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https://www.readbyqxmd.com/read/27920996/art-strategy-for-treatment-of-recurrent-pregnancy-loss-isn-t-it-better-to-forget
#1
EDITORIAL
Mohammad Reza Sadeghi
No abstract text is available yet for this article.
October 2016: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/27918156/-cesarean-section-incidence-and-vaginal-birth-success-rate-at-term-pregnancy-after-myomectomy
#2
L Mekiňová, P Janků, E Filipinská, J Kadlecová, P Ventruba
OBJECTIVE: To compare the incidence of primary and acute cesarean section (CS) and to compare success rate of vaginal delivery. To determine the frequency of maternal complications and evaluation of post-partum condition of the newborn. STUDY DESIGN: Prospective, pilot, cohort study. SETTING: Department of Gynecology and Obstetrics Masaryk University and University Hospital Brno. METHODS: Analysis of patients with physiologically ongoing singleton pregnancy and term delivery, vertex presentation...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27917811/acute-appendicitis-in-pregnant-women-our-clinical-experience
#3
Ahmet Türkan, Metin Yalaza, Mehmet Tolga Kafadar, Gürka Değirmencioğlu
PURPOSE: The purpose of this study was to analyse 13 patients who were treated in our clinic due to acute appendicitis during pregnancy. METHODS: Records of the patients who received appendectomy with appendicitis diagnosis in our Turgut Özal University Research and Application Hospital between January 2007 and December 2015 have been analyzed retrospectively. RESULTS: Appendectomies were performed on 13 pregnant patients with an acute appendicitis diagnosis...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27917469/association-of-dysfunctional-synapse-defective-1-syde1-with-restricted-fetal-growth-syde1-regulates-placental-cell-migration-and-invasion
#4
Hsiao-Fan Lo, Ching-Yen Tsai, Chie-Pein Chen, Liang-Jie Wang, Yun-Shien Lee, Chia-Yu Chen, Chung-Tiang Liang, Mei-Leng Cheong, Hungwen Chen
The transcription factor glial cells missing 1 (GCM1) regulates trophoblast differentiation and function during placentation. Decreased GCM1 expression is associated with preeclampsia, suggesting that abnormal expression of GCM1 target genes may contribute to the pathogenesis of pregnancy complications. Here we identified a novel GCM1 target gene, synapse defective 1 (SYDE1), which encodes a RhoGAP that is highly expressed in human placenta, and demonstrated that SYDE1 promotes cytoskeletal remodelling and cell migration and invasion...
December 5, 2016: Journal of Pathology
https://www.readbyqxmd.com/read/27913250/identification-of-non-coding-and-coding-rnas-in-porcine-endometrium
#5
Yueying Wang, Tao Hu, Lihang Wu, Xiaoran Liu, Songyi Xue, Minggang Lei
One of the most critical periods of embryonic loss in pig is day 12 of pregnancy, when implantation begins. Here, we analyzed the gene expression on day 12 of pregnancy and non-pregnancy in the porcine endometrium using RNA sequencing (RNA-seq). 237 mRNAs, 34 lncRNAs and 1 miRNA were significantly differentially expressed between the two groups. Further functional analyses were conducted to identify these differentially expressed transcripts. The results demonstrated that they participate in various biological processes, such as cell adhesion, binding, nucleic and metabolic processes...
November 29, 2016: Genomics
https://www.readbyqxmd.com/read/27904309/robot-assisted-abdominal-cerclage-during-pregnancy
#6
Burak Zeybek, Amanda Hill, Gulden Menderes, Mostafa A Borahay, Masoud Azodi, Gokhan Sami Kilic
BACKGROUND AND OBJECTIVES: Cervical insufficiency is a difficult condition to diagnose and can lead to preterm birth, miscarriage, or perinatal infant morbidity and mortality. We conducted this retrospective case study and literature review to evaluate the safety and efficacy of robot-assisted abdominal cerclage during pregnancy. METHODS: We conducted a case series and a systematic review that included patients who underwent robot-assisted abdominal cerclage during pregnancy from January 2010 through March 2016...
October 2016: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/27903074/bicornuate-uterus-is-an-independent-risk-factor-for-cervical-os-insufficiency-a-retrospective-population-based-cohort-study
#7
Salvatore Andrea Mastrolia, Yael Baumfeld, Reli Hershkovitz, Giuseppe Loverro, Edoardo Di Naro, David Yohai, Polina Schwarzman, Adi Yehuda Weintraub
INTRODUCTION: The purpose of our study was to explore maternal and fetal outcomes in the second and third trimester in women with bicornuate uterus. METHODS: A total of 280,106 pregnancies met the inclusion criteria and were divided in two study groups: (1) pregnancies in women with bicornuate uterus (n = 444); and (2) controls (n = 279,662). The diagnosis of bicornuate uterus was performed in all patients during the workup for infertility or recurrent pregnancy loss, during pregnancy, or at the time of cesarean delivery...
December 1, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27902772/relation-between-birth-weight-and-intraoperative-hemorrhage-during-cesarean-section-in-pregnancy-with-placenta-previa
#8
Hiroaki Soyama, Morikazu Miyamoto, Hiroki Ishibashi, Masashi Takano, Hidenori Sasa, Kenichi Furuya
BACKGROUND: Placenta previa, one of the most severe obstetric complications, carries an increased risk of intraoperative massive hemorrhage. Several risk factors for intraoperative hemorrhage have been identified to date. However, the correlation between birth weight and intraoperative hemorrhage has not been investigated. Here we estimate the correlation between birth weight and the occurrence of intraoperative massive hemorrhage in placenta previa. MATERIALS AND METHODS: We included all 256 singleton pregnancies delivered via cesarean section at our hospital because of placenta previa between 2003 and 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27902507/smoking-hiv-and-risk-of-pregnancy-loss
#9
Daniel Westreich, Jordan Cates, Mardge Cohen, Kathleen M Weber, Dominika Seidman, Karen Cropsey, Rodney Wright, Joel Milam, Mary A Young, C Christina Mehta, Deborah R Gustafson, Margaret A Fischl, Adaora A Adimora
OBJECTIVE: Cigarette smoking during pregnancy increases risks of poor pregnancy outcomes including miscarriage and stillbirth (pregnancy loss), but the effect of smoking on pregnancy loss among HIV-infected women has not been explored. Here, investigated the impact of smoking on risk of pregnancy loss among HIV-positive and HIV-negative women, and estimated the potential impact of realistic smoking cessation interventions on risk of pregnancy loss among HIV-positive women. DESIGN: We analyzed pregnancy outcomes in HIV-positive and HIV-negative participants in the Women's Interagency HIV Study (WIHS) between 1994 and 2014...
November 29, 2016: AIDS
https://www.readbyqxmd.com/read/27896374/loss-of-group-memberships-predicts-depression-in-postpartum-mothers
#10
Magen Seymour-Smith, Tegan Cruwys, S Alexander Haslam, Wendy Brodribb
PURPOSE: The postpartum period presents the highest risk for women's mental health throughout the lifespan. We aimed to examine the Social Identity Model of Identity Change in this context. More specifically, we investigated changes in social identity during this life transition and their consequences for women's postpartum mental health. METHODS: Women who had given birth within the last 12 months (N = 387) reported on measures of depression, social group memberships, and motherhood identification...
November 28, 2016: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/27894063/loss-of-glutaredoxin-3-impedes-mammary-lobuloalveolar-development-during-pregnancy-and-lactation
#11
Khanh Pham, Jie Dong, Xiqian Jiang, Ying Qu, Han Yu, Yisheng Yang, Walter Olea, Juan C Marini, Lawrence Chan, Jin Wang, Xander H T Wehrens, Xiaojiang Cui, Yi Li, Darryl L Hadsell, Ninghui Cheng
Mammalian glutaredoxin 3 (Grx3) has been shown to be important for regulating cellular redox homeostasis in the cell. Our previous studies indicate that Grx3 is significantly overexpressed in various human cancers including breast cancer and demonstrate that Grx3 controls cancer cell growth and invasion by regulating ROS and NF-κB signaling pathways. However, it remains to be determined whether Grx3 is required for normal mammary gland development and how it contributes to epithelial cell proliferation and differentiation in vivo In the present study, we examined Grx3 expression in different cell types within the developing mouse mammary gland (MG) and found enhanced expression of Grx3 at pregnancy and lactation stages...
November 15, 2016: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27893540/eight-years-experience-of-sentinel-lymph-node-biopsy-in-melanoma-using-lymphoscintigraphy-and-gamma-probe-detection-after-radiocolloid-mapping
#12
Nathalie Pham Dang, Sophie Cassier, Aurélien Mulliez, Sandrine Mansard, Michel DʼIncan, Isabelle Barthélémy
BACKGROUND: Isosulfan blue dye peripheral injection is used in preoperative sentinel lymph node (SLN) identification alone or, to increase sensitivity, in conjunction with radiocolloid mapping. However, isosulfan blue dye has certain drawbacks and limitations. OBJECTIVE: This study assesses the authors' experience of SLN biopsy using only radiocolloid tracer. MATERIALS AND METHODS: Between 2000 and 2008, 218 patients underwent SLN biopsy with radiocolloid mapping, preoperative localization by lymphoscintigraphy and intraoperative confirmation by gamma probe in primary malignant cutaneous melanoma...
November 23, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27891347/decidual-cd56-natural-killer-cells-in-spontaneous-early-pregnancy-loss-an-immunohistochemical-study
#13
Balamurugan Senthilnayagam, Sridhar Karthikeyan, Jayapriya Sukumaran, Anoop Srivalsan, Ramesh Rao, Vasantha Subbiah
INTRODUCTION: Natural killer cells are believed to promote placental and trophoblastic growth and provide immune- modulation at maternal-fetal interface in pregnancy and their role in reproductive failure has been a matter of discussion. AIM: To study CD56+ Natural killer cells in spontaneous pregnancy loss. MATERIALS AND METHODS: In this prospective observational study, formalin-fixed paraffin embedded sections from products of conception from twenty women each with spontaneous early pregnancy loss (test group) and elective pregnancy termination (control group)...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891325/effect-of-tocopheryl-acetate-on-maternal-cigarette-smoke-exposed-swiss-albino-mice-inbred-fetus
#14
Janardan Chaudhary, Royana Singh, S N Shamal, K Supriya, Mona Srivastava, R S More
INTRODUCTION: Cigarette smoking is worldwide problem which can be correlated with teratogenicity. Tocopheryl acetate plays as an antioxidant against the oxidative stress evolved by cigarette smoke exposure during pregnancy. AIM: To study the effect of maternal exposure to cigarette smoke and Tocopheryl acetate on fetuses of mice. MATERIALS AND METHODS: Pregnant mice randomly assigned to different groups (Group I (control), Group II (Tocopheryl acetate), Group III(soyabean oil used as vehicle for Tocopheryl acetate), Group IV (Cigarette smoke Exposed), Group V (Cigarette smoke exposed plus Tocopheryl acetate) and Group VI(Cigarette smoke exposed plus soyabean oil) were exposed to cigarette smoke 3 times a day for 20 minutes each time and Tocopheryl acetate with dose of 200mg/kg/day in 0...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27888752/factors-influencing-brain-natriuretic-peptide-levels-in-healthy-pregnant-women
#15
Michinori Mayama, Masato Yoshihara, Kaname Uno, Sho Tano, Takehiko Takeda, Mayu Ukai, Yasuyuki Kishigami, Hidenori Oguchi
BACKGROUND: The normal range of plasma brain natriuretic peptide (BNP) in pregnant women is still unclear. Moreover, pregnant women experience dynamic body weight changes and suffer from anemia, but effects on maternal BNP have not been investigated. This study aimed to reveal the normal plasma BNP range and examine the effects of physiological changes on BNP among pregnant women. METHODS AND RESULTS: Plasma BNP, hemoglobin, plasma creatinine and BMI were measured in 58 non-pregnant control women and in 773 normal pregnant women at late pregnancy, early postpartum and 1-month postpartum...
November 10, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27888033/prenatal-intake-of-vitamins-and-allergic-outcomes-in-the-offspring-a-systematic-review-and-meta-analysis
#16
Mariam Vahdaninia, Heather Mackenzie, Suzannah Helps, Taraneh Dean
BACKGROUND: Allergic diseases have seen a rise worldwide, with children suffering the highest burden. Thus, early prevention of allergic diseases is a public health priority. OBJECTIVE: To synthesize the evidence from randomized controlled trials (RCTs) assessing the effect of vitamin interventions during pregnancy on developing allergic diseases in offspring. METHODS: We searched CENTRAL, MEDLINE, SCOPUS, World Health Organization's International Clinical Trials Registration, E-theses, and Web of Science...
November 22, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27884847/long-term-mortality-in-mothers-with-perinatal-losses-and-risk-modification-by-surviving-children-and-attained-education-a-population-based-cohort-study
#17
Frode Halland, Nils-Halvdan Morken, Lisa A DeRoo, Kari Klungsøyr, Allen J Wilcox, Rolv Skjærven
OBJECTIVE: To assess the association between perinatal losses and mother's long-term mortality and modification by surviving children and attained education. DESIGN: A population-based cohort study. SETTING: Norwegian national registries. PARTICIPANTS: We followed 652 320 mothers with a first delivery from 1967 and completed reproduction before 2003, until 2010 or death. We excluded mothers with plural pregnancies, without information on education (0...
November 24, 2016: BMJ Open
https://www.readbyqxmd.com/read/27883173/clinical-application-of-snp-array-analysis-in-first-trimester-pregnancy-loss-a-prospective-study
#18
Yan Wang, Qing Cheng, Lulu Meng, Chunyu Luo, Huanran Hu, Jingjing Zhang, Jian Cheng, Tianhui Xu, Tao Jiang, Dong Liang, Ping Hu, Zhengfeng Xu
Chromosomal microarray analysis (CMA) has been used routinely in pediatric and prenatal genetic diagnosis in clinical practice, but it has rarely been applied to miscarriage analysis. In this study, we conducted a prospective study to evaluate the feasibility of CMA for genetic diagnosis of first-trimester miscarriage specimens. We successfully analyzed 551 fresh miscarriage specimens using SNP array. Among the specimens, 2.9% (16/551) had significant maternal cell contamination and were excluded from the study...
November 24, 2016: Clinical Genetics
https://www.readbyqxmd.com/read/27882764/-acute-pancreatitis-in-pregnancy-complicated-by-rupture-of%C3%A2-aneurysm-of-artery-lienalis
#19
E Hostinská, K Huml, R Pilka
OBJECTIVE: We present a case of pregnant woman with acute pacreatitis in 38th week comlicated by acute rupture of aneurysm of artery lienalis. DESIGN: Case report. SETTING: Department of Gynaecology and Obstetrics, Faculty Hospital and Palacky University, Olomouc. CASE REPORT: 28-years-old primipara in 38th week of gestation was admitted to our department for acute pancreatitis caused by gallstones. Subsequent conservative treatment was complicated by rupture of aneurysm of lienal artery and haemorrhagic shock...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27881737/rankl-rank-from-bone-loss-to-the-prevention-of-breast-cancer
#20
REVIEW
Verena Sigl, Laundette P Jones, Josef M Penninger
RANK and RANKL, a receptor ligand pair belonging to the tumour necrosis factor family, are the critical regulators of osteoclast development and bone metabolism. Besides their essential function in bone, RANK and RANKL have also been identified as the key factors for the formation of a lactating mammary gland in pregnancy. Mechanistically, RANK and RANKL link the sex hormone progesterone with stem cell expansion and proliferation of mammary epithelial cells. Based on their normal physiology, RANKL/RANK control the onset of hormone-induced breast cancer through the expansion of mammary progenitor cells...
November 2016: Open Biology
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