keyword
https://read.qxmd.com/read/37564831/the-kinetics-of-isotonic-and-hypertonic-resuscitation-fluids-is-dependent-on-the-sizes-of-the-body-fluid-volumes
#21
JOURNAL ARTICLE
Robert G Hahn
BACKGROUND AND AIMS: The extracellular and intracellular fluid volumes (ECV and ICV) vary not only with age, gender, and body weight but also with the habitual intake of water. The present study examines whether the baseline variations in the ECV and ICV change the distribution and elimination of subsequently given infusion fluids. MATERIAL AND METHODS: Twenty healthy male volunteers underwent 50 infusion experiments with crystalloid fluid for which the fluid volume kinetics was calculated based on frequent measurements of the hemodilution using mixed-effects modeling software...
2023: Journal of Anaesthesiology, Clinical Pharmacology
https://read.qxmd.com/read/37523718/osmotic-demyelination-as-a-complication-of-hyponatremia-correction-a-systematic-review
#22
JOURNAL ARTICLE
Ananda Pires Bastos, Paulo Novis Rocha
BACKGROUND: Rapid correction of hyponatremia, especially when severe and chronic, can result in osmotic demyelination. The latest guideline for diagnosis and treatment of hyponatremia (2014) recommends a correction limit of 10 mEq/L/day. Our aim was to summarize published cases of osmotic demyelination to assess the adequacy of this recommendation. METHOD: Systematic review of case reports of osmotic demyelination. We included cases confirmed by imaging or pathology exam, in people over 18 years of age, published between 1997 and 2019, in English or Portuguese...
July 28, 2023: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://read.qxmd.com/read/37521749/mega-scale-desalination-efficacy-reverse-osmosis-electrodialysis-membrane-distillation-med-msf-during-covid-19-evidence-from-salinity-pretreatment-methods-temperature-of-operation
#23
JOURNAL ARTICLE
Seyed Masoud Parsa
The unprecedented situation of the COVID-19 pandemic heavily polluted water bodies whereas the presence of SARS-CoV-2, even in treated wastewater in every corner of the world is reported. The main aim of the present study is to show the effectiveness and feasibility of some well-known desalination technologies which are reverse osmosis (RO), Electrodialysis (ED), Membrane Distillation (MD), multi effect distillation (MED), and multi stage flashing (MSF) during the COVID-19 pandemic. Systems' effectiveness against the novel coronavirus based on three parameters of nasopharynx/nasal saline-irrigation, temperature of operation and pretreatment methods are evaluated...
February 2023: J Hazard Mater Adv
https://read.qxmd.com/read/37511706/a-hypertonic-seawater-nasal-irrigation-solution-containing-algal-and-herbal-natural-ingredients-reduces-viral-load-and-sars-cov-2-detection-time-in-the-nasal-cavity
#24
JOURNAL ARTICLE
Ioannis Pantazopoulos, Athanasios Chalkias, Angeliki Miziou, Michalis Spanos, Efrosyni Gerovasileiou, Erasmia Rouka, Konstantinos Gourgoulianis
Nasal irrigation is thought to decrease the viral load present in the nasal cavity. Our aim was to assess the effect of a hypertonic seawater solution [with algal and herbal natural ingredients (Sinomarin® )] on the viral load of nasopharynx in patients hospitalized with severe COVID-19 pneumonia. We conducted a prospective, randomized, controlled trial from June 2022 to December 2022. We allocated 56 patients with COVID-19 pneumonia into two groups (28 in each group)-the hypertonic seawater group [nasal irrigations with a hypertonic seawater solution (Sinomarin® ) every 4 h for 16 h per day, for two consecutive days] and the control group (no nasal irrigations)...
July 3, 2023: Journal of Personalized Medicine
https://read.qxmd.com/read/37463375/bronchiectasis-in-adult-patients-clinical-peculiarities-and-approaches-to-the-treatment
#25
JOURNAL ARTICLE
Viktoriia Rudnyk, Nataliia Chaplynska, Liubov Skrypnyk
OBJECTIVE: The aim: To perform a clinical analysis of bronchiectasis in adults, to analyze the effectiveness of nebulizer therapy with hypertonic NaCl solution with hyaluronic acid. PATIENTS AND METHODS: Materials and methods: All patients were performed clinical-functional examination (MRC dyspnea index, Sp O2, 6-minute walking test, external respiration function); calculated the index BODE, analyzed the SGRQ, studied the results of sputum. Statistical data analysis was performed using the Microsoft Excel for Microsoft 365 MSO 16...
2023: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/37452912/endocrinologists-at-work-management-of-hyponatremia-in-clinical-practice
#26
JOURNAL ARTICLE
G Arnaldi, E Arvat, A M Berton, G Corona, M Faustini Fustini, E Ferrante, P Razzore, A Peri
No abstract text is available yet for this article.
December 2023: Journal of Endocrinological Investigation
https://read.qxmd.com/read/37362105/sinonasal-irrigation-after-endoscopic-sinus-surgery-past-to-present-and-future
#27
JOURNAL ARTICLE
Ravneet Ravinder Verma, Ravinder Verma
Functional endoscopic sinus surgery (FESS) is the gold standard treatment for medically refractive chronic rhinosinusitis, aimed at removing diseased tissue and improving natural sinus drainage and aeration. Irrigation of the sinuses has been known to improve sinus mucosal health and is an essential adjunct to surgery. There are a number of methods, devices, and solutions available which are used for nasal irrigation. Neti Pot, squeeze bottle, syringe, rubber bulb and commercially available nasal sprays are some of the simpler used devices used for douching...
April 29, 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/37340592/the-added-value-of-hypertonic-saline-solution-to-furosemide-monotherapy-in-patients-with-acute-decompensated-heart-failure-a-meta-analysis-and-trial-sequential-analysis
#28
REVIEW
Carlos Diaz-Arocutipa, Jack Denegri-Galvan, Lourdes Vicent, Marcos Pariona, Mamas A Mamas, Adrian V Hernandez
We assessed the effects of hypertonic saline solution (HSS) plus furosemide versus furosemide alone in patients with acute decompensated heart failure (ADHF). We searched four electronic databases for randomized controlled trials (RCTs) until June 30, 2022. The quality of evidence (QoE) was assessed using the GRADE approach. All meta-analyses were performed using a random-effects model. A trial sequential analysis (TSA) was also conducted for intermediate and biomarker outcomes. Ten RCTs involving 3013 patients were included...
August 2023: Clinical Cardiology
https://read.qxmd.com/read/37319354/nebulised-hypertonic-saline-for-cystic-fibrosis
#29
REVIEW
Peter Wark, Vanessa M McDonald, Sherie Smith
BACKGROUND: Hypertonic saline enhances mucociliary clearance and may lessen the destructive inflammatory process in the airways. This is an update of a previously published review. OBJECTIVES: To investigate efficacy and tolerability of nebulised hypertonic saline treatment in people with cystic fibrosis (CF) compared to placebo or other treatments that enhance mucociliary clearance. SEARCH METHODS: We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Cystic Fibrosis Trials Register, comprising references identified from comprehensive electronic database searches, handsearches of relevant journals and abstract books of conference proceedings...
June 14, 2023: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/37308206/-research-progress-of-hypertonic-saline-in-early-resuscitation-of-acute-pancreatitis
#30
JOURNAL ARTICLE
Chunyu Yuan, Chunlin Yin
Local inflammatory reaction and microcirculation disturbance are the early manifestations of acute pancreatitis (AP). Studies have shown that early and reasonable fluid resuscitation of patients with AP can reduce related complications and prevent the deterioration to severe acute pancreatitis (SAP). Traditional isotonic crystalloid (such as Ringer solution) is considered to be a safe and reliable resuscitation solution, but too much and too fast infusion in the early stage of shock will increase the risk of complications such as tissue edema and abdominal compartment syndrome (ACS)...
April 2023: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/37255840/hypertonic-saline-solution-5-as-an-effective-cost-beneficial-alternative-to-normal-saline-for-wound-healing-in-patients-with-diabetic-lower-extremity-ulcers-a-randomized-controlled-trial
#31
JOURNAL ARTICLE
Bizhan Ziaian, Samad Khezri, Armin Amirian, Keivan Ranjbar, Reza Shahriarirad, Mariye Eskandari Kohnaki
BACKGROUND: Diabetic foot ulcer is among the most common complications and causes of mortality and morbidity in patients with diabetes. Herein, we propose using 5% Hypertonic Solution as an alternative to Normal Saline in treating patients with diabetic foot ulcers as an effective cost-benefit therapeutic approach. METHODS: In this clinical trial, 100 patients with diabetic foot ulcers were divided into two groups. Foot ulcer was washed and treated three times a day with the 5% hypertonic saline solution in the first group, while the second group was treated with normal saline 0...
June 2023: Journal of Diabetes and Metabolic Disorders
https://read.qxmd.com/read/37242504/molnupiravir-nirmatrelvir-ritonavir-or-sotrovimab-for-high-risk-covid-19-patients-infected-by-the-omicron-variant-hospitalization-mortality-and-time-until-negative-swab-test-in-real-life
#32
JOURNAL ARTICLE
Luca Cegolon, Riccardo Pol, Omar Simonetti, Francesca Larese Filon, Roberto Luzzati
Background . Several drugs which are easy to administer in outpatient settings have been authorized and endorsed for high-risk COVID-19 patients with mild-moderate disease to prevent hospital admission and death, complementing COVID-19 vaccines. However, the evidence on the efficacy of COVID-19 antivirals during the Omicron wave is scanty or conflicting. Methods . This retrospective controlled study investigated the efficacy of Molnupiravir or Nirmatrelvir/Ritonavir (Paxlovid® ) or Sotrovimab against standard of care (controls) on three different endpoints among 386 high-risk COVID-19 outpatients: hospital admission at 30 days; death at 30 days; and time between COVID-19 diagnosis and first negative swab test result...
May 9, 2023: Pharmaceuticals
https://read.qxmd.com/read/37166355/peripheral-intravenous-administration-of-23-4-sodium-chloride-solution-a-plea-for-caution
#33
JOURNAL ARTICLE
Brian L Erstad
No abstract text is available yet for this article.
July 21, 2023: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/37137551/acute-exercise-of-painful-muscles-does-not-reduce-the-hypoalgesic-response-in-young-healthy-women%C3%A2-a-randomized-crossover-study
#34
JOURNAL ARTICLE
Anders Mohrsen, Henrik Lund, Steven Zartov Rasmussen, Henrik Bjarke Vægter, Jonathan Vela, Simon Hansen, Steffan Wittrup McPhee Christensen
OBJECTIVES: Exercise-induced hypoalgesia (EIH) is characterized by an increase in pain threshold following acute exercise. EIH is reduced in some individuals with chronic musculoskeletal pain, although the mechanisms are unknown. It has been hypothesized that this may relate to whether exercises are performed in painful or non-painful body regions. The primary aim of this randomized experimental crossover study was to investigate whether the presence of pain per se in the exercising muscles reduced the local EIH response...
May 4, 2023: Scandinavian Journal of Pain
https://read.qxmd.com/read/37127402/topical-hypertonic-saline-as-a-treatment-for-ocular-and-nasal-hirudiniasis-in-a-dog
#35
E N Perry, C Davies, Pmg McCarthy
This case report describes ocular and nasal leech infestation (hirudiniasis) in a dog. The patient presented for a suspected ocular foreign body. The patient was sedated to allow proper examination, which revealed a leech foreign body attached to the bulbar conjunctiva adjacent to the inferotemporal limbus of the left eye. A 3.5% hypertonic saline solution was applied topically to the eye in four sequential drops, until the leech detached itself and was removed with a cotton bud. The affected eye was found to have a small corneal ulcer, a small area of scleral haemorrhage, and prominent lymphoid follicles within the third eyelid...
May 1, 2023: Australian Veterinary Journal
https://read.qxmd.com/read/37109088/evaluation-of-different-contrast-agents-for-regional-lung-perfusion-measurement-using-electrical-impedance-tomography-an-experimental-pilot-study
#36
JOURNAL ARTICLE
Thomas Muders, Benjamin Hentze, Steffen Leonhardt, Christian Putensen
Monitoring regional blood flow distribution in the lungs appears to be useful for individually optimizing ventilation therapy. Electrical impedance tomography (EIT) can be used at the bedside for indicator-based regional lung perfusion measurement. Hypertonic saline is widely used as a contrast agent but could be problematic for clinical use due to potential side effects. In five ventilated healthy pigs, we investigated the suitability of five different injectable and clinically approved solutions as contrast agents for EIT-based lung perfusion measurement...
April 7, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37079938/safety-of-peripheral-3-hypertonic-saline-bolus-administration-for-neurologic-emergency
#37
JOURNAL ARTICLE
Caitlin S Brown, Alejandro A Rabinstein, Yanjun Zhao, Erin D Wieruszewski
BACKGROUND/OBJECTIVE: Hypertonic sodium chloride (HTS) is used for emergent treatment of acute cerebral edema and other neurologic emergencies. Central access is not commonly available in emergent situations and 3% HTS is utilized peripherally. Many studies have shown the safety of its administration at rates up to 75 mL/h, but there is a lack of data to establish the safety of peripherally administered, rapid bolus dosing in emergent situations. The objective of this study is to describe the safety of rapid, peripherally administered (≥ 250 mL/h) 3% HTS for neurologic emergencies...
July 2023: American Journal of Emergency Medicine
https://read.qxmd.com/read/37033701/a-step-by-step-guide-for-the-diagnosis-and-management-of-hyponatraemia-in-patients-with-stroke
#38
REVIEW
Fotios Barkas, Georgia Anastasiou, George Liamis, Haralampos Milionis
Hyponatraemia is common in patients with stroke and associated with adverse outcomes and increased mortality risk. The present review presents the underlying causes and provides a thorough algorithm for the diagnosis and management of hyponatraemia in stroke patients. Concomitant diseases and therapies, such as diabetes, chronic kidney disease and heart failure, along with diuretics, antidepressants and proton pump inhibitors are the most common causes of hyponatraemia in community. In the setting of acute stroke, the emergence of hyponatraemia might be attributed to the administration of hypotonic solutions and drugs (ie...
2023: Therapeutic Advances in Endocrinology and Metabolism
https://read.qxmd.com/read/37014057/nebulised-hypertonic-saline-solution-for-acute-bronchiolitis-in-infants
#39
REVIEW
Linjie Zhang, Raúl Andrés Mendoza-Sassi, Claire E Wainwright, Alex Aregbesola, Terry P Klassen
BACKGROUND: Airway oedema (swelling) and mucus plugging are the principal pathological features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution (≥ 3%) may reduce these pathological changes and decrease airway obstruction. This is an update of a review first published in 2008, and updated in 2010, 2013, and 2017. OBJECTIVES: To assess the effects of nebulised hypertonic (≥ 3%) saline solution in infants with acute bronchiolitis...
April 4, 2023: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/37007979/electroencephalographic-patterns-in-a-mechanically-ventilated-cat-with-permethrin-intoxication
#40
Samuel Okonji, Cecilia Bulgarelli, Roberta Troìa, Alessandra Pontiero, Armando Foglia, Massimo Giunti, Gualtiero Gandini
CASE SUMMARY: A 1-year-old male castrated domestic shorthair cat was presented in a condition of status epilepticus following incidental permethrin spot-on administration by its owner. General anaesthesia and mechanical positive pressure control ventilation were necessary to control the epileptic seizures and a progressive condition of hypoventilation. The cat was managed with an intravenous constant rate infusion of midazolam, propofol and ketamine associated with a low-dose intravenous lipid emulsion...
2023: JFMS Open Reports
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