keyword
Keywords Guidelines for Hospital-acquir...

Guidelines for Hospital-acquired infection

https://read.qxmd.com/read/38381949/long-acting-injectable-antiretrovirals-for-hiv-treatment-a-multi-site-qualitative-study-of-clinic-level-barriers-to-implementation-in-the-united-states
#21
MULTICENTER STUDY
Tara McCrimmon, Lauren F Collins, Amaya Perez-Brumer, Angela R Bazzi, Victoria A Shaffer, Deanna Kerrigan, Maria L Alcaide, Morgan M Philbin
Long-acting injectable antiretroviral therapy (LAI ART) has the potential to address adherence obstacles associated with daily oral ART, leading to enhanced treatment uptake, adherence, and viral suppression among people living with HIV (PLWH). Yet, its potential may be limited due to ongoing disparities in availability and accessibility. We need a better understanding of the organizational context surrounding the implementation of LAI ART, and to inform its widespread rollout, we conducted 38 in-depth interviews with medical and social service providers who offer HIV care at private and hospital-based clinics across six US cities...
February 2024: AIDS Patient Care and STDs
https://read.qxmd.com/read/38328895/express-compliance-with-guidelines-recommendations-in-the-management-of-patients-with-hospitalized-community-acquired-pneumonia
#22
JOURNAL ARTICLE
Pinar Bakir Ekinci, Emre Kara, Gulcin Telli Dizman, Sefa Metin, Ahmet Cagkan Inkaya, Kutay Demirkan, Lutfi Coplu, Serhat Ünal
Compliance with guidelines in the empirical treatment for community-acquired pneumonia (CAP) is very important to increase treatment success and reduce mortality. This study aimed to determine compliance with guidelines recommendations for CAP and define the role of the clinical pharmacist (CP). Patients diagnosed with CAP were evaluated retrospectively between January 2018 and January 2020 and prospectively between February 2020 and February 2021. Compliance with guidelines was evaluated according to the local, national (Turkish Thoracic Society) and international (American Thoracic Society and Infectious Disease Society of America), European Society of Clinical Microbiology and Infectious Diseases) guidelines...
February 8, 2024: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://read.qxmd.com/read/38298158/development-of-patient-safety-measures-to-identify-inappropriate-diagnosis-of-common-infections
#23
JOURNAL ARTICLE
Andrea T White, Valerie Vaughn, Lindsay A Petty, Tejal N Gandhi, Jennifer K Horowitz, Scott A Flanders, Steven J Bernstein, Timothy Hofer, David Ratz, Elizabeth S McLaughlin, Daniel Nielsen, Tawny Czilok, Jennifer Minock, Ashwin Gupta
BACKGROUND: Inappropriate diagnosis of infections results in antibiotic overuse and may delay diagnosis of underlying conditions. Here, we describe the development and characteristics of two safety measures of inappropriate diagnosis of urinary tract infection (UTI) and community-acquired pneumonia (CAP), the most common inpatient infections on general medicine services. METHODS: Measures were developed from guidelines and literature and adapted based on data from patients hospitalized with UTI and CAP in 49 Michigan hospitals and feedback from end-users, a technical expert panel (TEP), and a patient focus group...
January 31, 2024: Clinical Infectious Diseases
https://read.qxmd.com/read/38279954/efficacy-of-palivizumab-immunoprophylaxis-for-reducing-severe-rsv-outcomes-in-children-with-immunodeficiencies-a-systematic-review
#24
JOURNAL ARTICLE
Frederic Reicherz, Bahaa Abu-Raya, Omolabake Akinseye, Shahrad Rod Rassekh, Matthew O Wiens, Pascal M Lavoie
BACKGROUND: Palivizumab is recommended for prevention of severe respiratory syncytial virus (RSV) disease in immunocompromised children, despite a lack of strong supporting evidence. The recent approval of substitute RSV-neutralizing monoclonal antibodies against RSV, offers an opportunity to synthesize the most current evidence supporting the palivizumab standard of care. OBJECTIVE: To evaluate the efficacy of palivizumab in preventing acute respiratory tract infection- or RSV-related hospitalization, or mortality in immunocompromised children...
February 26, 2024: Journal of the Pediatric Infectious Diseases Society
https://read.qxmd.com/read/38256476/infectious-complications-of-pulmonary-sarcoidosis
#25
REVIEW
Dominique Valeyre, Jean-François Bernaudin, Michel Brauner, Hilario Nunes, Florence Jeny
In this review, the infectious complications observed in sarcoidosis are considered from a practical point of view to help the clinician not to overlook them in a difficult context, as pulmonary sarcoidosis makes the recognition of superinfections more difficult. An increased incidence of community-acquired pneumonia and of opportunistic pneumonia has been reported, especially in immunosuppressed patients. Pulmonary destructive lesions of advanced sarcoidosis increase the incidence of chronic pulmonary aspergillosis and infection by other agents...
January 7, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38234215/parent-and-clinician-views-on-not-using-antibiotics-for-mild-community-acquired-pneumonia
#26
JOURNAL ARTICLE
Julia E Szymczak, Ashley A Hayes, Patricia Labellarte, Julian Zighelboim, Amandeep Toor, Adam B Becker, Jeffrey S Gerber, Nathan Kuppermann, Todd A Florin
OBJECTIVES: Preschool-aged children with mild community-acquired pneumonia (CAP) routinely receive antibiotics even though most infections are viral. We sought to identify barriers to the implementation of a "no antibiotic" strategy for mild CAP in young children. METHODS: Qualitative study using semistructured interviews conducted in a large pediatric hospital in the United States from January 2021 to July 2021. Parents of young children diagnosed with mild CAP in the previous 3 years and clinicians practicing in outpatient settings (pediatric emergency department, community emergency department, general pediatrics offices) were included...
January 1, 2024: Pediatrics
https://read.qxmd.com/read/38143681/microbial-profile-of-tourniquets-used-in-phlebotomy-at-a-rural-tertiary-care-teaching-hospital
#27
JOURNAL ARTICLE
Arvind Natarajan, Subhashish Das, Nikhil Chaudhary
Background Reusable phlebotomy tourniquets may become contaminated through repeated use on the skin surfaces of multiple patients, the hands of healthcare workers, or various surfaces. Noncompliance with the protocol guidelines for managing tourniquets can contribute to the cross-transmission of microorganisms among patients. This study was conducted to determine the microbial flora and antimicrobial sensitivity pattern of reusable phlebotomy tourniquets. Methodology Tourniquets were randomly sampled across the different areas of the hospital and were transported to the microbiology laboratory for isolation, identification, and antibiotic susceptibility testing of microorganisms using standard microbiological techniques...
November 2023: Curēus
https://read.qxmd.com/read/38141665/burdens-of-infection-control-on-healthcare-workers-a-scoping-review
#28
REVIEW
Rafael Ungar, Rachel Gur-Arie, George S Heriot, Euzebiusz Jamrozik
INTRODUCTION: Hospital acquired injections (HAI) pose a significant risk to patients and are a major focus of infection prevention and control policies (IPC). One under-recognised reason for the generally poor compliance with IPC is that it is burdensome for healthcare workers (HCW) to comply with these policies. AIMS: This paper seeks to identify the burdens of IPC for HCW. METHODS: We searched PubMed and CINAHL for literature since 2000 in English regarding compliance with IPC and the burdens associated with compliance...
December 21, 2023: Journal of Hospital Infection
https://read.qxmd.com/read/38136712/antibiotic-guideline-adherence-at-the-emergency-department-a-descriptive-study-from-a-country-with-a-restrictive-antibiotic-policy
#29
JOURNAL ARTICLE
Mariana B Cartuliares, Sara N Søgaard, Flemming S Rosenvinge, Christian B Mogensen, Mathias Amdi Hertz, Helene Skjøt-Arkil
BACKGROUND: Denmark has a low level of antimicrobial resistance (AMR). Patients hospitalized with suspected infection often present with unspecific symptoms. This challenges the physician between using narrow-spectrum antibiotics in accordance with guidelines or broad-spectrum antibiotics to compensate for diagnostic uncertainty. The aim of this study was to investigate adherence to a restrictive antibiotic guideline for the most common infection in emergency departments (EDs), namely community-acquired pneumonia (CAP)...
November 29, 2023: Antibiotics
https://read.qxmd.com/read/38130702/a-national-antimicrobial-guide-with-local-customizable-versions-how-is-it-used-a-two-year-analysis
#30
JOURNAL ARTICLE
Emelie C Schuts, Anders Boyd, Stephanie Natsch, Arjen Veenman, Jan M Prins
OBJECTIVES: Guideline adherence is one of the most important objectives for antibiotic stewardship. The Dutch Working Party on Antibiotic Policy (SWAB) developed an online national guide (SWAB-ID) in 2006. Every Dutch hospital is offered the opportunity to customize the national version to their local context and distribute it through an independent website. We studied user data to see how often the guidelines on therapy, prophylaxis and medication are used. METHODS: Data on usage between 19 June 2020 and 30 June 2022 were extracted through Google Analytics for the national site and the 53 hospitals using a customized version of the national guide...
December 2023: JAC-antimicrobial resistance
https://read.qxmd.com/read/38125533/predictors-of-hospital-mortality-and-multidrug-resistant-pathogens-in-hospitalized-pneumonia-patients-residing-in-the-community
#31
JOURNAL ARTICLE
Tomohiko Ukai, Takaya Maruyama, Shinichi Tomioka, Takumi Fukui, Shinya Matsuda, Kiyohide Fushimi, Hiroyasu Iso
BACKGROUND AND OBJECTIVE: The 2019 ATS/ADSA guidelines for adult community-acquired pneumonia (CAP) eliminated healthcare-associated pneumonia (HCAP) and considered it to be a form of CAP. This concept, however, was based on studies with relatively small sample sizes. METHODS: We investigated the risk factors of 30-day mortality, and methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa infections in patients with pneumonia coming from the community using the Diagnosis Procedure Combination database, a nationwide discharge database of acute care hospitals...
December 2023: Heliyon
https://read.qxmd.com/read/38113098/predisposing-factors-of-nosocomial-infections-in-hospitalized-patients-in-the-united-kingdom-systematic-review
#32
REVIEW
Sharon Shivuli Isigi, Ali Davod Parsa, Ibrahim Alasqah, Ilias Mahmud, Russell Kabir
BACKGROUND: Nosocomial infections are infections incubating or not present at the time of admission to a hospital and manifest 48 hours after hospital admission. The specific factors contributing to the risk of infection during hospitalization remain unclear, particularly for the hospitalized population of the United Kingdom. OBJECTIVE: The aim of this systematic literature review was to explore the risk factors of nosocomial infections in hospitalized adult patients in the United Kingdom...
December 19, 2023: JMIR Public Health and Surveillance
https://read.qxmd.com/read/38112966/clinical-characteristics-and-antimicrobial-susceptibility-of-fusobacterium-species-isolated-over-10%C3%A2-years-at-a-japanese-university-hospital
#33
JOURNAL ARTICLE
Nobuaki Mori, Akiko Nakamura, Jun Hirai, Nobuhiro Asai, Yuichi Shibata, Mina Takayama, Yuzuka Kawamoto, Narimi Miyazaki, Daisuke Sakanashi, Tomoko Ohno, Atsuko Yamada, Hiroyuki Suematsu, Isao Koita, Sumie Chida, Toshiaki Ohta, Hiroshige Mikamo
PURPOSE: Anaerobic bacteria, existing on human skin and mucous membranes, can cause severe infections with complications or mortality. We examined the clinical characteristics of patients infected with Fusobacterium spp. and assessed their antibiotic susceptibility. METHODS: Clinical data were collated from patients diagnosed with Fusobacterium infections in a Japanese university hospital between 2014 and 2023. Antibiotic susceptibility tests were conducted following the Clinical and Laboratory Standards Institute guidelines...
December 19, 2023: European Journal of Clinical Microbiology & Infectious Diseases
https://read.qxmd.com/read/38107218/audit-of-tracheostomy-care-practices-in-a-nigerian-tertiary-neurosurgical-intensive-care-unit-according-to-published-guidelines
#34
JOURNAL ARTICLE
Kenechukwu K Igbokwe, Reginald N Ononye, Daniel E Onobun, Ugochukwu C Ugwuanyi
INTRODUCTION: Chest infections are a frequently encountered problem in patients admitted to the intensive care unit (ICU), more so in tracheostomised patients. This study aimed to audit the tracheostomy care practices in patients with neurosurgical pathologies in the ICU of Wellington Clinics Abuja, a tertiary neurosurgical hospital in Nigeria. METHODS: We conducted a closed-loop audit with mixed methods involving analysis of 24 patients who had tracheostomy within the first two weeks of neurosurgical pathology at a tertiary neurosurgical hospital and semi-structured interviews to determine tracheostomy care practices among the primary caregivers - nurses, intensivists, and doctors...
December 2023: Curēus
https://read.qxmd.com/read/38103753/efficacy-of-clofazimine-containing-regimens-for-treatment-of-mycobacterium-avium-complex-pulmonary-disease-in-patients-unsuitable-for-standard-treatment-regimen
#35
JOURNAL ARTICLE
Shengjuan Bao, Suting Chen, Jifang Zheng, Junke Ma, Jiali Yang, Hairong Huang, Hongfei Duan
OBJECTIVES: Patients with Mycobacterium avium complex-pulmonary disease (MAC-PD) can exhibit contraindications in applying the recommended treatment regimens by the guidelines. Clofazimine (CFZ) is considered a promising drug for MAC-PD treatment and is frequently included in alternative regimens; however, its efficacy remains unclear. METHODS: MAC-PD patients, unsuitable for standard regimens, were enrolled continuously in a prospective study at Beijing Chest Hospital...
December 14, 2023: International Journal of Antimicrobial Agents
https://read.qxmd.com/read/38072378/association-of-pharmacologic-thromboprophylaxis-with-clinically-relevant-bleeding-and-hospital-acquired-anemia-in-medical-inpatients-the-risk-stratification-for-hospital-acquired-venous-thromboembolism-in-medical-patients-study
#36
JOURNAL ARTICLE
Damien Choffat, Jean-Benoît Rossel, Drahomir Aujesky, Peter Vollenweider, Christine Baumgartner, Marie Méan
BACKGROUND: Pharmacologic thromboprophylaxis (pTPX) might exacerbate the risk of clinically relevant bleeding (CRB) and hospital-acquired anemia (HAA) in older multimorbid inpatients. OBJECTIVES: We aimed to evaluate the association of pTPX use with CRB and HAA. METHODS: We used data from a prospective cohort study conducted in 3 Swiss university hospitals. Adult patients admitted to internal medicine wards with no therapeutic anticoagulation were included...
December 9, 2023: Journal of Thrombosis and Haemostasis: JTH
https://read.qxmd.com/read/38046478/comparison-between-pantoprazole-intermittent-dosing-and-continuous-infusion-in-suspected-upper-gastrointestinal-bleeding-prior-to-endoscopy-impact-of-a-pharmacist-driven-protocol-to-reduce-utilization-of-pantoprazole-continuous-infusion
#37
JOURNAL ARTICLE
Ivan A Hernandez, Jason Morell, Lauren Mulcahy, Daniela Luzardo
BACKGROUND: Current practice for patients with suspected or confirmed upper gastrointestinal bleeding (GIB) is to utilize a proton pump inhibitor (PPI) bolus followed by a continuous infusion for 72 hours. Literature has shown similar outcomes with intermittent bolus dosing compared to continuous infusion. Substitution would lead to reduced costs and utilization of resources. METHODS: This was a retrospective case-control study conducted via chart review. Utilizing electronic healthcare record reports, patients in the control arm were screened for inclusion if they received a pantoprazole continuous infusion from December 1, 2020, to March 31, 2021...
October 2023: Curēus
https://read.qxmd.com/read/38028917/derivation-and-external-validation-of-a-prediction-model-for-pneumococcal-urinary-antigen-test-positivity-in-patients-with-community-acquired-pneumonia
#38
JOURNAL ARTICLE
Priscilla Kim, Michael B Rothberg, Amy S Nowacki, Pei-Chun Yu, David Gugliotti, Abhishek Deshpande
OBJECTIVE: Derive and externally validate a prediction model for pneumococcal urinary antigen test (pUAT) positivity. METHODS: Retrospective cohort study of adults admitted with community-acquired pneumonia (CAP) to 177 U.S. hospitals in the Premier Database (derivation and internal validation samples) or 12 Cleveland Clinic hospitals (external validation sample). We utilized multivariable logistic regression to predict pUAT positivity in the derivation dataset, followed by model performance evaluation in both validation datasets...
2023: Antimicrob Steward Healthc Epidemiol
https://read.qxmd.com/read/37983850/profile-of-helicobacter-pylori-infections-among-children-in-the-south-island-of-new-zealand-2010-2021
#39
JOURNAL ARTICLE
Angharad Vernon-Roberts, Malshi Premaratne, Raewyn Wright, Jacqueline I Keenan, Andrew S Day
BACKGROUND: Helicobacter pylori is a gram-negative gut bacterium most often acquired during childhood. International guidelines state that children with suspected H. pylori infection should be referred to a gastroenterologist for investigation via gastroscopy and biopsy. Eradication therapy should be prescribed for children with peptic ulcer disease or following a treatment risk/benefit discussion for those with an incidental gastroscopy finding. Guidelines state that for children a "test-and-treat" approach is not warranted, contrasting recommendations for adults...
November 20, 2023: Helicobacter
https://read.qxmd.com/read/37970711/whs-guidelines-for-the-treatment-of-pressure-ulcers-2023-update
#40
JOURNAL ARTICLE
Lisa J Gould, Jenny Alderden, Rummana Aslam, Adrian Barbul, Kath M Bogie, Mohamed El Masry, Letitia Y Graves, E Foy White-Chu, Amany Ahmed, KerriAnn Boanca, Jessica Brash, Katie R Brooks, Wendy Cockron, Susan M Kennerly, Aaron K Livingston, Jeni Page, Catherine Stephens, Velena West, Tracey L Yap
The major populations at risk for developing pressure ulcers are older adults who have multiple risk factors that increase their vulnerability, people who are critically ill and those with spinal cord injury/disease. The reported prevalence of pressure ulcers in the United States is 2.5 million. However, this estimate is derived from acute care facilities and does not include people who are living at home or in nursing facilities. Despite the implementation of hospital and facility-based preventive measures, the incidence of pressure ulcers has not decreased in decades...
November 16, 2023: Wound Repair and Regeneration
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