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https://www.readbyqxmd.com/read/28444396/circadian-impairment-of-distal-skin-temperature-rhythm-in-patients-with-sleep-disordered-breathing-the-effect-of-cpap
#1
Antonio Martinez-Nicolas, Marc Guaita, Joan Santamaría, Josep M Montserrat, María Ángeles Rol, Juan Antonio Madrid
Study objectives: Our aim was to evaluate the circadian rhythm of distal skin temperature (DST) in Sleep Disordered Breathing (SDB), its relation to excessive daytime sleepiness and the effect of continuous positive airway pressure (CPAP) on DST. Methods: Eighty SDB patients (53.1±1.2 years old, 27.6% women) and 67 healthy subjects (52.3±1.6 years old, 26.9% women) wore a temperature data logger for one week. On the last day of that week, SDB patients underwent a polysomnography followed by a Maintenance of Wakefulness Test (MWT), Multiple Sleep Latency Test (MSLT) and Sustained Attention to Response Task (SART) protocol to objectively quantify daytime sleepiness...
April 22, 2017: Sleep
https://www.readbyqxmd.com/read/28425965/comparison-of-cpap-and-hfnc-in-management-of-bronchiolitis-in-infants-and-young-children
#2
Majken Bisgaard Pedersen, Signe Vahlkvist
Continuous positive airway pressure (CPAP) has been used in infants with bronchiolitis for decades. Recently, high flow nasal cannula (HFNC) therapy was introduced We conducted a retrospective study of treatment with CPAP vs. HFNC between 2013 and 2015, comparing the development in respiratory rate, fraction of inspired oxygen (FiO2) and heart rate, treatment failure, duration of treatment, and length of hospital stay. A sample size of 49 children were included. Median age was 1.9 months. Median baseline pCO₂ was 7...
April 20, 2017: Children
https://www.readbyqxmd.com/read/28419387/effect-of-continuous-positive-airway-pressure-treatment-on-health-related-quality-of-life-and-sleepiness-in-high-cardiovascular-risk-individuals-with-sleep-apnea-best-apnea-interventions-for-research-bestair-trial
#3
Ying Y Zhao, Rui Wang, Kevin J Gleason, Eldrin F Lewis, Stuart F Quan, Claudia M Toth, Michael Morrical, Michael Rueschman, Jia Weng, James H Ware, Murray A Mittleman, Susan Redline
Study Objectives: The long term effect of continuous positive airway pressure (CPAP) on health-related quality of life (HRQOL) in patients with high cardiovascular disease risk and obstructive sleep apnea (OSA) without severe sleepiness is uncertain. We aimed to determine the effect of CPAP treatment on HRQOL in individuals with moderate or severe OSA and cardiovascular disease (CVD) or multiple CVD risk factors without severe sleepiness. Methods: In this randomized, controlled, parallel group study, 169 participants were assigned to treatment with CPAP or the control group (conservative medical therapy [CMT] or CMT with sham CPAP)...
April 17, 2017: Sleep
https://www.readbyqxmd.com/read/28419320/therapeutic-cpap-level-predicts-upper-airway-collapsibility-in-patients-with-obstructive-sleep-apnea-therapeutic-cpap-predicts-upper-airway-collapsibility
#4
Shane A Landry, Simon A Joosten, Danny J Eckert, Amy S Jordan, Scott A Sands, David P White, Atul Malhotra, Andrew Wellman, Garun S Hamilton, Bradley A Edwards
Study Objectives: Upper airway collapsibility is a key determinant of obstructive sleep apnea (OSA) which can influence the efficacy of certain non-CPAP treatment for OSA. However, there is no simple way to measure this variable clinically. The present study aimed to develop a clinically implementable tool to evaluate the collapsibility of a patient's upper airway. Methods: Collapsibility, as characterized by the passive pharyngeal critical closing pressure (Pcrit), was measured in 46 patients with OSA...
April 13, 2017: Sleep
https://www.readbyqxmd.com/read/28417254/whom-are-we-treating-with-adaptive-servo-ventilation-a-clinical-post-hoc-analysis
#5
Maximilian V Malfertheiner, C Lerzer, L Kolb, K Heider, F Zeman, F Gfüllner, L S Maier, M Pfeifer, M Arzt
BACKGROUND: Recent evidence has shown that adaptive servo-ventilation (ASV) is contraindicated in patients with predominant central sleep apnea (CSA) and reduced left ventricular ejection fraction (LVEF ≤45%). The objective of this study was to assess the clinical usage of ASV in patients at the time-point of the release of a safety warning by type of SDB, breathing pattern and LVEF. METHODS: Patients of a cardiac and a respirology sleep center, both in Germany, who received ASV therapy were contacted between May and October 2015...
April 17, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28416044/treatment-of-ptsd-related-osa-with-cpap-is-associated-with-only-a-modest-improvement-in-ptsd-possible-adjunctive-treatment-with-mood-stabilizers
#6
Madhulika A Gupta
No abstract text is available yet for this article.
April 12, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28409851/response-to-a-combination-of-oxygen-and-a-hypnotic-as-treatment-for-obstructive-sleep-apnoea-is-predicted-by-a-patient-s-therapeutic-cpap-requirement
#7
Shane A Landry, Simon A Joosten, Scott A Sands, David P White, Atul Malhotra, Andrew Wellman, Garun S Hamilton, Bradley A Edwards
BACKGROUND AND OBJECTIVE: Upper airway collapsibility predicts the response to several non-continuous positive airway pressure (CPAP) interventions for obstructive sleep apnoea (OSA). Measures of upper airway collapsibility cannot be easily performed in a clinical context; however, a patient's therapeutic CPAP requirement may serve as a surrogate measure of collapsibility. The present work aimed to compare the predictive use of CPAP level with detailed physiological measures of collapsibility...
April 13, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28408103/effect-of-cpap-on-diastolic-function-in-coronary-artery-disease-patients-with-nonsleepy-obstructive-sleep-apnea-a-randomized-controlled-trial
#8
Helena Glantz, Magnus C Johansson, Erik Thunström, Cecilia Wallentin Guron, Harun Uzel, Mustafa Saygin, Johan Herlitz, Yüksel Peker
BACKGROUND: Obstructive sleep apnea (OSA) has been associated with worse diastolic function in patients with coronary artery disease (CAD). This analysis determined whether continuous positive airway pressure (CPAP) treatment would improve diastolic function in CAD patients with nonsleepy OSA. METHODS: Between December 2005 and November 2010, 244 revascularized CAD patients with nonsleepy OSA (apnea-hypopnea index (AHI) ≥15/h, Epworth Sleepiness Scale [ESS] score<10) were randomly assigned to CPAP or no-CPAP...
March 25, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28399379/physiology-of-arousal-in-osa-and-potential-impacts-for-sedative-treatment
#9
Amy S Jordan, Fergal J O'Donoghue, Jennifer M Cori, John Trinder
Treatment options for patients with obstructive sleep apnea (OSA) intolerant of continuous positive airway pressure (CPAP) are limited. Thus, new therapies are sought. Recently, there has been interest in using sedatives to delay arousal from sleep, allowing upper airway dilator muscle recruitment sufficient to re-open the airway while maintaining sleep. In this review the rationale for sedative use and prior sedative studies in OSA are presented, along with a description of six factors that may determine sedative treatment success...
April 11, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28398157/effects-of-continuous-positive-airway-pressure-on-fatigue-in-two-patients-with-obstructive-sleep-apnea-presenting-with-chronic-fatigue-case-report-and-lessons-learned-from-a-failed-trial
#10
Els Tobback, Liesbeth Delesie, Ignace Hanoulle, Dirk Vogelaers, Dirk Pevernagie, An Mariman
INTRODUCTION: Patients referred to tertiary care for multidisciplinary investigation of unexplained chronic fatigue are not seldom diagnosed with obstructive sleep apnoea (OSA). As standard treatment for OSA, continuous positive airway pressure (CPAP) has been shown to decrease daytime sleepiness in OSA patients. However, the effect on fatigue as major complaint in chronic fatigue patients without excessive daytime sleepiness, is not fully understood nor explored. CASE REPORT: A prospective cross-over trial using effective and sham CPAP treatment periods in patients with unexplained chronic fatigue and OSA was interrupted because of poor recruitment and retainment due to complex design issues...
April 11, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28386781/diagnosing-and-managing-sleep-apnea-in-patients-with-chronic-cerebrovascular-disease-a-randomized-trial-of-a-home-based-strategy
#11
Dawn M Bravata, Vincent McClain, Charles Austin, Jared Ferguson, Nicholas Burrus, Edward J Miech, Marianne S Matthias, Neale Chumbler, Susan Ofner, Brian Foresman, Jason Sico, Carlos A Vaz Fragoso, Linda S Williams, Rajiv Agarwal, John Concato, H Klar Yaggi
BACKGROUND: Obstructive sleep apnea is common and associated with poor outcomes after stroke or transient ischemic attack (TIA). We sought to determine whether the intervention strategy improved sleep apnea detection, obstructive sleep apnea (OSA) treatment, and hypertension control among patients with chronic cerebrovascular disease and hypertension. METHODS: In this randomized controlled strategy trial intervention, patients received unattended polysomnography at baseline, and patients with OSA (apnea-hypopnea index ≥5 events/h) received auto-titrating continuous positive airway pressure (CPAP) for up to 1 year...
April 6, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28374832/a-randomized-controlled-trial-of-an-ambulatory-approach-versus-the-hospital-based-approach-in-managing-suspected-obstructive-sleep-apnea-syndrome
#12
David S Hui, Susanna S Ng, Kin-Wang To, Fanny W Ko, Jenny Ngai, Ken K P Chan, Wing-Ho Yip, Tat-On Chan, Karen Yiu, Wilson W S Tam
Comparisons of home-based versus hospital-based approach in managing patients with suspected obstructive sleep apnoea syndrome(OSAS). A prospective, controlled CPAP parallel study of new referrals with suspected OSAS randomized into group A) home-based or B) hospital-based approach. Following detection of AHI ≥ 15/hr by Embletta sleep study (group A) or polysomnography (group B), patients received CPAP for 3 months after an overnight autoCPAP titration at home or in hospital respectively. Modified intention-to-treat analysis of those with AHI ≥ 15/hr on CPAP (n = 86 vs 86) showed no difference in Epworth sleepiness score, the primary endpoint, but greater improvement in Sleep-Apnoea-Quality-of-Life-Index[difference 0...
April 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28374233/neurological-deficits-in-obstructive-sleep-apnea
#13
REVIEW
Luigi Ferini-Strambi, Giulia Elisabetta Lombardi, Sara Marelli, Andrea Galbiati
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder characterized by repetitive episodes of complete or partial obstruction of the upper airway. The prevalence of this disorder is strictly dependent on its gravity. At ≥15 events/h apnea-hypopnea index (AHI), it ranges from 6 to 17% in the general population, with higher rates in men and increasing with age. The hypoxia induced by OSA severely affects the structure and function of blood vessels, culminating in mortality and morbidity...
April 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28366323/effect-of-continuous-positive-airway-pressure-on-regional-cerebral-blood-flow-in-patients-with-severe-obstructive-sleep-apnea-syndrome
#14
Jeong Sik Kim, Ji Hye Seo, Mi-Ri Kang, Min Jae Seong, Won Gu Lee, Eun Yeon Joo, Seung Bong Hong
OBJECTIVES: Obstructive sleep apnea (OSA) is commonly associated with neural and cognitive deficits induced by recurrent hypoxemia and sleep fragment. The aims of this study were to use statistical parametric mapping (SPM) to analyze changes in regional cerebral blood flow (rCBF) in untreated patients with severe OSA before and after nasal continuous positive airway pressure (CPAP) treatment, examine the impact of OSA-related variables on rCBF, and assess the therapeutic effect of nasal CPAP treatment...
April 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28356182/the-efficacy-of-low-level-continuous-positive-airway-pressure-for-the-treatment-of-snoring
#15
Michelle A Guzman, Francis P Sgambati, Huy Pho, Rafael S Arias, Erin M Hawks, Erica M Wolfe, Tamás Ötvös, Russell Rosenberg, Riad Dakheel, Hartmut Schneider, Jason P Kirkness, Philip L Smith, Alan R Schwartz
STUDY OBJECTIVES: To assess effects of low-level continuous positive airway pressure (CPAP) on snoring in habitual snorers without obstructive sleep apnea (OSA). METHODS: A multicenter prospective in-laboratory reversal crossover intervention trial was conducted between September 2013 and August 2014. Habitual snorers were included if they snored (inspiratory sound pressure level ≥ 40 dBA) for ≥ 30% all sleep breaths on a baseline sleep study (Night 1), and if significant OSA and daytime somnolence were absent...
February 19, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28356178/autotitrating-cpap-as-a-tool-for-cpap-initiation-for-children
#16
Rebecca Mihai, Moya Vandeleur, Sally Pecoraro, Margot J Davey, Gillian M Nixon
STUDY OBJECTIVES: Few studies have assessed autotitrating positive airway pressure (autoPAP) for treatment of obstructive sleep apnea (OSA) in children. We aimed to review our use of autoPAP for initiation of continuous positive airway pressure (CPAP) therapy in children, and compare autoPAP-derived treatment pressures to CPAP treatment pressure determined by attended polysomnography (PSG). METHODS: Retrospective review of children initiated on autoPAP from 2013 to 2015...
February 20, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28356173/management-of-obstructive-sleep-apnea-in-commercial-motor-vehicle-operators-recommendations-of-the-aasm-sleep-and-transportation-safety-awareness-task-force
#17
Indira Gurubhagavatula, Shannon Sullivan, Amy Meoli, Susheel Patil, Ryan Olson, Michael Berneking, Nathaniel F Watson
The American Academy of Sleep Medicine Sleep and Transportation Safety Awareness Task Force responded to the Federal Motor Carrier Safety Administration and Federal Railroad Administration Advance Notice of Proposed Rulemaking and request for public comments regarding the evaluation of safety-sensitive personnel for moderate-to-severe obstructive sleep apnea (OSA). The following document represents this response. The most salient points provided in our comments are that (1) moderate-to-severe OSA is common among commercial motor vehicle operators (CMVOs) and contributes to an increased risk of crashes; (2) objective screening methods are available and preferred for identifying at-risk drivers, with the most commonly used indicator being body mass index; (3) treatment in the form of continuous positive airway pressure (CPAP) is effective and reduces crashes; (4) CPAP is economically viable; (5) guidelines are available to assist medical examiners in determining whether CMVOs with moderate-to-severe OSA should continue to work without restrictions, with conditional certification, or be disqualified from operating commercial motor vehicles...
March 28, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28356131/treatment-of-infants-with-syndromic-robin-sequence-with-modified-palatal-plates-a-minimally-invasive-treatment-option
#18
Silvia Müller-Hagedorn, Wolfgang Buchenau, Jörg Arand, Margit Bacher, Christian F Poets
BACKGROUND: Infants with Robin sequence (RS) suffer from upper airway obstruction (UAO) and feeding problems. We developed an oral appliance with a velar extension in combination with functional treatment and appropriate feeding techniques, which was proven effective in isolated RS. As the above problems are particularly challenging in syndromic RS, we set out to evaluate our treatment concept also in these patients. METHODS: We searched our electronic departmental database to identify all children admitted to our department between 01/01/2003 and 31/12/2009 because of syndromic RS...
March 30, 2017: Head & Face Medicine
https://www.readbyqxmd.com/read/28355752/-incidence-and-influencing-factors-of-continuous-positive-airway-pressure-treatment-emergent-central-sleep-apnea-in-the-patients-with-obstructive-sleep-apnea-syndrome-at-high-altitude
#19
Z B Miao, Y Y Wang, R Sun, H L Lei, D J Huang, L H Huang, C Y Fan, Y H Lü
Objective: To investigate the incidence of treatment-emergent central sleep apnea (TE-CSA), the characteristics of demography and the influencing factors in patients with obstructive sleep apnea syndrome (OSAS) after initial continuous positive airway pressure (CPAP) titration at high altitude. Methods: Clinical data of 297 patients with OSAS which living in plateau areas (1 000 meters or more above sea level) were retrospectively analyzed in this study from January to December, 2015. All of these patients taken an overnight CPAP titration in the Sleep Medicine Center of First People's Hospital of Yunnan Province...
March 28, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28352476/cpap-treatment-adherence-in-women-with-obstructive-sleep-apnea
#20
E Libman, S Bailes, C S Fichten, D Rizzo, L Creti, M Baltzan, R Grad, A Pavilanis, D-L Tran, K Conrod, R Amsel
Untreated obstructive sleep apnea (OSA) has numerous negative health-related consequences. Continuous positive airway pressure (CPAP) is generally considered the treatment of choice for OSA, but rates of nonadherence are high. It is believed that OSA is more prevalent among men; therefore understanding how OSA presents among women is limited and treatment adherence has received little research attention. For this study, 29 women were recruited from primary care offices. They completed a questionnaire battery and underwent a night of nocturnal polysomnography (PSG) followed by a visit with a sleep specialist...
2017: Sleep Disorders
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