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https://www.readbyqxmd.com/read/28637077/-tracheostomy-home-care-of-patients-after-long-term-ventilation-on-the-icu-a-position-paper
#1
(no author information available yet)
No abstract text is available yet for this article.
June 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28596060/-medical-prevention-and-treatment-of-radiation-induced-pulmonary-complications
#2
A Vallard, C Rancoule, H Le Floch, J-B Guy, S Espenel, C Le Péchoux, É Deutsch, N Magné, C Chargari
Radiation-induced lung injuries mainly include the (acute or sub-acute) radiation pneumonitis, the lung fibrosis and the bronchiolitis obliterans organizing pneumonia (BOOP). The present review aims at describing the diagnostic process, the current physiopathological knowledge, and the available (non dosimetric) preventive and curative treatments. Radiation-induced lung injury is a diagnosis of exclusion, since clinical, radiological, or biological pathognomonic evidences do not exist. Investigations should necessarily include a thoracic high resolution CT-scan and lung function tests with a diffusing capacity of the lung for carbon monoxide...
June 5, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28573440/-quality-assurance-of-optical-coherence-tomography-for-diagnostics-of-the-fundus-positional-statement-of-the-bva-dog-and-rg
#3
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28573343/-preoperative-evaluation-of-adult-patients-before-elective-noncardiothoracic-surgery-joint-recommendation-of-the-german-society-of-anesthesiology-and-intensive-care-medicine-the-german-society-of-surgery-and-the-german-society-of-internal-medicine
#4
B Zwissler
Evaluation of the patient's medical history and a physical examination are the cornerstones of risk assessment prior to elective surgery and may help to optimize the patient's preoperative medical condition and to guide perioperative management. Whether the performance of additional technical tests (e. g. blood chemistry, ECG, spirometry, chest x‑ray) can contribute to a reduction of perioperative risk is often not very well known or is controversial. Similarly, there is considerable uncertainty among anesthesiologists, internists and surgeons with respect to the perioperative management of the patient's long-term medication...
June 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28566218/relations-between-lipoprotein-a-concentrations-lpa-genetic-variants-and-the-risk-of-mortality-in-patients-with-established-coronary-heart-disease-a-molecular-and-genetic-association-study
#5
Stephen Zewinger, Marcus E Kleber, Vinicius Tragante, Raymond O McCubrey, Amand F Schmidt, Kenan Direk, Ulrich Laufs, Christian Werner, Wolfgang Koenig, Dietrich Rothenbacher, Ute Mons, Lutz P Breitling, Herrmann Brenner, Richard T Jennings, Ioannis Petrakis, Sarah Triem, Mira Klug, Alexandra Filips, Stefan Blankenberg, Christoph Waldeyer, Christoph Sinning, Renate B Schnabel, Karl J Lackner, Efthymia Vlachopoulou, Ottar Nygård, Gard Frodahl Tveitevåg Svingen, Eva Ringdal Pedersen, Grethe S Tell, Juha Sinisalo, Markku S Nieminen, Reijo Laaksonen, Stella Trompet, Roelof A J Smit, Naveed Sattar, J Wouter Jukema, Heinrich V Groesdonk, Graciela Delgado, Tatjana Stojakovic, Anna P Pilbrow, Vicky A Cameron, A Mark Richards, Robert N Doughty, Yan Gong, Rhonda Cooper-DeHoff, Julie Johnson, Markus Scholz, Frank Beutner, Joachim Thiery, J Gustav Smith, Ragnar O Vilmundarson, Ruth McPherson, Alexandre F R Stewart, Sharon Cresci, Petra A Lenzini, John A Spertus, Oliviero Olivieri, Domenico Girelli, Nicola I Martinelli, Andreas Leiherer, Christoph H Saely, Heinz Drexel, Axel Mündlein, Peter S Braund, Christopher P Nelson, Nilesh J Samani, Daniel Kofink, Imo E Hoefer, Gerard Pasterkamp, Arshed A Quyyumi, Yi-An Ko, Jaana A Hartiala, Hooman Allayee, W H Wilson Tang, Stanley L Hazen, Niclas Eriksson, Claes Held, Emil Hagström, Lars Wallentin, Axel Åkerblom, Agneta Siegbahn, Igor Karp, Christopher Labos, Louise Pilote, James C Engert, James M Brophy, George Thanassoulis, Peter Bogaty, Wojciech Szczeklik, Marcin Kaczor, Marek Sanak, Salim S Virani, Christie M Ballantyne, Vei-Vei Lee, Eric Boerwinkle, Michael V Holmes, Benjamin D Horne, Aroon Hingorani, Folkert W Asselbergs, Riyaz S Patel, Bernhard K Krämer, Hubert Scharnagl, Danilo Fliser, Winfried März, Thimoteus Speer
BACKGROUND: Lipoprotein(a) concentrations in plasma are associated with cardiovascular risk in the general population. Whether lipoprotein(a) concentrations or LPA genetic variants predict long-term mortality in patients with established coronary heart disease remains less clear. METHODS: We obtained data from 3313 patients with established coronary heart disease in the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. We tested associations of tertiles of lipoprotein(a) concentration in plasma and two LPA single-nucleotide polymorphisms ([SNPs] rs10455872 and rs3798220) with all-cause mortality and cardiovascular mortality by Cox regression analysis and with severity of disease by generalised linear modelling, with and without adjustment for age, sex, diabetes diagnosis, systolic blood pressure, BMI, smoking status, estimated glomerular filtration rate, LDL-cholesterol concentration, and use of lipid-lowering therapy...
May 26, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28522277/-immunotherapy-and-radiotherapy
#6
S Bockel, D Antoni, É Deutsch, F Mornex
Radiotherapy, primarily known for its cytotoxic effect on the tumor cells, via the induction of DNA damages, has the ability to induce a systemic antitumoral response. By an immunologic cell death, tumor cells exposed to radiation release a large amount of neoantigenes and pro-inflammatory mediators, acting as an in situ vaccine, resulting in an tumor regression within the primary irradiated site, but also in the distant "out of field" secondary tumors. However, this phenomenon is extremly rare with radiotherapy alone, suggesting that the radiation-induced antitumor immunity is not sufficient for overcoming the tumor's and its microenvironnement immunosuppressing effect...
May 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28483649/effect-of-nascent-peptide-steric-bulk-on-elongation-kinetics-in-the-ribosome-exit-tunnel
#7
Pengse Po, Erin Delaney, Howard Gamper, D Miklos Szantai-Kis, Lee Speight, LiWei Tu, Andrey Kosolapov, E James Petersson, Ya-Ming Hou, Carol Deutsch
All proteins are synthesized by the ribosome, a macromolecular complex that accomplishes the life-sustaining tasks of faithfully decoding mRNA and catalyzing peptide bond formation at the peptidyl transferase center (PTC). The ribosome has evolved an exit tunnel to host the elongating new peptide, protect it from proteolytic digestion, and guide its emergence. It is here that the nascent chain begins to fold. This folding process depends on the rate of translation at the PTC. We report here that besides PTC events, translation kinetics depend on steric constraints on nascent peptide side chains and that confined movements of cramped side chains within and through the tunnel fine-tune elongation rates...
May 5, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28482371/guidelines-for-the-treatment-of-head-injury-in-adults
#8
R Firsching, E Rickels, U M Mauer, O W Sakowitz, M Messing-Jünger, K Engelhard, P Schwenkreis, J Linn, K Schwerdtfeger
The workshop of scientific medical faculties (Arbeitsgemeinschaft wissenschaftlicher medizinischer Fakultäten [AWMF]) of Germany has asked societies of specific medical disciplines to jointly publish guidelines on the treatment of diseases and injuries. On behalf of the Deutsche Gesellschaft für Neurochirurgie, its commission on guidelines initiated an interdisciplinary approach to publish guidelines on the treatment of head injury in adults. These guidelines were published in German by the AWMF in late 2015...
May 8, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28464934/study-protocol-of-the-german-study-on-tobacco-use-debra-a-national-household-survey-of-smoking-behaviour-and-cessation
#9
Sabrina Kastaun, Jamie Brown, Leonie S Brose, Elena Ratschen, Tobias Raupach, Dennis Nowak, Constanze Cholmakow-Bodechtel, Lion Shahab, Robert West, Daniel Kotz
BACKGROUND: The prevalence of tobacco smoking in Germany is high (~27%). Monitoring of national patterns of smoking behaviour and data on the "real-world" effectiveness of cessation methods are needed to inform policies and develop campaigns aimed at reducing tobacco-related harm. In England, the Smoking Toolkit Study (STS) has been tracking such indicators since 2006, resulting in the adaptation of tobacco control policies. However, findings cannot be directly transferred into the German health policy context...
May 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28458182/the-attribution-of-animacy-and-agency-in-frontotemporal-dementia-versus-alzheimer-s-disease
#10
Sylvia S Fong, Pongsatorn Paholpak, Madelaine Daianu, Mariel B Deutsch, Brandalyn C Riedel, Andrew R Carr, Elvira E Jimenez, Michelle M Mather, Paul M Thompson, Mario F Mendez
Impaired attribution of animacy (state of living or being sentient) and of agency (capability of intrinsically-driven action) may underlie social behavior disturbances in behavioral variant frontotemporal dementia (bvFTD). We presented the Heider and Simmel film of moving geometric shapes to 11 bvFTD patients, 11 Alzheimer's disease (AD) patients, and 12 healthy controls (HCs) and rated their recorded verbal responses for animacy attribution and agency attribution. All participants had skin conductance (SC) continuously recorded while viewing the film, and all dementia participants underwent magnetic resonance imaging (MRI) for regions of interest...
April 8, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28423417/multi-species-mating-disruption-in-cranberries-ericales-ericaceae-early-evidence-using-a-flowable-emulsion
#11
Shawn A Steffan, Elissa M Chasen, Annie E Deutsch, Agenor Mafra-Neto
Pheromone-based mating disruption has proven to be a powerful pest management tactic in many cropping systems. However, in the cranberry system, a viable mating disruption program does not yet exist. There are commercially available pheromones for several of the major pests of cranberries, including the cranberry fruitworm, Acrobasis vaccinii Riley (Lepidoptera: Pyralidae) and blackheaded fireworm, Rhopobota naevana (Hübner) (Lepidoptera: Tortricidae). Previous studies have shown that mating disruption represents a promising approach for R...
January 1, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/28421285/-erratum-to-guidelines-from-the-dog-rg-and-bva-retinal-artery-occlusion-november-2016-status
#12
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28407673/-tracheostomy-home-care-of-patients-after-long-term-ventilation-on-the-icu-a-position-paper
#13
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Pneumologie
https://www.readbyqxmd.com/read/28405759/-statement-of-the-professional-association-of-german-ophthalmologists-bva-the-german-ophthalmological-society-dog-and-the-german-retina-society-rg-oct-angiography-in-germany-presentation-nomenclature-and-future-plans-situation-january-2017
#14
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28363728/pelvic-radiotherapy-in-the-setting-of-rheumatoid-arthritis-refining-the-paradigm
#15
T Felefly, R Mazeron, A Huertas, C H Canova, P Maroun, M Kordahi, P Morice, É Deutsch, C Haie-Méder, C Chargari
PURPOSE: Conflicting results concerning the toxicity of radiotherapy in the setting of rheumatoid arthritis were reported in literature. This work describes the toxicity profiles of patients with rheumatoid arthritis undergoing pelvic radiotherapy for gynecologic malignancies at our institution. PATIENTS AND METHODS: Charts of patients with rheumatoid arthritis who underwent pelvic radiotherapy for cervical or endometrial cancer in a curative intent at the Gustave-Roussy Cancer Campus between 1990 and 2015 were reviewed for treatment-related toxicities...
April 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28355665/transorbitale-wechselstromstimulation-bei-optikusatrophie-dezember-2016
#16
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28260956/in-flight-medical-emergencies-during-airline-operations-a-survey-of-physicians-on-the-incidence-nature-and-available-medical-equipment
#17
Jochen Hinkelbein, Christopher Neuhaus, Lennert Böhm, Steffen Kalina, Stefan Braunecker
BACKGROUND: Data on the incidence of in-flight medical emergencies on-board civil aircraft are uncommon and rarely published. Such data could provide information regarding required medical equipment on-board aircraft and requisite training for cabin crew. The aim of the present study was to gather data on the incidences, nature, and medical equipment for in-flight medical emergencies by way of a survey of physician members of a German aerospace medical society. MATERIALS AND METHODS: Using unipark...
2017: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/28249612/do-selective-radiation-dose-escalation-and-tumour-hypoxia-status-impact-the-loco-regional-tumour-control-after-radio-chemotherapy-of-head-neck-tumours-the-escalox-protocol
#18
Steffi U Pigorsch, Jan J Wilkens, Severin Kampfer, Victoria Kehl, Alexander Hapfelmeier, Christian Schläger, Henning Bier, Markus Schwaiger, Stephanie E Combs
BACKGROUND: Standard of care primary treatment of carcinoma of locally advanced squamous cell head and neck cancer (LAHNSCC) consists of platinum-based concomitant chemo-irradiation. Despite progress in the treatment of LAHNSCC using modern radiotherapy techniques the outcome remains still poor. Using IMRT with SIB the escalation of total dose to the GTV is possible with the aim to improve clinical outcome. This study tests the hypothesis if radiation dose escalation to the GTV improves 2-year-LRC and -OS after concomitant chemo-irradiation...
March 1, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28245642/flight-synchrony-among-the-major-moth-pests-of-cranberries-in-the-upper-midwest-usa
#19
Shawn A Steffan, Merritt E Singleton, Jayne Sojka, Elissa M Chasen, Annie E Deutsch, Juan E Zalapa, Christelle Guédot
The cranberry fruitworm (Acrobasis vaccinii Riley), sparganothis fruitworm (Sparganothis sulfureana Clemens), and blackheaded fireworm (Rhopobota naevana Hübner) are historically significant pests of cranberries (Vaccinium macrocarpon Aiton) in the Upper Midwest (Wisconsin), USA. Their respective natural histories are well documented but correlations between developmental benchmarks (e.g., larval eclosion) and degree-day accruals are not yet known. Treatment timings are critical to the optimization of any given control tactic, and degree-day accrual facilitates optimization by quantifying the developmental status of pest populations...
February 26, 2017: Insects
https://www.readbyqxmd.com/read/28222477/checklists-for-the-assessment-of-correct-inhalation-therapy
#20
V Knipel, S Schwarz, F S Magnet, J H Storre, C P Criée, W Windisch
Introduction For the long-term treatment of obstructive lung diseases inhalation therapy with drugs being delivered directly to the lungs as an aerosol has become the method of choice. However, patient-related mistakes in inhalation techniques are frequent and recognized to be associated with reduced disease control. Since the assessment of patient-mistakes in inhalation has yet not been standardized, the present study was aimed at developing checklists for the assessment of correct inhalation. Methods Checklists were developed in German by an expert panel of pneumologists and professionally translated into English following back-translation procedures...
February 2017: Pneumologie
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