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https://www.readbyqxmd.com/read/28434420/environmental-sampling-coupled-with-real-time-pcr-and-genotyping-to-investigate-the-source-of-a-q-fever-outbreak-in-a-work-setting
#1
A Hurtado, E Alonso, I Aspiritxaga, I López Etxaniz, B Ocabo, J F Barandika, J I Fernández-Ortiz DE Murúa, F Urbaneja, R Álvarez-Alonso, I Jado, A L García-Pérez
A Q fever outbreak was declared in February 2016 in a company that manufactures hoists and chains and therefore with no apparent occupational-associated risk. Coxiella burnetii infection was diagnosed by serology in eight of the 29 workers of the company; seven of them had fever or flu-like signs and five had pneumonia, one requiring hospitalisation. A further case of C. burnetii pneumonia was diagnosed in a local resident. Real-time PCR (RTi-PCR) showed a widespread distribution of C. burnetii DNA in dust samples collected from the plant facilities, thus confirming the exposure of workers to the infection inside the factory...
April 24, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28420187/device-free-localization-via-an-extreme-learning-machine-with-parameterized-geometrical-feature-extraction
#2
Jie Zhang, Wendong Xiao, Sen Zhang, Shoudong Huang
Device-free localization (DFL) is becoming one of the new technologies in wireless localization field, due to its advantage that the target to be localized does not need to be attached to any electronic device. In the radio-frequency (RF) DFL system, radio transmitters (RTs) and radio receivers (RXs) are used to sense the target collaboratively, and the location of the target can be estimated by fusing the changes of the received signal strength (RSS) measurements associated with the wireless links. In this paper, we will propose an extreme learning machine (ELM) approach for DFL, to improve the efficiency and the accuracy of the localization algorithm...
April 17, 2017: Sensors
https://www.readbyqxmd.com/read/28398550/the-influence-of-socioeconomic-status-on-gestational-weight-gain-a-systematic-review
#3
E C O'Brien, G Alberdi, F M McAuliffe
Background: Despite a large number of publications regarding the association between socioeconomic status (SES) and gestational weight gain (GWG), the literature is inconsistent. We conducted a systematic review of current evidence relating to the association between SES and GWG, according to the Institute of Medicine (IOM) 2009 guidelines. Methods: Six electronic databases were searched, with the final search run on first July 2016. The PRISMA Statement guidelines were followed and a modified version of the RTI Item Bank was used to assess risk of bias within studies...
April 7, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28394180/antibiotic-treatment-failure-when-consulting-patients-with-respiratory-tract-infections-in-general-practice-a-qualitative-study-to-explore-danish-general-practitioners-perspectives
#4
Margrethe Bordado Sköld, Rune Aabenhus, Ann Dorrit Guassora, Marjukka Mäkelä
BACKGROUND: Prescribing antibiotics for acute respiratory tract infections (RTIs) is common in primary healthcare although most of these infections are of viral origin and antibiotics may not be helpful. Some of these prescriptions will not be associated with a quick recovery, and might be regarded as cases of antibiotic treatment failure (ATF). OBJECTIVES: We studied antibiotic treatment failure in patients with acute RTIs from a general practitioner (GP) perspective, aiming to explore (i) GPs' views of ATF in primary care; (ii) how ATF influences the doctor-patient relationship; and (iii) GPs' understanding of patients' views of ATF...
December 2017: European Journal of General Practice
https://www.readbyqxmd.com/read/28369370/diagnostic-performance-and-clinical-feasibility-of-a-point-of-care-test-for-respiratory-viral-infections-in-primary-health-care
#5
Andrea H L Bruning, Wilhelmina B de Kruijf, Henk C P M van Weert, Wim L M Willems, Menno D de Jong, Dasja Pajkrt, Katja C Wolthers
Background.: Inappropriately high levels of antibiotics are still prescribed in primary health care for respiratory tract infections (RTIs). Access to diagnostic point-of-care tests (POCTs) for RTIs might reduce this over-prescription. Objective.: The purpose of our study was to determine the diagnostic performance and clinical feasibility of a recently developed diagnostic POCT for respiratory viruses, the mariPOC®, in a Dutch primary healthcare setting. Methods...
March 24, 2017: Family Practice
https://www.readbyqxmd.com/read/28347279/simultaneous-detection-of-respiratory-syncytial-virus-and-human-metapneumovirus-by-one-step-multiplex-real-time-rt-pcr-in-patients-with-respiratory-symptoms
#6
Huey-Ling You, Shun-Jen Chang, Hong-Ren Yu, Chia-Chin Li, Chang-Han Chen, Wei-Ting Liao
BACKGROUND: Both respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are important viral pathogens causing respiratory tract infection (RTI) in the pediatric population. However, the clinical manifestations of RSV and hMPV infections are similar. Therefore, a reliable and rapid diagnostic tool is needed for diagnostic performance. METHODS: In order to optimize diagnosis efficiency of RTI, the aim of this study is to establish a rapid and advanced method for simultaneous detecting RSV and hMPV in nasopharyngeal aspirates specimens from patients...
March 27, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28334924/throat-swabs-in-children-with-respiratory-tract-infection-associations-with-clinical-presentation-and-potential-targets-for-point-of-care-testing
#7
Hannah V Thornton, Alastair D Hay, Niamh M Redmond, Sophie L Turnbull, Hannah Christensen, Tim J Peters, John P Leeming, Andrew Lovering, Barry Vipond, Peter Muir, Peter S Blair
Background and objectives.: Diagnostic uncertainty over respiratory tract infections (RTIs) in primary care contributes to over-prescribing of antibiotics and drives antibiotic resistance. If symptoms and signs predict respiratory tract microbiology, they could help clinicians target antibiotics to bacterial infection. This study aimed to determine relationships between symptoms and signs in children presenting to primary care and microbes from throat swabs. Methods.: Cross-sectional study of children ≥3 months to <16 years presenting with acute cough and RTI, with subset follow-up...
February 18, 2017: Family Practice
https://www.readbyqxmd.com/read/28323558/reproductive-tract-infections-attitude-and-barriers-among-marginalized-fisher-women-in-kerala-south-india
#8
Manoj A Thomas, Poornima Narayan
Reproductive tract infections (RTIs) are the cause of severe gynecological and maternal morbidity in India. In marginalized communities, women persevere quietly when faced with a culturally sensitive health issue such as an RTI. To hypothesize on the differential health behavior and low levels of reported incidents among women living in marginalized communities, we undertake an exploratory study in a coastal fishermen community in South India. We identify barriers influencing decisions to seek curative and preventive medical care...
April 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28318450/repeated-sprints-in-fasted-state-impair-reaction-time-performance
#9
Anissa Cherif, Romain Meeusen, Abdulaziz Farooq, Walid Briki, Mohamed Amine Fenneni, Karim Chamari, Bart Roelands
OBJECTIVE: The aim of this study was to assess the effects of 3-day Islamic intermittent fasting (3d-IF) on cognitive performance and serum levels of neurotrophic factors (brain-derived neurotrophic factor [BDNF] and vascular endothelial growth factor [VEGF]) before and after repeated sprints. METHODS: Twenty-one physically active male Muslims (29.8 ± 5.9 years, exercising 4 ± 1.5 times/week) were randomly assigned to one of 2 experimental sessions: the control or nonfasting session (CS) or the fasting session (FS)...
March 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28298366/antibiotics-for-acute-respiratory-tract-infections-a-mixed-methods-study-of-patient-experiences-of-non-medical-prescriber-management
#10
Molly Courtenay, Samantha Rowbotham, Rosemary Lim, Rhian Deslandes, Karen Hodson, Katie MacLure, Sarah Peters, Derek Stewart
OBJECTIVE: To (1) explore patients' expectations and experiences of nurse and pharmacist non-medical prescriber-led management of respiratory tract infections (RTIs), (2) examine whether patient expectations for antibiotics affect the likelihood of receiving them and (3) understand factors influencing patient satisfaction with RTI consultations. DESIGN: Mixed methods. SETTING: Primary care. PARTICIPANTS: Questionnaires from 120 patients and follow-up interviews with 22 patients and 16 nurse and pharmacist non-medical prescribers (NMPs)...
March 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28288733/potential-gains-in-life-expectancy-by-improving-road-safety-in-china
#11
Q Li, S Ma, D Bishai, A A Hyder
OBJECTIVES: Road traffic injuries (RTI) cause a significant number of injuries and deaths in China every year; the World Health Organization estimated 261,367 deaths due to RTI in 2013. As a result of the ongoing growth of China's economy, road construction and motorisation, RTI are expected to impose a heavy health burden in the future. However, the public and policy makers have not widely perceived RTI as a public health issue commensurate with its consequences, in part, due to a lack of intuitive indicator measuring the health impact...
March 2017: Public Health
https://www.readbyqxmd.com/read/28286828/predictive-factors-of-poor-outcome-in-road-traffic-injures-a-retrospective-cohort-study
#12
Hamid Reza Hatamabadi, Majid Shojaee, Parvin Kashani, Mohammad Mehdi Forouzanfar, Dorrin Aghajani Nargesi, Mohammad Reza Amini Esfahani
INTRODUCTION: Road traffic injuries (RTI) are among the most important health problems worldwide as they cause more than 1.2 million deaths and 50 million injuries each year. Therefore, the present study aims to evaluate the outcome and aftermath of RTI in those who were injured and hospitalized due to a traffic accident. METHODS: In the present retrospective cohort study with a one-year follow-up, data were extracted from the profiles of the RTI hospitalized patients...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28286237/retrospectively-supervised-click-decoder-calibration-for-self-calibrating-point-and-click-brain-computer-interfaces
#13
Beata Jarosiewicz, Anish A Sarma, Jad Saab, Brian Franco, Sydney S Cash, Emad N Eskandar, Leigh R Hochberg
Brain-computer interfaces (BCIs) aim to restore independence to people with severe motor disabilities by allowing control of acursor on a computer screen or other effectors with neural activity. However, physiological and/or recording-related nonstationarities in neural signals can limit long-term decoding stability, and it would be tedious for users to pause use of the BCI whenever neural control degrades to perform decoder recalibration routines. We recently demonstrated that a kinematic decoder (i.e. a decoder that controls cursor movement) can be recalibrated using data acquired during practical point-and-click control of the BCI by retrospectively inferring users' intended movement directions based on their subsequent selections...
March 8, 2017: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/28260879/occupational-copd-and-job-exposure-matrices-a-systematic-review-and-meta-analysis
#14
REVIEW
Steven Sadhra, Om P Kurmi, Sandeep S Sadhra, Kin Bong Hubert Lam, Jon G Ayres
BACKGROUND: The association between occupational exposure and COPD reported previously has mostly been derived from studies relying on self-reported exposure to vapors, gases, dust, or fumes (VGDF), which could be subjective and prone to biases. The aim of this study was to assess the strength of association between exposure and COPD from studies that derived exposure by job exposure matrices (JEMs). METHODS: A systematic search of JEM-based occupational COPD studies published between 1980 and 2015 was conducted in PubMed and EMBASE, followed by meta-analysis...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28213241/elime-assay-vs-real-time-pcr-and-conventional-culture-method-for-an-effective-detection-of-salmonella-in-fresh-leafy-green-vegetables
#15
L Fabiani, E Pucci, E Delibato, G Volpe, S Piermarini, D De Medici, F Capuano, G Palleschi
The detection of Salmonella according to EC regulation is still primarily based on traditional microbiological culture methods that may take several days to be completed. The purpose of this work is to demonstrate the applicability of an Enzyme-Linked-Immuno-Magnetic-Electrochemical (ELIME) assay, recently developed by our research group for the detection of salmonella in irrigation water, in fresh (raw and ready-to-eat) leafy green vegetables by comparison with Real-Time PCR (RTi-PCR) and ISO culture methods...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28207666/are-they-complying-physicians-knowledge-attitudes-and-readiness-to-change-regarding-low-back-pain-treatment-guideline-adherence
#16
Sheera Epstein-Sher, Dena H Jaffe, Amnon Lahad
STUDY DESIGN: Cross-sectional survey of 145 primary care practitioners (PCPs). OBJECTIVE: To examine low back pain (LBP) guideline knowledge, readiness to implement (RTI) these guidelines, and LBP attitudes and beliefs among Israeli PCPs and determine whether physician age, guideline familiarity, and medical specialty affect these variables. SUMMARY OF BACKGROUND DATA: LBP is a common condition managed primarily by PCPs. Little is known, however, about physician's LBP knowledge, attitudes, and beliefs and how these factors (knowledge, A&B) influence their practice behavior...
February 15, 2017: Spine
https://www.readbyqxmd.com/read/28155741/determinants-of-fatal-road-traffic-injuries-in-c%C3%A3-te-d%C3%A2-ivoire-from-2002-to-2011
#17
Joseph Bénié Bi Vroh, Issaka Tiembre, Daniel Kouadio Ekra, Marie-Noëlle Ano Ama, Orlando Missiemoun Ka, Simplice Ncho Dagnan, Janine Tagliante-Saracino
Introduction : In most developing countries, with rapidly changing lifestyles, urbanization, and increasing numbers of vehicles, Road Traffic Injuries (RTI) are expected to have a growing impact on mortality and morbidity.The objective of this study was to identify factors associated with fatal RTI in Côte d’Ivoire.Methods : We conducted a cross-sectional study of data concerning RTI in Côte d’Ivoire over a ten-year period (2002 to 2011) from the Road Safety Office (RSO) database. All RTI reported by the police were included in the study...
November 25, 2016: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/28141491/combination-antiretroviral-therapy-cart-and-cell-cell-spread-of-wild-type-and-drug-resistant-hiv-1
#18
Boghuma Kabisen Titanji, Deenan Pillay, Clare Jolly
HIV-1 disseminates between T cells either by cell-free infection or by highly-efficient direct cell-cell spread. The high local multiplicity that characterizes cell-cell infection causes variability in the effectiveness of antiretroviral drugs applied as single agents. Whereas Protease Inhibitors (PIs) are effective inhibitors of HIV-1 cell-cell and cell-free infection, some Reverse Transcriptase Inhibitors (RTIs) show reduced potency; however antiretrovirals are not administered as single agents and are clinically used as combination antiretroviral therapy (cART)...
January 28, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28125369/payer-perspectives-on-patient-reported-outcomes-in-health-care-decision-making-oncology-examples
#19
Andrew P Brogan, Carla DeMuro, Amy M Barrett, Denise D'Alessio, Vasudha Bal, Susan L Hogue
BACKGROUND: Health authorities and payers increasingly recognize the importance of patient perspectives and patient-reported outcomes (PROs) in health care decision making. However, given the broad variety of PRO endpoints included in clinical programs and variations in the timing of PRO data collection and country-specific needs, the role of PRO data in reimbursement decisions requires characterization. OBJECTIVES: To (a) determine the effect of PRO data on market access and reimbursement decisions for oncology products in multiple markets and (b) assess the effect of PRO data collected after clinical progression on payer decision making...
February 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28122841/antibiotic-management-of-children-with-infectious-diseases-in-dutch-primary-care
#20
Anne R J Dekker, Theo J M Verheij, Alike W van der Velden
Background.: Childhood infections are common in general practice. Although clinical guidelines recommend restrictive antibiotic use for children, antibiotics are too often prescribed. Objective.: The aim of this study was to obtain insight in antibiotic prescribing for children related to clinical diagnoses. This is pivotal to define improvement strategies in the antibiotic management. Methods.: In this observational study, we used consultation data collected from 45 general practices in the Netherlands in 2012...
April 1, 2017: Family Practice
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