keyword
https://read.qxmd.com/read/37312422/comparing-outcomes-of-laser-hemorrhoidoplasty-and-ligasure-hemorrhoidectomy-in-grade-ii-iii-hemorrhoidal-disease-a-retrospective-analysis
#1
JOURNAL ARTICLE
Haluk Tümer, Mevlüt Harun Ağca
BACKGROUND: Hemorrhoidal disease is a common ailment that presents a challenge in terms of standard treatment methods. Although surgical hemorrhoidectomy is often considered the gold standard, new surgical techniques have emerged, such as laser hemorrhoidoplasty and LigaSure hemorrhoidectomy, to address postoperative pain, bleeding, and extended return-to-work times. This study aims to compare the outcomes of laser hemorrhoidoplasty and LigaSure hemorrhoidectomy in patients with grade II-III hemorrhoidal disease...
2023: ANZ Journal of Surgery
https://read.qxmd.com/read/37153265/a-comparison-of-laser-and-fistulotomy-techniques-in-the-treatment-of-fistula-in-ano
#2
JOURNAL ARTICLE
Haluk Tümer, Guney Cem Bulbuloglu
Background Anal fistulas are a common complication of perianal abscesses. The treatment of anal fistulas is challenging, with persistent and high recurrence rates. The aim of this study was to evaluate the efficacy and cost-effectiveness of laser ablation compared to fistulotomy in the treatment of anal fistulas. Materials and methods The patients were examined for external and internal openings of the fistula, its number, length, type, relationship with the sphincters, and any previous history of abscess or proctological surgery...
April 2023: Curēus
https://read.qxmd.com/read/36918123/evaluation-of-the-effects-of-arthrocentesis-combined-with-occlusal-stabilization-splint-on-disc-displacement-without-reduction-induced-acute-and-closed-lock-a-prospective-cohort-study
#3
JOURNAL ARTICLE
Aras Erdil, Mustafa Sami Demirsoy, Mehmet Kemal Tümer
OBJECTIVE: Disc displacement without reduction (DDWoR) of the temporomandibular joint is associated with limited mouth opening and arthralgia. In the natural course of the disorder, there is a tendency to progress to degenerative joint diseases. First-line treatment aims to reduce pain and restore joint function. The current study aims to examine the efficacy of an occlusal stabilization splint applied simultaneously with arthrocentesis as first-line treatment in acute and chronic closed-locks...
March 12, 2023: Journal of Stomatology, Oral and Maxillofacial Surgery
https://read.qxmd.com/read/36410683/a-possibly-new-autoinflammatory-disease-due-to-compound-heterozygous-phosphomevalonate-kinase-gene-mutation-does-it-open-a-new-horizon
#4
Çisem Yildiz, Deniz Gezgin Yildirim, Asli Inci, Leyla Tümer, Filiz Başak Cengiz Ergin, Emine Nur Sunar Yayla, Pelin Esmeray Şenol, Nihal Karaçayir, Ödül Eğritaş Gürkan, Ilyas Okur, Fatih S Ezgü, Sevcan A Bakkaloğlu
BACKGROUND: Mevalonate kinase (MVK) plays a role in cholesterol and non-sterol isoprenoid biosynthesis and its deficiency-related diseases are caused by bi-allelic pathogenic mutations in the MVK gene, (MVK), which leads to rare hereditary autoinflammatory diseases. The disease may manifest different clinical phenotypes depending on the degree of the deficiency in the enzyme activity. The complete deficiency of the enzyme activity results in the severe metabolic disease called mevalonic aciduria, while a partial deficiency results in a broad spectrum of clinical presentations called hyper-immunoglobulin D syndrome (HIDS)...
November 18, 2022: Joint, Bone, Spine: Revue du Rhumatisme
https://read.qxmd.com/read/35098403/clinical-and-molecular-evaluation-of-mefv-gene-variants-in-the-turkish-population-a-study-by-the-national-genetics-consortium
#5
JOURNAL ARTICLE
Munis Dundar, Umut Fahrioglu, Saliha Handan Yildiz, Burcu Bakir-Gungor, Sehime Gulsun Temel, Haluk Akin, Sevilhan Artan, Tulin Cora, Feride Iffet Sahin, Ahmet Dursun, Ozlem Sezer, Hakan Gurkan, Murat Erdogan, C Nur Semerci Gunduz, Atil Bisgin, Ozturk Ozdemir, Ayfer Ulgenalp, E Ferda Percin, Malik Ejder Yildirim, Selahaddin Tekes, Haydar Bagis, Huseyin Yuce, Nilgun Duman, Gokay Bozkurt, Kanay Yararbas, Mahmut Selman Yildirim, Ahmet Arman, Ercan Mihci, Serpil Eraslan, Zuhal Mert Altintas, Huri Sema Aymelek, Hatice Ilgin Ruhi, Abdulgani Tatar, Mahmut Cerkez Ergoren, G Ozan Cetin, Umut Altunoglu, Ahmet Okay Caglayan, Berrin Yuksel, Yusuf Ozkul, Cetin Saatci, Sercan Kenanoglu, Nilgun Karasu, Bilge Dundar, Firat Ozcelik, Mikail Demir, Betul Seyhan Siniksaran, Hande Kulak, Kubra Kiranatlioglu, Kubra Baysal, Ulviyya Kazimli, Hilal Akalin, Ayca Dundar, Mehmet Boz, Arslan Bayram, Asli Subasioglu, Fatma Kurt Colak, Neslihan Karaduman, Meltem Cerrah Gunes, Nefise Kandemir, Busra Aynekin, Rabia Emekli, Izem Olcay Sahin, Sevda Yesim Ozdemir, Muge Gulcihan Onal, Abdurrahman Soner Senel, Muammer Hakan Poyrazoglu, Ayse Nur Pac Kisaarslan, Sebnem Gursoy, Mevlut Baskol, Mustafa Calis, Huseyin Demir, Gozde Erturk Zararsiz, Mujgan Ozdemir Erdogan, Muhsin Elmas, Mustafa Solak, Memnune Sena Ulu, Adam Thahir, Zafer Aydin, Umut Atasever, Sebnem Ozemri Sag, Lamiya Aliyeva, Adem Alemdar, Berkcan Dogan, Cemre Ornek Erguzeloglu, Niyazi Kaya, Ferda Ozkinay, Ozgur Cogulu, Asude Durmaz, Huseyin Onay, Emin Karaca, Burak Durmaz, Ayca Aykut, Oguz Cilingir, Beyhan Durak Aras, Ebru Erzurumluoglu Gokalp, Serap Arslan, Arda Temena, Konul Haziyeva, Sinem Kocagil, Hasan Bas, Ezgi Susam, Ali Riza Keklikci, Elif Sarac, Nadir Kocak, Suleyman Nergiz, Yunus Kasim Terzi, Selin Akad Dincer, Esra Sidika Baskin, Gunes Cakmak Genc, Oguzhan Bahadir, Aslihan Sanri, Serbulent Yigit, Hilmi Tozkir, Sinem Yalcintepe, Nese Ozkayin, Aslihan Kiraz, Burhan Balta, Gizem Akinci Gonen, E Emre Kurt, Gulay Gulec Ceylan, Ahmet Cevdet Ceylan, Sukran Erten, Sevcan Tug Bozdogan, Ibrahim Boga, Mustafa Yilmaz, Fatma Silan, Mehmet Kocabey, Altug Koc, Tufan Cankaya, Elcin Bora, Ozlem Giray Bozkaya, Derya Ercal, Mehmet Ali Ergun, Sezen Guntekin Ergun, Yesim Sidar Duman, Serife Busra Beyazit, Veysiye Hulya Uzel, Serda Em, Muhammer Ozgur Cevik, Recep Eroz, Mercan Demirtas, Cem Koray Firat, Zehra Manav Kabayegit, Mustafa Altan, Lamiya Mardan, Ceyhan Sayar, Sait Tumer, Burcu Turkgenc, Hilal Keskin Karakoyun, Betul Tunc, Seda Kuru, Aysegul Zamani, Bilgen Bilge Geckinli, Esra Arslan Ates, Ozden Altiok Clark, Asli Toylu, Mert Coskun, Banu Nur, Ilmay Bilge, Oya Uygur Bayramicli, Hakan Emmungil, Zeynep Komesli, Mujdat Zeybel, Figen Gurakan, Mehmet Tasdemir, Rejin Kebudi, Halil Gurhan Karabulut, Timur Tuncali, Nuket Yurur Kutlay, Cigdem Yuce Kahraman, Nerin Bahceciler Onder, Ilke Beyitler, Salih Kavukcu, Pinar Tulay, Ozgur Tosun, Gulten Tuncel, Gamze Mocan, Hamdi Kale, Zehra Oya Uyguner, Aynur Acar, Mert Altinay, Levent Erdem
Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disorder with recurrent fever, abdominal pain, serositis, articular manifestations, erysipelas-like erythema, and renal complications as its main features. Caused by the mutations in the MEditerranean FeVer (MEFV) gene, it mainly affects people of Mediterranean descent with a higher incidence in the Turkish, Jewish, Arabic, and Armenian populations. As our understanding of FMF improves, it becomes clearer that we are facing with a more complex picture of FMF with respect to its pathogenesis, penetrance, variant type (gain-of-function vs...
June 2022: Functional & Integrative Genomics
https://read.qxmd.com/read/34990501/evaluation-of-the-efficacy-of-auriculotemporal-nerve-block-in-temporomandibular-disorders
#6
JOURNAL ARTICLE
Mustafa Sami Demirsoy, Aras Erdil, Mehmet Kemal Tümer
AIMS: To investigate the effectiveness of the auriculotemporal nerve block (ATNB) technique in conjunction with noninvasive therapies for the treatment of disc displacement with reduction (DDWR) or without reduction (DDWOR) in addition to arthralgia of the temporomandibular joint (TMJ). METHODS: The data of 22 patients diagnosed with DDWR and DDWOR whose clinical conditions did not improve despite noninvasive treatments were analyzed. ATNB was applied to each patient during the first visit and readministered at 1- and 4-week follow-up visits...
October 2021: Journal of Oral & Facial Pain and Headache
https://read.qxmd.com/read/34512863/-diplazium-esculentum-retz-sw-ethnomedicinal-phytochemical-and-pharmacological-overview-of-the-himalayan-ferns
#7
REVIEW
Prabhakar Semwal, Sakshi Painuli, Kartik M Painuli, Gizem Antika, Tugba Boyunegmez Tumer, Ashish Thapliyal, William N Setzer, Miquel Martorell, Mohammed M Alshehri, Yasaman Taheri, Sevgi Durna Daştan, Seyed Abdulmajid Ayatollahi, Anka Trajkovska Petkoska, Javad Sharifi-Rad, William C Cho
The genus Diplazium (family: Athyriaceae) comprises approximately 350 species of pteridophytes . Diplazium esculentum (Retz.) Sw. is an important member of this genus and commonly known as a wild vegetable in the Himalayan and sub-Himalayan communities. According to the literature analysis, D. esculentum was traditionally used for the prevention or treatment of several diseases such as diabetes, smallpox, asthma, diarrhea, rheumatism, dysentery, headache, fever, wounds, pain, measles, hypertension, constipation, oligospermia, bone fracture, and glandular swellings...
2021: Oxidative Medicine and Cellular Longevity
https://read.qxmd.com/read/34320713/dexketoprofen-vs-tamsulosin-vs-silodosin-vs-tadalafil-as-medical-expulsive-therapy-for-distal-ureteral-stones-in-men
#8
RANDOMIZED CONTROLLED TRIAL
Metin Gur, Muhammet Bahaettin Ulu, Suleyman Tumer Caliskan, Kemal Ozturk, Ekrem Akdeniz
OBJECTIVE: To assess the effectiveness of the use of dexketoprofen, tamsulosin, silodosin, and tadalafil in medical expulsive therapy for distal ureteral stones in male patients. STUDY DESIGN: Cohort study. PLACE AND DURATION OF STUDY: Department of Urology, Gazi Hospital, Samsun, Turkey, from March 2020 to March 2021. METHODOLOGY: Adult males satisfying the inclusion criteria were randomly assigned into dexketoprofen (Group 1), tamsulosin (Group 2), silodosin (Group 3), or tadalafil (Group 4) treatment arms...
August 2021: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://read.qxmd.com/read/33819418/familial-hyperphosphatemic-tumoral-calcinosis-in-an-unusual-and-usual-sites-and-dramatic-improvement-with-the-treatment-of-acetazolamide-sevelamer-and-topical-sodium-thiosulfate
#9
Merve Emecen Sanli, Ayse Kilic, Ekin Aktasoglu, Asli Inci, Ilyas Okur, Fatih Ezgu, Leyla Tumer
OBJECTIVES: Familial hyperphosphatemic tumoral calcinosis is a rare disorder characterized by hyperphosphatemia with recurrent ectopic periarticular calcifications, in addition to other visceral and vascular manifestations, without any inflammatory or neoplastic disorder. The available treatment strategies are limited. Here we report an eight year old female patient with recurrent lesions under the chin, and bilateral hips which are painful and improving of the size of the lesions and hyperphosphatemia...
June 25, 2021: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/33404770/hypophosphatasia-is-it-an-underdiagnosed-disease-even-by-expert-physicians
#10
JOURNAL ARTICLE
Aslı İnci, Filiz Başak Cengiz Ergin, Burcu Topcu Yüce, Bahattin Çiftçi, Ercan Demir, Necla Buyan, İlyas Okur, Gürsel Biberoğlu, Rıdvan Murat Öktem, Leyla Tümer, Fatih Süheyl Ezgü
INTRODUCTION: Hypophosphatasia (HPP) is caused by mutations in the ALPL that encodes the tissue-nonspecific isoenzyme of alkaline phosphatase (ALP). Clinical manifestations range from extreme life-threatening lethal forms to no signs or symptoms at all. MATERIALS AND METHODS: Consecutive 30,000 outpatients and inpatients with ALP data were screened retrospectively, out of which 1000 patients were found to have low levels of ALP more than once. Then, patients were evaluated for the symptoms and signs of HPP with further biochemical and genetic analyses...
July 2021: Journal of Bone and Mineral Metabolism
https://read.qxmd.com/read/33047698/evaluation-of-the-effects-of-the-surgical-removal-of-impacted-third-molars-on-the-emotional-state-of-individuals-with-beck-depression-inventory
#11
JOURNAL ARTICLE
M S Demirsoy, M K Tumer, A Erdil, Y Ozkan
Aims: In this study, using Beck depression inventory (BDI), we aimed to determine alterations in the emotional state of patients who had impacted third molars (M3) extracted owing to postoperative pain, edema, and trismus.In this prospective clinical trial, which was conducted at Tokat Gaziosmanpasa University, Faculty of Dentistry, Department of Maxillofacial Surgery Clinic, we studied 60 patients (30 males and 30 females), who were 18-47 years old (the mean of 25.6 years of age). The patients with M3 with moderate preoperative pain intensities, edema, and maximal mouth opening (MMO) data were recorded, and BDI was applied to determine their emotional states...
October 2020: Nigerian Journal of Clinical Practice
https://read.qxmd.com/read/32095922/effects-of-micro-osteoperforations-on-intraoral-miniscrew-anchored-maxillary-molar-distalization-a-randomized-clinical-trial
#12
RANDOMIZED CONTROLLED TRIAL
Kemal Gulduren, Hayriye Tumer, Ulas Oz
PURPOSE: The aim was to study the effects of micro-osteoperforations (MOPs) on miniscrew-supported maxillary molar distalization. METHODS: As part of a single center, split-mouth, randomized clinical trial, 20 eligible subjects were randomly recruited from patients who had applied to the orthodontics department of a university dental hospital. In the experimental group, subjects were randomized to receive MOPs to either the left or right maxillary molar region (n = 10)...
March 2020: Journal of Orofacial Orthopedics
https://read.qxmd.com/read/31706109/a-study-of-chewing-muscles-age-related-changes-in-type-i-collagen-and-matrix-metalloproteinase-2-expression
#13
JOURNAL ARTICLE
Mustafa Cicek, Mehmet Kemal Tumer, Velid Unsal
OBJECTIVE: In this study, the aim was to investigate the biochemical, physiological and histological changes that occur in masticatory muscles of the masticatory system with aging. DESIGN: In this study, 14 BALB/c mice were used. Animals were divided into two equal groups of seven. Group I was organized as the group of young animals (n = 7) and Group II as the group of adult animals (n = 7). After routine histological follow-up was performed, the tissues were embedded in paraffin...
January 2020: Archives of Oral Biology
https://read.qxmd.com/read/31405030/insights-on-the-use-of-%C3%AE-lipoic-acid-for-therapeutic-purposes
#14
REVIEW
Bahare Salehi, Yakup Berkay Yılmaz, Gizem Antika, Tugba Boyunegmez Tumer, Mohamad Fawzi Mahomoodally, Devina Lobine, Muhammad Akram, Muhammad Riaz, Esra Capanoglu, Farukh Sharopov, Natália Martins, William C Cho, Javad Sharifi-Rad
α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. It has various properties, among them great antioxidant potential and is widely used as a racemic drug for diabetic polyneuropathy-associated pain and paresthesia. Naturally, ALA is located in mitochondria, where it is used as a cofactor for pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase complexes. Despite its various potentials, ALA therapeutic efficacy is relatively low due to its pharmacokinetic profile...
August 9, 2019: Biomolecules
https://read.qxmd.com/read/31216776/-symphytum-species-a-comprehensive-review-on-chemical-composition-food-applications-and-phytopharmacology
#15
REVIEW
Bahare Salehi, Farukh Sharopov, Tugba Boyunegmez Tumer, Adem Ozleyen, Celia Rodríguez-Pérez, Shahira M Ezzat, Elena Azzini, Tahereh Hosseinabadi, Monica Butnariu, Ioan Sarac, Cristian Bostan, Krishnendu Acharya, Surjit Sen, Kadriye Nur Kasapoglu, Ceren Daşkaya-Dikmen, Beraat Özçelik, Navid Baghalpour, Javad Sharifi-Rad, Patrick Valere Tsouh Fokou, William C Cho, Natália Martins
Symphytum species belongs to the Boraginaceae family and have been used for centuries for bone breakages, sprains and rheumatism, liver problems, gastritis, ulcers, skin problems, joint pain and contusions, wounds, gout, hematomas and thrombophlebitis. Considering the innumerable potentialities of the Symphytum species and their widespread use in the world, it is extremely important to provide data compiling the available literature to identify the areas of intense research and the main gaps in order to design future studies...
June 18, 2019: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/31106438/ultrasound-guided-combined-pectoral-nerve-block-and-axillary-venipuncture-for-the-implantation-of-cardiac-implantable-electronic-devices
#16
JOURNAL ARTICLE
Serdar Bozyel, Ahmet Yalnız, Tolga Aksu, Tumer Erdem Guler, Samet Genez
BACKGROUND: Combined ultrasound (US)-guided pectoral nerves (PECS) block and axillary vein (AV) puncture for cardiac implantable electronic devices can be effective to achieve optimal perioperative pain management and prevent access-related complications. METHODS: A total of 36 patients who underwent combined US-guided PECS block and AV puncture were included. All routinely recorded parameters, including clinical and demographic characteristics, periprocedural medical administrations, the time taken for both PECS block and AV puncture, procedure time, postprocedural pain score, and procedure-related complications, were collected and analyzed...
July 2019: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/30129153/effect-of-a-functional-variant-of-tumor-necrosis-factor-%C3%AE-gene-in-temporomandibular-disorders-a-pilot-study
#17
JOURNAL ARTICLE
Kaan Yerliyurt, Ayse Feyda Nursal, Akin Tekcan, Nevin Karakus, Mehmet K Tumer, Serbulent Yigit
BACKGROUND: Temporomandibular disorders (TMD) are a group of conditions that cause chronic orofacial pain. The tumor necrosis factor β (TNF-β) is a proinflammatory cytokine that is involved in the various aspects of the inflammatory process including organization and maintenance, and in the arrangement of cells at the inflammation site. The purpose of this study was to evaluate the correlation between TNF-β +252A/G (rs909253) variant and susceptibility to TMD in a Turkish cohort. METHODS: The study included 104 patients (26 males, 78 females) with TMD and 126 healthy controls (44 males, 82 females)...
January 2019: Journal of Clinical Laboratory Analysis
https://read.qxmd.com/read/28705275/telangiectasia-macularis-eruptiva-perstans-report-of-three-cases
#18
JOURNAL ARTICLE
Gizem Tumer, Tiffany Jow, Sean McElligott, Robert A Schwartz, W Clark Lambert
Telangiectasia macularis eruptiva perstans (TMEP) is a rare, heterogeneous disease of mast cell proliferation. The variable clinical presentation of TMEP, coupled with its rarity, makes the recognition and diagnosis of this disease difficult and challenging for clinicians. The histopathologic findings with hematoxylin and eosin staining that distinguish TMEP from a normal skin biopsy can be so subtle that confirmation of the diagnosis with additional special stains (c-Kit, Giemsa, toluidine blue) is strongly recommended...
2017: Skinmed
https://read.qxmd.com/read/28359996/treatment-of-recurrent-aphthous-stomatitis-with-er-cr-ysgg-laser-irradiation-a-randomized-controlled-split-mouth-clinical-study
#19
RANDOMIZED CONTROLLED TRIAL
Hasan Guney Yilmaz, Mohammed Rateb Albaba, Ayse Caygur, Esra Cengiz, Fatma Boke-Karacaoglu, Hayriye Tumer
The present randomized controlled split mouth clinical study aimed to investigate the efficacy of Er,Cr:YSGG laser irradiation on pain reduction and healing rate of recurrent aphthous stomatitis. 40 patients with RAS were recruited for this study and RAS ulcerations of each patient were randomly assigned to the control or test group. In the test group, Er,Cr:YSGG laser with non-contact mode was used to irradiate RAS lesions. In the placebo group, RAS lesions were irradiated with the same device without laser emission...
May 2017: Journal of Photochemistry and Photobiology. B, Biology
https://read.qxmd.com/read/27875792/investigation-of-cd40-gene-rs4810485-and-rs1883832-mutations-in-patients-with-recurrent-aphthous-stomatitis
#20
JOURNAL ARTICLE
Serbulent Yigit, Akin Tekcan, Aydin Rustemoglu, Mehmet Kemal Tumer, Goknur Kalkan, Kaan Yerliyurt
OBJECTIVES: Recurrent aphthous stomatitis (RAS) is a common painful disorder affecting oral health, mucosa and overall quality of life. The etiopathogenesis of RAS remains unclear. RAS shows a large genetic diversity among the patients. In present study, we investigated whether CD40 gene rs4810485 and rs1883832 are associated with RAS and its clinical findings in Turkish patients. MATERIALS AND METHODS: Genomic DNA obtained from 387 individuals (160 patients with RAS and 227 healthy controls) were used in the study...
February 2017: Archives of Oral Biology
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