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Polypoid gallbladder

Tanyaporn Chantarojanasiri, Yoshiki Hirooka, Hiroki Kawashima, Eizaburo Ohno, Pradermchai Kongkam, Hidemi Goto
Endoscopic ultrasound (EUS) has recently played an increasing role in the diagnosis of gallbladder diseases. This review aims to summarize the role of EUS in the diagnosis of gallbladder lesions. EUS provides high-resolution images that can improve the diagnosis of gallbladder polypoid lesions and microlithiasis, in addition to evaluating gallbladder thickness and staging of gallbladder carcinoma. Contrast-enhancing agents may be useful for the differential diagnosis of gallbladder lesions, but the evidence of their effectiveness is still limited and further studies are required in this area to establish its usefulness...
September 12, 2016: Journal of Medical Ultrasonics
Yoo Shin Choi, Jae Hyuk Do, Suk Won Seo, Seung Eun Lee, Hyoung Chul Oh, Yun Joo Min, Hyun Kang
PURPOSE: To determine the prevalence of and investigate the risk factors for gallbladder (GB) polypoid lesions in a healthy population. MATERIALS AND METHODS: A total of 23827 subjects who underwent abdominal ultrasonography in conjunction with health screening examinations were retrospectively analyzed. The prevalence of risk factors for GB polypoid lesions were evaluated. In addition, risk factors according to the number of polypoid lesions and the presence of stones with polypoid lesions were investigated...
November 2016: Yonsei Medical Journal
Mohamed Elmasry, Don Lindop, Declan F J Dunne, Hassan Malik, Graeme J Poston, Stephen W Fenwick
INTRODUCTION: Gallbladder polyps (GBPs) are a common incidental finding on ultrasound (US) examination. The malignant potential of GBPs is debated, and there is limited guidance on surveillance. This systematic review sought to assess the natural history of ultrasonographically diagnosed GBPs and their malignant potential. METHODS: The keywords: "Gallbladder" AND ("polyp" OR "polypoid lesion") were used to conduct a search in four reference libraries to identify studies which examined the natural history of GBPs diagnosed by US...
September 2016: International Journal of Surgery
Masamichi Matsuda, Goro Watanabe, Masaji Hashimoto, Harushi Utagawa, Kazuo Takeuchi
The patient, a 50-year-old man, had been followed up by a neurologist under the diagnosis of mitochondrial encephalomyopathy. A gallstone detected by abdominal ultrasonography (US) had been present for several years, but localized protrusions of the gallbladder wall were first seen at the fundus in May 1995. Endoscopic US after abdominal US showed several small protruding lesions with maximum diameters of about 7 mm. These lesions had irregular surfaces and low internal echogenicity. An external high echoic layer, which represented the subserosa of the gallbladder, was intact...
March 2002: Journal of Medical Ultrasonics
Kee-Taek Jang, Sangjeong Ahn
CONTEXT: -The identification of a precursor lesion is important to understanding the histopathologic and genetic alterations in carcinogenesis. There are a plethora of terminologies that describe precursor lesions of the pancreatobiliary tract, ampulla of Vater, and gallbladder. The current terminologies for precursor lesions may make it difficult to understand the tumor biology. Here, we propose the concept of tumoral and flat intraepithelial neoplasia to improve our understanding of precursor lesions of many epithelial organs, including the pancreatobiliary tract, ampulla of Vater, and gallbladder...
May 2016: Archives of Pathology & Laboratory Medicine
Guang Yang, Haixia Qin, Anwar Raza, George W Saukel, Naveenraj Solomon, Marcos Michelotti, Ravi Raghavan
Adenomas of the gallbladder are uncommon benign epithelial neoplasms. Rarely, they can give rise to gallbladder cancer, which is the most common malignancy of the biliary tract, carrying a poor prognosis and decreased survival. Here we report the case histories of two patients, 40-year-old and 53-year-old males who presented with >1 cm gallbladder polyps, which were detected and confirmed using various imaging studies. Cholecystectomy was performed on both patients and the subsequent pathologic exam revealed 1...
April 2016: Journal of Gastrointestinal Oncology
Di Zhou, Jian-Dong Wang, Yong Yang, Wen-Long Yu, Yong-Jie Zhang, Zhi-Wei Quan
BACKGROUND: Early diagnosis of gallbladder cancer (GBC) can remarkably improve the prognosis of patients. This study aimed to develop a nomogram for individualized diagnosis of stage I-II GBC in chronic cholecystitis patients with gallbladder wall thickening. METHODS: The nomogram was developed using logistic regression analyses based on a retrospective cohort consisting of 89 consecutive patients with stage I-II GBC and 1240 patients with gallbladder wall thickening treated at one biliary surgery center in Shanghai between January 2009 and December 2011...
April 2016: Hepatobiliary & Pancreatic Diseases International: HBPD INT
Mafalda Costa Neves, Kyriakos Neofytou, Alexandros Giakoustidis, Stephen Hazell, Andrew Wotherspoon, Martin Gore, Satvinder Mudan
BACKGROUND: Renal cell carcinoma accounts for 90% of renal neoplasms and metastatic disease is common. One third of newly diagnosed cases will have synchronous metastases at diagnosis and further 25-50 % will develop metachronous disease. CASE PRESENTATION: This study presents two new cases of gallbladder metastasis from renal cell carcinoma (RCC) from our institution and reviews the published literature. The final cohort included 52 evaluable patients. M/F ratio was 2:1 and median age was 62...
2016: World Journal of Surgical Oncology
Kah Poh Loh, Deborah Nautsch, James Mueller, David Desilets, Vaibhav Mehendiratta
Biliary adenomas that are usually found in surgically removed gallbladders are rare, but can also occur in the extrahepatic biliary tree. We present a case series of extrahepatic bile duct adenomas at our institution, along with a review of the literature. All three patients with extrahepatic biliary adenomas (two in the common bile ducts, one in the hepatic duct) were female with a mean age of 74 years. On initial presentation, none of the patients had obstructive jaundice but two of the three patients had symptoms of biliary origin...
February 2016: Endoscopy International Open
Nikita R Bhatt, Amy Gillis, Craig O Smoothey, Faisal N Awan, Paul F Ridgway
BACKGROUND: There are no evidence-based guidelines to dictate when Gallbladder Polyps (GBPs) of varying sizes should be resected. AIM: To identify factors that accurately predict malignant disease in GBP; to provide an evidence-based algorithm for management. METHODS: A systematic review following PRISMA guidelines was performed using terms "gallbladder polyps" AND "polypoid lesion of gallbladder", from January 1993 and September 2013. Inclusion criteria required histopathological report or follow-up of 2 years...
October 2016: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
Yijiang Hu, Di Jia, Zhengdao Xu, Jiao Wang, Huifang Cai, Wei Yang, Zhaoping Wang, Tonghua Zhang, Yujie Li, Jianxin Chen
OBJECTIVE: To evaluate the efficiency of diffusion-weighted MRI in differentiating between benign and malignant polypoid gallbladder lesions. METHODS: The study population consisted of 10 benign (5 polyps, 3 adenomyomatosis and 2 adenomas) and 13 malignant (all adenocarcinomas) polypoid gallbladder lesions treated in hospital from November 2007 to May 2014. DWI was evaluated by two observers. Qualitatively, the signal intensity of the lesions on DWI was visually evaluated and categorized as iso, high, or very high signal...
October 20, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Byung Hyo Cha
BACKGROUND: Gallbladder cancer (GBC) is a rare but highly invasive malignancy characterized by poor survival. In a national cancer survey, the age-standardized incidence rate of GBC was highest in Jeju Island among the 15 provinces in South Korea. The aim of this descriptive epidemiological study was to suggest the modifiable risk factors for this rare malignant disease in Jeju Island by performing an age-sex-matched case- control study. MATERIALS AND METHODS: The case group included patients diagnosed with GBC at the Department of Internal Medicine of Cheju Halla General Hospital, Jeju, South Korea, within the 5-year study period...
2015: Asian Pacific Journal of Cancer Prevention: APJCP
So Won Lee, Seung Yon Baek, Sun Hee Sung
We report herein a rare case of incidentally detected combined undifferentiated and neuroendocrine carcinomas of the gallbladder. An incidental gallbladder malignancy was revealed on abdominal ultrasound and multi-detector computed tomography in a 54-year-old man. A short distance from the main polypoid hypoechoic mass at the fundus of the gallbladder, focal wall thickening was noted with prominently increased power Doppler flow. Extended cholecystectomy was performed, and histology confirmed the main polypoid mass as undifferentiated carcinoma and the separate nodule as neuroendocrine carcinoma...
May 2015: Journal of Radiology Case Reports
Jingjing Guo, Gang Wu, Zhongwen Zhou
BACKGROUND: The preoperative diagnosis of gallbladder polypoid lesions is difficult, justifying the lack of consensus on the appropriate treatment. OBJECTIVE: The aim of this study was to identify the characteristics of each type of polypoid lesion of the gallbladder and the indications for surgery. METHODS: Between January 1999 and December 2012, clinical data were retrospectively correlated with the histopathologic characteristics of polypoid lesions in 160 patients who underwent cholecystectomy...
2015: International Journal of Clinical and Experimental Pathology
S W Kim, H C Kim, D M Yang, J K Ryu, K Y Won
Gallbladder carcinomas can present with varied imaging features on computed tomography. The three major imaging features include (1) focal or diffuse wall thickening with or without irregularity of the gallbladder; (2) polypoidal intraluminal mass; and (3) large mass obscuring and replacing the gallbladder, often extending to the liver. Patterns of wall thickening or polypoid growth are often confused with various benign gallbladder diseases due to overlap of imaging findings. Moreover, gallbladder carcinomas that coexist with benign gallbladder diseases make accurate preoperative diagnosis more difficult...
January 2016: Clinical Radiology
Barbara Seeliger, Cosimo Callari, Michele Diana, Didier Mutter, Jacques Marescaux
Introduction. The only curative therapeutic approach for renal cell carcinoma (RCC) is surgery. Laparoscopic surgery for RCC has become an established surgical procedure with equivalent cancer-free survival rate, following the same surgical oncological principles as open surgery. Metastatic RCC of the gallbladder is a rare phenomenon. Hence, there are few reports regarding their management. Case Presentation. We report 2 cases of gallbladder metastasis from clear cell RCC treated by laparoscopic cholecystectomy...
July 2013: Journal of Investigative Medicine High Impact Case Reports
David Kasle, Amir A Rahnemai-Azar, Shahida Bibi, Vinaya Gaduputi, Brian F Gilchrist, Daniel T Farkas
Detection of polypoid lesions of the gallbladder is increasing in conjunction with better imaging modalities. Accepted management of these lesions depends on their size and symptomatology. Polyps that are symptomatic and/or greater than 10 mm are generally removed, while smaller, asymptomatic polyps simply monitored. Here, a case of carcinoma-in-situ is presented in a 7 mm gallbladder polyp. A 25-year-old woman, who had undergone a routine cholecystectomy, was found to have an incidental 7 mm polyp containing carcinoma in situ...
July 25, 2015: World Journal of Gastrointestinal Endoscopy
Masaru Koizumi, Naohiro Sata, Naoya Kasahara, Kazue Morishima, Yuji Kaneda, Takehito Fujiwara, Makoto Ota, Masanobu Hyodo, Yoshikazu Yasuda
We report two cases of carcinoid tumor of the gallbladder. Case 1 was a 59-year-old woman who presented with epigastric pain. Abdominal ultrasonography and computed tomography (CT) revealed a 16 mm polypoid lesion in the neck of the gallbladder. Tumor markers were within normal limits. Open cholecystectomy was performed with a preoperative diagnosis of early cancer of the gallbladder. Case 2 was a 45-year-old man. A polyp in the gallbladder was incidentally detected on annual checkup. Ultrasound and CT showed an 18 mm protruding lesion in the neck of the gallbladder...
October 2011: Clinical Journal of Gastroenterology
Nobuyuki Ozaki, Daisuke Hashimoto, Yoshiaki Ikuta, Akira Chikamoto, Hiroshi Takamori, Hideo Baba
Duplicated gallbladders are rare congenital anomalies that are important in clinical practice as they may cause clinical, surgical, and diagnostic problems. Here, we describe the case of a 79-year-old female patient who presented with acute cholangitis. Abdominal ultrasonography, endoscopic ultrasonography, computed tomography, and magnetic resonance imaging revealed an intrahepatic cystic lesion, suggesting communication with the intrahepatic bile duct; no evidence of a polypoid lesion within the cystic lesion was observed...
August 2014: Clinical Journal of Gastroenterology
Vincent M Mellnick, Christine O Menias, Kumar Sandrasegaran, Amy K Hara, Ania Z Kielar, Elizabeth M Brunt, Maria B Majella Doyle, Nirvikar Dahiya, Khaled M Elsayes
No abstract text is available yet for this article.
July 2015: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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