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https://www.readbyqxmd.com/read/29041475/sub-shot-noise-shadow-sensing-with-quantum-correlations
#1
Ermes Toninelli, Matthew P Edgar, Paul-Antoine Moreau, Graham M Gibson, Giles D Hammond, Miles J Padgett
The quantised nature of the electromagnetic field sets the classical limit to the sensitivity of position measurements. However, techniques based on the properties of quantum states can be exploited to accurately measure the relative displacement of a physical object beyond this classical limit. In this work, we use a simple scheme based on the split-detection of quantum correlations to measure the position of a shadow at the single-photon light level, with a precision that exceeds the shot-noise limit. This result is obtained by analysing the correlated signals of bi-photon pairs, created in parametric downconversion and detected by an electron multiplying CCD (EMCCD) camera employed as a split-detector...
September 4, 2017: Optics Express
https://www.readbyqxmd.com/read/29041371/dependence-of-measured-audio-band-squeezing-level-on-local-oscillator-intensity-noise
#2
Wenhai Yang, Xiaoli Jin, Xudong Yu, Yaohui Zheng, Kunchi Peng
We investigate the dependence of the measured squeezing level on the local oscillator (LO) intensity noise. The theoretical results indicate that it produces a large measurement error with the increase of the LO intensity noise, but the measurement error has immunity to the product P of the common mode rejection ratio (CMRR) with the LO intensity noise. According to the investigation results and the LO intensity noise, we employ a detector with the CMRR of 67 dB to detect the quantum noise at audio frequencies, the product P of the CMRR with the LO intensity noise is 20 dB below the shot noise limit (SNL), which can induce the measurement error of 0...
October 2, 2017: Optics Express
https://www.readbyqxmd.com/read/29040832/biological-evaluation-of-surface-modified-magnetic-nanoparticles-as-a-platform-for-colon-cancer-cell-theranostics
#3
Maksym Moskvin, Michal Babič, Salette Reis, M Margarida Cruz, Liliana P Ferreira, Maria Deus Carvalho, Sofia A Costa Lima, Daniel Horák
Magnetic nanoparticles offer multiple possibilities for biomedical applications. Besides their physico-chemical properties, nanoparticle-cellular interactions are determinant for biological safety. In this work, magnetic nanoparticles were synthesized by one-shot precipitation or two-step reaction and coated with biocompatible polymers, such as poly(l-lysine) and poly(N,N-dimethylacrylamide-co-acrylic acid), and carbohydrates, like l-ascorbic acid, d-galactose, d-mannose, and sucrose. The resulting magnetic nanoparticles were characterized by dynamic light scattering, FT-Raman spectroscopy, transmission electron microscopy, SQUID magnetometry, and Mössbauer spectroscopy...
October 12, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29040231/continuous-infraclavicular-brachial-block-versus-single-shot-nerve-block-for-distal-radius-surgery-a-prospective-randomized-control-trial
#4
Abhishek Ganta, David Ding, Nina Fisher, Jessica Lavery, Sudheer Jain, Nirmal Tejwani
OBJECTIVES: To compare the efficacy of an infraclaviclar single shot nerve block to a continuous infusion through an On Q infusion pump for rebound pain (between 12 to 24 hours post-operatively) and post operative narcotic analgesia requirements in distal radius fractures. DESIGN: Prospective Randomized Control Trial SETTINGS:: Performed at two hospitals affiliated with a large urban academic medical center PATIENTS:: Fifty patients undergoing operative fixation of distal radius fractures (OTA/AO type 23B/C) INTERVENTION:: Patients were randomized to receive either an infraclavicular block as a single shot (SSB group) or a continuous infusion through an On Q pump (On Q group) MAIN OUTCOME MEASURES:: Visual analog scale (0-10) pain levels and amount of pain medication taken RESULTS:: At all time points after discharge, mean post-operative pain scores were lower in the On Q group vs the SSB group but did not reach statistical significance...
September 1, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29039153/postoperative-analgesia-after-arthroscopic-shoulder-surgery-a-comparison-between-single-shot-interscalene-block-and-single-shot-supraclavicular-block
#5
Ahmet Kemalettin Koltka, Mehmet Büget, Emre Sertaç Bingül, Ali Erşen, Süleyman Küçükay, Ata Can Atalar, Mert Şentürk
OBJECTIVES: In arthroscopic rotator cuff surgery for postoperative analgesia opioids, nonsteroid analgesics, and local anesthetics can be used. This study aimed to compare the effectiveness, additional analgesic requirements, patients satisfaction, and complications of single-shot interscalene and supraclavicular blocks. METHODS: After obtaining the ethics committee's approval and informed consent, 50 ASA I-II patients were randomized to either the interscalene (GISB) or supraclavicular (GSCB) group...
July 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/29038580/a-novel-library-of-arylketones-as-potential-inhibitors-of-%C3%AE-glucosidase-their-design-synthesis-in-vitro-and-in-vivo-studies
#6
Tania Luthra, Rahul Agarwal, Mamidala Estari, Uma Adepally, Subhabrata Sen
α-glucosidase is an essential enzyme located at the brush border of intestines. It is an important therapeutic target for type II diabetes. Herein we have designed a library of novel α-arylketones as inhibitors of α-glucosidase (yeast origin) via scaffold hopping and bioisosteric modification of known inhibitors of α-glucosidase. The design was validated through molecular docking that revealed strong binding interactions of the newly designed compounds against α-glucosidase. A library comprising of 15 compounds was synthesized in a combinatorial fashion, where the advanced amide intermediates were accessed through "shot gun" synthesis...
October 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29032903/single-shot-femoral-nerve-block-does-not-cause-long-term-strength-and-functional-deficits-following-anterior-cruciate-ligament-reconstruction
#7
Kelechi R Okoroha, Lafi Khalil, Edward K Jung, Robert A Keller, Nathan E Marshall, Moneer Abouljoud, Derek Chan, Vasilios Moutzouros
PURPOSE: To determine if patients treated with a single-shot femoral nerve block have strength and functional deficits at 9-month follow-up. METHODS: Forty-three patients who underwent primary anterior cruciate ligament reconstructions were randomized to receive either a preoperative single-shot femoral nerve block or local infiltration anesthesia for primary pain control. All patients underwent a standardized comprehensive rehabilitation program postoperatively...
October 9, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29030668/desktop-nmr-spectroscopy-for-real-time-monitoring-of-an-acetalization-reaction-in-comparison-with-gas-chromatography-and-nmr-at-9-4%C3%A2-t
#8
Kawarpal Singh, Ernesto Danieli, Bernhard Blümich
Monitoring of chemical reactions in real-time is in demand for process control. Different methods such as gas chromatography (GC), mass spectroscopy, infrared spectroscopy, and nuclear magnetic resonance (NMR) are used for that purpose. The current state-of-the-art compact NMR systems provide a useful method to employ with various reaction conditions for studying chemical reactions inside the fume hood at the chemical workplace. In the present study, an acetalization reaction was investigated with compact NMR spectroscopy in real-time...
October 13, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29021912/a-study-of-intensity-fatigue-and-precision-in-two-specific-interval-trainings-in-young-tennis-players-high-intensity-interval-training-versus-intermittent-interval-training
#9
David Suárez Rodríguez, Miguel Del Valle Soto
BACKGROUND: The aim of this study is to find the differences between two specific interval exercises. We begin with the hypothesis that the use of microintervals of work and rest allow for greater intensity of play and a reduction in fatigue. METHODS: Thirteen competition-level male tennis players took part in two interval training exercises comprising nine 2 min series, which consisted of hitting the ball with cross-court forehand and backhand shots, behind the service box...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29016475/relationship-between-physiological-off-ice-testing-on-ice-skating-and-game-performance-in-division-i-women-s-ice-hockey-players
#10
Michelle Boland, Emily M Miele, Katie Delude
The purpose was to identify off-ice testing variables that correlate to skating and game performance in Division I collegiate women ice hockey players. Twenty female, forward and defensive players (19.95 ± 1.35 yr) were assessed for weight, height, percent fat mass (%FAT), bone mineral density, predicted one repetition maximum (RM) absolute and relative (REL%) bench press (BP) and hex bar deadlift (HDL), lower body explosive power, anaerobic power, countermovement vertical jump (CMJ), maximum inspiratory pressure (MIP), and on-ice repeated skate sprint (RSS) performance...
October 7, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28991122/peripheral-nerve-blocks-for-hip-fractures-a-cochrane-review
#11
Joanne Guay, Martyn J Parker, Richard Griffiths, Sandra L Kopp
BACKGROUND: This review focuses on the use of peripheral nerve blocks as preoperative analgesia, as postoperative analgesia, or as a supplement to general anesthesia for hip fracture surgery and tries to determine if they offer any benefit in terms of pain on movement at 30 minutes after block placement, acute confusional state, myocardial infarction/ischemia, pneumonia, mortality, time to first mobilization, and cost of analgesic. METHODS: Trials were identified by computerized searches of Cochrane Central Register of Controlled Trials (2016, Issue 8), MEDLINE (Ovid SP, 1966 to 2016 August week 1), Embase (Ovid SP, 1988 to 2016 August week 1), and the Cumulative Index to Nursing and Allied Health Literature (EBSCO, 1982 to 2016 August week 1), trials registers, and reference lists of relevant articles...
October 4, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28987676/value-of-diffusion-tensor-imaging-in-differentiating-malignant-from-benign-parotid-gland-tumors
#12
Koji Takumi, Yoshihiko Fukukura, Hiroto Hakamada, Junichi Ideue, Yuichi Kumagae, Takashi Yoshiura
PURPOSE: To evaluate whether diffusion tensor imaging (DTI) can be used to differentiate malignant parotid gland tumors from the benign ones. MATERIALS AND METHODS: The study population comprised 59 parotid gland tumors (24 Warthin's tumors, 19 pleomorphic adenomas, seven other benign tumors, and nine malignant tumors). Single-shot echo-planar DTI was performed with motion-probing gradients along 30 noncollinear directions (b=1000s/mm(2)) at 3.0T. Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values for benign and malignant tumors were compared using the Mann-Whitney U test...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28969239/magnetic-resonance-imaging-in-paediatric-spinal-dysraphism-with-comparative-usefulness-of-various-magnetic-resonance-sequences
#13
Deepakkumar Vinodary Mehta
INTRODUCTION: Spinal dysraphism occurs due to failure of fusion of parts along dorsal aspect of midline structures lying along spinal axis from skin to vertebrae and spinal cord. Congenital spinal anomalies may be minimal and asymptomatic like spinal bifida occulta, or severe with marked neurological deficits like Arnold-Chiari malformation or caudal regression syndrome. Magnetic Resonance Imaging (MRI) is the modality of choice to diagnose mild to severe spinal dysraphism. AIM: To diagnose type and extent of clinically suspected spinal anomalies by MRI scan and to compare various sequences for identifying neural tissue and fatty tissue in anomalies...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28963852/advanced-and-amplified-bold-fluctuations-in-high-grade-gliomas
#14
Lalit Gupta, Rakesh K Gupta, Alida A Postma, Prativa Sahoo, Pradeep K Gupta, Rana Patir, Sunita Ahlawat, Indrajit Saha, Walter H Backes
BACKGROUND: Glioma grade along with patient's age and general health are used for treatment planning and prognosis. PURPOSE: To characterize and quantify the spontaneous blood oxygen level-dependent (BOLD) fluctuations in gliomas using measures based on T2*-weighted signal time-series and to distinguish between high- and low-grade gliomas. STUDY TYPE: Retrospective. SUBJECTS: Twenty-one patients with high-grade and 13 patients with low-grade gliomas confirmed on histology were investigated...
September 30, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28957072/mixture-fraction-imaging-at-1%C3%A2-%C3%A2-khz-using-femtosecond-laser-induced-fluorescence-of-krypton
#15
Daniel R Richardson, Naibo Jiang, Hans U Stauffer, Sean P Kearney, Sukesh Roy, James R Gord
Femtosecond, two-photon-absorption laser-induced-fluorescence (TALIF) imaging measurements of krypton (Kr) are demonstrated to study mixing in gaseous flows. A measurement approach is presented in which observed Kr TALIF signals are 7 times stronger than the current state-of-the-art methodology. Fluorescence emission is compared for different gas pressures and excitation wavelengths, and the strongest fluorescence signals were observed when the excitation wavelength was tuned to 212.56 nm. Using this optimized excitation scheme, 1-kHz, single-laser-shot visualizations of unsteady flows and two-dimensional measurements of mixture fraction and scalar dissipation rate of a Kr-seeded jet are demonstrated...
September 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28953450/enhanced-immune-response-to-rabies-viruses-by-the-use-of-a-liposome-adjuvant-in-vaccines
#16
Li Miao, Yi Yang, Mingkun Yan, Yanchun Li, Jieshu Zhao, Jieshi Guo, Dong Zheng
Essen regimen, the Thai Red Cross two-site ID regimen, Zagreb schedule, and the eight-site ID regimen are the standard rabies vaccines recommended by the World Health Organization (WHO). In this study, a liposomal rabies vaccine (LipoRV) was developed, which was found to facilitate the production of rabies virus neutralizing antibody (RVNA) in BALB/c mice. Liposome solution was prepared with hydrogenated soya phosphatide and cholesterol. LipoRV composed of liposome solution and inactivated rabies vaccine (IRV)...
September 27, 2017: Viral Immunology
https://www.readbyqxmd.com/read/28951724/prior-mental-fatigue-impairs-marksmanship-decision-performance
#17
James Head, Matthew S Tenan, Andrew J Tweedell, Michael E LaFiandra, Frank Morelli, Kyle M Wilson, Samson V Ortega, William S Helton
Purpose: Mental fatigue has been shown to impair subsequent physical performance in continuous and discontinuous exercise. However, its influence on subsequent fine-motor performance in an applied setting (e.g., marksmanship for trained soldiers) is relatively unknown. The purpose of this study was to investigate whether prior mental fatigue influences subsequent marksmanship performance as measured by shooting accuracy and judgment of soldiers in a live-fire scenario. Methods: Twenty trained infantry soldiers engaged targets after completing either a mental fatigue or control intervention in a repeated measure design...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28949165/measured-emittance-dependence-on-the-injection-method-in-laser-plasma-accelerators
#18
S K Barber, J van Tilborg, C B Schroeder, R Lehe, H-E Tsai, K K Swanson, S Steinke, K Nakamura, C G R Geddes, C Benedetti, E Esarey, W P Leemans
Single-shot, charge-dependent emittance measurements of electron beams generated by a laser plasma accelerator (LPA) reveal that shock-induced density down-ramp injection produces beams with normalized emittances a factor of 2 smaller than beams produced via ionization injection. Such a comparison is made possible by the tunable LPA setup, which allows electron beams with nearly identical central energy and peak spectral charge density to be produced using the two distinct injection mechanisms. Parametric measurements of this type are essential for the development of LPA-based applications which ultimately require high charge density and low emittance...
September 8, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28940621/characterization-of-the-diffusion-coefficient-of-blood
#19
Carsten Funck, Frederik Bernd Laun, Andreas Wetscherek
PURPOSE: To characterize the diffusion coefficient of human blood for accurate results in intravoxel incoherent motion imaging. METHODS: Diffusion-weighted MRI of blood samples from 10 healthy volunteers was acquired with a single-shot echo-planar-imaging sequence at body temperature. Effects of gradient profile (monopolar or flow-compensated), diffusion time (40-100 ms), and echo time (60-200 ms) were investigated. RESULTS: Although measured apparent diffusion coefficients of blood were larger for flow-compensated than for monopolar gradients, no dependence of the apparent diffusion coefficient on the diffusion time was found...
September 23, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28939903/determination-of-extracellular-matrix-collagen-fibril-architectures-and-pathological-remodeling-by-polarization-dependent-second-harmonic-microscopy
#20
Denis Rouède, Emmanuel Schaub, Jean-Jacques Bellanger, Frédéric Ezan, Jean-Claude Scimeca, Georges Baffet, François Tiaho
Polarization dependence second harmonic generation (P-SHG) microscopy is gaining increase popularity for in situ quantification of fibrillar protein architectures. In this report, we combine P-SHG microscopy, new linear least square (LLS) fitting and modeling to determine and convert the complex second-order non-linear optical anisotropy parameter ρ of several collagen rich tissues into a simple geometric organization of collagen fibrils. Modeling integrates a priori knowledge of polyhelical organization of collagen molecule polymers forming fibrils and bundles of fibrils as well as Poisson photonic shot noise of the detection system...
September 22, 2017: Scientific Reports
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