Eleanor Brindle, Lorraine Lillis, Rebecca Barney, Pooja Bansil, Sonja Y Hess, K Ryan Wessells, Césaire T Ouédraogo, Francisco Arredondo, Mikaela K Barker, Neal E Craft, Christina Fischer, James L Graham, Peter J Havel, Crystal D Karakochuk, Mindy Zhang, Ei-Xia Mussai, Carine Mapango, Jody M Randolph, Katherine Wander, Christine M Pfeiffer, Eileen Murphy, David S Boyle
A lack of comparative data across laboratories is often a barrier to the uptake and adoption of new technologies. Furthermore, data generated by different immunoassay methods may be incomparable due to a lack of harmonization. In this multicenter study, we describe validation experiments conducted in a single lab and cross-lab comparisons of assay results to assess the performance characteristics of the Q-plex™ 7-plex Human Micronutrient Array (7-plex), an immunoassay that simultaneously quantifies seven biomarkers associated with micronutrient (MN) deficiencies, inflammation and malarial antigenemia using plasma or serum; alpha-1-acid glycoprotein, C-reactive protein, ferritin, histidine-rich protein 2, retinol binding protein 4, soluble transferrin receptor, and thyroglobulin...
2021: PloS One