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Infection AND Central venous catheter

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https://www.readbyqxmd.com/read/29927699/international-experience-with-minocycline-edta-and-ethanol-lock-for-salvaging-of-central-line-associated-bloodstream-infections
#1
Ray Hachem, Souha Kanj, Nelson Hamerschlak, Hala Saad, Fernanda Ferraz Assir, Nobuyoshi Mori, Ying Jiang, Fady Ghaly, Anne Marie Chaftari, Issam I Raad
BACKGROUND: The use of long-term central venous catheters (CVCs) could lead to serious bloodstream infections. Removal of the infected CVC and reinsertion of a new CVC are not always feasible and alternative lock therapy may be considered. We conducted a multicenter trial to assess the efficacy and safety of the lock therapy. METHODS: Between October 2013 and August 2014, we prospectively enrolled 20 patients with catheter-related bloodstream infections (CRBSIs) or central line-associated bloodstream infections (CLABSIs) in our sister institutions in three countries including Brazil, Lebanon, and Japan...
June 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29926785/central-line-bundle-for-prevention-of-central-line-associated-bloodstream-infection-for-totally-implantable-venous-access-devices-ports-in-pediatric-cancer-patients
#2
İlker Devrim, Yeliz Oruç, Bengü Demirağ, Ahu Kara, Mine Düzgöl, Selma Uslu, Nevbahar Yaşar, Sultan Aydın Köker, Ersin Töret, Nuri Bayram, Canan Vergin
OBJECTIVE: The clinical impact of central line bundle programs for central line-associated bloodstream infections has been well demonstrated in intensive care units. However, the experience of central line bundle programs in totally implantable venous access devices (ports) in pediatric-hematology patients was limited. METHODS: A retrospective study was designed to compare and evaluate the clinical impact of implementing a central line bundle for a 2-year 5-month period, including 10 months of prebundle period, 11 months of central line bundle (that includes needleless split-septum devices), and finally 8 months of central line bundle period in which single-use prefilled flushing devices were added to the previous central line bundle...
July 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29924154/central-venous-catheter-for-hemodialysis-incidence-of-infection-and-risk-factors
#3
Alessandra Amaral Schwanke, Mitzy Tannia Reichembach Danski, Letícia Pontes, Solena Ziemer Kusma, Jolline Lind
OBJECTIVE: To measure the incidence of infection in short-term central venous catheter for hemodialysis and to identify the associated risk factors. METHOD: Prospective cohort study conducted in a teaching hospital from September 2015 to April 2016. Patients requiring central venous catheter for hemodialysis were included and data was collected through direct and systematic observation of the catheter insertion procedure by the researchers. RESULTS: The final sample consisted of 69 patients, who used 88 catheters...
May 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29923938/predictive-factors-for-central-line-associated-bloodstream-infections-in-pediatric-cardiac-surgery-patients-with-chylothorax
#4
Stephanie G Waterhouse, Jeffrey E Vergales, Mark R Conaway, Laura Lee
OBJECTIVES: To assess the prevalence of central line-associated bloodstream infections in pediatric patients with and without chylothorax after cardiac surgery and identify risk factors that predict those patients at highest risk for developing a central line-associated bloodstream infection. DESIGN: Retrospective single-center cohort study. SETTING: A PICU located within a tertiary-care academic pediatric hospital. PATIENTS: All pediatric patients admitted to the PICU after cardiac surgery between 2008 and 2014...
June 19, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29923460/clinical-outcomes-of-totally-implantable-venous-access-port-placement-via-the-axillary-vein-in-patients-with-head-and-neck-malignancy
#5
Sun Hong, Tae-Seok Seo, Myung Gyu Song, Hae-Young Seol, Sang Il Suh, In-Seon Ryoo
PURPOSE: To evaluate the clinical outcomes and complications of totally implantable venous access port implantation via the axillary vein in patients with head and neck malignancy. MATERIALS AND METHODS: A total of 176 totally implantable venous access ports were placed via the axillary vein in 171 patients with head and neck malignancy between May 2012 and June 2015. The patients included 133 men and 38 women, and the mean age was 58.8 years (range: 19-84 years)...
June 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29917252/comparison-of-complications-between-peripheral-arm-ports-and-central-chest-ports-a-meta-analysis
#6
REVIEW
Shanshan Wu, Wanjiao Li, Qiongxiao Zhang, Shuting Li, Lizi Wang
AIM: To compare peripheral arm ports versus central chest ports in complication rates. BACKGROUND: Late complications of arm ports versus chest ports, including catheter-related infection, venous thrombosis and catheter obstruction, remain controversial. DESIGN: A meta-analysis conducted following the Cochrane handbook. DATA SOURCES: Studies published between 1950 - August 2017 were searched through Pubmed, Embase, Web of science and Cochrane library...
June 19, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29917174/-disinfection-of-injection-ports-a-systematic-overview-of-optimal-scrub-time
#7
Lars Breimer, Håkan Geijer, Lars Berggren
Central venous catheter bloodstream infections are an important cause of hospital-acquired infection with increased morbidity, mortality and cost. The incidence varies between countries and even hospitals. Needleless connector hubs are used on virtually all intravascular devices and colonization of these is considered the cause of much of the postinsertion catheter-related infections through breaks in aseptic technique and failure to disinfect properly. This systematic review evaluated 165 search hits on hub disinfection practices with particular emphasis on the time of scrubbing the connector for 15 sec but also the impact of measures of education and compliance...
June 15, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29915571/the-impact-of-biofilm-formation-on-the-persistence-of-candidemia
#8
Wei-Sin Li, Yi-Chun Chen, Shu-Fang Kuo, Fang-Ju Chen, Chen-Hsiang Lee
This study aimed to determine the predictors of persistent candidemia and examine the impact of biofilm formation by Candida isolates in adult patients with candidemia. Of the adult patients with candidemia in Kaohsiung Chang Gung Memorial Hospital between January 2007 and December 2012, 68 case patients with persistent candidemia (repeated candidemia after a 3-day systemic antifungal therapy) and 68 control patients with non-persistent candidemia ( Candida clearance from the bloodstream after a 3-day systemic antifungal therapy) were included based on propensity score matching and matching for the Candida species isolated...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29912033/analysis-of-healthcare-institutional-costs-of-pediatric-home-parenteral-nutrition-central-line-infections
#9
Bram P Raphael, Christina Hazenkamp, Mihail Samnaliev, Al Ozonoff
BACKGROUND: While previous literature suggests home parenteral nutrition (HPN) dependent children experience frequent complications like community acquired central line associated bloodstream infections (CLABSI), few studies have characterized the cost. OBJECTIVES: To evaluate institutional cost of community-acquired CLABSI in pediatric HPN patients. METHODS: This is a single center retrospective review of institutional costs for HPN patients with community-acquired CLABSI at a tertiary care children's hospital...
June 13, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29911010/three-dimensional-transesophageal-echocardiographic-diagnosis-of-catheter-endocarditis-hidden-in-intracaval-stent
#10
Rita Leonarda Musci, Cataldo Girasoli, Fabrizio Fumarola, Carlo D'Agostino, Paolo Colonna
In recent years, with an increasing number of central venous access procedures and cardiac implantable electronic device implantation, the incidence of infective endocarditis (IE) has become more prevalent. Two-dimensional transthoracic echocardiography (2D-TTE) and transesophageal echocardiography (TEE) are a key part of the evaluation of IE, but advances in three-dimensional echocardiography have enabled a better spatial resolution and visualization of cardiac structures, allowing the identification of any valvular vegetations, abscesses, or nodules...
April 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29910625/epidemiology-practice-patterns-and-prognostic-factors-for-candidemia-and-characteristics-of-fourteen-patients-with-breakthrough-candida-bloodstream-infections-a-single-tertiary-hospital-experience-in-japan
#11
Ryuichi Hirano, Yuichi Sakamoto, Junichi Kitazawa, Shoji Yamamoto, Hiroyuki Kayaba
Background: Candidemia is associated with high mortality, and its prognostic factors need to be examined in more detail in order to improve its management. A case of breakthrough (BT) candidemia is defined as the development of candidemia during antifungal therapy. The microbiological characteristics of and appropriate clinical practices for BT candidemia remain unclear. Objectives: The primary objective of the present study was to identify the prognostic factors of candidemia, while the secondary objective was to elucidate the microbiological characteristics of patients with BT candidemia...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29904809/effectiveness-of-antimicrobial-coated-central-venous-catheters-for-preventing-catheter-related-blood-stream-infections-with-the-implementation-of-bundles-a-systematic-review-and-network-meta-analysis
#12
REVIEW
Hongliang Wang, Hongshuang Tong, Haitao Liu, Yao Wang, Ruitao Wang, Hong Gao, Pulin Yu, Yanji Lv, Shuangshuang Chen, Guiyue Wang, Miao Liu, Yuhang Li, Kaijiang Yu, Changsong Wang
BACKGROUND: Catheter-related blood-stream infections (CRBSIs) are the most common complication when using central venous catheters (CVCs). Whether coating CVCs under bundles could further reduce the incidence of CRBSIs is unclear. We aimed to assess the effectiveness of implementing the use of bundles with antimicrobial-coated CVCs for preventing catheter-related blood-stream infections. METHODS: In this systematic review and network meta-analyses, we searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library in addition to the EMBASE, MEDLINE, CINAHL, and Web of Science databases for studies published before July 2017...
June 15, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29894411/central-line-bundle-maintenance-among-adults-in-a-university-hospital-intensive-care-unit-in-s%C3%A3-o-paulo-brazil-a-best-practice-implementation-project
#13
Karina Sichieri, Luciana Inaba Senyer Iida, Isa Rodrigues da Silveira Cabral de Menezes, Paulo Carlos Garcia, Talita Raquel Santos, Emília Peres, Gilcéria Tochika Shimoda, Flávia de Oliveira Motta Maia, Silvia Regina Secoli, Vilanice Alves de Araújo Püschel
OBJECTIVES: This implementation project aimed to identify the current practice in regards to central venous catheters (CVCs) maintenance to improve knowledge amongst nursing staff and to assess increased compliance with evidence-based best practice. INTRODUCTION: Central venous catheters are considered an important therapeutic resource for the administration of fluids, drugs, blood, collection of blood samples and hemodynamic monitoring. Despite the benefits, catheter use is associated with complications such as primary infection of the catheter-related bloodstream...
June 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29893318/percutaneous-nephrostomy-via-the-central-venous-catheter-in-combination-with-selective-ureteroscopic-lithotripsy-for-the-treatment-of-ureteral-stones-in-the-middle-upper-segment
#14
Dapang Rao, Haifeng Yu, Haibo Zhu, Kaiyuan Yu, Youhua He, Ping Duan
Objective: To explore the therapeutic outcome and significance of preoperative percutaneous nephrolithotomy (PCNL) via the central venous catheter in combination with two-step hard ureteroscopic lithotripsy for the treatment of ureteral stones in the middle-upper segment. Methods: The success rate and the occurrence of severe infection and perirenal hematoma were analyzed retrospectively in 37 patients who received preoperative PCNL via the central venous catheter in combination with two-step hard ureteroscopic lithotripsy for the treatment of ureteral stones in the middle-upper segment in our hospital between July 2012 and November 2014...
April 2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29876337/the-role-of-inflammation-in-venous-thromboembolism
#15
REVIEW
Brian R Branchford, Shannon L Carpenter
Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT), and pulmonary embolism (PE), is becoming increasingly recognized as a cause of morbidity and mortality in pediatrics, particularly among hospitalized children. Furthermore, evidence is accumulating that suggests the inflammatory response may be a cause, as well as consequence, of VTE, but current anticoagulation treatment regimens are not designed to inhibit inflammation. In fact, many established clinical VTE risk factors such as surgery, obesity, cystic fibrosis, sepsis, systemic infection, cancer, inflammatory bowel disease, and lupus likely modulate thrombosis through inflammatory mediators...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29872354/ultrasound-guided-central-venous-catheter-placement-in-the-emergency-department-experience-in-a-hospital-in-bogot%C3%A3-colombia
#16
German Devia Jaramillo, Jenny Torres Castillo, Freddy Lozano, Angélica Ramírez
Introduction: The use of central venous catheters (CVCs) in the emergency room (ER) is a valuable tool for the comprehensive management of critically ill patients; however, the positioning of these devices is not free of complications. Currently, the use of ultrasound is considered a useful and safe tool to carry out these procedures, but in Colombia, the number of emergency departments providing this tool is scarce and there is no literature describing the experience in our country. Objective: The objective of this study was to describe the experience regarding placement of ultrasound-guided CVCs by emergency physicians in an institution in Bogotá, as well as the associated complications...
2018: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/29863780/early-central-line-associated-blood-stream-infections-in-children-with-cancer-pose-a-risk-for-premature-catheter-removal
#17
Jacob Moell, Anna Svenningsson, Margareta Af Sandeberg, Magnus Larsson, Mats Heyman, Arja Harila-Saari, Anna Nilsson
AIM: This study examined the clinical characteristics of central line associated blood stream infections occurring within 30 days after insertion versus later infections in paediatric cancer patients, and the subsequent risk for premature catheter removal. METHODS: This was a retrospective study of children aged 0-18 years who were diagnosed with cancer from 2013-2014 at the Astrid Lindgren Children Hospital, Sweden. Clinical and microbiology data for each patient was collected for 365 days after the central venous catheter was inserted...
June 4, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29850301/-mycobacterium-mucogenicum-hand-infection-in-an-intravenous-drug-abuser
#18
Sijan Basnet, Izza Mir, Rashmi Dhital, Garima Basnet, Nitin Patel
Mycobacterium mucogenicum is a rapidly growing mycobacterium found ubiquitously in water sources. It has been reported to cause widespread infections with infection entry from wound or central venous catheters especially in immunocompromised patients. Diagnosis is made from blood cultures which may take at least a week. Management includes removal of the source or drainage of wound infections and combination antimicrobial therapy.
2018: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29844050/antimicrobial-efficacy-and-safety-of-a-novel-gas-plasma-activated-catheter-lock-solution
#19
Sudhir Bhatt, Poonam Mehta, Chen Chen, Dayle A Daines, Leonard A Mermel, Hai-Lan Chen, Michael G Kong
Antimicrobial lock solutions are important for prevention of microbial colonization and infection of long-term central venous catheters. We investigated the efficacy and safety of a novel antibiotic-free lock solution formed from gas plasma-activated disinfectant (PAD). Using a luminal biofilm model, viable cells of methicillin-resistant Staphylococcus aureus , Staphylococcus epidermidis , Pseudomonas aeruginosa , and Candida albicans in mature biofilms were reduced by 6 - 8 orders of magnitude with a PAD lock for 60 minutes...
May 29, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29807830/review-of-bedside-surgeon-performed-ultrasound-in-pediatric-patients
#20
REVIEW
Patrick C Bonasso, Melvin S Dassinger, Deidre L Wyrick, Lori A Gurien, Jeffrey M Burford, Samuel D Smith
PURPOSE: Pediatric surgeon performed bedside ultrasound (PSPBUS) is a targeted examination that is diagnostic or therapeutic. The aim of this paper is to review literature involving PSPBUS. METHODS: PSPBUS practices reviewed in this paper include central venous catheter placement, physiologic assessment (volume status and echocardiography), hypertrophic pyloric stenosis diagnosis, appendicitis diagnosis, the Focused Assessment with Sonography for Trauma (FAST), thoracic evaluation, and soft tissue infection evaluation...
May 8, 2018: Journal of Pediatric Surgery
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