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Athanasios Rinotas
At the beginning of the twentieth century, historians associated the alchemy of the third-century alchemist Zosimus of Panopolis with Platonism and Aristotelianism, explicating his theory of alchemical transmutation under the intellectual umbrella of these philosophical traditions. More recently, scholars of alchemy such as Christina Viano and William Newman have suggested a connection between Zosimean alchemy and Stoicism. Through a close reading of texts in Zosimus's corpus, this paper posits a Stoic interpretation of several aspects of Zosimean alchemy, focusing on the concepts of pneuma and tension...
August 2017: Ambix
Marco Beretta
Glassmaking has prospered as an art since the late Middle Ages. It is therefore surprising that the first systematic treatise exclusively devoted to it appeared as late as 1612. In this article I explore the experimental background of Antonio Neri's L'Arte Vetraria, and its intimate connection with an ancient alchemical tradition and with more contemporary efforts to introduce technical innovations. Furthermore, the active role played by Antonio Neri, a clergyman and alchemist in the service of Antonio de' Medici, sheds new light on the patronage of the Medici court...
2017: Technology and Culture
Nirmal Veeramachaneni, Dennis Wigle, Judy C Boughey
No abstract text is available yet for this article.
March 2017: Bulletin of the American College of Surgeons
Peter J Forshaw
This essay examines the elaborate title pages of some of alchemist, astrologer, and bibliophile John Dee's publications with a focus on the two best known works that feature his famous Hieroglyphic Monad, the Propaedeumata Aphoristica (1558) and Monas Hieroglyphica (1564). The aim is to cast light on its context, identify sources for some textual influences in the works, unpack the visual symbolism in the two "monadic" title pages in relation to the two complementary sciences of "superior" and "inferior" astronomy, speculate on some of the more enigmatic details, and conclude with a brief discussion of a possible astrological significance to the dates of composition of the Monas Hieroglyphica...
August 21, 2017: Ambix
Stephen Clucas
John Dee's Monas Hieroglyphica (1564) was a work which involved a close collaboration between its author and his "singular friend" the Antwerp printer Willem Silvius, in whose house Dee was living whilst he composed the work and saw it through the press. This article considers the reasons why Dee chose to collaborate with Silvius, and the importance of the intellectual culture - and the print trade - of the Low Countries to the development of Dee's outlook. Dee's Monas was probably the first alchemical work which focused exclusively on the diagrammatic representation of the alchemical process, combining diagrams, cosmological schemes, and various forms of tabular grid...
August 10, 2017: Ambix
M A Riva, F Cesana, F Achilli, F Scordo, G Cesana
BACKGROUND: Patients with chronic heart failure may suffer from severe thirst, even if mechanisms that cause thirst in subjects affected by this condition are not clear. Medical and non-medical authors may have already recognized this symptom during the classical age. METHODS: We analyzed association between thirst and dropsy (an ancient medical term used to indicate different conditions including chronic heart failure) in past medical and non-medical literature...
August 3, 2017: International Journal of Cardiology
Steven Vanden Broecke
It is well known that John Dee presented the Monas Hieroglyphica (1564) as the basis for a wholesale transformation of early modern knowledge culture - a claim that raises obvious issues of epistemic credibility. This paper discusses the social techniques that Dee proposed as a solution to these issues. First, our reconstruction of the "socio-epistemic imaginary" that Dee conveyed in the Monas shows how the marriage between a traditional rhetoric of secrecy and a courtly politicising of natural philosophy allowed Dee to invent social distinctions between credible and false purveyors of true knowledge...
August 6, 2017: Ambix
S Brosseau, C Naltet, M Nguenang, V Gounant, P Mordant, B Milleron, Y Castier, G Zalcman
Surgery is still the main treatment in early-stage of non-small cell lung cancer with 5-year survival of stage IA patients exceeding 80%, but 5-year survival of stage II patients rapidly decreasing with tumor size, N status, and visceral pleura invasion. The major metastatic risk in such patients has supported clinical research assessing systemic or loco-regional perioperative treatments. Modern phase 3 trials clearly validated adjuvant or neo-adjuvant platinum-based chemotherapy in resected stage I-III patients as a standard treatment of which value has been reassessed several independent meta-analyses, showing a 5% benefit in 5y-survival, and a decrease of the relative risk for death around from 12 to 25%...
June 2017: Revue des Maladies Respiratoires
Stanislav Južnič
Barbara Celjska je bila gotovo najbogatejša alkimistka vseh časov. Prispevek skuša pojasniti kakšni poskusi so potekali v njenem laboratoriju in nakazati, katere tehniške kemijske naprave je utegnila pri tem uporabljati. Ker je bila večina leteh iz zlahka lomljivih snovi, bi bilo njihovo iskanje brškone brez haska, saj ni veliko upanja za njihovo ohranitev. Barbara of Cilli was certainly the richest female alchemist of all times. The article tries to explain what kind of experiments she carried out in her laboratory and indicate which technical chemical plant she likely has used...
June 2017: Acta Chimica Slovenica
José Vieira Leitão
The Benedictine monk Benito Jerónimo Feijoo (1676-1764) is now considered one of the major figures of the Spanish and Iberian Enlightenment. However his work, both in Spain and in Portugal, was far from being universally acclaimed. His critical approach to the subject of alchemy in his essay "Piedra Filosofal," published in the third volume of his magisterial Teatro Crítico Universal (1726-1739), sparked an unexpected response from the Portuguese alchemist Anselmo Castelo Branco, who sought to refute Feijoo's claims in his own work, the Ennoea...
January 30, 2017: Ambix
Stanislav Južnič
One of the most important Mid-European professor with more than six thousand academic descendants was the leading Slovenian erudite Jurij Vega. In broader sense, Vega's and other applied sciences of the south of Holy Roman Empire of German Nationality were connected with the mercury mine of Idrija during the last half of millennia. The Idrija Mine used to be one of the two top European producers of mercury, the basic substance of atomistic alchemists. Idrija Mine contributions to the history of techniques, their examinations and approbations is comparable to the other Mid-European achievements...
December 2016: Acta Chimica Slovenica
I M Donaldson
Around the year 1643, Joan Baptista van Helmont, a Flemish chemist, alchemist and physician who had devised what he claimed to be a new form of medicine, proposed a 'challenge' to traditional Galenic physicians to compare treatment of fever by traditional methods and by a regime which did not involve bloodletting and purging. Two groups of patients were to be treated and 'casting of lots' was to be used - in some way not specified in detail - to decide who received which treatment. This 'challenge' has been regarded as the first proposal for the use of randomisation in a clinical trial...
September 2016: Journal of the Royal College of Physicians of Edinburgh
Rafał T Prinke
The Polish alchemist Michael Sendivogius is best known for the influential Novum lumen chymicum, a work composed of three separate texts. Sendivogius's authorship was questioned in the mid-seventeenth century, and these reservations are still held by some modern historians. On the other hand, other early modern and modern readers not only accepted his authorship of all three texts, but also ascribed as many as eleven texts to him. This paper discusses the key works published under the anagrammatised name of Sendivogius with the aim of resolving the authorship question...
November 3, 2016: Ambix
Claus Priesner
This paper explores the relationship between three illustrated alchemical treatises, all of which are associated with Jewish adepts: the famous Le Livre des figures hieroglyphiques attributed to Nicolas Flamel, and two treatises published in 1735 in Erfurt-the Uraltes Chymisches Werckh and the Donum Dei. The Werckh is supposedly written by Rabbi Abraham Eleazar, while the Donum Dei is attributed to an ancient alchemist-cabalist, Rabbi Samuel Baruch. I argue that these authors are fictitious, and that both works were in fact written in the early eighteenth century by their supposed editor, the probably pseudonymous Julius Gervasius...
February 2016: Ambix
Nancy Rawson, Ali Quraishi, Thomas J Bruno
Since the days of the alchemist, the observation that some substances have a smell while other substances do not has been a source of fascination. The sense of smell, or olfaction, is our least understood sense, however it is important for many human functions, including digestion, food selection and hazard avoidance. The detailed explanation of why individual chemicals (called odorants) might have a particular smell is still elusive. The situation with mixtures of odorants is even more complex and interesting...
November 2011: Journal of Research of the National Institute of Standards and Technology
Biagio Ricciardi, Elisabetta Ricciardi, Carlo Alberto Ricciardi
Arnaldo de Villanova, was a Catalan Physician, born in Villanova de Grau, a suburb of Valencia - Spain about 1235. He died off the coast of Genoa in 1311 during a sea voyage departing from Messina in Sicily, during a diplomatic mission by Pope Clement V in Avignon on orders by the King of Sicily. He was a so famous and clever scientist of the thirteenth century, to give his name to the Universitary Hospital of Montpellier - France. His interests ranged from theology, to politics, medicine, and anymore alchemy...
February 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
Achsah Philip, Avani Desai, Phouc Anne Nguyen, Patrick Birney, Anthony Colavecchia, Rusol Karralli, Lindsey Smith, Dirk Lorimer, Gwen Burgess, Kyle Munch, Nelvin Daniel, Jason Lionetti, Kevin W Garey
PURPOSE: Pharmacy leader development over time was analyzed using the seven action logics. METHODS: As part of an ongoing leadership seminar series, students were required to select a visionary pharmacy leader and conduct a structured interview to evaluate pharmacy leaders' action logics. A standardized questionnaire comprising 13 questions was created by the class. Questions addressed leadership qualities during the leaders' early years, education years, and work years...
January 15, 2016: American Journal of Health-system Pharmacy: AJHP
Ramaswamy Govindan, Sumithra J Mandrekar, David E Gerber, Geoffrey R Oxnard, Suzanne E Dahlberg, Jamie Chaft, Shakun Malik, Margaret Mooney, Jeffrey S Abrams, Pasi A Jänne, David R Gandara, Suresh S Ramalingam, Everett E Vokes
The treatment of patients with metastatic non-small cell lung cancer (NSCLC) is slowly evolving from empirical cytotoxic chemotherapy to personalized treatment based on specific molecular alterations. Despite this 10-year evolution, targeted therapies have not been studied adequately in patients with resected NSCLC who have clearly defined actionable mutations. The advent of next-generation sequencing has now made it possible to characterize genomic alterations in unprecedented detail. The efforts begun by The Cancer Genome Atlas project to understand the complexities of the genomic landscape of lung cancer will be supplemented further by studying a large number of tumor specimens...
December 15, 2015: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Geoffrey R Oxnard, Colleen Watt, Dennis Wigle, Judy C Boughey
No abstract text is available yet for this article.
September 2015: Bulletin of the American College of Surgeons
Ryan S Alden, Sumithra J Mandrekar, Geoffrey R Oxnard
Genotype-directed targeted therapies have revolutionized the treatment of metastatic non-small cell lung cancer (NSCLC) but they have not yet been comprehensively studied in the adjuvant setting. Previous trials of adjuvant targeted therapy in unselected early stage NSCLC patients showed no benefit versus placebo, however retrospective data suggests improved disease free survival (DFS) with epidermal growth factor receptor (EGFR) inhibitors in patients with appropriate molecular alterations. A definitive prospective, randomized, placebo-controlled trial of targeted therapies for NSCLC is needed to determine the efficacy of targeted therapy following surgical resection and standard adjuvant therapy...
September 2015: Chinese Clinical Oncology
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