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Oncology pharmacist

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https://www.readbyqxmd.com/read/29651918/updated-report-on-incidence-of-infusion-site-reactions-associated-with-peripheral-intravenous-administration-of-fosaprepitant
#1
Eric Chau, Jordan Lundberg, Gary Phillips, Michael Berger, Robert Wesolowski
Purpose Fosaprepitant (Emend®) is an antiemetic frequently used for the prevention of chemotherapy-induced nausea and vomiting. We previously documented an overall 28.7% incidence of infusion-site reactions in patients receiving fosaprepitant via peripheral venous access. These data resulted in a practice change within our institution; fosaprepitant is administered in more dilute concentrations over 30 min to prevent these adverse events. This retrospective study explored the impact of this practice change on the incidence of infusion-site reactions...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29621893/facilitating-home-hospice-transitions-of-care-in-oncology-evaluation-of-clinical-pharmacists-interventions-hospice-program-satisfaction-and-patient-representation-rates
#2
Alison P Duffy, Nina M Bemben, Jueli Li, James Trovato
BACKGROUND: The importance of medication reconciliation and the pharmacist's role within the interdisciplinary team at the point of transition to home hospice is understudied. A transitions of care pilot initiative was developed to streamline the transition for patients at end of life from inpatient cancer center care to home hospice. The initiative consisted of using a hospice discharge checklist, pharmacist-led discharge medication reconciliation in consultation with the primary team responsible for inpatient care, review of discharge prescriptions, and facilitation of bedside delivery of discharge medications...
January 1, 2018: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/29587608/a-pilot-study-to-assess-the-pharmacy-impact-of-implementing-a-chemotherapy-induced-nausea-or-vomiting-collaborative-disease-therapy-management-in-the-outpatient-oncology-clinics
#3
Kasey Jackson, Cathy Letton, Andy Maldonado, Andrew Bodiford, Amy Sion, Rebekah Hartwell, Anastasia Graham, Carolyn Bondarenka, Lynn Uber
Background Collaborative drug therapy management is a formal partnership between a pharmacist and physician to allow the pharmacist to manage a patient's drug therapy. Literature supports collaborative disease therapy management can improve patient outcomes, improve medication adherence, enhance medication safety, and positively influence healthcare expenditures. Chemotherapy induced nausea or vomiting is considered one of the most distressing and feared adverse events among patients receiving chemotherapy...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29548299/severe-immune-mucositis-and-esophagitis-in-metastatic-squamous-carcinoma-of-the-larynx-associated-with-pembrolizumab
#4
Fanny Zulay Acero Brand, Nicolas Suter, Jean-Philippe Adam, Bernard Faulques, Antonio Maietta, Denis Soulières, Normand Blais
BACKGROUND: Pembrolizumab is an anti-programmed death 1 (PD-1) receptor monoclonal antibody that has shown activity as second line treatment for metastatic head and neck squamous cell carcinoma (HNSCC). Immune-related adverse events are now well described complications of PD-1 inhibitors and most organ sites have been shown to be potentially affected. CASE PRESENTATION: We describe a 69-year old patient with a relapsed squamous cell carcinoma of the supraglottic larynx with lung metastasis after receiving adjuvant concurrent cisplatin and radiotherapy...
March 16, 2018: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/29518017/adherence-to-oral-anticancer-medications-evolving-interprofessional-roles-and-pharmacist-workforce-considerations
#5
Gennaro A Paolella, Andrew D Boyd, Scott M Wirth, Sandra Cuellar, Neeta K Venepalli, Stephanie Y Crawford
Interprofessional care is exhibited in outpatient oncology practices where practitioners from a myriad of specialties (e.g., oncology, nursing, pharmacy, health informatics and others) work collectively with patients to enhance therapeutic outcomes and minimize adverse effects. Historically, most ambulatory-based anticancer medication therapies have been administrated in infusion clinics or physician offices. Oral anticancer medications (OAMs) have become increasingly prevalent and preferred by patients for use in residential or other non-clinic settings...
March 8, 2018: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29516505/methadone-against-cancer-lost-in-translation
#6
REVIEW
Dirk Theile, Gerd Mikus
Recently, the opioid analgesic D,L-methadone has gained much attention as a potential antineoplastic compound, considerably triggered through lay press and media. In consequence, physicians and pharmacists are currently confronted with numerous patients willing to use D,L-methadone against their malignancies. Well-performed in vitro and in vivo models have in fact shown pro-apoptotic effects of D,L-methadone or other opioids, but also proliferation-stimulating properties. Moreover, the mechanisms of proposed opioid-stimulated apoptosis are incompletely described or contradicting...
March 8, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29506968/the-impact-of-a-small-private-online-course-as-a-new-approach-to-teaching-oncology-development-and-evaluation
#7
Charlotte Vaysse, Elodie Chantalat, Odile Beyne-Rauzy, Louise Morineau, Fabien Despas, Jean-Marc Bachaud, Nathalie Caunes, Muriel Poublanc, Elie Serrano, Roland Bugat, Marie-Eve Rougé Bugat, Anne-Laure Fize
BACKGROUND: Oncology involves complex care and multidisciplinary management of patients; however, misinformation and ineffective communication remain problematic. OBJECTIVE: The educational objective of our study was to develop a new teaching method to improve cancer treatment and management by emphasizing the link between hospitals (inpatients) and their surrounding communities (outpatients). METHODS: A team of 22 professionals from public and private institutions developed a small private online course (SPOC)...
March 5, 2018: JMIR Medical Education
https://www.readbyqxmd.com/read/29499998/-implementation-of-a-remote-oncology-monitoring-program-for-cancer-patients-in-outpatient-care-unit-a-major-challenge-for-the-different-actors
#8
Elodie Peyrilles, Coralie Lepage-Seydoux, Karine Sejean, Brigitte Bonan
INTRODUCTION: The development of outpatient departments requires health professionals to reorganize practices for a better patient monitoring and a better patient care pathway. OBJECTIVE: To evaluate, using indicators, the impact of an oncology-monitoring program on activity and organizational fluidity in a Cytotoxic Preparation Unit and clinical departments. Method the clinical and biological data are collected between two injections by calling the patient two days prior chemotherapy is performed by a specialist nurse of an outsourced medical call center...
February 27, 2018: Bulletin du Cancer
https://www.readbyqxmd.com/read/29492103/awareness-and-compliance-with-pharmacovigilance-requirements-amongst-uk-oncology-healthcare-professionals
#9
Rebecca J Thorne, Rosanne J Bruggink, Stephen J Kelly, Sarah Jl Payne, Simon J Purcell, David A Montgomery
Since 2013, once a medicine receives marketing authorisation in the European Union, it is labelled with an inverted black triangle indicating all adverse reactions should be reported. Our aim was to explore understanding of the black triangle and compliance with adverse event (AE) reporting requirements by UK oncology healthcare professionals (HCPs). A questionnaire was electronically distributed to oncology pharmacists (P) via the British Oncology Pharmacy Association, to oncologists (O) through the Association of Cancer Physicians and also to nurses (N) via the UK Oncology Nursing Society...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29486920/-what-are-the-expectations-of-coordination-and-accompaniment-of-french-patients-with-cancer-towards-their-community-pharmacist
#10
Guillaume Hébert, Etienne Minvielle, Mario Di Palma, François Lemare
PURPOSES: Analyze the relationship and expectations of cancer patients towards the community pharmacist in a pharmaceutical care coordination project. METHODS: In November 2014, a questionnaire was distributed to ambulatory patients of a university hospital specialized in oncology. Thirteen questions explored the consumption habits and the usage of the pharmacy (typology of consumers, use of goods and benefits consumed), and collected their expectations for pharmaceutical benefits in the context of the management of their cancer...
February 24, 2018: Bulletin du Cancer
https://www.readbyqxmd.com/read/29485752/development-of-consensus-on-models-of-care-in-adults-with-intestinal-failure-using-a-modified-delphi-approach
#11
Sharon Carey, Michelle Kalachov, Lynn Jones, Cherry Koh
BACKGROUND AND AIM: To establish consensus on service delivery models for management of Type III intestinal failure (IF) and home parenteral nutrition (HPN) within the Australian health care system and to identify barriers and enablers in moving towards this ideal model. METHODS: A modified Delphi methodology was utilised to survey experts working in Type III IF HPN. The panel comprised physicians, dietitians, nurses and pharmacists from 18 of the 20 adult Type III IF HPN centres across Australia...
February 27, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29481295/medication-safety-in-oncology-care-mapping-checking-procedures-from-prescription-to-administration-of-chemotherapy
#12
Yvonne Pfeiffer, Stephan S Gut, David L B Schwappach
PURPOSE: To increase medication safety in oncology, checking procedures are increasingly applied by nurses, physicians, and pharmacists. However, little is known about the number, types, and consistency of implemented checks. The aim of the study was to assess the number and types of different checking procedures that are performed along the lifecycle of a chemotherapy prescription across three hospitals, different care settings, administration routes, and professional groups. METHODS: A scheme to evaluate checking procedures and a mapping approach to illustrate the checks along the phases of the medication process were developed...
February 26, 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29460703/practice-insights-on-patient-care-management-overview-for-chemoradiation-toxic-mucositis-guidelines-guideline-supported-therapies-and-high-potency-polymerized-cross-linked-sucralfate-prothelial
#13
Ricky W McCullough
Aim To offer a practice insight for the management of chemoradiation toxic mucositis. Method Review chemoradiation toxic mucositis, its pathobiology and breadth of symptom presentation. Review mucositis guidelines and guideline-supported anti-mucositis therapies. Offer guidance on guidelines and an abbreviated review of high potency cross-linked sucralfate for management of chemoradiation toxic mucositis. Result There are six major mucositis guidelines but only one that is current and regularly updated. Guidelines from the Multinational Association Supportive Cancer Care suggest 14 interventions gleaned from controlled trials, 12 of which are off-label uses of therapies that offer statistically significant but incrementally beneficial outcomes...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29451420/integration-of-clinical-pharmacists-into-an-ambulatory-pediatric-hematology-oncology-transplant-clinic
#14
Kimberly D Defoe, Jennifer Jupp, Tara Leslie
Objectives To describe key activities performed by a newly deployed clinical pharmacist in an outpatient pediatric hematology, oncology, transplant clinic. To demonstrate how utilization of the pharmacist evolved, as indicated by changes in frequency of key activities, during the first four months of integration. Design Clinical pharmacists were made consistently available in an outpatient clinic serving hematology, oncology, transplant patients and their families. A list of key activities, based on provincial clinical pharmacist standards, was created to provide a framework for the role...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29446003/development-of-a-ready-to-use-tool-that-includes-preventability-for-the-assessment-of-adverse-drug-events-in-oncology
#15
Guillaume Hébert, Florence Netzer, Sylvain Landry Kouakou, François Lemare, Etienne Minvielle
Background Adverse drug events (ADEs) occur frequently in oncology and justify continuous assessment and monitoring. There are several methods for detecting them, but the trigger tool method seems the most appropriate. Although a generic tool exists, its use for ADEs in oncology has not been convincing. The development of a focused version is therefore necessary. Objective To provide an oncology-focused trigger tool that evaluates the prevalence, harm, and preventability in a standardised method for pragmatic use in ADE surveillance...
February 14, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29400987/dose-rounding-of-biologic-and-cytotoxic-anticancer-agents-a-position-statement-of-the-hematology-oncology-pharmacy-association
#16
Rebecca Fahrenbruch, Polly Kintzel, Anne Marie Bott, Steven Gilmore, Ryan Markham
PURPOSE: To present a position statement from the Hematology/Oncology Pharmacy Association (HOPA) that pertains to dose rounding of biologic and cytotoxic anticancer agents. METHODS: The HOPA Standards Committee organized a work group of oncology pharmacist specialists to examine the safety and value of dose rounding of biologic and cytotoxic anticancer agents. Primary literature that describes methods for dose rounding, with clinical or economic data, were analyzed...
February 5, 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29375887/a-questionnaire-survey-of-pharmacists-regarding-the-clinical-practice-guidelines-for-the-appropriate-use-of-granulocyte-colony-stimulating-factors
#17
Tetsuya Sasaki, Yasuhisa Kato, Atsushi Sato, Noriko Usui, Eishi Baba, Toshimi Takano, Nobuyuki Susumu, Kazunori Ohnishi, Hitomi Nishimoto, Katsuyuki Kiura
Background: Clinical practice guidelines should be user-friendly and confirming their penetration rate and compliance are critical. Methods: We conducted a nationwide web-based questionnaire survey among pharmacists regarding the 2013 guidelines for the appropriate use of granulocyte-colony stimulating factors (G-CSFs) (version 2, published by the Japan Society of Clinical Oncology [JSCO]) between August 24 and September 6, 2015. Results: A total of 301 pharmacists responded; 96...
2018: Journal of Pharmaceutical Health Care and Sciences
https://www.readbyqxmd.com/read/29375014/impact-of-a-formal-pharmacist-run-oral-antineoplastic-monitoring-program-a-pilot-study-in-an-adult-genitourinary-oncology-clinic
#18
Brette Conliffe, Lindsay Figg, Padmini Moffett, Leslie Lauterwasser, Laura Beth Parsons
Background In recent years, there has been a changing paradigm in the management of oncologic disease states from the use of intravenous therapies, requiring a visit to the infusion center or hospitalization, to new therapies that can be administered orally.1,2 Several publications have evaluated the role pharmacists may play in the initial prescribing of oral chemotherapy, however the impact of a formalized pharmacist follow-up program has not been well defined. This study evaluates the impact of a pilot pharmacist-run oral antineoplastic monitoring program...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29353396/the-differences-in-the-assessments-of-side-effects-at-an-oncology-outpatient-clinic
#19
A Bayraktar-Ekincioglu, E Kucuk
Background There is a growing interest in the use of targeted and immunotherapies in oncology. However, the assessment of side effects can be different due to interpretation of patients' health status by healthcare professionals in oncology outpatient clinics. Objective To demonstrate the differences in the assessments of side effects conducted independently by a clinical pharmacist and nurses in patients who receive targeted therapies at an oncology outpatient clinic. Setting The study was conducted at the University Oncology Hospital in an outpatient clinic from October 2015 to March 2016...
January 20, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29351371/implementation-of-standardized-clinical-processes-for-tpmt-testing-in-a-diverse-multidisciplinary-population-challenges-and-lessons-learned
#20
Kristin W Weitzel, D Max Smith, Amanda R Elsey, Benjamin Q Duong, Benjamin Burkley, Michael Clare-Salzler, Yan Gong, Tara A Higgins, Benjamin Kong, Taimour Langaee, Caitrin W McDonough, Benjamin J Staley, Teresa T Vo, Dyson T Wake, Larisa H Cavallari, Julie A Johnson
Although thiopurine S-methyltransferase (TPMT) genotyping to guide thiopurine dosing is common in the pediatric cancer population, limited data exist on TPMT testing implementation in diverse, multidisciplinary settings. We established TPMT testing (genotype and enzyme) with clinical decision support, provider/patient education, and pharmacist consultations in a tertiary medical center and collected data over 3 years. During this time, 834 patients underwent 873 TPMT tests (147 (17%) genotype, 726 (83%) enzyme)...
March 2018: Clinical and Translational Science
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