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https://www.readbyqxmd.com/read/28260956/in-flight-medical-emergencies-during-airline-operations-a-survey-of-physicians-on-the-incidence-nature-and-available-medical-equipment
#1
Jochen Hinkelbein, Christopher Neuhaus, Lennert Böhm, Steffen Kalina, Stefan Braunecker
BACKGROUND: Data on the incidence of in-flight medical emergencies on-board civil aircraft are uncommon and rarely published. Such data could provide information regarding required medical equipment on-board aircraft and requisite training for cabin crew. The aim of the present study was to gather data on the incidences, nature, and medical equipment for in-flight medical emergencies by way of a survey of physician members of a German aerospace medical society. MATERIALS AND METHODS: Using unipark...
2017: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/28249612/do-selective-radiation-dose-escalation-and-tumour-hypoxia-status-impact-the-loco-regional-tumour-control-after-radio-chemotherapy-of-head-neck-tumours-the-escalox-protocol
#2
Steffi U Pigorsch, Jan J Wilkens, Severin Kampfer, Victoria Kehl, Alexander Hapfelmeier, Christian Schläger, Henning Bier, Markus Schwaiger, Stephanie E Combs
BACKGROUND: Standard of care primary treatment of carcinoma of locally advanced squamous cell head and neck cancer (LAHNSCC) consists of platinum-based concomitant chemo-irradiation. Despite progress in the treatment of LAHNSCC using modern radiotherapy techniques the outcome remains still poor. Using IMRT with SIB the escalation of total dose to the GTV is possible with the aim to improve clinical outcome. This study tests the hypothesis if radiation dose escalation to the GTV improves 2-year-LRC and -OS after concomitant chemo-irradiation...
March 1, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28245642/flight-synchrony-among-the-major-moth-pests-of-cranberries-in-the-upper-midwest-usa
#3
Shawn A Steffan, Merritt E Singleton, Jayne Sojka, Elissa M Chasen, Annie E Deutsch, Juan E Zalapa, Christelle Guédot
The cranberry fruitworm (Acrobasis vaccinii Riley), sparganothis fruitworm (Sparganothis sulfureana Clemens), and blackheaded fireworm (Rhopobota naevana Hübner) are historically significant pests of cranberries (Vaccinium macrocarpon Aiton) in the Upper Midwest (Wisconsin), USA. Their respective natural histories are well documented but correlations between developmental benchmarks (e.g., larval eclosion) and degree-day accruals are not yet known. Treatment timings are critical to the optimization of any given control tactic, and degree-day accrual facilitates optimization by quantifying the developmental status of pest populations...
February 26, 2017: Insects
https://www.readbyqxmd.com/read/28222477/checklists-for-the-assessment-of-correct-inhalation-therapy
#4
V Knipel, S Schwarz, F S Magnet, J H Storre, C P Criée, W Windisch
Introduction For the long-term treatment of obstructive lung diseases inhalation therapy with drugs being delivered directly to the lungs as an aerosol has become the method of choice. However, patient-related mistakes in inhalation techniques are frequent and recognized to be associated with reduced disease control. Since the assessment of patient-mistakes in inhalation has yet not been standardized, the present study was aimed at developing checklists for the assessment of correct inhalation. Methods Checklists were developed in German by an expert panel of pneumologists and professionally translated into English following back-translation procedures...
February 2017: Pneumologie
https://www.readbyqxmd.com/read/28183812/new-guidelines-for-publication-of-manuscripts-describing-development-and-application-of-targeted-mass-spectrometry-measurements-of-peptides-and-proteins
#5
Susan E Abbatiello, Bradley L Ackermann, Christoph H Borchers, Ralph A Bradshaw, Steven A Carr, Robert J Chalkley, Meena Choi, Eric W Deutsch, Bruno Domon, Andrew N Hoofnagle, Hasmik Keshishian, Eric Kuhn, Daniel C Liebler, Michael J MacCoss, Brendan MacLean, D R Mani, Hendrik Neubert, Derek Smith, Olga Vitek, Lisa Zimmerman
Molecular & Cellular Proteomics is pleased to announce new guidelines and requirements for papers describing the development and application of targeted mass spectrometry measurements of peptides, modified peptides and proteins. These guidelines will be implemented for papers submitted starting June, 2017.
February 9, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28168275/promises-and-challenges-for-the-implementation-of-computational-medical-imaging-radiomics-in-oncology
#6
E J Limkin, R Sun, L Dercle, E I Zacharaki, C Robert, S Reuzé, A Schernberg, N Paragios, E Deutsch, C Ferté
No abstract text is available yet for this article.
February 7, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28160122/-guidelines-from-the-dog-rg-and-bva-retinal-artery-occlusion-november-2016-status
#7
(no author information available yet)
No abstract text is available yet for this article.
February 3, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28149707/virucidal-efficacy-of-a-sonicated-hydrogen-peroxide-system-trophon-%C3%A2-epr-following-european-and-german-test-methods
#8
Britta Becker, Birte Bischoff, Florian H H Brill, Eike Steinmann, Jochen Steinmann
Aim: The virucidal efficacy of an automated ultrasound probe disinfector (trophon(®) EPR) was evaluated in a three step procedure according to European and German test methods. This system uses sonicated hydrogen peroxide mist (35%) at elevated temperature (50°C) in a closed chamber with control of all parameters within a 7 minute cycle. Methods: In the first step of examination, the peroxide solution was tested in a quantitative suspension assay according to the Guideline of Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten (DVV) e...
2017: GMS Hygiene and Infection Control
https://www.readbyqxmd.com/read/28144738/-transorbital-alternating-current-in-optic-neuropathy-december-2016-opinion-of-the-dog-and-bva-on-gall%C3%A2-c-et%C3%A2-al-alternating-current-stimulation-for-vision-restoration-after-optic-nerve-damage-a%C3%A2-randomized-clinical-trial-plos-one-2016
#9
(no author information available yet)
No abstract text is available yet for this article.
January 31, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28128609/quantum-steering-inequality-with-tolerance-for-measurement-setting-errors-experimentally-feasible-signature-of-unbounded-violation
#10
Adam Rutkowski, Adam Buraczewski, Paweł Horodecki, Magdalena Stobińska
Quantum steering is a relatively simple test for proving that the values of quantum-mechanical measurement outcomes come into being only in the act of measurement. By exploiting quantum correlations, Alice can influence-steer-Bob's physical system in a way that is impossible in classical mechanics, as shown by the violation of steering inequalities. Demonstrating this and similar quantum effects for systems of increasing size, approaching even the classical limit, is a long-standing challenging problem. Here, we prove an experimentally feasible unbounded violation of a steering inequality...
January 13, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28114709/-statement-of-the-german-airway-league-pharmacotherapy-register-of-the-federal-association-of-the-statutory-health-care-physicians-an-attempt-against-the-personalized-medicine
#11
https://www.readbyqxmd.com/read/28114192/fda-benchmark-medical-device-flow-models-for-cfd-validation
#12
Richard A Malinauskas, Prasanna Hariharan, Steven W Day, Luke H Herbertson, Martin Buesen, Ulrich Steinseifer, Kenneth I Aycock, Bryan C Good, Steven Deutsch, Keefe B Manning, Brent A Craven
Computational fluid dynamics (CFD) is increasingly being used to develop blood-contacting medical devices. However, the lack of standardized methods for validating CFD simulations and blood damage predictions limits its use in the safety evaluation of devices. Through a U.S. Food and Drug Administration (FDA) initiative, two benchmark models of typical device flow geometries (nozzle and centrifugal blood pump) were tested in multiple laboratories to provide experimental velocities, pressures, and hemolysis data to support CFD validation...
March 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28033623/-consensus-of-the-deutsche-gesellschaft-der-plastischen-rekonstruktiven-und-%C3%A3-sthetischen-chirurgen-dgpr%C3%A3-c-on-autologous-fat-grafting
#13
R E Giunta, R E Horch, L Prantl, E M Baur, C Herold, L Kamolz, M Lehnhardt, E M Noah, O Rennekampff, D Richter, D J Schaefer, K Ueberreiter
On occasion of the Munich Plastic Symposium in Munich the board of the Deutsche Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC) together with a group of experts who were also involved in the preparation of the recently published S2K guideline "Autologous Fat Grafting", prepared a consensus statement from a plastic-surgical point of view so to evaluate current spects and taking into account the current legal framework: 1. Autologous Fat Grafting is a long established treatment in plastic surgery and does not differ from other tissue grafts...
December 2016: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28025611/evidence-and-evidence-gaps-an-introduction
#14
REVIEW
Gabriele Dreier, Jan Löhler
Background: Medical treatment requires the implementation of existing evidence in the decision making process in order to be able to find the best possible diagnostic, therapeutic or prognostic measure for the individual patient based on the physician's own expertise. Clinical trials form the evidence base and ideally, their results are assembled, analyzed, summarized, and made available in systematic review articles. Beside planning, conducting, and evaluating clinical trials in conformity with GCP (good clinical practice), it is essential that all results of conducted studies are publicly available in order to avoid publication bias...
2016: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/28024689/alk-testing-in-non-small-cell-lung-cancer-nsclc-immunohistochemistry-ihc-and-or-fluorescence-in-situ-hybridisation-fish-statement-of-the-germany-society-for-pathology-dgp-and-the-working-group-thoracic-oncology-aio-of-the-german-cancer-society-e-v-stellungnahme
#15
M von Laffert, P Schirmacher, A Warth, W Weichert, R Büttner, R M Huber, J Wolf, F Griesinger, M Dietel, Ch Grohé
The EML4-ALK pathway plays an important role in a significant subset of non-small cell lung cancer patients. Treatment options such as ALK tyrosine kinase inhibitors lead to improved progression free survival and overall survival. These therapeutic options are chosen on the basis of the identification of the underlying genetic signature of the EML-ALK translocation. Efficient and easily accessible testing tools are required to identify eligible patients in a timely fashion. While FISH techniques are commonly used to detect this translocation, the broad implementation of this type of ALK testing into routine diagnostics is not optimal due to technical, structural and financial reasons...
January 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28007109/trypan-blue-as-a-surgical-adjunct-in-pediatric-cataract-surgery
#16
Gabrielle Fridman, Allison E Rizzuti, Jewel Liao, Mark Rolain, James A Deutsch, Stephen C Kaufman
PURPOSE: To study the effect of trypan blue on lens capsule elasticity and ease of completing a continuous curvilinear capsulorhexis (CCC) in a sheep lens model and to subsequently observe the effects of trypan blue in the surgical setting of 3 pediatric patients. SETTING: State University of New York, Downstate Medical Center, Brooklyn, New York, USA. DESIGN: Prospective case series. METHODS: Twenty-four lenses were excised from fresh sheep globes...
December 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27943610/covalent-surface-modification-of-gallium-arsenide-photocathodes-for-water-splitting-in-highly-acidic-electrolyte
#17
Logan E Garner, K Xerxes Steirer, James L Young, Nicholas C Anderson, Elisa M Miller, Jonathan S Tinkham, Todd G Deutsch, Alan Sellinger, John A Turner, Nathan R Neale
Efficient water splitting using light as the only energy input requires stable semiconductor electrodes with favorable energetics for the water-oxidation and proton-reduction reactions. Strategies to tune electrode potentials using molecular dipoles adsorbed to the semiconductor surface have been pursued for decades but are often based on weak interactions and quickly react to desorb the molecule under conditions relevant to sustained photoelectrolysis. Here, we show that covalent attachment of fluorinated, aromatic molecules to p-GaAs(1 0 0) surfaces can be employed to tune the photocurrent onset potentials of p-GaAs(1 0 0) photocathodes and reduce the external energy required for water splitting...
December 12, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27879066/xxix-%C3%A2-symposium-augustanum-jahrestagung-der-deutsch-italienischen-gesellschaft-f%C3%A3-r-dermatologie-e-%C3%A2-v-in-genua-am-27-%C3%A2-mai%C3%A2-2016
#18
Claudio Feliciani, Michael Hertl, Bernd-Rüdiger Balda
No abstract text is available yet for this article.
November 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27871334/exploiting-members-of-the-bahd-acyltransferase-family-to-synthesize-multiple-hydroxycinnamate-and-benzoate-conjugates-in-yeast
#19
Aymerick Eudes, Maxence Mouille, David S Robinson, Veronica T Benites, George Wang, Lucien Roux, Yi-Lin Tsai, Edward E K Baidoo, Tsan-Yu Chiu, Joshua L Heazlewood, Henrik V Scheller, Aindrila Mukhopadhyay, Jay D Keasling, Samuel Deutsch, Dominique Loqué
BACKGROUND: BAHD acyltransferases, named after the first four biochemically characterized enzymes of the group, are plant-specific enzymes that catalyze the transfer of coenzyme A-activated donors onto various acceptor molecules. They are responsible for the synthesis in plants of a myriad of secondary metabolites, some of which are beneficial for humans either as therapeutics or as specialty chemicals such as flavors and fragrances. The production of pharmaceutical, nutraceutical and commodity chemicals using engineered microbes is an alternative, green route to energy-intensive chemical syntheses that consume petroleum-based precursors...
November 21, 2016: Microbial Cell Factories
https://www.readbyqxmd.com/read/27834580/nkg2d-ligand-expression-in-pediatric-brain-tumors
#20
Kristen Haberthur, Kathryn Brennan, Virginia Hoglund, Stephanie Balcaitis, Harrison Chinn, Amira Davis, Shannon Kreuser, Conrad Winter, Sarah E S Leary, Gail H Deutsch, Richard G Ellenbogen, Courtney A Crane
Adult brain tumors establish an immunosuppressive tumor microenvironment as a modality of immune escape, with several immunotherapies designed to overcome this barrier. However, the relationship between tumor cells and immune cells in pediatric brain tumor patients is not as well-defined. In this study, we sought to determine whether the model of immune escape observed in adult brain tumors is reflected in patients with pediatric brain tumors by evaluating NKG2D ligand expression on tissue microarrays created from patients with a variety of childhood brain tumor diagnoses, and infiltration of Natural Killer and myeloid cells...
December 2016: Cancer Biology & Therapy
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