Zekang Ye, Qin Wang, Inam Ullah, Qingxia Lin, Tianyu Wu, Mingwen Yang, Yuansheng Fan, Zhou Dong, Tong Wang, Jianzhen Teng, Rui Hua, Yingdan Tang, Yule Li, Xiaoxuan Gong, Liang Yuan, Zhengxian Tao, Chunjian Li
It is controversial whether hemodialysis affects the efficacy of the antiplatelet agents. We aimed to investigate the impact of hemodialysis on efficacies of the antiplatelet agents in coronary artery disease (CAD) patients complicated with end-stage renal disease (ESRD). 86 CAD patients complicated with ESRD requiring hemodialysis were consecutively enrolled. After 5-day treatment with aspirin and clopidogrel or ticagrelor, the platelet aggregations induced by arachidonic acid (PLAA ) or adenosine diphosphate (PLADP ), and the P2Y12 reaction unit (PRU) were measured before and after hemodialysis...
February 23, 2024: Journal of Thrombosis and Thrombolysis