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cervical squamous intraepitelial

Zoran Protrka, Slobodan Arsenijević, Petar Arsenijević, Slobodanka Mitrović, Vesna Stanković, Miloš Milosavljević, Jasmina Nedović, Tatjana Kastratović, Janko Durić
AIM: To establish the role of co-overexpression of bcl-2 and cerbB- 2/neu protooncogenes in uterine cervix carcinogenesis, we examined 138 tissue samples of low grade cervical squamous intraepithelial lesions (SIL), high grade SIL, cervical carcinoma in situ and cervical invasive carcinoma, stage IA-IIA (study group) and 36 samples without SIL or malignancy (control group). METHODS: The expression of bcl-2 and c-erbB-2/neu was detected immunohistochemically using a monoclonal antibody...
August 2012: Medicinski Glasnik
Remzi Atilgan, Aygen Celik, Abdullah Boztosun, Erdin Ilter, Tulin Yalta, Resat Ozercan
INTRODUCTION: Cervical cancer is one of the most common female malignancy with high mortality rates in developing countries. Our purpose was to determine the prevalence of cervical cytologic abnormalities in population (strict Islamic religious area) and the detection rate of epithelial abnormalities by cervical cytology (CC). MATERIALS AND METHODS: A total of 32,026 conventional pap smear tests collected between January 2006 and January 2010 from three hospitals are retrospectively analyzed...
January 2012: Indian Journal of Pathology & Microbiology
H Robová, L Rob, M Pluta, J Kacírek, V Slavík, P Skapa, E Hamsíková, R Tachezy
OBJECTIVE: Evaluation of regression and progression of histologically confirmed low grade squamous intraepithelial lesions (LG SIL) in women under the age of 35 in context of positivity of high risk human papillomavirus (HPV HR). Evaluation of sensitivity of PAP smear and HPV HR test in women with LG SIL. DESIGN: Prospective study. SETTING: Department of Obstetrics and Gynecology, Charles University Prague, 2nd Medical Faculty, University Hospital Motol...
October 2007: Ceská Gynekologie
Maria del Refugio González-Losa, Iván Rosado-Lopez, Nina Valdez-González, Marylín Puerto-Solís
BACKGROUND: Cervical cancer is the second most common cancer of the women worldwide. Infection with some genotypes of human papillomavirus is the most important risk factor associated to cervical cancer. OBJECTIVE: To determine the prevalence and genotypes of papillomavirus in biopsies of women with squamous intraepithelial lesion and cervical cancer. STUDY DESIGN: Two hundred sequential patients of colposcopy clinic were studied. HPV diagnosis was done by polymerase chain reaction using MY09/MY11 primers, for genotyping line blot hybridization was used...
March 2004: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
H Montoya-Fuentes, A E Suárez Rincón, M P Ramírez-Muñoz, I Arévalo-Lagunas, M C Morán Moguel, M P Gallegos Arreola, S E Flores-Martínez, S Rosales Quintana, J Sánchez Corona
The purposes of this study were to estimate the infection frequency of Human Papilomavirus (HPV) and to identify the viral types in patients with diagnosis of uterine cervical cancer (UCC) and High Grade Squamous Intraepitelial lesions (HGSILs), and to correlate the molecular findings versus HPV infection suggestive clinical findings. Biopsies from 50 patients (37 HGSILs and 13 UCC) histopathologically diagnosed were studied. The presence of HPV were detected by means of the polymerase chain reaction (PCR) using consensus primers for types 6, 11, 16, 18, 31, 33, 35, and 58 among others, as well as specific primers for some of them...
April 2001: Ginecología y Obstetricia de México
J Kunz, R Rondez, C Yoshizaki, M Fivian, G Held, B Lind
Cervical smears of 554 outpatients of a hospital were examined using a blinded, split sample match pair protocol for which a conventional PAP-smear (CS) was first prepared with Cervex brush and the reminder of the sample was used for the thin-layer-preparation (TLP) according to the manual CytoRich System. The preparations of the two methods were compared with respect to quality and to sensitivity for atypias. In addition the HPV status was determined on the same cell suspension in cases with borderline changes (BLC) and dysplasias including carcinoma using the Hybrid Capture System...
October 21, 1998: Praxis
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