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https://www.readbyqxmd.com/read/28214938/baseline-trace-metals-in-patella-caerulea-in-a-central-tyrrhenian-ecosystem-pontine-islands-archipelago-and-lazio-region-coastal-sites-italy
#1
Marcelo Enrique Conti, Giustino Mele, Maria Grazia Finoia
In this study, we tested the aptitude of the gastropod mollusk Patella caerulea as biomonitor of elemental pollution in seawater of a central Tyrrhenian ecosystem (Pontine Islands archipelago and Lazio region coastal sites, Italy). Concentrations of Cd, Cr, Cu, Ni, Pb, and Zn were measured in 120 individuals collected in six strategic locations in two sampling campaigns during 2011 and 2012. Samples of surrounding seawater were also collected in the same sites and tested for the same metals in order to obtain the respective concentration factors (CFs)...
February 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28210486/touch-accelerates-visual-awareness
#2
Claudia Lunghi, Luca Lo Verde, David Alais
To efficiently interact with the external environment, our nervous system combines information arising from different sensory modalities. Recent evidence suggests that cross-modal interactions can be automatic and even unconscious, reflecting the ecological relevance of cross-modal processing. Here, we use continuous flash suppression (CFS) to directly investigate whether haptic signals can interact with visual signals outside of visual awareness. We measured suppression durations of visual gratings rendered invisible by CFS either during visual stimulation alone or during visuo-haptic stimulation...
January 2017: I-Perception
https://www.readbyqxmd.com/read/28204965/prognostic-value-of-simple-frailty-and-malnutrition-screening-tools-in-patients-with-acute-heart-failure-due-to-left-ventricular-systolic-dysfunction
#3
S Sze, J Zhang, P Pellicori, D Morgan, A Hoye, A L Clark
BACKGROUND: Frailty and malnutrition are common in patients with heart failure (HF), and are associated with adverse outcomes. We studied the prognostic value of three malnutrition and three frailty indices in patients admitted acutely to hospital with HF. METHODS: 265 consecutive patients [62% males, median age 80 (interquartile range (IQR): 72-86) years, median NTproBNP 3633 (IQR: 2025-6407) ng/l] admitted with HF between 2013 and 2014 were enrolled. Patients were screened for frailty using the Derby frailty index (DFI), acute frailty network (AFN) frailty criteria, and clinical frailty scale (CFS) and for malnutrition using the geriatric nutritional risk index (GNRI), controlling nutritional status (CONUT) score and prognostic nutritional index (PNI)...
February 15, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28202772/high-throughput-screening-of-tyrosine-kinase-inhibitor-cardiotoxicity-with-human-induced-pluripotent-stem-cells
#4
Arun Sharma, Paul W Burridge, Wesley L McKeithan, Ricardo Serrano, Praveen Shukla, Nazish Sayed, Jared M Churko, Tomoya Kitani, Haodi Wu, Alexandra Holmström, Elena Matsa, Yuan Zhang, Anusha Kumar, Alice C Fan, Juan C Del Álamo, Sean M Wu, Javid J Moslehi, Mark Mercola, Joseph C Wu
Tyrosine kinase inhibitors (TKIs), despite their efficacy as anticancer therapeutics, are associated with cardiovascular side effects ranging from induced arrhythmias to heart failure. We used human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), generated from 11 healthy individuals and 2 patients receiving cancer treatment, to screen U.S. Food and Drug Administration-approved TKIs for cardiotoxicities by measuring alterations in cardiomyocyte viability, contractility, electrophysiology, calcium handling, and signaling...
February 15, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28196533/assessment-of-complementary-feeding-of-canadian-infants-effects-on-microbiome-oxidative-stress-a-randomized-controlled-trial
#5
Wafaa Qasem, Meghan B Azad, Zakir Hossain, Elnaz Azad, Sarah Jorgensen, Sandra Castillo San Juan, Chenxi Cai, Ehsan Khafipour, Trust Beta, L Jackson Roberts, James Friel
BACKGROUND: The World Health Organization recommends exclusive breastfeeding until 6 months followed by introduction of iron-rich complementary foods (CFs). The aim of this study was to determine the impact of different iron-rich CFs on infant gut inflammation and microbiota. METHODS: Eighty-seven exclusively breastfed infants were randomly assigned to receive one of the following as their first CF: iron-fortified cereal (Cer), iron-fortified cereal with fruit (Cer + Fr), or meat (M)...
February 14, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28190808/quantification-of-triacylglycerol-molecular-species-in-edible-fats-and-oils-by-gas-chromatographyflame-ionization-detector-using-correction-factors
#6
Kazuaki Yoshinaga, Junji Obi, Toshiharu Nagai, Hiroyuki Iioka, Akihiko Yoshida, Fumiaki Beppu, Naohiro Gotoh
In the present study, the resolution parameters and correction factors (CFs) of triacylglycerol (TAG) standards were estimated by gas chromatography-flame ionization detector (GC-FID) to achieve the precise quantification of the TAG composition in edible fats and oils. Forty seven TAG standards comprising capric acid, lauric acid, myristic acid, pentadecanoic acid, palmitic acid, palmitoleic acid, stearic acid, oleic acid, linoleic acid, and/or linolenic acid were analyzed, and the CFs of these TAGs were obtained against tripentadecanoyl glycerol as the internal standard...
February 10, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28186393/chronic-fatigue-in-ehlers-danlos-syndrome-hypermobile-type
#7
Alan Hakim, Inge De Wandele, Chris O'Callaghan, Alan Pocinki, Peter Rowe
Chronic fatigue is an important contributor to impaired health-related quality of life in Ehlers-Danlos syndrome. There is overlap in the symptoms and findings of EDS and chronic fatigue syndrome. A proportion of those with CFS likely have EDS that has not been identified. The evaluation of chronic fatigue in EDS needs to include a careful clinical examination and laboratory testing to exclude common causes of fatigue including anemia, hypothyroidisim, and chronic infection, as well as dysfunction of major physiological or organ systems...
February 10, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/28183406/long-term-economic-evaluation-of-cognitive-behavioural-group-treatment-versus-enhanced-usual-care-for-functional-somatic-syndromes
#8
Andreas Schröder, Eva Ørnbøl, Jens S Jensen, Michael Sharpe, Per Fink
OBJECTIVE: Patients with functional somatic syndromes (FSS) such as fibromyalgia and chronic fatigue syndrome have a poor outcome and can incur high healthcare and societal costs. We aimed to compare the medium-term (16months) cost-effectiveness and the long-term (40months) economic outcomes of a bespoke cognitive-behavioural group treatment (STreSS) with that of enhanced usual care (EUC). METHODS: We obtained complete data on healthcare and indirect costs (i.e...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28182802/the-association-of-geriatric-syndromes-with-hospital-outcomes
#9
Roman Romero-Ortuno, Duncan R Forsyth, Kathryn Jane Wilson, Ewen Cameron, Stephen Wallis, Richard Biram, Victoria Keevil
BACKGROUND: Frailty, history of dementia (HoD), and acute confusional states (ACS) are common in older patients admitted to hospital. OBJECTIVE: To study the association of frailty (≥6 points in the Clinical Frailty Scale [CFS]), HoD, and ACS with hospital outcomes, controlling for age, gender, acute illness severity (measured by a Modified Early Warning Score in the emergency department), comorbidity (Charlson Comorbidity Index), and discharging specialty (general medicine, geriatric medicine, surgery)...
February 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28181589/developmental-stage-dependent-effects-of-cardiac-fibroblasts-on-function-of-stem-cell-derived-engineered-cardiac-tissues
#10
Brian Liau, Christopher P Jackman, Yanzhen Li, Nenad Bursac
We investigated whether the developmental stage of mouse cardiac fibroblasts (CFs) influences the formation and function of engineered cardiac tissues made of mouse embryonic stem cell-derived cardiomyocytes (mESC-CMs). Engineered cardiac tissue patches were fabricated by encapsulating pure mESC-CMs, mESC-CMs + adult CFs, or mESC-CMs + fetal CFs in fibrin-based hydrogel. Tissue patches containing fetal CFs exhibited higher velocity of action potential propagation and contractile force amplitude compared to patches containing adult CFs, while pure mESC-CM patches did not form functional syncytium...
February 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28167198/analysis-of-serum-interleukin-27-and-interleukin-35-concentrations-in-patients-with-guillain-barr%C3%A3-syndrome
#11
Lin-Jie Zhang, Hui-Yue Guo, Da-Qi Zhang, Rong Wang, Ting Li, Li-Min Li, Dong-Mei Suo, Li Yang
BACKGROUNDS: Guillain-Barré syndrome (GBS) is a postinfectious immune-mediated peripheral neuropathy. Interleukin (IL)-27 and IL-35 have been recognized as novel members of IL-12 family. We evaluated the serum and cerebral spinal fluid (CFS) concentrations of IL-27 and IL-35 in GBS and analyze their correlations with clinical characteristics. METHODS: Serum samples from 50 patients with GBS including 9 acute inflammatory demyelinating polyradiculoneuropathy (AIDP), 33 acute motor axonal neuropathy (AMAN) and 8 unclassified and 35 age- and sex-matched healthy controls were collected...
February 4, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28162843/a-sociological-stance-on-fatigue-and-tiredness-social-inequalities-norms-and-representations
#12
Marc Loriol
Fatigue is complex, representing simultaneously a physiological, psychological and social phenomenon. The sociological approach attempts to understand the experience of fatigue and its characterization at diverse periods and in various social contexts. After giving a sociological history of different forms of fatigue through the ages (acedia, melancholy, neurasthenia, chronic fatigue syndrome, etc.), this article proposes a social epidemiology of fatigue in the current period. Objectification of working and living conditions allows us to illustrate social inequalities in fatigue and exhaustion, but seems to contradict dominant social representations of fatigue today...
February 2, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28162719/-470-effects-of-lidocaine-injections-on-overall-fatigue-in-patients-with-chronic-fatigue-syndrome
#13
R Staud, J Boissoneault, D Price, M Robinson
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162483/-254-altered-resting-state-functional-connectivity-is-correlated-with-fatigue-and-pain-in-patients-with-chronic-fatigue-syndrome
#14
J Boissoneault, J Letzen, A O'Shea, S Lai, M Robinson, R Staud
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28154488/antifungal-activity-of-lactic-acid-bacteria-strains-isolated-from-natural-honey-against-pathogenic-candida-species
#15
Bulgasem Y Bulgasem, Mohd Nizam Lani, Zaiton Hassan, Wan Mohtar Wan Yusoff, Sumaya G Fnaish
The role of lactic acid bacteria (LAB) in honey as antifungal activity has received little attention and their mechanism of inhibitory of fungi is not fully understood. In this study, LAB were isolated from honey samples from Malaysia, Libya, Saudi Arabia, and Yemen. Twenty-five isolates were confirmed LAB by catalase test and Gram staining, and were screened for antifungal activity. Four LAB showed inhibitory activity against Candida spp. using the dual agar overlay method. And they were identified as Lactobacillus plantarum HS isolated from Al-Seder honey, Lactobacillus curvatus HH isolated from Al-Hanon honey, Pediococcus acidilactici HC isolated from Tualang honey and Pediococcus pentosaceus HM isolated from Al-Maray honey by the 16S rDNA sequence...
December 2016: Mycobiology
https://www.readbyqxmd.com/read/28150361/cornea-and-its-adaptation-to-environment-and-accommodation-function-in-veiled-chameleon-chamaeleo-calyptratus-ultrastructure-and-3d-transmission-electron-tomography
#16
Saeed Akhtar, Adnan A Khan, Hussain A Albuhayzah, Turki M Almubrad
We investigate the ultrastructural features and 3D electron tomography of chameleon (Chamaeleon calyptratus) which is a native of desert environments of Saudi Arabia. The corneas of the chameleon were fixed in 2.5% glutaraldehyde containing cuprolinic blue in sodium acetate buffer for electron microscopy and tomography, and observed under a JEOL 1400 transmission electron microscope. The thin cornea (21.92 μm) contained 28-30 collagen fibril lamellae. The middle stromal lamellae (from 13 to 19) contained keratocytes with a long cell process and filled with granular material...
February 1, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28149698/causal-events-enter-awareness-faster-than-non-causal-events
#17
Pieter Moors, Johan Wagemans, Lee de-Wit
Philosophers have long argued that causality cannot be directly observed but requires a conscious inference (Hume, 1967). Albert Michotte however developed numerous visual phenomena in which people seemed to perceive causality akin to primary visual properties like colour or motion (Michotte, 1946). Michotte claimed that the perception of causality did not require a conscious, deliberate inference but, working over 70 years ago, he did not have access to the experimental methods to test this claim. Here we employ Continuous Flash Suppression (CFS)-an interocular suppression technique to render stimuli invisible (Tsuchiya & Koch, 2005)-to test whether causal events enter awareness faster than non-causal events...
2017: PeerJ
https://www.readbyqxmd.com/read/28149288/attention-orienting-in-response-to-non-conscious-hierarchical-arrows-individuals-with-higher-autistic-traits-differ-in-their-global-local-bias
#18
Robin Laycock, Daniel Chan, Sheila G Crewther
One aspect of the social communication impairments that characterize autism spectrum disorder (ASD) include reduced use of often subtle non-verbal social cues. People with ASD, and those with self-reported sub-threshold autistic traits, also show impairments in rapid visual processing of stimuli unrelated to social or emotional properties. Hence, this study sought to investigate whether perceptually non-conscious visual processing is related to autistic traits. A neurotypical sample of thirty young adults completed the Subthreshold Autism Trait Questionnaire and a Posner-like attention cueing task...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28144676/thin-tiox-layer-as-a-voltage-divider-layer-located-at-the-quasi-ohmic-junction-in-the-pt-ta2o5-ta-resistance-switching-memory
#19
Xiang Yuan Li, Xing Long Shao, Yi Chuan Wang, Hao Jiang, Cheol Seong Hwang, Jin Shi Zhao
Ta2O5 has been an appealing contender for the resistance switching random access memory (ReRAM). The resistance switching (RS) in this material is induced by the repeated formation and rupture of the conducting filaments (CFs) in the oxide layer, which are accompanied by the almost inevitable randomness of the switching parameters. In this work, a 1 to 2 nm-thick Ti layer was deposited on the 10 nm-thick Ta2O5 RS layer, which greatly improved the RS performances, including the much-improved switching uniformity...
February 1, 2017: Nanoscale
https://www.readbyqxmd.com/read/28143516/important-factors-to-consider-when-treating-children-with-chronic-fatigue-syndrome-myalgic-encephalomyelitis-cfs-me-perspectives-of-health-professionals-from-specialist-services
#20
Roxanne M Parslow, Alison Shaw, Kirstie L Haywood, Esther Crawley
BACKGROUND: Paediatric Chronic Fatigue Syndrome (CFS)/Myalgic Encephalomyelitis (ME) is relatively common and disabling. Improving treatment requires the development of Patient Reported Outcome Measures (PROMs) that enable clinicians and researchers to collect patient-centred evidence on outcomes. Health professionals are well placed to provide clinical insight into the condition, its treatment and possible outcomes. This study aimed to understand the perspectives of specialist paediatric CFS/ME health professionals and identify outcomes that are clinically important...
February 1, 2017: BMC Pediatrics
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