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Oncology pharmacy

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https://www.readbyqxmd.com/read/27922797/potential-obstacles-in-the-acquisition-of-oral-anticancer-medications
#1
Jennifer L Niccolai, Danielle L Roman, Justin M Julius, Rachelle W Nadour
PURPOSE: To determine the amount of time elapsed between prescriber order and patient receiving oral anticancer medication. PATIENTS AND METHODS: Adult patients with a diagnosis of cancer were prospectively identified in three outpatient oncology clinics when oral anticancer agents were prescribed during a 4-month observation period. For each patient, time to obtain medication was analyzed by the following time points: date of prescription, date of submission to insurance, date prior authorization was obtained, date financial assistance was received, date prescription was processed by pharmacy, and date patient received medication...
December 6, 2016: Journal of Oncology Practice
https://www.readbyqxmd.com/read/27919878/pharmacy-residency-training-measured-through-a-standardized-knowledge-test
#2
Amy N Thompson, Brian P McKinzie, Jason S Haney, Jean M Nappi, Nicole Pilch
PURPOSE: The use of a standardized knowledge test to assess postgraduate year 1 (PGY1) pharmacy residency training was evaluated. METHODS: This was a retrospective review of a prospectively administered exam. A bank of questions was developed by preceptors from each of the core rotation disciplines: general medicine (including ambulatory care and oncology), pediatrics, critical care (including transplantation), drug information, operations, practice management, and psychiatry...
December 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27919308/outbreak-of-pantoea-agglomerans-bloodstream-infections-at-an-oncology-clinic-illinois-2012-2013
#3
Brian R Yablon, Raymund Dantes, Victoria Tsai, Rachel Lim, Heather Moulton-Meissner, Matthew Arduino, Bette Jensen, Megan Toth Patel, Michael O Vernon, Yoran Grant-Greene, Demian Christiansen, Craig Conover, Alexander Kallen, Alice Y Guh
OBJECTIVE To determine the source of a healthcare-associated outbreak of Pantoea agglomerans bloodstream infections. DESIGN Epidemiologic investigation of the outbreak. SETTING Oncology clinic (clinic A). METHODS Cases were defined as Pantoea isolation from blood or catheter tip cultures of clinic A patients during July 2012-May 2013. Clinic A medical charts and laboratory records were reviewed; infection prevention practices and the facility's water system were evaluated. Environmental samples were collected for culture...
December 6, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27864201/precision-medicine-in-oncology-new-practice-models-and-roles-for-oncology-pharmacists
#4
Christine Walko, Patrick J Kiel, Jill Kolesar
PURPOSE: Three different precision medicine practice models developed by oncology pharmacists are described, including strategies for implementation and recommendations for educating the next generation of oncology pharmacy practitioners. SUMMARY: Oncology is unique in that somatic mutations can both drive the development of a tumor and serve as a therapeutic target for treating the cancer. Precision medicine practice models are a forum through which interprofessional teams, including pharmacists, discuss tumor somatic mutations to guide patient-specific treatment...
December 1, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27855948/-data-regarding-the-roles-and-impact-of-pharmaceutical-activities-quantitative-and-qualitative-study-with-four-groups-of-experts
#5
M Breton, E Ferreira, N Letarte, J-F Bussières
OBJECTIVES: The use of scientific data about the roles and the impact of pharmacists is suboptimal. The objective is to evaluate the opinion and attitude of expert pharmacists on the measurement of indicators for the pharmaceuticals activities, sharing and appropriation of scientific knowledge and the place of the website "Impact Pharmacie". METHODS: This is a descriptive cross-sectional study. Four expert groups were interviewed (hematology-oncology, intensive care, emergency and infectious diseases)...
November 14, 2016: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/27845870/differences-in-health-care-use-and-costs-among-patients-with-cancer-receiving-intravenous-chemotherapy-in-physician-offices-versus-in-hospital-outpatient-settings
#6
Maxine D Fisher, Rajeshwari Punekar, Yeun Mi Yim, Arthur Small, Joseph R Singer, Jay Schukman, Barbara L McAneny, Rakesh Luthra, Jennifer Malin
PURPOSE: The current shift in site of care from community oncology practices to the hospital outpatient department to deliver oncology services may have significant implications for the economic and clinical outcomes of cancer care. Therefore, this study compares health care use and costs among patients with cancer receiving intravenous (IV) chemotherapy in physician offices (PO) versus in hospital outpatient settings (HOP). METHODS: This retrospective study, which was based on medical and pharmacy claims data, included patients (age, 18 to 64 years) initiating IV chemotherapy/biologic treatment between January 1, 2006, and August 31, 2012, who were diagnosed with early or metastatic breast cancer, metastatic lung cancer, metastatic colorectal cancer, or non-Hodgkin lymphoma or chronic lymphocytic leukemia...
November 15, 2016: Journal of Oncology Practice
https://www.readbyqxmd.com/read/27803501/medication-therapy-management-for-patients-receiving-oral-chemotherapy-agents-at-a-community-oncology-center-a-pilot-study
#7
Nathan S Bertsch, Ross J Bindler, Poppy L Wilson, Anne P Kim, Beverly Ward
Purpose: To determine the impact of a pharmacist-driven medication therapy management (MTM) program for patients receiving oral chemotherapy agents. Methods: We assessed the impact of MTM consultations with a pharmacist for patients who were receiving a new prescription for an oral chemotherapy agent. Data were assessed for outcomes including (1) number of medication errors identified in electronic medical records (EMRs), (2) number of interventions performed by the pharmacist, (3) time spent on the MTM process, and (4) patient satisfaction...
October 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27799608/multicenter-study-of-environmental-contamination-with-cyclophosphamide-ifosfamide-and-methotrexate-in-48-canadian-hospitals
#8
Céline Poupeau, Cynthia Tanguay, Nicolas J Caron, Jean-François Bussières
CONTEXT: Oncology workers are occupationally exposed to antineoplastic drugs. This exposure can induce adverse health effects. In order to reduce their exposure, contamination on surfaces should be kept as low as possible. OBJECTIVES: To monitor environmental contamination with cyclophosphamide, ifosfamide, and methotrexate in oncology pharmacy and patient care areas in Canadian hospitals. To describe the impact of some factors that may limit contamination. METHODS: This is a descriptive study...
October 31, 2016: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/27733666/the-impacts-of-a-pharmacist-managed-outpatient-clinic-and-chemotherapy-directed-electronic-order-sets-for-monitoring-oral-chemotherapy
#9
Brandon Battis, Linda Clifford, Mostaqul Huq, Edrick Pejoro, Scott Mambourg
OBJECTIVES: Patients treated with oral chemotherapy appear to have less contact with the treating providers. As a result, safety, adherence, medication therapy monitoring, and timely follow-up may be compromised. The trend of treating cancer with oral chemotherapy agents is on the rise. However, standard clinical guidance is still lacking for prescribing, monitoring, patient education, and follow-up of patients on oral chemotherapy across the healthcare settings. The purpose of this project is to establish an oral chemotherapy monitoring clinic, to create drug and lab specific provider order sets for prescribing and lab monitoring, and ultimately to ensure safe and effective treatment of the veterans we serve...
October 12, 2016: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/27729673/gefitinib-and-sonidegib
#10
EDITORIAL
Corey J Medler, J Aubrey Waddell, Dominic A Solimando
The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases. Questions or suggestions for topics should be addressed to Dominic A. Solimando, Jr, President, Oncology Pharmacy Services, Inc., 4201 Wilson Blvd #110-545, Arlington, VA 22203, e-mail: OncRxSvc@comcast...
November 2015: Hospital Pharmacy
https://www.readbyqxmd.com/read/27698500/arsenic-trioxide-and-tretinoin-aso-atra-for-acute-promyelocytic-leukemia-apl
#11
Erin Damery, Dominic A Solimando, J Aubrey Waddell
The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases. Questions or suggestions for topics should be addressed to Dominic A. Solimando, Jr., President, Oncology Pharmacy Services, Inc., 4201 Wilson Blvd #110-545, Arlington, VA 22203, e-mail: OncRxSvc@comcast...
September 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27682600/impact-of-pharmacist-interventions-on-cost-avoidance-in-an-ambulatory-cancer-center
#12
Laura A Randolph, Cheri K Walker, Ann T Nguyen, Subi R Zachariah
OBJECTIVE: To provide a foundation to justify the presence of a full-time clinical pharmacist in the ambulatory cancer center in addition to an existing centralized pharmacist through cost avoidance calculation and patient and staff satisfaction surveys. METHODS: The prospective, pilot study took place in an ambulatory cancer center over four weeks in 2014. Cost avoidance values were assigned to interventions performed by a pharmacy resident, who was present in the ambulatory cancer center during clinic hours, along with a centralized oncology pharmacist routinely working with the cancer center...
September 27, 2016: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/27663562/expanding-care-through-a-layered-learning-practice-model
#13
Jill S Bates, Larry W Buie, Lindsey B Amerine, Scott W Savage, Stephen F Eckel, Rachana Patel, John M Valgus, Kamakshi Rao, Rowell Daniels
PURPOSE: The outcomes of a patient-centered layered learning practice model (LLPM) in which the clinical specialist acted as the attending pharmacist and managed a pharmacy team to provide direct patient care were evaluated. METHODS: Two 30-day evaluations were conducted on the acute care malignant hematology and medical oncology services of the University of North Carolina Medical Center in 2011. The primary objective of this study was to design an LLPM that used a team to expand the pharmacist care services offered...
September 23, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27623830/-use-of-personal-protective-equipment-under-occupational-exposure-to-cytostatics
#14
Sylwia Krzemińska, Małgorzata Pośniak, Małgorzata Szewczyńska
BACKGROUND: A growing number of cancer cases enhances the usage of cytostatic agents and thereby contributes to the increase in the number of health care workers occupationally exposed to cytostatics. MATERIAL AND METHODS: This article presents the results of the survey aimed at obtaining data on the reduction of occupational exposure through using personal protective equipment by the medical and pharmaceutical personnel involved in handling cytostatics. The questionnaires were sent by mail or e-mail to oncology hospitals and pharmacies preparing cytostatic drugs...
2016: Medycyna Pracy
https://www.readbyqxmd.com/read/27621503/clofarabine-and-cytarabine-regimen-for-acute-myeloid-leukemia
#15
EDITORIAL
Kristin V Ho, Dominic A Solimando, J Aubrey Waddell
The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases. Questions or suggestions for topics should be addressed to Dominic A. Solimando, Jr, President, Oncology Pharmacy Services, Inc., 4201 Wilson Blvd #110-545, Arlington, VA 22203, e-mail: OncRxSvc@comcast...
November 2015: Hospital Pharmacy
https://www.readbyqxmd.com/read/27581596/risk-management-of-onco-hematological-drugs-how-and-how-fast-can-we-improve
#16
Mattia Altini, Marna Bernabini, Paolo Marchetti, Laura Orlando, Barbara Rebesco, Valeria Sirna
PURPOSE: Medication errors in oncology may cause severe damage to patients, professionals, and the environment. The Italian Ministry of Health issued Raccomandazione 14 to provide guidelines for prevention of errors while using antineoplastic drugs. This work aimed at analyzing Raccomandazione 14 through the different viewpoints of the hospital pharmacist, the nurse, the oncologist, and the hospital director. METHODS: Twenty-seven Italian healthcare organizations participated in a self-assessment survey evaluating compliance with Raccomandazione 14 within the oncology, hematology, and pharmacy departments...
August 29, 2016: Tumori
https://www.readbyqxmd.com/read/27559185/alectinib-ceritinib-elotuzumab-and-venetoclax
#17
J Aubrey Waddell, Dominic A Solimando
The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases. Questions or suggestions for topics should be addressed to Dominic A. Solimando, Jr, President, Oncology Pharmacy Services, Inc., 4201 Wilson Blvd #110-545, Arlington, VA 22203, e-mail: OncRxSvc@comcast...
July 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27552009/-khorama-score-as-a-predictive-tool-for-thromboembolic-events-in-high-risk-patients
#18
Verónica Kramer, Macarena Klein, Fernando Cevallos, Marcela Cárcamo
BACKGROUND: There is an established relation between cancer and the development of thromboembolic venous disease. Khorana et al developed a predictive score using clinical characteristics and laboratory values to stratify patients according to their risk. AIM: To characterize using Khorana score, patients with active cancer and a diagnosis of thromboembolic disease during hospitalization in an oncology hospital. MATERIAL AND METHODS: Review of records of the pharmacy of the hospital, selecting patients who received heparin in therapeutic doses during their hospitalization...
May 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27540253/optimisation-of-pharmacy-content-in-paediatric-oncology-and-haematology-clinical-trial-protocols-experience-of-chemotherapy-pharmacy-advisory-service-cpas-from-2011-to-present
#19
Rachel Greer, Sally Harvey
AIM: Clarity and accuracy of the pharmacy aspects of cancer clinical trial protocols is essential. Inconsistencies and ambiguities in protocols have the potential to delay research and jeopardise both patient safety and the collection of credible data. The Chemotherapy and Pharmacy Advisory Service (CPAS) was established in 2007 by the UK National Cancer Research Network, currently known as National Institute for Health Research Clinical Research Network, to improve the quality of pharmacy-related content in cancer clinical trial protocols...
September 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27540218/rates-and-types-of-prescribing-errors-and-related-interventions-in-paediatric-oncology
#20
Claire Fosbrook
AIM: The aim of the pharmacy intervention audit was to prospectively record the number and type of interventions made to paediatric oncology chemotherapy prescriptions. This baseline data will be used in the future to assess the impact of electronic prescribing (EP) on prescribing error or intervention rates.Independently from the EP project research, I interrogated the data to establish if there was a correlation between prescribing workload and rate of errors or interventions. I predicted that an 'overworked' prescriber would make more mistakes due to the volume of the workload and a less frequent prescriber would make more mistakes due to scarce use of these skills...
September 2016: Archives of Disease in Childhood
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