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Oncology pharmacy

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https://www.readbyqxmd.com/read/29157148/implementation-of-clinical-pharmacy-services-in-an-academic-oncology-practice-in-india
#1
Himanshu Patel, Parthasarathi Gurumurthy
Objective This study was conducted to investigate medication-related problems after implementation of clinical pharmacy services at a speciality oncology care setting. Methods It was a prospective interventional study conducted for a period of three years at a private academic oncology care setting. Paper-based medical records and medication orders were reviewed and patients and care givers were interviewed to understand the treatment plan. All the medication-related problems were identified by clinical pharmacists by performing drug therapy review...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29143916/a-real-world-comparison-of-folfirinox-gemcitabine-plus-nab-paclitaxel-and-gemcitabine-in-advanced-pancreatic-cancers
#2
Ying Wang, Pierre Camateros, Winson Y Cheung
PURPOSE: FOLFIRINOX (FFN), nab-paclitaxel plus gemcitabine (GN), and gemcitabine are three systemic therapies that provide clinically meaningful benefit to patients with unresectable pancreatic cancer (UPC). There are no clinical trials that directly compare the efficacy of all three regimens. In this study, we aim to examine and compare the real-world effectiveness of these treatments. METHODS: Patients diagnosed with UPC who initiated palliative chemotherapy from August 2014 to January 2016 at any one of six cancer centers in British Columbia were identified from the provincial pharmacy...
November 16, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29112581/instituting-vincristine-minibag-administration-an-innovative-strategy-using-simulation-to-enhance-chemotherapy-safety
#3
Nancy Corbitt, Lisa Malick, Jennifer Nishioka, Ann Rigdon, Stephanie Szoch, Peggy Torr
The first fatal incident of wrong-route administration of vinca alkaloids occurred in 1968. Initial recommendations for practice change occurred in 2005. In 2012, 54% of oncology treatment sites had changed their practice. The authors' institution has developed a safe, adaptable, and consistent process to prepare, deliver, and administer vinca alkaloids by means of a minibag delivery. A multidisciplinary team, including representatives from the nursing and pharmacy departments, reviewed the literature and developed all processes, including staff education...
November 2017: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/29112494/proposal-for-the-creation-of-a-national-strategy-for-precision-medicine-in-cancer-a-position-statement-of-seom-seap-and-sefh
#4
Pilar Garrido, Azucena Aldaz, Miguel Ángel Calleja, Enrique De Álava, María Jesús Lamas, Miguel Martín, Xavier Matías-Guiu, José Palacios, Ruth Vera
Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming clinical and biomedical research, as well as health care itself from a conceptual, as well as a methodological viewpoint, providing extraordinary opportunities to improve public health and lower the costs of the healthcare system. However, the implementation of precision medicine poses ethical-legal, regulatory, organizational and knowledge-related challenges...
November 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/29078708/a-clinical-pharmacy-pilot-within-a-precision-medicine-program-for-cancer-patients-and-review-of-related-pharmacist-clinical-practice
#5
Justin R Arnall, Robin Petro, Jai N Patel, LeAnne Kennedy
Purpose The implementation, benefits, and challenges of clinical pharmacist services within a Precision Medicine Program for cancer patients are described. By relating the practice model that was developed, this report may further encourage pharmacists at cancer centers nationally to be involved and lead precision-based care in the oncology setting. Summary A clinical pharmacist was integrated into a Precision Medicine Program for oncology patients using somatic testing to identify actionable mutations and apply targeted therapy to malignancies...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29078707/continuous-care-provided-through-comprehensive-medication-management-in-an-acute-care-practice-model
#6
T David Marr, Nicole R Pinelli, Jamie A Jarmul, Kayla M Waldron, Stephen F Eckel, Jonathan D Cicci, Jill S Bates, Lindsey B Amerine
BACKGROUND: Pharmacy practice models that foster pharmacists' accountability for medication-related outcomes are imperative for the profession. Comprehensive medication management (CMM) is an opportunity to advance patient care. OBJECTIVE: The objective of this study was to evaluate the impact of a CMM practice model in the acute care setting on organizational, patient, and financial outcomes. METHODS: Three adult service lines focused on at-risk patients identified using internal risk stratification methodology were implemented...
October 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29059028/introduction-of-a-dose-banding-system-for-parenteral-chemotherapy-on-a-haematology-oncology-day-ward
#7
Caoimhe E O'Leary, Aisling Collins, Martin C Henman, Fionnuala King
Introduction The increasing incidence of cancer and the finite capacity of hospital aseptic compounding units pose a serious challenge to the provision of cancer care. Chemotherapy dose-banding is a method of rationalising parenteral chemotherapy dosing and supply, whereby patient-individualised doses are rounded to predetermined banded doses. The banded doses may be outsourced as stock items which increases the supply capacity of the aseptic compounding unit. Methods Kotter's 8-step change management model was used to structure the implementation of dose-banding of 5-fluorouracil 46-h infusers on the haematology-oncology day ward in St...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29043569/nutritional-support-and-parenteral-nutrition-in-cancer-patients-an-expert-consensus-report
#8
REVIEW
J A Virizuela, M Camblor-Álvarez, L M Luengo-Pérez, E Grande, J Álvarez-Hernández, M J Sendrós-Madroño, P Jiménez-Fonseca, M Cervera-Peris, M J Ocón-Bretón
BACKGROUND: Malnutrition is a frequent medical problem of cancer patients that negatively impacts their quality of life. METHODS: A multidisciplinary group of experts in Medical Oncology, Pharmacy, and Nutrition convened to discuss the management of the nutritional support in cancer patients. RESULTS: Of the 18 questions addressed, 9 focused on nutritional support, 5 were related to parenteral nutrition (PN) and 4 about home PN (HPN). The panel of experts recommends using nutritional screening routinely, at diagnosis and throughout the disease course, for detecting the risk of malnutrition and, if it is positive, to perform a complete nutritional assessment, to diagnose malnutrition...
October 17, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29020857/optimizing-patient-education-of-oncology-medications-a-descriptive-survey-of-pharmacist-provided-patient-education-in-canada
#9
Gillian Donald, Samantha Scott, Larry Broadfield, Claudia Harding, Andrea Meade
Background The incidence of cancer is increasing in Canada due to an aging and growing population. This frequently necessitates chemotherapy, which is a high-risk treatment, often given as a part of a complex regimen with serious side effects. A review of the evidence of pharmacy-provided patient education initiatives targeted to oncology patients revealed that minimal is known about this service. Objective The objective of this study was to determine the different models of patient education of oncology medications delivered by pharmacists to adult oncology patients in a hospital or cancer center in Canada...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28976446/the-pharmacological-costs-of-second-line-treatments-for-recurrent-ovarian-cancer
#10
Jacopo Giuliani, Andrea Bonetti
INTRODUCTION: In ovarian cancer, it is uncertain which chemotherapy regimen is more clinically effective and cost-effective for the treatment of recurrence; therefore, it might be interesting to make a balance between the cost of the drugs administered and the difference in progression-free survival (PFS) and overall survival (OS). METHODS: The present evaluation was restricted to pivotal phase 3 randomized controlled trials. We calculated the pharmacological costs necessary to get the benefit in PFS and OS...
November 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28964384/prevention-and-treatment-of-cancer-associated-thrombosis-in-france-a-national-survey-among-vascular-disease-and-supportive-care-specialists
#11
I Mahé, F Scotté, J-B Rey, I Elalamy, A Lamblin, D Mayeur, G Pernod
BACKGROUND/AIM: Long-term use of low-molecular-weight heparins (LMWH) for the treatment of cancer-associated thrombosis (CAT) has been well-established. Conversely, the use of thromboprophylaxis in patients with cancer remains controversial in the absence of homogeneous guidelines. Our aim was to assess the awareness of treatment guidelines and the management of patients with CAT in daily clinical practice. METHODS: A national survey based on an open questionnaire developed by a panel of health professionals including specialists in vascular medicine, oncology, supportive care and pharmacy, was proposed on line to 2104 specialists experts in the management of CAT with the objective to collect at least 400 answers...
October 2017: J Med Vasc
https://www.readbyqxmd.com/read/28947527/impact-of-clinical-pharmacists-in-outpatient-oncology-practices-a-review
#12
Justin Gatwood, Katie Gatwood, Ezra Gabre, Maurice Alexander
PURPOSE: Published literature describing the effectiveness of outpatient oncology services delivered by clinical pharmacists is summarized. METHODS: Peer-reviewed articles on studies evaluating the provision of outpatient oncology services by licensed clinical pharmacists in the United States were identified and screened according to a study-specific protocol. Only research publications focused on the care of oncology patients and indicating the evaluation of measurable services and outcomes were selected for review...
October 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28944733/performance-based-risk-sharing-arrangements-for-pharmaceutical-products-in-the-united-states-a-systematic-review
#13
Justin S Yu, Lauren Chin, Jennifer Oh, Jorge Farias
BACKGROUND: Value for money is a growing necessity in today's U.S. health care system in which drug spending is expected to increase by an average rate of 6.7% yearly through 2025. In response to uncertainty about real-world clinical and economic outcomes for many drugs, health insurers and pharmacy benefit managers (PBMs) have implemented various contracts and arrangements with drug manufacturers that can collectively be described as performance-based risk-sharing arrangements (PBRSAs)...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28942722/pharmacy-workload-benchmarking-establishing-a-health-system-outpatient-infusion-productivity-metric
#14
Jeffrey S Reichard, David M Garbarz, Amanda L Teachey, Jonathan Allgood, M Jay Brown
Background and objectives Current productivity assessment models lack the ability to measure the quality of pharmacy services through workload validation. The goal of our efforts was to create a model to more accurately assess workload at multiple outpatient infusion centers. Method Current procedural terminology codes were identified as representative of the key drivers of pharmacy workload. Fourteen current procedural terminology codes representing medication orders were selected and categorized into eight distinctive groups associated with varying amounts of pharmacy workload...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28898593/biosimilars-implications-for-clinical-practice
#15
Robert M Rifkin, Susan R Peck
In 2015, the United States Food and Drug Administration (FDA) approved the first biosimilar, filgrastim-sndz, a biosimilar of the granulocyte colony-stimulating factor filgrastim. Since that time, the FDA has approved four additional biosimilar tumor necrosis factor α inhibitors, and, in May 2017, the Oncology Drug Advisory Committee voted in favor of approval of an epoetin alfa biosimilar. The patents of several widely used biologic cancer therapies (including trastuzumab, rituximab, bevacizumab, cetuximab, and pegfilgrastim) are recently expired or due to expire in the near future, so the introduction of biosimilars into the oncology treatment armamentarium is imminent...
September 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28861725/proposal-for-the-creation-of-a-national-strategy-for-precision-medicine-in-cancer-a-position-statement-of-seom-seap-and-sefh
#16
P Garrido, A Aldaz, R Vera, M A Calleja, E de Álava, M Martín, X Matías-Guiu, J Palacios
Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming clinical and biomedical research, as well as health care itself from a conceptual, as well as a methodological viewpoint, providing extraordinary opportunities to improve public health and lower the costs of the healthcare system. However, the implementation of precision medicine poses ethical-legal, regulatory, organizational, and knowledge-related challenges...
August 31, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28841101/implementation-and-evaluation-of-medicine-and-therapeutic-information-service-by-clinical-pharmacists-in-oncology-care-setting
#17
Himanshu Patel, Parthasarathi Gurumurthy
Background This study was conducted to explore the role of clinical pharmacists in providing medicine and therapeutic information service in oncology care setting. Methods It was a prospective study conducted for a period of three years after implementation of medicine and therapeutic information service as an integral part of oncology pharmacy services. The medicine and therapeutic information queries were received during ward rounds, at ambulatory care and via telephone by clinical pharmacists. All the medicine and therapeutic information requests were reviewed and answered to the concerned requester(s)...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28841099/survey-of-guidelines-and-current-practices-for-safe-handling-of-antineoplastic-and-other-hazardous-drugs-used-in-24-countries
#18
Patricia I Mathias, Barbara A MacKenzie, Christine A Toennis, Thomas H Connor
Purpose A survey of guidelines and current practices was conducted to examine the safe handling procedures for antineoplastic and other hazardous drugs that are used in 24 countries including the Americas, Europe, the Mideast, Far East, and Australia. Methods Subject experts were asked to complete a brief survey regarding safe handling guidelines and practices for hazardous drugs in their countries. Questions addressed practices for handling monoclonal antibodies, the use of closed-system transfer devices, medical surveillance practices, and measurements of compliance with existing guidelines...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28812473/implementation-of-a-pathway-for-the-treatment-of-fever-and-neutropenia-in-pediatric-patients-with-cancer
#19
Joy Vanderway, Catherine Vincent, Susan M Walsh, Jennifer Obrecht
Fever and neutropenia is an oncologic emergency. Time-to-antibiotics (TTA) refers to the amount of time from initial provider evaluation for fever and neutropenia to intravenous antibiotic administration. Research supports that rapid time-to-antibiotics (RTTA) is associated with improved patient outcomes. This quality improvement project evaluated the success of implementing an RTTA pathway in pediatric oncology patients with fever and neutropenia. The setting was an advanced practice nurse-managed pediatric ambulatory infusion center where patients with fever and neutropenia were often evaluated and treated...
September 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/28804149/capecitabine-oxaliplatin-and-bevacizumab-bcapox-regimen-for-metastatic-colorectal-cancer
#20
Meghan J Garrett, J Aubrey Waddell, Dominic A Solimando
The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases. Questions or suggestions for topics should be addressed to Dominic A. Solimando, Jr, President, Oncology Pharmacy Services, Inc, 4201 Wilson Blvd #110-545, Arlington, VA 22203, e-mail: OncRxSvc@comcast...
May 2017: Hospital Pharmacy
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