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https://www.readbyqxmd.com/read/29777952/the-opportunity-to-avoid-pain-may-paradoxically-increase-fear
#1
Christine M van Vliet, Ann Meulders, Linda M G Vancleef, Johan W S Vlaeyen
Fear-avoidance models propose that pain-related fear may spur avoidance behaviour leading to chronic pain disability. Pain-related fear elicits avoidance behaviour, which is typically aimed at reducing fear. We hypothesized that engaging in avoidance may (paradoxically) increase rather than decrease pain-related fear (i.e. bidirectionality hypothesis). In a between-subject design, participants (N=64) were randomly assigned to the avoidance group or the control group. Avoidance group participants were led to believe they could avoid full exposure to a painful heat stimulus by pressing the stop-button, while control group participants believed they were exposed to the full painful heat stimulus at all times...
May 16, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29777676/cognitive-effects-of-rhythmic-auditory-stimulation-in-parkinson-s-disease-a-p300-study
#2
Juan Lei, Nadine Conradi, Cornelius Abel, Stefan Frisch, Alla Brodski-Guerniero, Marcel Hildner, Christian A Kell, Jochen Kaiser, Maren Schmidt-Kassow
Rhythmic auditory stimulation (RAS) may compensate dysfunctions of the basal ganglia (BG), involved with intrinsic evaluation of temporal intervals and action initiation or continuation. In the cognitive domain, RAS containing periodically presented tones facilitates young healthy participants' attention allocation to anticipated time points, indicated by better performance and larger P300 amplitudes to periodic compared to random stimuli. Additionally, active auditory-motor synchronization (AMS) leads to a more precise temporal encoding of stimuli via embodied timing encoding than stimulus presentation adapted to the participants' actual movements...
May 16, 2018: Brain Research
https://www.readbyqxmd.com/read/29777667/properties-and-units-in-the-clinical-laboratory-sciences-part-xxiv-properties-and-units-in-clinical-molecular-genetics-technical-report-2017
#3
Ulla M Petersen, Ariadna Padró Miquel, Graham Taylor, Jens Michael Hertz, Rebecca Ceder, Xavier Fuentes Arderiu, Johan T den Dunnen
This document describes the application of the syntax, semantic rules, and format of the Nomenclature for Properties and Units (NPU) terminology for coded dedicated kinds-of-property in the subject field of clinical molecular genetics. A vocabulary for NPU definitions in this field, based on international terminology and nomenclature, is introduced; examples of actual NPU definitions for different types of investigations are given and explained.
May 16, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29777604/-ethical-aspects-of-the-use-of-mirena-r-iud-in-the-treatment-of-heavy-menstrual-bleeding
#4
Miriam Turiel Miranda, Pau Agulles Simó
The levonorgestrel-releasing intrauterine device known as Mirena IUD(r) (20mcg/24h) is nowadays considered among the leading resources in the treatment of heavy menstrual bleeding. Nonetheless, due to either its effect of prevention of conception and especially to the possibility that it may also have an anti-implantation effect, there is a founded concern on whether its therapeutic use may be ethically licit. This article engages in an exhaustive literature review in order to ascertain the mechanism of action of Mirena(r) IUD, in view of an ethical evaluation of its therapeutic use, keeping in mind those two unwanted effects...
May 2018: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/29777566/care-provider-allocation-on-admissions-to-acute-mental-health-wards-the-development-and-validation-of-the-admission-team-score-list
#5
Sjobha R N van den Berg, Barbara Stringer, Roland van de Sande, Stasja Draisma
Currently, support tools are lacking to prioritize steps in the care coordination process to enable safe practice and effective clinical pathways in the first phase of acute psychiatric admissions. This study describes the development, validity, and reliability of an acute care coordination support tool, the Admission Team Score List (ATSL). The ATSL assists in care provider allocation during admissions. Face validity and feasibility of the ATSL were tested in 77 acute admissions. Endscores of filled out ATSL's were translated to recommended team compositions...
May 18, 2018: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/29777506/an-extended-kalman-filter-for-mouse-tracking
#6
Hongjun Choi, Mingi Kim, Onseok Lee
Animal tracking is an important tool for observing behavior, which is useful in various research areas. Animal specimens can be tracked using dynamic models and observation models that require several types of data. Tracking mouse has several barriers due to the physical characteristics of the mouse, their unpredictable movement, and cluttered environments. Therefore, we propose a reliable method that uses a detection stage and a tracking stage to successfully track mouse. The detection stage detects the surface area of the mouse skin, and the tracking stage implements an extended Kalman filter to estimate the state variables of a nonlinear model...
May 19, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29777243/comparison-of-formulae-for-orotracheal-intubation-depth-in-the-paediatric-population
#7
Jen Heng Pek, Elizabeth Mj Tan, Ying Hao, Gene Yk Ong
INTRODUCTION: Multiple formulae have been proposed for calculating orotracheal depth for paediatric intubation. However, literature on the validation of these formulae in the emergency department setting is limited. Three methods described in the local Advanced Paediatric Life Support curriculum include the Broselow tape, endotracheal tube (ETT) size x 3, and the age-based formula of age divided by 2, add 12. We aimed to determine their accuracy. MATERIALS AND METHODS: Patients with intubation performed in the Children's Emergency from 1 January 2009 to 31 December 2013 were included in this retrospective observational study...
April 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29777129/passive-millimeter-wave-imaging-system-based-on-helical-scanning
#8
Yang Meng, Anyong Qing, Chuan Lin, Jiefeng Zang, Yizhe Zhao, Cheng Zhang
A simple and fast single channel passive millimeter wave (PMMW) imaging system for public security check is presented in this paper. It distinguishes itself with traditional ones by an innovative scanning mechanism. Indoor experiments against human body with or without concealed items in clothes show that imaging could be completed in 3 s with angular resolution of about 0.7°. In addition, its field of view (FOV) is adjustable according to the size of actual target.
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29777060/protease-activated-receptor-1-inhibits-cholesterol-efflux-and-promotes-atherogenesis-via-cullin-3-mediated-degradation-of-the-abca1-transporter
#9
Somasundaram Raghavan, Nikhlesh K Singh, Arul M Mani, Gadiparthi N Rao
Although signaling of thrombin via its receptor protease-activated receptor 1 (Par1) is known to occur in atherothrombosis, its link to the actual pathogenesis of this condition is less clear. To better understand the role of thrombin-Par1 signaling in atherosclerosis, here we have studied their effects on cellular cholesterol efflux in mice. We found that by activating Par1 and cullin 3-mediated ubiquitination and degradation of ATP-binding cassette subfamily A member 1 (ABCA1), thrombin inhibits cholesterol efflux in both murine macrophages and smooth muscle cells...
May 18, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29776841/-medical-simulation-as-a-tool-in-the-training-of-perinatal-professionals
#10
B Tosello, J Blanc, C Kelway, V Pellegrin, E Quarello, F Comte, C Zakarian, C D'Ercole
Though technology plays an increasingly important role in modern health systems, human performance remains a major determinant of safety, effectiveness and efficiency of patient care. This is especially true in the delivery room. Thus, the training of professionals must aim not only for the acquisition of theory and practical skills on an individual basis, but also for the learning of teamwork systematically. Training health professionals with simulation enhances their theoretical knowledge and meets formal requirements in literacy, technical skills and communication...
May 15, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29776674/migration-behavior-of-organic-dyes-based-on-physicochemical-properties-of-solvents-as-background-electrolytes-in-non-aqueous-capillary-electrophoresis
#11
Minjeong Gu, Keunchang Cho, Seong Ho Kang
The migration behavior of organic fluorescent dyes (i.e., crystal violet, methyl violet base, methyl violet B base, rhodamine 6G, and rhodamine B base) in non-aqueous capillary electrophoresis (NACE) was investigated by focusing on the physicochemical properties of various organic solvents [ethanol, methanol, 2-propanol, dimethylformamide (DMF), and dimethyl sulfoxide (DMSO)] in background electrolyte (BGE). Laser-induced fluorescence (LIF) and UV/Vis detectors were employed to observe both the migration time of organic dyes and the electroosmotic flow (EOF) in NACE, respectively...
May 15, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29776586/-the-role-and-use-of-patient-reported-outcomes-in-the-management-of-cancer-patients
#12
REVIEW
Patricia Marino, Marie Bannier, Jean-François Moulin, Gwenaëlle Gravis
Therapeutic innovations in the field of oncology allow to manage cancer as a chronic illness with treatments being administered over prolonged periods of time. In this context, it is now acknowledged that it is important to complete the assessment of benefit based on purely clinical endpoints using outcome measurement evaluated by patients themselves. The Patient reported outcome (PRO) concept has then emerged and there is an increasing interest in using the PROs as an indicator of the benefit of new therapeutic strategies...
May 15, 2018: Bulletin du Cancer
https://www.readbyqxmd.com/read/29776526/access-to-trauma-centers-for-road-crashes-in-the-united-states
#13
Wei Hu, Qiao Dong, Chunjiao Dong, Jun Yang, Baoshan Huang
INTRODUCTION: Existing research indicates that around 90% of all U.S. residents have access to at least one level I or II trauma center within 60min. However, a limitation of these estimates lies in that they are based on where people live and not where people are injured, which may overestimate the access to trauma centers for seriously injured patients in fatal crashes. METHOD: In this study, the Fatality Analysis Reporting System (FARS) data between 2013 and 2014 were collected and analyzed to quantify the access of injured patients to trauma centers for fatal crashes across states...
June 2018: Journal of Safety Research
https://www.readbyqxmd.com/read/29776370/characterization-of-a-promiscuous-cadmium-and-arsenic-resistance-mechanism-in-thermus-thermophilus-hb27-and-potential-application-of-a-novel-bioreporter-system
#14
Immacolata Antonucci, Giovanni Gallo, Danila Limauro, Patrizia Contursi, Ana Luisa Ribeiro, Alba Blesa, José Berenguer, Simonetta Bartolucci, Gabriella Fiorentino
BACKGROUND: The characterization of the molecular determinants of metal resistance has potential biotechnological application in biosensing and bioremediation. In this context, the bacterium Thermus thermophilus HB27 is a metal tolerant thermophile containing a set of genes involved in arsenic resistance which, differently from other microbes, are not organized into a single operon. They encode the proteins: arsenate reductase, TtArsC, arsenic efflux membrane transporter, TtArsX, and transcriptional repressor, TtSmtB...
May 18, 2018: Microbial Cell Factories
https://www.readbyqxmd.com/read/29776042/modeling-long-correlation-times-using-additive-binary-markov-chains-applications-to-wind-generation-time-series
#15
Juliane Weber, Christopher Zachow, Dirk Witthaut
Wind power generation exhibits a strong temporal variability, which is crucial for system integration in highly renewable power systems. Different methods exist to simulate wind power generation but they often cannot represent the crucial temporal fluctuations properly. We apply the concept of additive binary Markov chains to model a wind generation time series consisting of two states: periods of high and low wind generation. The only input parameter for this model is the empirical autocorrelation function...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776034/derivation-of-markov-processes-that-violate-detailed-balance
#16
Julian Lee
Time-reversal symmetry of the microscopic laws dictates that the equilibrium distribution of a stochastic process must obey the condition of detailed balance. However, cyclic Markov processes that do not admit equilibrium distributions with detailed balance are often used to model systems driven out of equilibrium by external agents. I show that for a Markov model without detailed balance, an extended Markov model can be constructed, which explicitly includes the degrees of freedom for the driving agent and satisfies the detailed balance condition...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776011/predicting-nonadherence-to-adjuvant-endocrine-therapy-in-women-with-early-stage-breast-cancer
#17
Arden L Corter, Reuben Broom, David Porter, Vernon Harvey, Michael Findlay
BACKGROUND: Failing to take endocrine therapy (ET) as prescribed (nonadherence) increases risk of morbidity and mortality from breast cancer recurrence. We explored predictors of nonadherence, including demographic, clinical, treatment and personal factors, among women newly prescribed ET for early stage breast cancer. We also examined predictors of their thoughts about stopping treatment (TST). METHODS: A baseline survey prior to ET assessed demographics, illness beliefs, beliefs about medicines, fear of recurrence, symptoms and negative affect...
May 18, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29775928/tributyltin-impaired-reproductive-success-in-female-zebrafish-through-disrupting-oogenesis-reproductive-behaviors-and-serotonin-synthesis
#18
Wei-Yang Xiao, Ying-Wen Li, Qi-Liang Chen, Zhi-Hao Liu
Tributyltin (TBT), an organotin acting as aromatase (Cyp19a1) inhibitor, has been found to disrupt gametogenesis and reproductive behaviors in several fish species. However, few studies addressing the mechanisms underlying the impaired gametogenesis and reproduction have been reported. In this study, female adults of zebrafish (Danio rerio) were continuously exposed to two nominal concentrations of TBT (100 and 500 ng/L, actual concentrations: 90.8 ± 1.3 ng/L and 470.3 ± 2.7 ng/L, respectively) for 28 days...
May 12, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29775841/cesium-desorption-behavior-of-weathered-biotite-in-fukushima-considering-the-actual-radioactive-contamination-level-of-soils
#19
Hiroki Mukai, Kenji Tamura, Ryosuke Kikuchi, Yoshio Takahashi, Tsuyoshi Yaita, Toshihiro Kogure
For the better understanding of radioactive contamination in Fukushima Prefecture at present and in future, Cs desorption experiments have been conducted mainly using weathered biotite (WB) collected from Fukushima Prefecture and considering the actual contamination level (∼10-10  wt%) of radiocesium in Fukushima Prefecture. In the experiments, 137 Cs sorbed to WB by immersing in 137 Cs solution for one day was mostly desorbed by solutions of 1 M NaNO3 , 1 M LiNO3 , 10-1  M HCl, and 10-1  M HNO3 , although it was barely desorbed by 1 M KNO3 , 1 M CsNO3 , 1 M NH4 NO3 , and natural seawater...
May 15, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29775771/a-detailed-analysis-of-the-arden-syntax-expression-grammar
#20
Stefan Kraus, Marc Rosenbauer, Lutz Schröder, Thomas Bürkle, Klaus-Peter Adlassnig, Dennis Toddenroth
OBJECTIVE: The Arden Syntax for Medical Logic Systems is a standard for encoding and sharing medical knowledge in the form of Medical Logic Modules. To improve accessibility for clinicians, the originators of the standard deliberately designed Arden Syntax expressions to resemble natural language, and parentheses around operands are not generally required. For certain patterns of nested expressions, however, the use of parentheses is mandatory, otherwise they are not accepted by an Arden Syntax environment...
May 15, 2018: Journal of Biomedical Informatics
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