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https://www.readbyqxmd.com/read/28738666/influence-of-kitesurf-equipment-on-injury-rates
#1
Sebastian F Baumbach, Tanja Stawinski, Daniel Schmitz, Carsten Schoeneberg, Marcus Jäger, Christian Wedemeyer, Max D Kauther
BACKGROUND: Various injuries in kitesurfing (KS) have been reported so far. The aim of this study was to validate the effect of different kite designs and safety equipment on the injury rate compared to older studies. METHODS: A retrospective epidemiological study based on an anonymous face-to-face survey was conducted amongst active kitesurfers. The questionnaire consisted of 66 questions focusing on the equipment used, injury rates, overuse injuries and gender differences...
July 24, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28738644/biosensor-for-the-characterisation-of-hmao-b-inhibitors-and-the-quantification-of-selegiline
#2
Maximilian Aigner, Patricia Preissegger, Kurt Kalcher, Eda Mehmeti, Peter Macheroux, Dale Edmondson, Astrid Ortner
A novel human monoamine oxidase B (hMAO B) based biosensor for inhibitory measurements was developed. It allows both the characterisation of the type of enzyme inhibition and the sensitive and simple determination of inhibitors like selegiline hydrochloride. The sensor consists of a screen printed carbon working electrode modified with 20% manganese dioxide (MnO2) and the enzyme hMAO B, which was immobilised on the electrode via a dialysis membrane (regenerated cellulose, molecular weight cut-off 14000). Inhibition of hMAO B is evaluated by adding different concentrations of the inhibitor selegiline hydrochloride to the enzyme and applying a defined amount of the hMAO B substrate phenylethylamine (PEA)...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28738443/urethral-injection-therapy-for-urinary-incontinence-in-women
#3
REVIEW
Vivienne Kirchin, Tobias Page, Phil E Keegan, Kofi Om Atiemo, June D Cody, Samuel McClinton, Patricia Aluko
BACKGROUND: Urinary incontinence imposes a significant health and economic burden to society. Periurethral or transurethral injection of bulking agents is a minimally invasive surgical procedure used as one the surgical treatments of stress urinary incontinence (SUI) in adult women. OBJECTIVES: To assess the effects of periurethral or transurethral injection therapy on the cure or improvement of urinary incontinence in women. SEARCH METHODS: We searched the Cochrane Incontinence Group Specialised Trials Register (searched 8 November 2010) and the reference lists of relevant articles...
July 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28738370/drug-level-monitoring-on-admission-for-presurgical-epilepsy-evaluation
#4
Irina Constantinescu, Christian M Korff, Serge Vulliemoz, Fabienne Picard, Margitta Seeck
OBJECTIVE: Evaluation for surgical treatment is offered to patients who do not respond to antiepileptic drugs. Pseudo-pharmacoresistance (PPR) has been described in the context of impaired compliance, incorrect diagnosis of epilepsy or pharmacological interference resulting in too low blood levels. We were interested to determine the frequency and causes of PPR in patients admitted for presurgical evaluation. METHODS: We reviewed 553 drug levels in 199 patients and analyzed the relative frequency of drugs below reference range (10 and 20% below the range)...
July 24, 2017: European Neurology
https://www.readbyqxmd.com/read/28738294/oral-mucosa-dose-parameters-predicting-grade-%C3%A2-3-acute-toxicity-in-locally-advanced-nasopharyngeal-carcinoma-patients-treated-with-concurrent-intensity-modulated-radiation-therapy-and-chemotherapy-an-independent-validation-study-comparing-oral-cavity-versus
#5
Kaixin Li, Ling Yang, Qiang-Ying Hu, Xiao-Zhong Chen, Ming Chen, Yuanyuan Chen
PURPOSE: To determine whether volumes based on the contours of the mucosal surface instead of the oral cavity can be used to predict grade ≥3 acute oral mucosa toxicity in patients with locally advanced nasopharyngeal carcinoma (LANPC) treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy. METHODS AND MATERIALS: A standardized method for the oral cavity (oral cavity contours, OCC) and a novel method for the mucosal surface (mucosal surface contours, MSC) were developed for the oral mucosa and prospectively applied to the radiation treatment plans of 92 patients treated with concurrent IMRT and chemotherapy for LANPC...
July 21, 2017: Translational Oncology
https://www.readbyqxmd.com/read/28738292/u-shaped-relationship-between-depression-and-body-mass-index-in-the-korean-adults
#6
J-H Lee, S K Park, J-H Ryoo, C-M Oh, J-M Choi, R S McIntyre, R B Mansur, H Kim, S Hales, J Y Jung
BACKGROUND: Although a number of studies have examined the relationship between depression and obesity, it is still insufficient to establish the specific pattern of relationship between depression and body mass index (BMI) categories. Thus, this study was aimed to investigate the relationship between depression and BMI categories. METHODS: A cross-sectional study was conducted for a cohort of 159,390 Korean based on Kangbuk Samsung Health Study (KSHS). Study participants were classified into 5 groups by Asian-specific cut-off of BMI (18...
June 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28738258/open-label-multicentre-randomised-phase-ii-study-of-the-epssg-and-the-itcc-evaluating-the-addition-of-bevacizumab-to-chemotherapy-in-childhood-and-adolescent-patients-with-metastatic-soft-tissue-sarcoma-the-bernie-study
#7
Julia C Chisholm, Johannes H M Merks, Michela Casanova, Gianni Bisogno, Daniel Orbach, Jean-Claude Gentet, Anne-Sophie Thomassin-Defachelles, Pascal Chastagner, Stephen Lowis, Milind Ronghe, Kieran McHugh, Rick R van Rijn, Magalie Hilton, Jeanette Bachir, Sabine Fürst-Recktenwald, Birgit Geoerger, Odile Oberlin
PURPOSE: We evaluated the role of bevacizumab as part of the multi-modality treatment of children and adolescents with metastatic rhabdomyosarcoma (RMS) or non-rhabdomyosarcoma soft tissue sarcoma (NRSTS). PATIENTS AND METHODS: Eligible patients aged ≥6 months to <18 years were randomised to receive induction chemotherapy (four cycles of IVADo + five cycles of IVA, ±bevacizumab), surgery and/or radiotherapy, followed by maintenance chemotherapy (12 cycles of low-dose cyclophosphamide + vinorelbine, ±bevacizumab)...
July 21, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28738231/sliding-strip-microfluidic-device-enables-elisa-on-paper
#8
Mohit S Verma, Maria-Nefeli Tsaloglou, Tyler Sisley, Dionysios Christodouleas, Austin Chen, Jonathan Milette, George M Whitesides
This article describes a 3D microfluidic paper-based analytical device that can be used to conduct an enzyme-linked immunosorbent assay (ELISA). The device comprises two parts: a sliding strip (which contains the active sensing area) and a structure surrounding the sliding strip (which holds stored reagents-buffers, antibodies, and enzymatic substrate-and distributes fluid). Running an ELISA involves adding sample (e.g. blood) and water, moving the sliding strip at scheduled times, and analyzing the resulting color in the sensing area visually or using a flatbed scanner...
July 19, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28738224/meat-from-cattle-slaughtered-without-stunning-sold-in-the-conventional-market-without-appropriate-labelling-a-case-study-in-italy
#9
Priscilla D'amico, Nicolò Vitelli, Beniamino Cenci Goga, Daniele Nucera, Francesca Pedonese, Alessandra Guidi, Andrea Armani
In the European Union, slaughter without stunning is allowed for religious slaughter to obtain halal and kosher meat. Especially in the case of Jewish slaughtering, cuts which are not deemed as kosher are sold to regular market without any specific labelling. This survey, conducted in Tuscany in 2016, aimed to quantify the carcasses rejected in relation to the type of religious slaughter. 656 bovines were slaughtered without stunning: 538 (82%) for halal and 118 (18%) for kosher. All carcasses slaughtered by the Islamic procedure (dhabiha) were considered halal, while 77...
July 18, 2017: Meat Science
https://www.readbyqxmd.com/read/28738212/the-pattern-of-self-harm-in-fars-province-in-south-iran-a-population-based-study
#10
Saeid Gholamzadeh, Mozhghan Zahmatkeshan, Mohammad Zarenezhad, Elaheh Ghaffari, Sanaz Hoseni
Non-suicidal self-harm includes cutting, scratching, burning and minor overdosing. There have been few studies that have examined the rate and pattern of self-harm among different individuals of the society. We performed a population-based study to determine different aspects of non-suicidal self-harm in cases referred to legal medicine organization of Fars Province and south Iran. In a population-based longitudinal survey, we applied data from cases referred to legal medicine organization of Fars province...
July 5, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28738164/the-risk-stratification-in-patients-with-heart-failure-the-value-of-considering-both-global-longitudinal-left-ventricular-strain-and-mechanical-dispersion
#11
Cristian Mornoş, Danina M Muntean, Aniko Mornos, Simina Crisan, Lucian Petrescu, Adina Ionac, Raluca Sosdean, Dragos Cozma
In previous studies mechanical dispersion (MD) predicted ventricular arrhythmias independently of left ventricular ejection fraction (LVEF). Moreover the combination of MD and global longitudinal strain (GLS) increased the prediction of arrhythmic events. We investigated the prognostic value of a new 2D-strain index, GLS/MD, in patients with heart failure (HF). We analysed 340 consecutive HF outpatients in sinus rhythm. Echocardiography was performed at 1.6±0.4 months after hospital discharge. The end point included sudden cardiac death, ventricular fibrillation and sustained ventricular tachycardia (SCD/VA)...
July 24, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28738096/the-placebo-effect-and-its-clinical-associations-in-gambling-disorder
#12
Jon E Grant, Samuel R Chamberlain
BACKGROUND: Although gambling disorder is prevalent and functionally impairing, no FDA-approved medications exist for its treatment. The ability of clinical trials to detect the benefits of active treatment has been hindered by an unusually high placebo response. Virtually nothing is known about baseline clinical characteristics that might predict placebo response in those with gambling disorder. METHODS: Participants (N = 152) assigned to placebo were pooled from multiple double-blind trials of gambling disorder...
August 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/28737887/enhanced-triboelectric-nanogenerators-based-on-mos2-monolayer-nanocomposites-acting-as-electron-acceptor-layers
#13
Chaoxing Wu, Tae Whan Kim, Jae Hyeon Park, Haoqun An, Jiajia Shao, Xiangyu Chen, Zhong Lin Wang
As one of their major goals, researchers attempting to harvest mechanical energy efficiently have continuously sought ways to integrate mature technologies with cutting-edge designs to enhance the performances of triboelectric nanogenerators (TENGs). In this research, we introduced monolayer molybdenum-disulfide (MoS2) into the friction layer of a TENG as the triboelectric electron-acceptor layer in an attempt to dramatically enhance its output performance. As a proof of the concept, we fabricated a vertical contact-separation mode TENG containing monolayer MoS2 as an electron-acceptor layer and found that the TENG exhibited a peak power density as large as 25...
July 24, 2017: ACS Nano
https://www.readbyqxmd.com/read/28737302/an-exploratory-service-based-study-of-deliberate-self-harm-dsh-in-ireland-a-hidden-population
#14
P Quinn, P Surgenor, S McGilloway
The aim of this study was to investigate the nature and extent of deliberate self-harm (DSH) amongst those attending national crisis centres in Ireland, and to assess clients' views of the service. A secondary analysis was undertaken of a large data set of clients presenting with DSH (n=823). Clients were predominantly female, under 25 and with self-cutting widely reported (73%). DSH co-occurred with suicidal ideation (SI) (42%) and/or a suicide attempt (SA) (35%). Males were significantly more likely to present with more severe problems, and to use more dramatic methods of DSH; more severe presenting issues were also significantly associated with a history of having friends who engage in DSH...
May 10, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/28737011/a-distinctive-patchy-osteomalacia-characterises-phospho1-deficient-mice
#15
Alan Boyde, Katherine A Staines, Behzad Javaheri, Jose Luis Millan, Andrew A Pitsillides, Colin Farquharson
The phosphatase PHOSPHO1 is involved in the initiation of biomineralisation. Bones in Phospho1 knockout (KO) mice show histological osteomalacia with frequent bowing of long bones and spontaneous fractures: they contain less mineral, with smaller mineral crystals. However, the consequences of Phospho1 ablation on the microscale structure of bone are not yet fully elucidated. Tibias and femurs obtained from wild-type and Phospho1 null (KO) mice (25-32 weeks old) were embedded in PMMA, cut and polished to produce near longitudinal sections...
August 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28736928/mean-platelet-volume-predicts-prognosis-in-patients-with-diffuse-large-b-cell-lymphoma
#16
Shujuan Zhou, Yongyong Ma, Yifen Shi, Liyuan Tang, Zhouyi Zheng, Fang Fang, Jianhua Feng, Yu Zhang, Lan Sun, Yi Chen, Bin Liang, Songfu Jiang, Zhijian Shen, Kang Yu, Siqian Wang
To determine the prognostic value of baseline mean platelet volume (MPV) in diffuse large B-cell lymphoma (DLBCL) patients. We retrospectively analyzed 161 DLBCL patients who received R-CHOP chemotherapy. The associations between MPV and clinicopathological factors were assessed. A low MPV (MPV ≤ 9.1 fl, cut-off was calculated by receiver operating characteristics) was associated with any other clinicopathological factors. Patients with MPV ≤ 9.1 fl experienced a shorter progression-free survival (PFS) (2-year PFS rate, 60...
July 23, 2017: Hematological Oncology
https://www.readbyqxmd.com/read/28736341/tfos-dews-ii-iatrogenic-report
#17
REVIEW
José Alvaro P Gomes, Dimitri T Azar, Christophe Baudouin, Nathan Efron, Masatoshi Hirayama, Jutta Horwath-Winter, Terry Kim, Jodhbir S Mehta, Elisabeth M Messmer, Jay S Pepose, Virender S Sangwan, Alan L Weiner, Steven E Wilson, James S Wolffsohn
Dry eye can be caused by a variety of iatrogenic interventions. The increasing number of patients looking for eye care or cosmetic procedures involving the eyes, together with a better understanding of the pathophysiological mechanisms of dry eye disease (DED), have led to the need of a specific report about iatrogenic dry eye within the TFOS DEWS II. Topical medications can cause DED due to their allergic, toxic and immuno-inflammatory effects on the ocular surface. Preservatives, such as benzalkonium chloride, may further aggravate DED...
May 5, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28736229/survival-of-patients-with-cutaneous-squamous-cell-carcinoma-results-of-a-prospective-cohort-study
#18
Thomas K Eigentler, Ulrike Leiter, Hans-Martin Häfner, Claus Garbe, Martin Röcken, Helmut Breuninger
Cutaneous squamous cell carcinoma (cSCC) is an increasing health burden in Caucasian populations. We prospectively assessed risk factors for tumour-specific and overall survival in 1434 patients who underwent surgery for cSCC between Jan 24, 2005, and May 29, 2015. A total of 2149 invasive cSCCs were analysed. Univariate and multivariate survival analyses included tumour thickness, horizontal size, body site, histological differentiation, desmoplastic growth, history of multiple cSCC, and immunosuppression...
July 20, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28736098/posterior-canal-wall-reposition-for-management-of-cholesteatoma-technique-and-results
#19
Mohammad Kamal Mobashir, Waleed M Basha, Abd ElRaof Said Mohamed, Mohammed Elsayed Elmaghawry
OBJECTIVE: The main goal of surgery in acquired middle ear cholesteatomas is the complete eradication of the disease with an ear free of discharge. This can be performed either by open or closed techniques with their benefits and drawbacks. We present the technique of reposition of the posterior canal wall for the management of cholesteatoma cases and its results and outcome. PATIENTS AND METHODS: This study included 31 patients with primary acquired middle ear cholesteatoma...
July 20, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28736054/low-sensitivity-of-anion-gap-to-detect-clinically-significant-lactic-acidosis-in-the-emergency-department
#20
Q Xu, S HowlettClyne, A Fuezery, G S Cembrowski
INTRODUCTION: Lactic acidosis represents the pathologic accumulation of lactate and hydrogen ions. It is important to efficiently diagnose lactic acidosis as delayed treatment will lead to poor patient outcomes. As plasma lactate levels may not be rapidly available, some physicians may use elevated anion gaps to test for the need to measure lactate. All Edmonton metropolitan hospitals have Radiometer blood gas/electrolyte instruments in the ED or close by. As lactate is measured for each set of electrolytes, we were able to determine the effectiveness of a screening anion gap for lactic acidosis...
July 20, 2017: Clinical Biochemistry
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