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Polypoid gallbladder

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https://www.readbyqxmd.com/read/28216138/clinicopathologic-characteristics-of-young-patients-with-gallbladder-cancer
#1
Sung-Im Do, Hyoun Wook Lee, Jin Hee Sohn, Kyungeun Kim
Gallbladder cancer is the most common biliary tract cancer and the fifth most common cancer of the digestive system. However, the clinicopathologic features of gallbladder cancer in young Korean patients have not been studied. This study included 101 consecutive cases of gallbladder cancer that underwent cholecystectomy at Kangbuk Samsung Hospital from December 1990 to March 2011. The patients were divided into two groups by age at initial diagnosis of gallbladder cancer: a young patient group aged less than 45 years and an old patient group aged 45 or older...
December 29, 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28133072/-clinicopathological-study-of-incidental-gallbladder-cancer-diagnosed-after-laparoscopic-cholecystectomy
#2
Yoshito Tomimaru, Kozo Noguchi, Hirotsugu Nagase, Atsushi Hamabe, Masashi Hirota, Kazuteru Oshima, Tsukasa Tanida, Tomono Kawase, Shunji Morita, Hiroshi Imamura, Takashi Iwazawa, Kenzo Akagi, Keizo Dono
The aim of this study was to clarify the clinicopathological characteristics of incidental gallbladder cancer(iGBC)diagnosed after laparoscopic cholecystectomy. A total of 33 patients diagnosed with iGBC were enrolled in this study, and their clinicopathological characteristics were investigated. Preoperative diagnoses were as follows: cholelithiasis in 16 patients, polypoid lesions in 8, cholecystitis in 7, and adenomyomatosis in 2. Depth of mural invasion of iGBC was M in 14 cases, MP in 3, SS in 12, and deeper than SS in 4...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28044300/a-mimicker-of-gallbladder-carcinoma-cystic-gastric-heterotopia-with-intestinal-metaplasia
#3
Gonca Özgün, Şaduman Balaban Adim, Nesrin Uğraş, Sadık Kiliçturgay
Heterotopic gastric mucosa in the gallbladder is an unusual entity and is usually clinically silent. We report a 75-year-old female patient who presented with intermittent upper abdomial pain radiating to the back. Abdominal imaging studies showed a sessile polypoid lesion and a gallstone in the gallbladder. Gallbladder carcinoma was suspected and cholecystectomy performed. Intraoperative frozen section examination suggested mucinous tumor, suspicious for malignancy. However, the permanent sections revealed aberrant gastric tissue consisted of gastric pyloric and fundic glands of heterotopic gastric mucosa with intestinal metaplasia in the gallbladder...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28039652/polypoid-lesions-of-the-gallbladder-analysis-of-1204-patients-with-long-term-follow-up
#4
Shu-Cheng Chou, Shih-Chin Chen, Yi-Ming Shyr, Shin-E Wang
BACKGROUND: Polypoid lesions of the gallbladder (PLG) are common, and most are benign. Few lesions are found to be malignant, but are not preoperatively distinguished as such using common imaging modalities. Therefore, we compared characteristics of benign and malignant PLGs in depth. METHODS: We enrolled 1204 consecutive patients diagnosed with PLG at Taipei Veterans General Hospital between January 2004 and December 2013. Patients underwent either surgery or regular follow-up with various imaging modalities for at least 24 months...
December 30, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27994338/chylous-ascites-in-advanced-gallbladder-cancer
#5
Mallika Tewari, Rupesh Singh, H S Shukla
Chylous ascites is a very rare occurrence in a patient with gallbladder cancer (GBC), and only six cases have been reported. We report here one such case in a 55-year-old lady who presented to us with upper abdominal pain for 6 months. A polypoidal gallbladder mass with minimal liver invasion but with multiple subcentimeter pericholedochal, common hepatic, mesenteric, and para-aortic lymph nodes was found on contrast-enhanced computed tomography scan. At laparotomy, the abdomen had milky fluid with engorged beaded lymphatics all over the small intestine...
October 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/27832311/diagnostic-accuracy-of-transabdominal-high-resolution-us-for-staging-gallbladder-cancer-and-differential-diagnosis-of-neoplastic-polyps-compared-with-eus
#6
Jeong Sub Lee, Jung Hoon Kim, Yong Jae Kim, Ji Kon Ryu, Yong-Tae Kim, Jae Young Lee, Joon Koo Han
PURPOSE: To compare the diagnostic accuracy of transabdominal high-resolution ultrasound (HRUS) for staging gallbladder cancer and differential diagnosis of neoplastic polyps compared with endoscopic ultrasound (EUS) and pathology. MATERIALS AND METHODS: Among 125 patients who underwent both HRUS and EUS, we included 29 pathologically proven cancers (T1 = 7, T2 = 19, T3 = 3) including 15 polypoid cancers and 50 surgically proven polyps (neoplastic = 30, non-neoplastic = 20)...
November 10, 2016: European Radiology
https://www.readbyqxmd.com/read/27830040/incidental-non-benign-gallbladder-histopathology-after-cholecystectomy-in-an-united-kingdom-population-need-for-routine-histological-analysis
#7
Krashna Patel, Khaled Dajani, Satheesh Iype, Nikolaos A Chatzizacharias, Saranya Vickramarajah, Prateush Singh, Susan Davies, Rebecca Brais, Siong S Liau, Simon Harper, Asif Jah, Raaj K Praseedom, Emmanuel L Huguet
AIM: To analyse the range of histopathology detected in the largest published United Kingdom series of cholecystectomy specimens and to evaluate the rational for selective histopathological analysis. METHODS: Incidental gallbladder malignancy is rare in the United Kingdom with recent literature supporting selective histological assessment of gallbladders after routine cholecystectomy. All cholecystectomy gallbladder specimens examined by the histopathology department at our hospital during a five year period between March 2008 and March 2013 were retrospectively analysed...
October 27, 2016: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27619811/the-role-of-endoscopic-ultrasound-in-the-diagnosis-of-gallbladder-diseases
#8
REVIEW
Tanyaporn Chantarojanasiri, Yoshiki Hirooka, Hiroki Kawashima, Eizaburo Ohno, Pradermchai Kongkam, Hidemi Goto
Endoscopic ultrasound (EUS) has recently played an increasing role in the diagnosis of gallbladder diseases. This review aims to summarize the role of EUS in the diagnosis of gallbladder lesions. EUS provides high-resolution images that can improve the diagnosis of gallbladder polypoid lesions and microlithiasis, in addition to evaluating gallbladder thickness and staging of gallbladder carcinoma. Contrast-enhancing agents may be useful for the differential diagnosis of gallbladder lesions, but the evidence of their effectiveness is still limited and further studies are required in this area to establish its usefulness...
January 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27593864/prevalence-and-risk-factors-of-gallbladder-polypoid-lesions-in-a-healthy-population
#9
Yoo Shin Choi, Jae Hyuk Do, Suk Won Seo, Seung Eun Lee, Hyoung Chul Oh, Yun Joo Min, Hyun Kang
PURPOSE: To determine the prevalence of and investigate the risk factors for gallbladder (GB) polypoid lesions in a healthy population. MATERIALS AND METHODS: A total of 23827 subjects who underwent abdominal ultrasonography in conjunction with health screening examinations were retrospectively analyzed. The prevalence of risk factors for GB polypoid lesions were evaluated. In addition, risk factors according to the number of polypoid lesions and the presence of stones with polypoid lesions were investigated...
November 2016: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27465099/the-risk-of-malignancy-in-ultrasound-detected-gallbladder-polyps-a-systematic-review
#10
REVIEW
Mohamed Elmasry, Don Lindop, Declan F J Dunne, Hassan Malik, Graeme J Poston, Stephen W Fenwick
INTRODUCTION: Gallbladder polyps (GBPs) are a common incidental finding on ultrasound (US) examination. The malignant potential of GBPs is debated, and there is limited guidance on surveillance. This systematic review sought to assess the natural history of ultrasonographically diagnosed GBPs and their malignant potential. METHODS: The keywords: "Gallbladder" AND ("polyp" OR "polypoid lesion") were used to conduct a search in four reference libraries to identify studies which examined the natural history of GBPs diagnosed by US...
September 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27277593/ultrasonographic-features-of-polypoid-myoglandular-hyperplasia-of-the-gallbladder-that-were-difficult-to-distinguish-from-early-gallbladder-cancer
#11
Masamichi Matsuda, Goro Watanabe, Masaji Hashimoto, Harushi Utagawa, Kazuo Takeuchi
The patient, a 50-year-old man, had been followed up by a neurologist under the diagnosis of mitochondrial encephalomyopathy. A gallstone detected by abdominal ultrasonography (US) had been present for several years, but localized protrusions of the gallbladder wall were first seen at the fundus in May 1995. Endoscopic US after abdominal US showed several small protruding lesions with maximum diameters of about 7 mm. These lesions had irregular surfaces and low internal echogenicity. An external high echoic layer, which represented the subserosa of the gallbladder, was intact...
March 2002: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27128300/tumoral-versus-flat-intraepithelial-neoplasia-of-pancreatobiliary-tract-gallbladder-and-ampulla-of-vater
#12
REVIEW
Kee-Taek Jang, Sangjeong Ahn
CONTEXT: -The identification of a precursor lesion is important to understanding the histopathologic and genetic alterations in carcinogenesis. There are a plethora of terminologies that describe precursor lesions of the pancreatobiliary tract, ampulla of Vater, and gallbladder. The current terminologies for precursor lesions may make it difficult to understand the tumor biology. Here, we propose the concept of tumoral and flat intraepithelial neoplasia to improve our understanding of precursor lesions of many epithelial organs, including the pancreatobiliary tract, ampulla of Vater, and gallbladder...
May 2016: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27034818/pyloric-gland-adenoma-of-gallbladder-reports-of-two-cases-and-a-brief-review-of-literature
#13
Guang Yang, Haixia Qin, Anwar Raza, George W Saukel, Naveenraj Solomon, Marcos Michelotti, Ravi Raghavan
Adenomas of the gallbladder are uncommon benign epithelial neoplasms. Rarely, they can give rise to gallbladder cancer, which is the most common malignancy of the biliary tract, carrying a poor prognosis and decreased survival. Here we report the case histories of two patients, 40-year-old and 53-year-old males who presented with >1 cm gallbladder polyps, which were detected and confirmed using various imaging studies. Cholecystectomy was performed on both patients and the subsequent pathologic exam revealed 1...
April 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/27020635/individualized-nomogram-improves-diagnostic-accuracy-of-stage-i-ii-gallbladder-cancer-in-chronic-cholecystitis-patients-with-gallbladder-wall-thickening
#14
COMPARATIVE STUDY
Di Zhou, Jian-Dong Wang, Yong Yang, Wen-Long Yu, Yong-Jie Zhang, Zhi-Wei Quan
BACKGROUND: Early diagnosis of gallbladder cancer (GBC) can remarkably improve the prognosis of patients. This study aimed to develop a nomogram for individualized diagnosis of stage I-II GBC in chronic cholecystitis patients with gallbladder wall thickening. METHODS: The nomogram was developed using logistic regression analyses based on a retrospective cohort consisting of 89 consecutive patients with stage I-II GBC and 1240 patients with gallbladder wall thickening treated at one biliary surgery center in Shanghai between January 2009 and December 2011...
April 2016: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/27005674/two-cases-of-gallbladder-metastasis-from-renal-cell-carcinoma-and-review-of-literature
#15
Mafalda Costa Neves, Kyriakos Neofytou, Alexandros Giakoustidis, Stephen Hazell, Andrew Wotherspoon, Martin Gore, Satvinder Mudan
BACKGROUND: Renal cell carcinoma accounts for 90% of renal neoplasms and metastatic disease is common. One third of newly diagnosed cases will have synchronous metastases at diagnosis and further 25-50 % will develop metachronous disease. CASE PRESENTATION: This study presents two new cases of gallbladder metastasis from renal cell carcinoma (RCC) from our institution and reviews the published literature. The final cohort included 52 evaluable patients. M/F ratio was 2:1 and median age was 62...
March 22, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/26878036/adenomas-involving-the-extrahepatic-biliary-tree-are-rare-but-have-an-aggressive-clinical-course
#16
Kah Poh Loh, Deborah Nautsch, James Mueller, David Desilets, Vaibhav Mehendiratta
Biliary adenomas that are usually found in surgically removed gallbladders are rare, but can also occur in the extrahepatic biliary tree. We present a case series of extrahepatic bile duct adenomas at our institution, along with a review of the literature. All three patients with extrahepatic biliary adenomas (two in the common bile ducts, one in the hepatic duct) were female with a mean age of 74 years. On initial presentation, none of the patients had obstructive jaundice but two of the three patients had symptoms of biliary origin...
February 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/26825588/evidence-based-management-of-polyps-of-the-gall-bladder-a-systematic-review-of-the-risk-factors-of-malignancy
#17
REVIEW
Nikita R Bhatt, Amy Gillis, Craig O Smoothey, Faisal N Awan, Paul F Ridgway
BACKGROUND: There are no evidence-based guidelines to dictate when Gallbladder Polyps (GBPs) of varying sizes should be resected. AIM: To identify factors that accurately predict malignant disease in GBP; to provide an evidence-based algorithm for management. METHODS: A systematic review following PRISMA guidelines was performed using terms "gallbladder polyps" AND "polypoid lesion of gallbladder", from January 1993 and September 2013. Inclusion criteria required histopathological report or follow-up of 2 years...
October 2016: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/26814118/-value-of-diffusion-weighted-mri-in-differentiation-between-benign-and-malignant-polypoid-gallbladder-lesions
#18
Yijiang Hu, Di Jia, Zhengdao Xu, Jiao Wang, Huifang Cai, Wei Yang, Zhaoping Wang, Tonghua Zhang, Yujie Li, Jianxin Chen
OBJECTIVE: To evaluate the efficiency of diffusion-weighted MRI in differentiating between benign and malignant polypoid gallbladder lesions. METHODS: The study population consisted of 10 benign (5 polyps, 3 adenomyomatosis and 2 adenomas) and 13 malignant (all adenocarcinomas) polypoid gallbladder lesions treated in hospital from November 2007 to May 2014. DWI was evaluated by two observers. Qualitatively, the signal intensity of the lesions on DWI was visually evaluated and categorized as iso, high, or very high signal...
October 20, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/26745100/epidemiological-characteristics-of-gallbladder-cancer-in-jeju-island-a-single-center-clinically-based-age-sex-matched-case-control-study
#19
COMPARATIVE STUDY
Byung Hyo Cha
BACKGROUND: Gallbladder cancer (GBC) is a rare but highly invasive malignancy characterized by poor survival. In a national cancer survey, the age-standardized incidence rate of GBC was highest in Jeju Island among the 15 provinces in South Korea. The aim of this descriptive epidemiological study was to suggest the modifiable risk factors for this rare malignant disease in Jeju Island by performing an age-sex-matched case- control study. MATERIALS AND METHODS: The case group included patients diagnosed with GBC at the Department of Internal Medicine of Cheju Halla General Hospital, Jeju, South Korea, within the 5-year study period...
2015: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/26622929/combined-undifferentiated-and-neuroendocrine-carcinomas-of-the-gallbladder-appearing-as-two-separate-lesions-a-case-report-with-radiological-pathological-correlation
#20
So Won Lee, Seung Yon Baek, Sun Hee Sung
We report herein a rare case of incidentally detected combined undifferentiated and neuroendocrine carcinomas of the gallbladder. An incidental gallbladder malignancy was revealed on abdominal ultrasound and multi-detector computed tomography in a 54-year-old man. A short distance from the main polypoid hypoechoic mass at the fundus of the gallbladder, focal wall thickening was noted with prominently increased power Doppler flow. Extended cholecystectomy was performed, and histology confirmed the main polypoid mass as undifferentiated carcinoma and the separate nodule as neuroendocrine carcinoma...
May 2015: Journal of Radiology Case Reports
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