the compromised carotid artery distribution was found, but radiological and Doppler sonographic signs of embolism to the middle cerebral artery were seen in the majority of patients...

The incidence of pulmonary embolism was surveyed in 500 serial autopsy records (1984-1989) in Nagoya University Hospital. This disease occurred in 77 cases (15.4%) and acute fatal pulmonary embolism was the cause of death in 30 cases (6.0%). This incidence was higher than has previously been reported in Japan, and almost the same as the incidence reported is USA or Western Europe. Thromboembolism was the major cause of this phenomenon in our series. Thirty-four cases were thrombo-embolized. Venous thrombi in 15 cases resulted from intravenous catheter...