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Bone allograft

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https://www.readbyqxmd.com/read/28928818/the-value-of-computer-assisted-navigation-for-bone-reconstruction-after-tumor-resection
#1
Xuejun Peng, Fengping Wang, Jing Su
This study was designed to evaluate the use of computer-assisted navigation with computed tomography (CT) images for bone reconstruction after resection in malignant bone tumor treatment. Forty-five patients with malignant bone tumors were recruited for this study. CT scan images in a computer-assisted navigation system were used to assist during the osteotomy, the pairing with allografts, and the monitoring of the allograft and joint lines to perform joint reconstruction. Our results show that osteotomy and allograft pairing were successful in all patients...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28914208/a-systematic-review-of-clinical-studies-investigating-mesenchymal-stem-cells-for-fracture-non-union-and-bone-defects
#2
Kieran Killington, Reza Mafi, Pouya Mafi, Wasim Khan
Fracture non-union is a significant problem with a wide demographic and massive socioeconomic elements, as well as the clinical difficulties it presents. Conventional treatments with autograft and allograft bone grafting pose serious difficulties, thus, it is necessary to develop novel techniques with our ever increasing knowledge of bioengineering using natural materials. Papers were searched from a variety of sources, not limited to English-language studies or only published papers. Papers had to meet the definition of fracture non-union or bone defect and had to be clinical trials, using human MSCs...
September 15, 2017: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28914114/shining-dead-bone-cause-for-cautious-interpretation-of-18-f-naf-pet-scans
#3
Magnus Bernhardsson, Olof Sandberg, Marcus Ressner, Jacek Koziorowski, Jonas Malmquist, Per Aspenberg
Background and purpose - [(18)F]Fluoride ([(18)F]NaF) PET scan is frequently used for estimation of bone healing rate and extent in cases of bone allografting and fracture healing. Some authors claim that [(18)F]NaF uptake is a measure of osteoblastic activity, calcium metabolism, or bone turnover. Based on the known affinity of fluoride to hydroxyapatite, we challenged this view. Methods - 10 male rats received crushed, frozen allogeneic cortical bone fragments in a pouch in the abdominal wall on the right side, and hydroxyapatite granules on left side...
September 15, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28904437/cryptococcal-infection-in-transplant-kidney-manifesting-as-chronic-allograft-dysfunction
#4
C Agrawal, V Sood, A Kumar, V Raghavan
Invasive fungal infections (IFIs) are a significant cause of morbidity in solid organ transplant (SOT) recipients. Common causes among them are Aspergillus, Candida, and Cryptococcus. Antifungal prophylaxis has led to decrease in overall incidence of IFI; however, there is very little decline in the incidence of Cryptococcal infections of SOT recipients because effective prophylaxis is not available against this infectious agent. Spectrum of manifestation of Cryptococcal infection varies in immunocompetent and immunocompromised host with subclinical and self-limiting with lungs being the primary site in immunocompetent and central nervous system as the most common site in an immunocompromised host...
September 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/28895428/decreased-migration-with-locally-administered-bisphosphonate-in-cemented-cup-revisions-using-impaction-bone-grafting-technique
#5
Vasileios Zampelis, Ola Belfrage, Magnus Tägil, Martin Sundberg, Gunnar Flivik
Background and purpose - Impaction bone grafting (IBG) in revision hip surgery is an established method in restoring bone stock deficiencies. We hypothesized that local treatment of the morsellized allograft with a bisphosphonate in cemented revision would, in addition to increased bone density, also reduce the early migration of the cup as measured by radiostereometry (RSA). Patients and methods - 20 patients with aseptic cup loosening underwent revision using the IBG technique. The patients were randomized to either clodronate (10 patients) or saline (10 patients, control group) as local adjunct to the morsellized bone...
September 12, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28890904/thirty-year-experience-with-acl-reconstruction-using-patellar-tendon-a-critical-evaluation-of-revision-and-reoperation
#6
Andrew J Riff, Timothy J Luchetti, Alexander E Weber, Jaskarndip Chahal, Bernard R Bach
BACKGROUND: During the preoperative discussion prior to anterior cruciate ligament reconstruction (ACLR), patients are often interested in data regarding rates of revision reconstruction, reoperation, concomitant pathologic changes, and future contralateral ACL injury. PURPOSE: To analyze a single surgeon's experience with primary and revision ACLR over a 30-year interval, focusing on incidence and risk factors for revision and reoperation. STUDY DESIGN: Case series; Level of evidence, 4...
August 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28886100/biomechanical-evaluation-of-tibial-bone-adaptation-after-revision-total-knee-arthroplasty-a-comparison-of-different-implant-systems
#7
María Paz Quilez, Belen Seral, María Angeles Pérez
The best methods to manage tibial bone defects following total knee arthroplasty remain under debate. Different fixation systems exist to help surgeons reconstruct knee osseous bone loss (such as tantalum cones, cement, modular metal augments, autografts, allografts and porous metaphyseal sleeves) However, the effects of the various solutions on the long-term outcome remain unknown. In the present work, a bone remodeling mathematical model was used to predict bone remodeling after total knee arthroplasty (TKA) revision...
2017: PloS One
https://www.readbyqxmd.com/read/28878542/ewings-sarcoma-of-ilium-resection-and-reconstruction-with-femoral-head-allograft
#8
Yugal Karkhur, Lalit Maini, Anurag Tiwari, Tarun Verma
Ewing's sarcoma is a common malignant bone tumor seen in 5-15 years age group. It often arises from diaphysis of long bones. Ewing's sarcoma arising from the ilium is very rare, and it has an unfavourable prognosis. We present a rare case report of Ewings sarcoma of ilium with no metastasis in a two and a half year old boy, who was treated with neoadjuvant chemotherapy followed by surgical excision of the tumor and reconstruction using allograft from the femoral head fixed with multiple k-wires and screw. The patient is disease free at one year follow up and the allograft has taken the shape of growing ilium and excellent functionality and gait with minimal limp...
August 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28877329/comparison-of-knee-stability-and-synovial-fluid-alterations-in-anterior-cruciate-ligament-reconstruction-with-a-hamstring-autograft-or-an-allograft
#9
Rui Yang, Haiquan Deng, Jingyi Hou, Yi Ouyang, Zhong Chen, Bin Song, Yunfeng Zhou, Weiquan Tan, Weiping Li, Huiyong Shen
This study compared knee stability and alterations in the composition of synovial fluid among patients who underwent arthroscopic anterior cruciate ligament (ACL) reconstruction with either a hamstring autograft or a hamstring allograft. This prospective cohort study enrolled 175 patients. Of these patients, 90 underwent hamstring tendon autograft ACL reconstruction. The remaining patients (n=85) underwent hamstring tendon allograft ACL reconstruction. All of the patients had a minimum of 1 year of follow-up (mean, 2...
September 6, 2017: Orthopedics
https://www.readbyqxmd.com/read/28875562/a-new-composite-hydrogel-combining-the-biological-properties-of-collagen-with-the-mechanical-properties-of-a-supramolecular-scaffold-for-bone-tissue-engineering
#10
Mathieu Maisani, Sophia Ziane, Camille Ehret, Lucie Levesque, Robin Siadous, Jean-François Le Meins, Pascale Chevalier, Philippe Barthélémy, Hugo De Oliveira, Joëlle Amédée, Diego Mantovani, Olivier Chassande
Tissue engineering is a promising alternative to autografts, allografts or biomaterials to address the treatment of severe and large bone lesions. Classically, tissue engineering products associate a scaffold and cells, and are implanted or injected into the lesion. These cells must be embedded in an appropriate biocompatible scaffold, which offers a favourable environment for their survival and differentiation. Here, we designed a composite hydrogel composed of collagen I, an extracellular matrix protein widely used in several therapeutic applications, which we associated with a physical hydrogel generated from a synthetic small amphiphilic molecule...
September 6, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28870647/comparison-between-autogenous-iliac-bone-and-freeze-dried-bone-allograft-for-repair-of-alveolar-clefts-in-the-presence-of-plasma-rich-in-growth-factors-a-randomized-clinical-trial
#11
Gholamreza Shirani, Amir J Abbasi, Simin Z Mohebbi, Mohammad Moharrami
PURPOSE: This study aimed to compare the effectiveness of alveolar cleft repair using iliac bone and freeze-dried bone allograft (FDBA) in the presence of plasma rich in growth factors (PRGF). MATERIALS AND METHODS: Patients with unilateral alveolar cleft (n = 32) were randomly allocated to either the iliac plus PRGF group or the FDBA plus PRGF group. CBCT images were obtained before and 6 months after the surgery to assess the regenerated bone volume. Paired t-tests and two-way analysis of variance (ANOVA) were applied to analyze the data using SPSS 16...
August 7, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28867053/osteochondral-autograft-and-allograft-transplantation-in-the-talus
#12
REVIEW
Alan Ng, Kaitlyn Bernhard
Large, symptomatic, focal chondral, and osteochondral lesions of the ankle are treated with osteochondral autograft/allograft transplantation (OAT) procedure, a reconstructive bone grafting technique that uses one or more cylindrical osteochondral grafts from an area of low impact or allograft source and transplants them into the prepared defect site on the talus. This technique allows defects to be filled with mature, hyaline articular cartilage. Acute or chronic chondral or osteochondral lesions can be debilitating; provided here is a review of osteochondral autograft or allograft transplantation...
October 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28865593/obtaining-local-bone-graft-for-evans-calcaneal-osteotomy-in-pes-planovalgus-deformity-correction
#13
Khalid M S Mohamed, Christopher Fenelon, John G Galbraith, Lester G D'Souza
Lateral column lengthening osteotomy is very useful surgical technique in treating stage II of pes planovalgus deformity of the foot. Either autograft from the iliac crest or allograft can be used for this purpose. In our technique we describe a novel method of obtaining bone graft locally from the calcaneus and therefore avoiding complications and morbidity associated with iliac crest graft.
September 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28865420/risk-factors-for-failure-of-revision-total-hip-arthroplasty-using-a-kerboull-type-acetabular-reinforcement-device
#14
Shinya Hayashi, Takayuki Nishiyama, Shingo Hashimoto, Tomoyuki Matsumoto, Koji Takayama, Kazunari Ishida, Kotaro Nishida, Ryosuke Kuroda
BACKGROUND: The present study aimed to identify the risk factors associated with revision total hip arthroplasty (THA) failure using a Kerboull-type (KT) plate. METHODS: We analyzed 77 revision THAs using cemented acetabular components with a KT plate for aseptic loosening between May 2000 and March 2012. We examined the association of bone graft type, acetabular bone defects, age at the time of surgery, preoperative Japanese Orthopaedic Association (JOA) score, postoperative JOA hip score, and body mass index, with radiographic failure as the outcome...
September 2, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28864387/tenosynovial-giant-cell-tumor-in-the-midfoot-treated-with-femoral-head-allograft-reconstruction
#15
Daniel J Fuchs, Paul J Switaj, Terrance D Peabody, Anish R Kadakia
Tenosynovial giant cell tumor (also known as giant cell tumor of tendon sheath or pigmented villonodular synovitis) is a rare soft tissue tumor that arises from the tenosynovium of a tendon sheath or the synovium of a diarthrodial joint. This disease process occurs infrequently in the foot and ankle but can result in significant bone erosion and destructive changes of affected joints. These cases are challenging to treat, because the tumor most commonly presents in young, active patients and can be associated with extensive bone loss...
August 29, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28863322/il-17-contributes-to-the-pathogenesis-of-obliterative-bronchiolitis-via-regulation-of-m1-macrophages-polarization-in-murine-heterotopic-trachea-transplantation-models
#16
Qingshu Meng, Jie Liu, Fang Lin, Luer Bao, Yuyu Jiang, Liang Zheng, Jinjun Tie, Lin Zhang, Xiaoting Liang, Lu Wei, Yuan Li, Huimin Fan, Xiaohui Zhou
Acute allograft rejection is a principal conundrum in lung obliterative bronchiolitis (OB). Monocytes/macrophages infiltration has been proved to be the main reason for acute rejection. IL-17 contributes to the recruitment and function of macrophages. However, the mechanism of IL-17 underlying OB progression remains elusive. In the present study, we showed that the deficiency of IL-17 attenuated the pathology of murine heterotopic trachea allografts. Compared to WT recipients, IL-17(-/-) mice displayed higher frequency of CD206+ cells and lower ratio of CD86+ cells among F4/80+ macrophages in allografts and spleens on day 7 post heterotopic trachea transplantation...
August 29, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28862101/efficient-use-of-a-limited-resource-femoral-head-allograft-a-comparison-of-allograft-preparation-methods
#17
Timothy Marshall, Jason Chow, Brahman Sivakumar, Nushin Ahmed, Paul Smith
PURPOSE: The purpose of the study was to compare the yield and compressed volume of femoral head allograft prepared by either hand morselization or a bone mill. METHODS: Twenty human femoral head allografts were donated from a bone bank and morselized by two different methods. The heads were divided in half and split into two sample groups. One group underwent hand morselization with large bone nibblers, while the other was prepared using a bone mill. The volume of graft produced was measured...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28860398/revision-anatomical-reconstruction-of-the-lateral-ligaments-of-the-ankle-augmented-with-suture-tape-for-patients-with-a-failed-brostr%C3%A3-m-procedure
#18
B K Cho, Y M Kim, S M Choi, H W Park, N F SooHoo
AIMS: The aim of this prospective study was to evaluate the intermediate-term outcomes after revision anatomical ankle ligament reconstruction augmented with suture tape for a failed modified Broström procedure. PATIENTS AND METHODS: A total of 30 patients with persistent instability of the ankle after a Broström procedure underwent revision augmented with suture tape. Of these, 24 patients who were followed up for more than two years were included in the study...
September 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28856347/a-new-option-for-glenoid-reconstruction-in-recurrent-anterior-shoulder-instability
#19
Mia Smucny, Anthony Miniaci
Anteroinferior glenoid bone loss plays a significant role in recurrent glenohumeral instability. Surgical strategies for reconstructing the glenoid in these cases include coracoid transfer, iliac crest autograft, and allograft (osteochondral and iliac crest). In this article, we report on a new technique for managing glenoid bone loss, preshaped allograft, and describe surgical technique and outcomes. So far we have implanted this allograft in 15 patients, and at short-term follow-up there are no known cases of recurrent instability or graft resorption...
July 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28856336/effect-of-canine-cortical-bone-demineralization-on-osteogenic-differentiation-of-adipose-derived-mesenchymal-stromal-cells
#20
Kwangrae Jo, Yongsun Kim, Seung Hoon Lee, Yong Seok Yoon, Wan Hee Kim, Oh-Kyeong Kweon
Demineralized bone allografts and mesenchymal stromal cells have been used to promote bone regeneration. However, the degree to which cortical bone should be demineralized for use in combination with adipose-derived mesenchymal stromal cells (Ad-MSCs) remains to be clarified. In this study, the in vitro osteogenic ability of Ad-MSCs on allografts was investigated in relation to the extent of demineralization. Three treatment groups were established by varying exposure time to 0.6 N HCL: partially demineralized (PDB; 12 h), fully demineralized (FDB; 48 h), and non-demineralized bone (NDB; 0 h, as a control)...
August 2017: Heliyon
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