Quentin Richier, Benjamin De Valence, Dorothée Chopin, Emmanuelle Gras, Laura I Levi, Yasmine Abi Aad, Jérôme Pacanowski, Jean-Luc Meynard, Léo Plaçais, Dorothée Fey, Priscille Couture, Guillaume Martin-Blondel, Vincent Pestre, Juliette Woessner, Sophie Ancellin, Pierre Weyrich, Benjamin Carpentier, Salim Idri, Pierre Tiberghien, Laure Surgers, Thomas Hueso, Karine Lacombe
The emergence of SARS-CoV-2 Omicron variant has led to a complete reconfiguration of the therapeutic landscape, with all monoclonal antibodies having lost any neutralization activity. We report here a case series of 75 immunocompromised patients infected by the Omicron variant who benefited from COVID-19 convalescent plasma (CCP). At Day 28, the overall survival was 76% (95% CI 67-86) with no significant difference in the clinical outcome between patients with hematological malignancies, solid organ transplantation or autoimmune diseases...
March 2024: Influenza and Other Respiratory Viruses