keyword
MENU ▼
Read by QxMD icon Read
search

Cut

keyword
https://www.readbyqxmd.com/read/28550807/effects-of-waterborne-copper-delivered-under-two-different-exposure-and-salinity-regimes-on-osmotic-and-ionic-regulation-in-the-mudflat-fiddler-crab-minuca-rapax-ocypodidae-brachyura
#1
Mariana V Capparelli, John C McNamara, Martin Grosell
The effects of exposure to copper (Cu) on tissue Cu accumulation, on hemolymph osmotic, Na(+) and Cl(-) regulation, and on gill Na(+)/K(+)-ATPase (NKA) and carbonic anhydrase (CA) activities were evaluated in the fiddler crab Minuca rapax. Waterborne copper was delivered to the crabs at one of three salinities (seawater at 25‰ salinity [S] = isosmotic control; distilled water [<0.1‰ S] = hypo-osmotic medium; or 60‰ S = hyper-osmotic seawater) either for 5 days in a 0.5-cm water film containing 0, 50, 150, 250 or 500µg Cu/L with free access to a dry surface, or in crabs fully submerged for 5h at 0, 250 or 500µg Cu/L...
May 24, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28550716/ex-vivo-measurement-of-scalp-follicular-infundibulum-delivery-of-zinc-pyrithione-and-climbazole-from-an-anti-dandruff-shampoo
#2
Guoqiang Chen, Chengdong Ji, Miao Miao, Kang Yang, Yajun Luo, Michael Hoptroff, Luisa Z Collins, Hans-Gerd Janssen
Efficient delivery of anti-dandruff (AD) actives into the scalp follicular infundibulum as well as onto the scalp surface is critical for the efficacy of AD shampoos. A method involving scalp cyanoacrylate (CA) biopsy sampling, a tailor made cutting device, ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) analysis, scanning electron microscopy (SEM) measurement and Raman imaging has been developed for the measurement of delivery of zinc pyrithione (ZPT) and climbazole (CBZ) from an AD shampoo into the scalp follicular infundibulum...
May 17, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28550609/validation-of-the-taps-1-a-four-item-screening-tool-to-identify-unhealthy-substance-use-in-primary-care
#3
Jan Gryczynski, Jennifer McNeely, Li-Tzy Wu, Geetha A Subramaniam, Dace S Svikis, Lauretta A Cathers, Gaurav Sharma, Jacqueline King, Eve Jelstrom, Courtney D Nordeck, Anjalee Sharma, Shannon G Mitchell, Kevin E O'Grady, Robert P Schwartz
BACKGROUND: The Tobacco, Alcohol, Prescription Medication, and Other Substance use (TAPS) tool is a combined two-part screening and brief assessment developed for adult primary care patients. The tool's first-stage screening component (TAPS-1) consists of four items asking about past 12-month use for four substance categories, with response options of never, less than monthly, monthly, weekly, and daily or almost daily. OBJECTIVE: To validate the TAPS-1 in primary care patients...
May 26, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28550587/epicardial-adipose-tissue-is-associated-with-high-risk-plaque-feature-progression-in-non-culprit-lesions
#4
Yahang Tan, Jia Zhou, Ying Zhou, Xiaobo Yang, Jing Wang, Yundai Chen
Several studies have suggested a link between epicardial adipose tissue (EAT) volume and high-risk plaques (HRPs); however, little is known about the association between EAT volume and HRP progression in non-culprit lesions (NCLs). Therefore, we evaluated whether EAT can independently predict HRP characteristic progression in NCLs by coronary computed tomography angiography (CCTA). In this single-centre trial, we analysed 131 consecutive patients (median age 61 years, male 72.52%) undergoing CCTA with percutaneous coronary intervention (PCI) for culprit lesions...
May 26, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28550204/cutting-edge-origins-recruitment-and-regulation-of-cd11c-cells-in-inflamed-islets-of-autoimmune-diabetes-mice
#5
Joanna E Klementowicz, Ashley E Mahne, Allyson Spence, Vinh Nguyen, Ansuman T Satpathy, Kenneth M Murphy, Qizhi Tang
In NOD mice, CD11c(+) cells increase greatly with islet inflammation and contribute to autoimmune destruction of pancreatic β cells. In this study, we investigated their origin and mechanism of recruitment. CD11c(+) cells in inflamed islets resembled classical dendritic cells based on their transcriptional profile. However, the majority of these cells were not from the Zbtb46-dependent dendritic-cell lineage. Instead, monocyte precursors could give rise to CD11c(+) cells in inflamed islets. Chemokines Ccl5 and Ccl8 were persistently elevated in inflamed islets and the influx of CD11c(+) cells was partially dependent on their receptor Ccr5...
May 26, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28550167/prediction-of-response-to-sorafenib-in-hepatocellular-carcinoma-a-marker-panel-by-multiple-reaction-monitoring-mass-spectrometry
#6
Hyunsoo Kim, Su Jong Yu, Injun Yeo, Young Youn Cho, Dong Hyeon Lee, Yuri Cho, Eun Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Sungyoung Lee, Jongsoo Jun, Taesung Park, Jung-Hwan Yoon, Youngsoo Kim
Sorafenib is the only standard treatment for unresectable hepatocellular carcinoma (HCC), but it provides modest survival benefits over placebo, necessitating predictive biomarkers of the response to sorafenib. Serum samples were obtained from 115 consecutive patients with HCC before sorafenib treatment and analyzed by multiple reaction monitoring-mass spectrometry (MRM-MS) and ELISA to quantify candidate biomarkers. We verified a triple-marker panel to be predictive of the response to sorafenib by MRM-MS, comprising CD5 antigen-like (CD5L), immunoglobulin J (IGJ), and galectin-3-binding protein (LGALS3BP), in HCC patients...
May 26, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28550010/statins-for-primary-prevention-in-older-people-do-not-cut-mortality-or-chd-events-study-finds
#7
Susan Mayor
No abstract text is available yet for this article.
May 25, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28549945/validity-of-the-rheumatoid-arthritis-impact-of-disease-raid-score-and-definition-of-cut-off-points-for-disease-activity-states-in-a-population-based-european-cohort-of-patients-with-rheumatoid-arthritis
#8
Fausto Salaffi, Marco Di Carlo, Jelena Vojinovic, Angela Tincani, Alberto Sulli, Stefano Soldano, Laura Andreoli, Francesca Dall'Ara, Ruxandra Ionescu, Katarina Simić Pašalić, Ineta Balčune, Iván Ferraz-Amaro, Malgorzata Tlustochowicz, Irena Butrimienė, Egle Punceviciene, Natalia Toroptsova, Simeon Grazio, Jadranka Morović-Vergles, Pavol Masaryk, Kati Otsa, Miguel Bernardes, Vladimira Boyadzhieva, Maurizio Cutolo
OBJECTIVES: To assess the validity of the Rheumatoid Arthritis Impact of Disease (RAID) for measuring disease activity of rheumatoid arthritis (RA), and to determine cut-off values for defining the disease activity states. METHODS: 622 RA patients from an European database have been included. Cross-validation was based on assessment of convergent and discriminant validity. Optimal cut-offs were determined against external criteria by calculating the respective 25(th) and 75(th) percentiles mean values of RAID...
May 23, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28549549/freezing-preparation-for-macroscopic-forensic-investigation-in-putrefied-brain
#9
Kotaro Matoba, Hideki Hyodoh, Manabu Murakami, Tomoko Matoba, Atsuko Saito, Fei Feng, Shigeki Jin
PURPOSE: To evaluate the usefulness of the applied freezing technique in putrefied brain for macroscopic investigation. MATERIALS AND METHODS: From October 2015 to September 2016, first the brains of 10 cadavers (control group: male 6, female 4, age 20-80 (mean 61.5), postmortem intervals (PMI) 14-75 (mean 29.7)days) were inspected following the standard practice (without freezing preparation), and then with 10 cadavers (freezing group: male 7, female 3, age 41-88 (mean 60...
May 2017: Legal Medicine
https://www.readbyqxmd.com/read/28549386/newly-developed-dilute-russell-s-viper-venom-reagents-for-lupus-anticoagulant-detection-with-improved-specificity
#10
G W Moore, M Peyrafitte, C Dunois, J Amiral
Background Dilute Russell's viper venom time (dRVVT) is indispensible in lupus anticoagulant (LA) detection yet commercial reagents from different suppliers perform variably, no gold standard assays exist and therapeutic anticoagulation interference is problematic. Objective The objective of this study was to compare a new formulation dRVVT with two currently available dRVVTs. Materials and methods Life Diagnostics (LD) dRVVT and Stago PTT-LA were routinely used for lupus anticoagulant detection, plus Taipan snake venom time/ecarin time (TSVT/ET) for patients on warfarin or rivaroxaban...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28549340/a-critical-assessment-of-the-in-vitro-measurement-of-cortical-bone-stiffness-with-ultrasound
#11
L Peralta, X Cai, P Laugier, Q Grimal
Elasticity assessment based on bulk wave velocity (BWV) measurements is the most popular technique to characterize the anisotropic stiffness tensor in cortical bone. Typically, a cuboid bone specimen is cut with its sides along the different anatomical directions. Then, the velocity of shear and longitudinal waves propagating along different directions are assessed, from which stiffness coefficients are calculated. Despite the importance of obtaining accurate elasticity values for bone research, there is no generally accepted protocol to measure BWV and the precision of the technique has been seldom investigated...
May 19, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28549187/generalized-joint-hypermobility-a-timely-population-study-and-proposal-for-beighton-cut-offs-beighton-cut-offs-for-generalized-joint-hypermobility
#12
https://www.readbyqxmd.com/read/28549047/health-related-quality-of-life-and-sleep-disorders-in-patients-with-a-urostomy-is-there-a-relationship
#13
Chie Furukawa, Ikuharu Morioka
PURPOSE: The purpose of this study was to evaluate the relationship between health-related quality of life (HRQOL) and sleep disorders in persons living with a urostomy. DESIGN: A cross-sectional descriptive study. SUBJECTS AND SETTINGS: Eighty-six adults with a urostomy who were cared for in a stoma outpatient clinic of a hospital in Osaka, Japan, for at least 1 month before data collection, and who were attending support group meetings comprised the sample...
May 25, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28548947/evaluation-of-cumulative-prognostic-score-based-on-pretreatment-plasma-fibrinogen-and-serum-albumin-levels-in-patients-with-newly-diagnosed-high-grade-gliomas
#14
Zhen-Qiang He, Hao Duan, Chao Ke, Xiang-Heng Zhang, Cheng-Cheng Guo, Fuad Al-Nahari, Ji Zhang, Zheng-He Chen, Yin-Sheng Chen, Zhi-Gang Liu, Jian Wang, Zhong-Ping Chen, Xiao-Bing Jiang, Yong-Gao Mou
This retrospective study was designed to determine the prognostic value of a cumulative score (FA score) based on pretreatment plasma fibrinogen and serum albumin levels for 326 patients newly diagnosed high-grade glioma (HGG). Receiver operating characteristic (ROC) curve analysis was performed to determine the optimal cut-off values. Univariate and multivariate analysis were performed to evaluate the independent prognostic value of the FA scores associated with overall survival (OS) and progression-free survival (PFS)...
May 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/28548557/further-examination-of-embedded-performance-validity-indicators-for-the-conners-continuous-performance-test-and-brief-test-of-attention-in-a-large-outpatient-clinical-sample
#15
Michael J Sharland, Stephen C Waring, Brian P Johnson, Allise M Taran, Travis A Rusin, Andrew M Pattock, Jeanette A Palcher
OBJECTIVE: Assessing test performance validity is a standard clinical practice and although studies have examined the utility of cognitive/memory measures, few have examined attention measures as indicators of performance validity beyond the Reliable Digit Span. The current study further investigates the classification probability of embedded Performance Validity Tests (PVTs) within the Brief Test of Attention (BTA) and the Conners' Continuous Performance Test (CPT-II), in a large clinical sample...
May 26, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28548310/diagnostic-and-prognostic-values-of-club-cell-protein-16-cc16-in-critical-care-patients-with-acute-respiratory-distress-syndrome
#16
Jinle Lin, Wenwu Zhang, Lijun Wang, Fang Tian
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a critical condition characterized by bilateral pulmonary infiltrates and severe hypoxemia. This study aimed to evaluate the diagnostic and prognostic values of Club cell protein 16 (CC16) in critical care patients with ARDS. METHODS: In this retrospective observational study, 83 patients with ARDS and 129 non-ARDS patients on ICU admission were enrolled. The differences in serum CC16 and other laboratory indicators between two groups were analyzed...
May 26, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28548309/tau-%C3%AE-synuclein-ratio-and-inflammatory-proteins-in-parkinson-s-disease-an-exploratory-study
#17
Manuel Delgado-Alvarado, Belén Gago, Ana Gorostidi, Haritz Jiménez-Urbieta, Rosalía Dacosta-Aguayo, Irene Navalpotro-Gómez, Javier Ruiz-Martínez, Alberto Bergareche, José F Martí-Massó, Pablo Martínez-Lage, Andrea Izagirre, María C Rodríguez-Oroz
BACKGROUND: No CSF or plasma biomarker has been validated for diagnosis or progression of PD. OBJECTIVES: To assess whether the CSF and plasma levels of proteins associated with PD neuropathological inclusions and with neuroinflammation might have value in the diagnosis of PD or in relation to disease severity. METHODS: CSF levels of α-synuclein, amyloid-ß1-42, total tau, and threonine-181 phosphorylated tau, as well as CSF and plasma levels of cytokines (interleukin-1ß, interleukin-2, interleukin, interferon-γ, and tumor necrosis factor α) were studied in 40 PD patients and 40 healthy controls...
May 26, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28548308/validation-of-a-french-version-of-the-sleep-condition-indicator-a-clinical-screening-tool-for-insomnia-disorder-according-to-dsm-5-criteria
#18
Sophie Bayard, Cindy Lebrun, Khaalid Hassan Maudarbocus, Vanessa Schellaert, Alicia Joffre, Esther Ferrante, Marie Le Louedec, Alice Cournoulat, Marie-Christine Gely-Nargeot, Annemarie I Luik
Insomnia disorder is frequent in the population, yet there is no French screening instrument available that is based on the updated DSM-5 criteria. We evaluated the validity and reliability of the French version of an insomnia screening instrument based on DSM-5 criteria, the Sleep Condition Indicator, in a population-based sample of adults. A total of 366 community-dwelling participants completed a face-to-face clinical interview to determine insomnia disorder against DSM-5 criteria and several questionnaires including the French Sleep Condition Indicator version...
May 26, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28547982/clinicopathological-study-of-5-cases-of-renal-cell-carcinoma-with-t-6-11-p21-q12
#19
Naoto Kuroda, Kenji Yorita, Naomi Sasaki, Akira Ishihara, Keiko Matsuura, Tsutomu Daa, Shintaro Mori, Aya Sasaki, Shuji Mikami, Kazuto Shigematsu, Yoji Nagashima
Renal cell carcinoma (RCC) with t(6;11)(p21;q12) has been incorporated into the recent WHO classification. We performed a clinicopathological study of 5 cases with such a tumor. The patients consisted of 4 males and 1 female. The age of patients ranged from 17 to 57 years with a mean age of 38.6 years. Tumor sizes ranged from 2.8 to 11 cm with a mean value of 6.5 cm. Despite immunotherapy and molecular-targeted therapy, one patient died of the disease 28 months after the surgery. Grossly, the cut surface of this tumor showed grayish white color in at least the focal area of all tumors...
2017: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
https://www.readbyqxmd.com/read/28547928/application-of-endobronchial-ultrasonography-in-laparoscopic-liver-segmentectomy-in-an-animal-model
#20
Tomoyuki Abe, Tsuyoshi Kobayashi, Seiichi Shimizu, Michinori Hamaoka, Hiroshi Iwako, Masakazu Hashimoto, Yoshihiro Mikuriya, Shintaro Kuroda, Hirotaka Tashiro, Hideki Ohdan
INTRODUCTION: This study investigated whether laparoscopic ultrasound-guided segment staining and real-time ultrasound-guided hepatectomy, with endobronchial ultrasonography equipped with a guide sheath, would be useful for laparoscopic liver segmentectomy in a porcine model. MATERIAL AND SURGICAL TECHNIQUE: The abdominal cavity (in two pigs) was reached via a 12-mm umbilical trocar. An artificial tumor was created by radiofrequency ablation within the intended resection area...
May 2017: Asian Journal of Endoscopic Surgery
keyword
keyword
120178
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"