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Infection AND Central venous catheter

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https://www.readbyqxmd.com/read/28811093/risk-factors-for-infective-endocarditis-in-children-with-congenital-heart-diseases-a-nationwide-population-based-case-control-study
#1
Li-Chuan Sun, Chih-Cheng Lai, Cheng-Yi Wang, Ya-Hui Wang, Jen-Yu Wang, Yo-Ling Hsu, Yin-Lan Hu, En-Ting Wu, Ming-Tai Lin, Leticia B Sy, Likwang Chen
BACKGROUND: Infective endocarditis (IE) is uncommon in childhood. Its associated epidemiological characteristics in patients with congenital heart disease (CHD) remain unclear. METHODS: The study population included children born in Taiwan during the years 1997 to 2005 who were diagnosed as having CHD before 3years of age. All children were followed up until the end year of 2010, the diagnosis of infective endocarditis, or death. The demographic characteristics of patients with and without IE, the invasive procedures performed during 6months before the index date, the prophylactic antibiotics related to dental procedures, and in-hospital mortality were collected...
August 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28808369/ultrasound-guidance-for-central-venous-catheterization-a-step-further-to-prevent-malposition-of-central-venous-catheter-before-radiographic-confirmation
#2
Devinder Midha, Vipal Chawla, Arun Kumar, Amit Kumar Mandal
Ultrasound (USG) guidance has long been used for guiding central venous catheterization. USG provides direct visualization of needle puncture through the skin into the vein. Most of the time USG guidance is just limited to puncturing of the vein and seeing guidewire entering the vein while malpositioning of catheter occurs after that which is seen later on while checking chest radiograph. Repositioning of catheter after that becomes not only difficult requiring repeated chest radiograph to reconfirm position of catheter but also increases chances of infection with repeated manipulations...
July 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28807426/clinical-usefulness-of-catheter-drawn-blood-samples-and-catheter-tip-cultures-for-the-diagnosis-of-catheter-related-bloodstream-infections-in-neonatology-a-systematic-review
#3
REVIEW
Janita Ferreira, Paulo Augusto Moreira Camargos, Wanessa Trindade Clemente, Roberta Maia de Castro Romanelli
OBJECTIVES: Neonatal sepsis is the most frequent health care-associated infection in neonatal units. This study aimed to analyze articles on the clinical usefulness of catheter-drawn blood samples and catheter tip cultures for the diagnosis of intravascular catheter-related bloodstream infection (CRBSI) in neonates. METHODS: A systematic search was performed for studies published from 1987-2017, without language restriction. Observational studies carried out in neonates with CRBSI diagnosed using catheter-drawn blood samples or catheter tip cultures were included...
August 11, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28807074/a-model-to-predict-central-line-associated-bloodstream-infection-among-patients-with-peripherally-inserted-central-catheters-the-mpc-score
#4
Erica Herc, Payal Patel, Laraine L Washer, Anna Conlon, Scott A Flanders, Vineet Chopra
BACKGROUND Peripherally inserted central catheters (PICCs) are associated with central-line-associated bloodstream infections (CLABSIs). However, no tools to predict risk of PICC-CLABSI have been developed. OBJECTIVE To operationalize or prioritize CLABSI risk factors when making decisions regarding the use of PICCs using a risk model to estimate an individual's risk of PICC-CLABSI prior to device placement. METHODS Using data from the Michigan Hospital Medicine Safety consortium, patients that experienced PICC-CLABSI between January 2013 and October 2016 were identified...
August 15, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28798220/vascular-access-type-and-clinical-outcomes-among-elderly-patients-on-hemodialysis
#5
Timmy Lee, Mae Thamer, Qian Zhang, Yi Zhang, Michael Allon
BACKGROUND AND OBJECTIVES: The optimal type of initial permanent access for hemodialysis among the elderly is controversial. Duration of central venous catheter dependence, patient comorbidities, and life expectancy are important considerations in whether to place an arteriovenous fistula or graft. We used an observational study design to compare clinical outcomes in elderly patients who initiated hemodialysis with a central venous catheter and subsequently had an arteriovenous fistula or graft placed...
August 10, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28793993/taurolidine-citrate-heparin-lock-reduces-catheter-related-bloodstream-infections-in-intestinal-failure-patients-dependent-on-home-parenteral-support-a-randomized-placebo-controlled-trial
#6
Siri Tribler, Christopher F Brandt, Anne H Petersen, Jørgen H Petersen, Kristian A Fuglsang, Michael Staun, Per Broebech, Claus E Moser, Palle B Jeppesen
Background: In patients with intestinal failure who are receiving home parenteral support (HPS), catheter-related bloodstream infections (CRBSIs) inflict health impairment and high costs.Objective: This study investigates the efficacy and safety of the antimicrobial catheter lock solution, taurolidine-citrate-heparin, compared with heparin 100 IE/mL on CRBSI occurrence.Design: Forty-one high-risk patients receiving HPS followed in a tertiary HPS unit were randomly assigned in a double-blinded, placebo-controlled trial...
August 9, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28793102/deaths-among-the-elderly-with-icu-infections
#7
Álvaro Francisco Lopes de Sousa, Artur Acelino Francisco Luz Nunes Queiroz, Layze Braz de Oliveira, Luana Kelle Batista Moura, Denise de Andrade, Evandro Watanabe, Maria Eliete Batista Moura
Objective: to evaluate the clinical outcome of elderly patients admitted to intensive care units who had nosocomial infection, correlating the findings with sociodemographic and clinical variables. Method: descriptive research, performed with 308 elderly patients. The collection was made from medical records and covers the years 2012 to 2015. Uni-/bivariate analyses were performed. Results: a statistical association was found between the clinical outcome types and the variables age, length of stay, presence of previous comorbidities, main diagnosis, respiratory and urinary tract infections, use of central venous and indwelling urinary catheters, mechanical ventilation, and tracheostomy...
July 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28782178/staphylococcal-biofilm-gene-expression-on-biomaterials-a-methodological-study
#8
Annika Juhlin, Sara Svensson, Peter Thomsen, Margarita Trobos
The combination of increased healthcare access, universal aging, and infallible therapy demands, synergistically drive the need for the development of biomaterial technologies that mitigate the challenge of biomaterial-associated infections (BAI). Staphylococcus epidermidis and Staphylococcus aureus account for the majority of BAI due to their ability to accumulate in adherent multilayered biofilm. This investigation details the development of gene expression assays to evaluate the genetic processes of attachment, accumulation, maturation, and dispersal phases on biomaterials in vitro, while abiding by the Minimum Information for Publication of Quantitative Real-Time PCR Experiments (MIQE) guidelines...
August 7, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28777409/potential-role-of-a-subcutaneously-anchored-securement-device-in-preventing-dislodgment-of-tunneled-cuffed-central-venous-devices-in-pediatric-patients
#9
Andrea Dolcino, Antonio Salsano, Andrea Dato, Nicola Disma, Alessio Pini Prato, Filippo Bernasconi, Luigi Montagnini, Stefano Avanzini, Michela Bevilacqua, Giovanni Montobbio, Girolamo Mattioli, Clelia Zanaboni
INTRODUCTION: The potential drawbacks of tunneled-cuffed catheters are complications such as local or systemic infection, dislodgment, rupture, malfunction, and deep venous thrombosis. Aim of this study is to describe the incidence of complications, focusing on dislodgment and on the role of new securement devices in reducing this annoying issue. METHODS: We enrolled all pediatric patients with tunneled-cuffed central venous catheters (CVCs) inserted at the Giannina Gaslini Institute during a 16-month period...
August 27, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28767319/systematic-review-and-meta-analysis-of-the-utilization-of-ethanol-locks-in-pediatric-patients-with-intestinal-failure
#10
Riad Rahhal, Maisam A Abu-El-Haija, Lin Fei, Dawn Ebach, Sarah Orkin, Elizabeth Kiscaden, Conrad R Cole
BACKGROUND: Intestinal failure is a chronic condition related to loss of bowel length and/or function, resulting in dependence on central venous catheters for fluids and nutrition. Catheter use can be associated with significant complications, including catheter-related bloodstream infections (CRBSIs), which can lead to loss of vascular access, advancing intestinal failure associated-liver disease and death. Our objective was to evaluate the effectiveness and safety of ethanol locks as compared with standard heparin locks in pediatric intestinal failure...
August 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28749714/risk-factors-for-carbapenem-resistant-klebsiella-pneumoniae-infection-a-meta-analysis
#11
Pin Liu, Xuan Li, Mei Luo, Xuan Xu, Kewen Su, Shuai Chen, Ying Qing, Yingli Li, Jingfu Qiu
AIMS: Carbapenem-resistant Klebsiella pneumoniae (CRKP) infection has been rapidly emerging as a life-threatening nosocomial disease in many countries. However, studies on the corresponding risk factors of CRKP infection showed inconsistent results. To resolve these inconsistencies, we conducted a meta-analysis of previous studies on the potential risk factors of CRKP infection. The results of this study could be used to develop CRKP infection prevention strategies. METHODS: Relevant works were systematically searched from five electronic databases up to September 2016...
July 27, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28746169/traditional-long-term-central-venous-catheters-versus-transhepatic-venous-catheters-in-infants-and-young-children
#12
Amanda Marie Marshall, David A Danford, Christopher L Curzon, Venus Anderson, Jeffrey W Delaney
OBJECTIVES: Children with congenital heart disease may require long-term central venous access for intensive care management; however, central venous access must also be preserved for future surgical and catheterization procedures. Transhepatic venous catheters may be an useful alternative. The objective of this study was to compare transhepatic venous catheters with traditional central venous catheters regarding complication rate and duration of catheter service. DESIGN: Retrospective review of 12 congenital heart disease patients from September 2013 to July 2015 who underwent placement of one or more transhepatic venous catheters...
July 25, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28743701/correction-for-chaftari-et-al-a-novel-nonantibiotic-nitroglycerin-based-catheter-lock-solution-for-prevention-of-intraluminal-central-venous-catheter-infections-in-cancer-patients
#13
Anne-Marie Chaftari, Ray Hachem, Ariel Szvalb, Mahnaz Taremi, Bruno Granwehr, George Michael Viola, Sapna Amin, Andrew Assaf, Yazan Numan, Pankil Shah, Ketevan Gasitashvili, Elizabeth Natividad, Ying Jiang, Rebecca Slack, Ruth Reitzel, Joel Rosenblatt, Elie Mouhayar, Issam Raad
No abstract text is available yet for this article.
August 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28743533/should-non-bacteraemic-patients-with-a-colonized-catheter-receive-antimicrobial-therapy
#14
V De Egea, M Guembe, A Rodríguez-Borlado, M J Pérez-Granda, C Sánchez-Carrillo, E Bouza
OBJECTIVES: The impact of antimicrobial therapy on the outcomes of patients with colonized catheters and no bacteraemia has not been assessed. This study assessed whether targeted antibiotic therapy is related to a poor outcome in patients with positive cultures of blood drawn through a non-tunnelled central venous catheter (CVC) and without concomitant bacteraemia. METHODS: This was a retrospective study involving adult patients with positive blood cultures drawn through a CVC and negative peripheral vein blood cultures...
July 22, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28733213/risk-factors-for-the-infection-and-or-colonization-of-extended-spectrum-beta-lactamase-producing-bacteria-in-a-neonatal-intensive-care-unit-a-meta-analysis
#15
REVIEW
Xuan Li, Xuan Xu, Xianxian Yang, Mei Luo, Pin Liu, Kewen Su, Ying Qing, Shuai Chen, Jingfu Qiu, Yingli Li
BACKGROUND: Extended-spectrum beta-lactamase (ESBL)-producing bacteria are the important causes of healthcare associated infection in the neonatal intensive care unit (NICU). This study performed a meta-analysis to identify the risk factors associated with infection and/or colonization of ESBL-producing bacteria in the NICU. METHODS: Relevant studies in the literature published from January 1, 2000 to July 1, 2016 were searched in the electronic databases. The literature was screened and data were extracted according to the inclusion and exclusion criteria...
July 18, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28729382/recommended-clinical-trial-end-points-for-dialysis-catheters
#16
Michael Allon, Deborah J Brouwer-Maier, Kenneth Abreo, Kevin M Baskin, Kay Bregel, Deepa H Chand, Andrea M Easom, Leonard Mermel, Michele H Mokrzycki, Priti R Patel, Prabir Roy-Chaudhury, Surendra Shenoy, Rudolph P Valentini, Haimanot Wasse
Central venous catheters are used frequently in patients on hemodialysis as a bridge to a permanent vascular access. They are prone to frequent complications, including catheter-related bloodstream infection, catheter dysfunction, and central vein obstruction. There is a compelling need to develop new drugs or devices to prevent central venous catheter complications. We convened a multidisciplinary panel of experts to propose standardized definitions of catheter end points to guide the design of future clinical trials seeking approval from the Food and Drug Administration...
July 20, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28721474/single-stick-tunneled-central-venous-access-using-the-jugular-veins-in-infants-weighing-less-than-5%C3%A2-kg
#17
Will S Lindquester, C Matthew Hawkins, Eric J Monroe, Anne E Gill, Giridhar M Shivaram, F Glen Seidel, Matthew P Lungren
BACKGROUND: Despite the demonstrated feasibility of the single-stick technique in the femoral vein, its use in neonates and infants for placing central lines in internal and external jugular veins has not been reported. OBJECTIVE: Describe and assess the safety and efficacy of tunneled jugular central venous catheter placement performed under ultrasound (US) and fluoroscopic guidance in neonates and infants weighing <5 kg using the single-stick technique at three tertiary pediatric hospitals...
July 18, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28712369/a-hospital-based-matched-case-control-study-to-identify-risk-factors-for-clinical-infection-with-oxa-48-producing-klebsiella-pneumoniae-in-rectal-carriers
#18
A Madueño, J Gonzalez Garcia, A Aguirre-Jaime, M Lecuona
Asymptomatic colonisation of the gastrointestinal tract by carbapenemase-producing Enterobacteriaceae is an important reservoir for transmission, which may precede infection. This retrospective observational case-control study was designed to identify risk factors for developing clinical infection with OXA-48-producing Klebsiella pneumoniae in rectal carriers during hospitalisation. Case patients (n = 76) had carbapenemase-producing K. pneumoniae (CPKP) infection and positive rectal culture for CPKP. Control patients (n = 174) were those with rectal colonisation with CPKP but without CPKP infection...
September 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28705768/the-clinical-and-microbiological-characteristics-of-infections-in-burn-patients-from-the-formosa-fun-coast-dust-explosion
#19
Tzu-Chao Lin, Rui-Xin Wu, Chih-Chien Chiu, Ya-Sung Yang, Yi Lee, Jung-Chung Lin, Feng-Yee Chang
BACKGROUND/PURPOSE: Bloodstream infection is a leading cause of mortality among burn patients. This study aimed to evaluate the risk factors, causative pathogens, and the relationship between bloodstream infections and other infections among burn patients from the Formosa Fun Coast Dust Explosion. METHODS: This retrospective study evaluated the demographic and clinical characteristics, infection types, causative pathogen(s), and isolates' antibiotic susceptibilities from patients who were hospitalized between June 27 and September 31, 2015...
June 22, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28704490/the-synthetic-killer-peptide-kp-impairs-candida-albicans-biofilm-in-vitro
#20
Simona Paulone, Andrea Ardizzoni, Arianna Tavanti, Serena Piccinelli, Cosmeri Rizzato, Antonella Lupetti, Bruna Colombari, Eva Pericolini, Luciano Polonelli, Walter Magliani, Stefania Conti, Brunella Posteraro, Claudio Cermelli, Elisabetta Blasi, Samuele Peppoloni
Candida albicans is a commensal organism, commonly inhabiting mucosal surfaces of healthy individuals, as a part of the resident microbiota. However, in susceptible hosts, especially hospitalized and/or immunocompromised patients, it may cause a wide range of infections. The presence of abiotic substrates, such as central venous or urinary catheters, provides an additional niche for Candida attachment and persistence, particularly via biofilm development. Furthermore, Candida biofilm is poorly susceptible to most antifungals, including azoles...
2017: PloS One
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