keyword
https://read.qxmd.com/read/38530971/thorax-support-vest-to-prevent-sternal-wound-infections-in-cardiac-surgery-patients-a-systematic-review-and-meta-analysis
#1
JOURNAL ARTICLE
Tulio Caldonazo, Michele Dell'Aquila, Gianmarco Cancelli, Lamia Harik, Giovanni Soletti, Johannes Fischer, Hristo Kirov, Mohamed Rahouma, Mudathir Ibrahim, Michelle Demetres, Kevin R An, Leonard Girardi, Torsten Doenst, Mario Gaudino
OBJECTIVES: Midline sternotomy is the main surgical access for cardiac surgeries. The most prominent complication of sternotomy is sternal wound infection (SWI). The use of a thorax support vest (TSV) that limits thorax movement and ensures sternal stability has been suggested to prevent postoperative SWI. We performed a meta-analysis to evaluate differences in clinical outcomes with and without the use of TSV after cardiac surgery in randomized trials. METHODS: The primary outcome was deep SWI (DSWI)...
March 26, 2024: Interdiscip Cardiovasc Thorac Surg
https://read.qxmd.com/read/38530698/ultrasound-guided-radial-artery-puncture-by-nurses-in-emergency-department-a-randomized-controlled-study
#2
JOURNAL ARTICLE
Birdal Güllüpınar, Caner Sağlam, Arif Karagöz, Serhat Koran, Erden Erol Ünlüer
INTRODUCTION: Radial artery puncture has been performed by palpation as a standard method in many emergency departments and intensive care units. Nurses play an important role in the care of patients in various settings. Ultrasonography can be performed and interpreted not only by physicians but also by nurses. This study aimed to evaluate whether emergency nurses would be more successful in radial artery puncture procedure by using ultrasonography instead of palpation. METHODS: This single-center, prospective, randomized controlled study was conducted in the emergency department...
March 26, 2024: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://read.qxmd.com/read/38530540/the-functional-study-of-response-regulator-arlr-mutants-in-staphylococcus-aureus
#3
JOURNAL ARTICLE
Jinhong Zhou, Moath Refat, Yucheng Guo, Jiaxin Zhang, Min Jiao, Wenbo He, Xiaoyu He, Mai A Rabie, Zhenlin Ouyang, Fang Zheng
Staphylococcus aureus is a major cause of hospital-associated infections worldwide. The organism's ability to form biofilms has led to resistance against current treatment options such as beta-lactams, glycopeptides, and daptomycin. The ArlRS two-component system is a crucial regulatory system necessary for S. aureus autolysis, biofilm formation, capsule synthesis, and virulence. This study aims to investigate the role of the arlR deletion mutant in the detection and activation of S. aureus. We created an arlR deleted mutant and complementary strains and characterized their impact on the strains using partial growth measurement...
March 26, 2024: Applied Biochemistry and Biotechnology
https://read.qxmd.com/read/38530494/bacteriuria-in-patients-with-stented-ureters-predictors-of-infection-in-patients-presenting-to-the-hospital-and-when-not-to-treat
#4
JOURNAL ARTICLE
Deepak Batura, Momin Elsweefy, Rhea Chouhan, Paul Bassett, Guduru Gopal Rao
PURPOSE: Patients with ureteric stents have symptoms that overlap with infection symptoms. Thus, clinicians unnecessarily give antibiotics to stented patients with bacteriuria despite guidelines. In stented patients, little is known about risk factors for developing bacteriuria or urosepsis. The objectives were to identify the frequency and risk factors for developing bacteriuria and urosepsis in patients with stents. METHODS: In this retrospective cohort study, we reviewed patients with ureteric stents placed or exchanged over 1 year...
March 26, 2024: World Journal of Urology
https://read.qxmd.com/read/38530465/multidrug-resistant-organism-bloodstream-infection-and-hospital-acquisition-among-inpatients-in-three-tertiary-greek-hospitals-during-the-covid-19-era
#5
JOURNAL ARTICLE
Polyxeni Karakosta, Sophia Vourli, Elisavet Kousouli, Georgios Meletis, Areti Tychala, Christina Louka, Alexandra Vasilakopoulou, Efthymia Protonotariou, Vasiliki Mamali, Olympia Zarkotou, Lemonia Skoura, Spyros Pournaras
From 2019 (pre-COVID-19) to 2022 (COVID-19 years), three tertiary Greek hospitals monitored MDRO bloodstream infection (BSI) and hospital acquisition relying on laboratory data. Surveillance covered carbapenem-resistant Enterobacterales (CRE), Acinetobacter baumannii (CRAB), Pseudomonas aeruginosa (CRPA), vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA), in intensive care units (ICUs) and non-ICUs. Non-ICUs experienced significant increases in CRE, CRAB and VRE during the pandemic...
March 26, 2024: European Journal of Clinical Microbiology & Infectious Diseases
https://read.qxmd.com/read/38530447/association-of-vitamin-d-with-disease-severity-in-infants-with-bronchiolitis
#6
JOURNAL ARTICLE
Jashan Mittal, Nikhil Rajvanshi, Kkomal Suvarna, Prawin Kumar, Jagdish Prasad Goyal
UNLABELLED: Vitamin D's role in immune system regulation and its contribution to host defenses against respiratory infections may have implications for bronchiolitis pathophysiology. This cross-sectional study aimed to determine the association between the clinical severity of bronchiolitis and serum vitamin D levels in infants. Infants aged 1 month to 12 months, diagnosed with bronchiolitis, and healthy controls attending routine immunization were enrolled. Baseline characteristics were recorded, including clinical details, bronchiolitis severity, and course during hospital stay...
March 26, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38529931/acute-kidney-injury-in-children-with-lymphoma
#7
JOURNAL ARTICLE
Hejia Zhang, Yanlong Duan, Xiaoxue Li, Zhi Chen, Xiaorong Liu
OBJECTIVE: To analyze the epidemiology of acute kidney injury (AKI) in children with lymphoma and to assess the incidence, risk profile of AKI, and effects on renal function in children with lymphoma during their first 30 days of hospitalization. MATERIALS AND METHODS: This was a retrospective screen of electronic hospital and laboratory databases to select hospitalized children who were first diagnosed and treated for lymphoma at Beijing Children's Hospital between 2020 and 2021...
March 26, 2024: Clinical Nephrology
https://read.qxmd.com/read/38529781/sink-interventions-in-the-icu-to-reduce-risk-of-infection-or-colonization-with-gram-negative-pathogens-a-systematic-review-of-the-literature
#8
REVIEW
G-B Fucini, C Hackmann, P Gastmeier
BACKGROUND: Healthcare-associated infections (HAIs) are a major problem in intensive care units (ICUs). The hospital water environment is a potential reservoir for Gram-negative bacteria (GNB), and it has been shown that contaminated sinks contribute to the spread of GNB in outbreak and non-outbreak settings. This study aimed to investigate which sink interventions may reduce GNB infection and colonization rates in the ICU. METHODS: A database search (MEDLINE via PubMed, EMBASE via Ovid and ClinicalTrials...
January 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38529780/increased-rates-of-hospital-onset-staphylococcus-aureus-bacteraemia-in-national-health-service-acute-trusts-in-england-between-june-2020-and-march-2021-a-national-surveillance-review
#9
JOURNAL ARTICLE
E Mason, O Nsonwu, J Elmes, D Chudasama, C Pearson, L Hasan, R Hope, S M Gerver
A large increase in hospital-onset and intensive-care-unit-onset Staphylococcus aureus bacteraemia rates in English acute trusts was observed between 2020 and 2021, coinciding with reported increases in coronavirus disease (COVID-19) cases and associated hospitalizations. Many of these S. aureus bacteraemia cases were defined as co-/secondary infections to COVID-19. Over the same period, increases in the percentage of ventilator-associated pneumonia-related bacteraemia were also found. The COVID-19 pandemic appears to have contributed to the increase in hospital-onset S...
January 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38529671/pleural-fluid-characteristics-of-patients-with-covid-19-infection
#10
JOURNAL ARTICLE
Ryan A Denu, Victoria Forth, Majid Shafiq
INTRODUCTION: Pleural effusions are known to occur in many cases of COVID-19. Data on typical characteristics of COVID-19-associated pleural effusions are limited. The goal of this project was to characterize the pleural fluid from patients with COVID-19. METHODS: We retrospectively collected electronic medical record data from adults hospitalized at a large metropolitan hospital system with COVID-19 infection who had a pleural effusion and a thoracentesis performed...
March 2024: Clinical Respiratory Journal
https://read.qxmd.com/read/38529574/covid-19-outcome-and-tobacco-product-use-case-control-and-retrospective-cohort-studies-using-nationwide-samples
#11
JOURNAL ARTICLE
Seo Young Kang, Ye-Jee Kim, Hong-Jun Cho
BACKGROUND: Conflicting evidence exists regarding the association between smoking and the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We investigated the association between combustible cigarette (CC) smoking, noncombustible tobacco product (NCTP) use, and the use of any tobacco product with various coronavirus disease 2019 (COVID-19) outcomes. METHODS: A case-control study was conducted using the Korea Disease Control and Prevention Agency-COVID19-National Health Insurance Service (NHIS) cohort...
March 25, 2024: Journal of Korean Medical Science
https://read.qxmd.com/read/38529068/the-role-of-aggf1-in-the-classification-and-evaluating-prognosis-of-adult-septic-patients-an-observational-study
#12
JOURNAL ARTICLE
Wenqing Ji, Tiantian Wan, Fang Zhang, Shubin Guo, Xue Mei
PURPOSE: Angiogenic factor with G patch and FHA domains 1 (AGGF1) is a crucial angiogenic factor that is involved in a variety of diseases and in the regulation of inflammatory responses. However, its role in sepsis is poorly understood. We have investigated the role of AGGF1 in the classification and prognostic evaluation of adult septic patients in a clinical context. PATIENTS AND METHODS: A total of 126 septic patients who visited the Emergency Department of Beijing Chao-Yang Hospital and 76 non-sepsis patients visiting the Physical Examination Center of Beijing Chao-Yang Hospital were enrolled...
2024: Infection and Drug Resistance
https://read.qxmd.com/read/38529003/carbapenem-resistant-klebsiella-pneumoniae-among-hospitalized-patients-in-cape-town-south-africa-molecular-epidemiology-and-characterization
#13
COMMENT
Gert Marais, Clinton Moodley, Shantelle Claassen-Weitz, Fadheela Patel, Elizabeth Prentice, Hafsah Tootla, Nyasha Nyakutira, Katie Lennard, Kessendri Reddy, Colleen Bamford, Abraham Niehaus, Andrew Whitelaw, Adrian Brink
BACKGROUND: The molecular epidemiology of carbapenem-resistant Enterobacterales in Cape Town remains largely unknown. OBJECTIVES: This study aimed to describe the molecular epidemiology, resistome, virulome and mobilome of carbapenem-resistant Klebsiella pneumoniae (CRKP) within Cape Town to guide therapy, antimicrobial stewardship and infection prevention and control practices. METHODS: Eighty-five CRKP isolates from hospitalized patients underwent WGS as part of a prospective, multicentre, cross-sectional study, conducted between 1 November 2020 and 30 November 2022, across public-sector and private-sector hospitals in Cape Town, South Africa...
April 2024: JAC-antimicrobial resistance
https://read.qxmd.com/read/38528616/clinical-and-economic-burden-of-respiratory-syncytial-virus-in-children-aged-0-5-years-in-italy
#14
JOURNAL ARTICLE
Melania Dovizio, Chiara Veronesi, Fausto Bartolini, Arturo Cavaliere, Stefano Grego, Romina Pagliaro, Cataldo Procacci, Loredana Ubertazzo, Lorenzo Bertizzolo, Barbara Muzii, Salvatore Parisi, Valentina Perrone, Eugenio Baraldi, Elena Bozzola, Fabio Mosca, Luca Degli Esposti
BACKGROUND: Respiratory syncytial virus (RSV) is among the leading causes of hospitalization due to lower respiratory tract infections (LRTIs) in children younger than 5 years worldwide and the second cause of infant death after malaria. RSV infection occurs in almost all the infants before the second year of life with variable clinical severity, often requiring medical assistance. This analysis investigated patients aged 0-5 years with RSV infection focusing on epidemiology, clinical features, and economic burden of RSV-associated hospitalizations in a setting of Italian real clinical practice...
March 25, 2024: Italian Journal of Pediatrics
https://read.qxmd.com/read/38528535/predicting-factors-for-acute-encephalopathy-in-febrile-seizure-children-with-sars-cov-2-omicron-variant-a-retrospective-study
#15
JOURNAL ARTICLE
Ching-Min Tang, Cheng-Yen Kuo, Chen-Wei Yen, Jainn-Jim Lin, Yu-Chia Hsieh, Shao-Hsuan Hsia, Oi-Wa Chan, En-Pei Lee, Po-Cheng Hung, Huei-Shyong Wang, Kuang-Lin Lin, Cheng-Hsun Chiu
BACKGROUND: SARS-CoV-2 posed a threat to children during the early phase of Omicron wave because many patients presented with febrile seizures. The study aimed to investigate predicting factors for acute encephalopathy of children infected by SARS-CoV-2 Omicron variant presenting with febrile seizures. METHODS: The retrospective study analyzed data from pediatric patients who visited the emergency department of Chang Gung Memorial Hospital in Taiwan between April and July 2022...
March 25, 2024: BMC Pediatrics
https://read.qxmd.com/read/38528394/association-of-hospital-treated-infectious-diseases-and-infection-burden-with-cardiovascular-diseases-and-life-expectancy
#16
JOURNAL ARTICLE
Jiazhen Zheng, Can Ni, S W Ricky Lee, Fu-Rong Li, Jinghan Huang, Rui Zhou, Yining Huang, Gregory Y H Lip, Xianbo Wu, Shaojun Tang
BACKGROUND: The association of a broad spectrum of infectious diseases with cardiovascular outcomes remains unclear. OBJECTIVES: We aim to provide the cardiovascular risk profiles associated with a wide range of infectious diseases and explore the extent to which infections reduce life expectancy. METHODS: We ascertained exposure to 900+ infectious diseases before cardiovascular disease (CVD) onset in 453,102 participants from the UK Biobank study...
March 25, 2024: Journal of Internal Medicine
https://read.qxmd.com/read/38528197/calcium-polystyrene-sulfonate-induced-rectal-ulcer-causing-e-coli-native-valve-infective-endocarditis
#17
JOURNAL ARTICLE
Shinnosuke Fukushima, Hideharu Hagiya, Hiroyuki Honda, Tomoharu Ishida, Ryohei Shoji, Kou Hasegawa, Fumio Otsuka
Escherichia coli-associated native-valve infective endocarditis is a rare disease that affects elderly patients with underlying risk factors such as diabetes mellitus, malignancy, and renal failure. Long-term use of calcium polystyrene sulfonate is a potential risk factor for gastrointestinal mucosal damage or even colorectal ulcers. Herein, we describe a fatal case of a 66-year-old Japanese man with diabetes mellitus and renal failure who was prescribed calcium polystyrene sulfonate (CPS) for 11 years and developed a CPS-induced rectal ulcer, leading to E...
March 25, 2024: Clinical Journal of Gastroenterology
https://read.qxmd.com/read/38527616/characteristics-management-and-outcome-of-herpes-simplex-and-varicella-zoster-virus-encephalitis-a-multicenter-prospective-cohort-study
#18
JOURNAL ARTICLE
Léa Poussier, Alexandra Mailles, Pierre Tattevin, Jean Paul Stahl, Pierre Fillatre
OBJECTIVE: To characterize differences between Herpes Simplex Virus and Varicella-Zoster Virus encephalitis (HSVE and VZVE) and other aetiologies of infectious encephalitis (IE), and to investigate the impact of time-to-aciclovir (ACV) start, ACV dose and duration on outcome. METHODS: We compared 132 HSVE, 65 VZVE, and 297 others IE enrolled in a prospective cohort (ENCEIF). We estimated associations between time-to-ACV start, dose or duration and outcome through adjusted odds-ratio (aOR) using logistic regression analysis...
March 23, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38527614/the-impact-of-the-fluconazole-trailing-effect-on-the-persistence-of-candida-albicans-bloodstream-infection-when-treated-with-fluconazole
#19
JOURNAL ARTICLE
Shang-Yi Lin, Ho-Yin Huang, Lin-Li Chang, Ya-Ling Wang, Tun-Chieh Chen, Ko Chang, Hung-Pin Tu, Po-Liang Lu
OBJECTIVES: The trailing effect of Candida species is a phenomenon characterized by reduced but persistent growth at antifungal concentrations above the minimal inhibitory concentration (MIC). We assessed the impact of trailing growth on the persistence of Candida albicans candidemia in patients receiving fluconazole therapy. METHODS: We retrospectively investigated candidemia isolates at three hospitals in southern Taiwan between 2013 and 2020. Patients treated with fluconazole for fluconazole-susceptible C...
March 23, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38527613/gut-microbiome-diversity-and-composition-in-individuals-with-and-without-extended-spectrum-%C3%AE-lactamase-producing-enterobacterales-carriage-a-matched-case-control-study-in-infectious-diseases-department
#20
JOURNAL ARTICLE
Anders Boyd, Mariam El Dani, Roula Ajrouche, Vanessa Demontant, Justine Cheval, Karine Lacombe, Guillaume Cosson, Christophe Rodriguez, Jean-Michel Pawlotsky, Paul-Louis Woerther, Laure Surgers
OBJECTIVE: Little is known on the effect of gut microbial and Extended-Spectrum β-Lactamase-Producing Enterobacterales (ESBL-E) carriage, particularly in the general population. The aim of this study was to identify microbiota signatures uniquely correlated with ESBL-E carriage. METHODS: We conducted a case-control study among individuals seeking care at the Sexual Health Clinic or Department of Infectious and Tropical Diseases at Saint-Antoine Hospital, Paris, France...
March 23, 2024: Clinical Microbiology and Infection
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