keyword
https://read.qxmd.com/read/38536052/spirituality-and-people-with-psychosis-a-content-analysis-of-influential-primetime-television-programs
#1
JOURNAL ARTICLE
David R Hodge, Patricia R Turner
OBJECTIVE: This mixed methods study examined depictions of spirituality among people with psychosis in influential television programming. Spirituality is a central strength for many people with psychosis. Yet, despite the important role media plays in shaping perceptions, little research has examined the intersection between spirituality and psychosis in popular media. METHODS: To address this gap, we conducted a content analysis of the 50 most viewed primetime fictional television shows over a 10-year period as determined by the Nielsen rating organization...
March 27, 2024: International Journal of Psychiatry in Medicine
https://read.qxmd.com/read/38529082/identification-of-psychosis-risk-and-diagnosis-of-first-episode-psychosis-advice-for-clinicians
#2
REVIEW
Nancy B Lundin, Alexandra M Blouin, Henry R Cowan, Aubrey M Moe, Heather M Wastler, Nicholas J K Breitborde
Early detection of psychotic-spectrum disorders among adolescents and young adults is crucial, as the initial years after psychotic symptom onset encompass a critical period in which psychosocial and pharmacological interventions are most effective. Moreover, clinicians and researchers in recent decades have thoroughly characterized psychosis-risk syndromes, in which youth are experiencing early warning signs indicative of heightened risk for developing a psychotic disorder. These insights have created opportunities for intervention even earlier in the illness course, ideally culminating in the prevention or mitigation of psychosis onset...
2024: Psychology Research and Behavior Management
https://read.qxmd.com/read/38516103/comparing-interventions-for-early-psychosis-a-systematic-review-and-component-network-meta-analysis
#3
JOURNAL ARTICLE
Ryan Williams, Edoardo G Ostinelli, Joel Agorinya, Amedeo Minichino, Franco De Crescenzo, Daniel Maughan, Stephen Puntis, Charlotte Cliffe, Ayse Kurtulmus, Belinda R Lennox, Andrea Cipriani
BACKGROUND: 'Early Intervention in Psychosis' (EIP) services have been associated with improved outcomes for early psychosis. However, these services are heterogeneous and many provide different components of treatment. The impact of this variation on the sustained treatment effects is unknown. METHODS: We performed a systematic review and component network meta-analysis (cNMA) of randomised controlled trials (RCTs) that compared specialised intervention services for early psychosis...
April 2024: EClinicalMedicine
https://read.qxmd.com/read/38512852/a-lifetime-of-mental-health-treatments-for-people-with-schizophrenia-update-and-narrative-review
#4
REVIEW
Lynn E DeLisi
PURPOSE OF REVIEW: To provide a summary of the most up-to-date thoughts about treatment for schizophrenia at different stages of illness. RECENT FINDINGS: The use of Coordinated Specialty Care clinics has arisen as the standard for early on in the treatment of psychosis, providing the notion that recovery is possible. New medications that do not depend on postsynaptic dopamine receptor blockade are soon becoming available. SUMMARY: A focus should be made by clinicians to personalize treatment plans for each patient who has the possibility of being diagnosed with a primary psychosis and the plan should be to predict outcomes based on biological markers that include genetic vulnerability, early psychosocial combined with pharmacological treatments as needed and then a plan to determine or maintain treatments going forward into the future...
May 1, 2024: Current Opinion in Psychiatry
https://read.qxmd.com/read/38470162/cognitive-behavioural-therapy-added-to-standard-care-for-first-episode-and-recent-onset-psychosis
#5
REVIEW
Susanna Franziska Mayer, Ciaran Corcoran, Liam Kennedy, Stefan Leucht, Irene Bighelli
BACKGROUND: Cognitive behavioural therapy (CBT) can be effective in the general population of people with schizophrenia. It is still unclear whether CBT can be effectively used in the population of people with a first-episode or recent-onset psychosis. OBJECTIVES: To assess the effects of adding cognitive behavioural therapy to standard care for people with a first-episode or recent-onset psychosis. SEARCH METHODS: We conducted a systematic search on 6 March 2022 in the Cochrane Schizophrenia Group's Study-Based Register of Trials, which is based on CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, PubMed, ClinicalTrials...
March 12, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38441824/early-psychosis-intervention-and-primary-care-a-mixed-methods-study-of-family-physician-knowledge-attitudes-preferences-and-needs
#6
JOURNAL ARTICLE
Brooke Carter, Rebecca Rodrigues, Jordan Edwards, Saadia Hameed Jan, Bridget L Ryan, Richard G Booth, Suzanne Archie, Kelly K Anderson
Family physicians (FPs) play an important but underappreciated role in the pathways to care for people with early psychosis. We conducted a mixed-methods study to describe the knowledge, attitudes, preferences, and needs of FPs towards the recognition and management of early psychosis. We sent a cross-sectional postal survey to a random sample of FPs in Ontario, Canada, and conducted in-depth qualitative interviews with twenty. FPs were generally aware of important early psychosis symptoms, however, there were some knowledge gaps...
March 5, 2024: Community Mental Health Journal
https://read.qxmd.com/read/38418971/an-integrated-primary-care-service-to-reduce-cardiovascular-disease-risk-in-people-with-severe-mental-illness-primrose-a-thematic-analysis-of-its-acceptability-feasibility-and-implementation
#7
JOURNAL ARTICLE
Philippa Shaw, Annabel Mifsud, David Osborn, Nitisha Nahata, Cerdic Hall, Ian Prenelle, Danielle Lamb
BACKGROUND: Cardiovascular disease among patients with severe mental illness in England is a major preventable contributor to premature mortality. To address this, a nurse and peer-coach delivered service (Primrose-A) was implemented in three London general practices from 2019 (implementation continued during COVID-19). This study aimed to conduct interviews with patient and staff to determine the acceptability of, and experiences with, Primrose-A. METHODS: Semi-structured audio-recorded interviews with eight patients who had received Primrose-A, and 3 nurses, 1 GP, and 1 peer-coach who had delivered Primrose-A in three London-based GP surgeries were conducted...
February 28, 2024: BMC Health Services Research
https://read.qxmd.com/read/38298788/phencyclidine-disrupts-neural-coordination-and-cognitive-control-by-dysregulating-translation
#8
JOURNAL ARTICLE
Eun Hye Park, Hsin-Yi Kao, Hussam Jourdi, Milenna T van Dijk, Simón Carrillo-Segura, Kayla W Tunnell, Jeffrey Gutierrez, Emma J Wallace, Matthew Troy-Regier, Basma Radwan, Edith Lesburguères, Juan Marcos Alarcon, André A Fenton
BACKGROUND: Phencyclidine (PCP) causes psychosis, is abused with increasing frequency, and was extensively used in antipsychotic drug discovery. PCP discoordinates hippocampal ensemble action potential discharge and impairs cognitive control in rats, but how this uncompetitive NMDA receptor (NMDAR) antagonist impairs cognition remains unknown. METHODS: The effects of PCP were investigated on hippocampal CA1 ensemble action potential discharge in vivo in urethane-anesthetized rats and during awake behavior in mice, on synaptic responses in ex vivo mouse hippocampus slices, in mice on a hippocampus-dependent active place avoidance task that requires cognitive control, and on activating the molecular machinery of translation in acute hippocampus slices...
January 2024: Biol Psychiatry Glob Open Sci
https://read.qxmd.com/read/38274116/cognitive-behavioural-therapy-for-the-treatment-of-schizophrenia-spectrum-disorders-an-umbrella-review-of-meta-analyses-of-randomised-controlled-trials
#9
REVIEW
Steven Berendsen, Silke Berendse, Jeanne van der Torren, Jentien Vermeulen, Lieuwe de Haan
BACKGROUND: Cognitive behavioural therapy (CBT) forms the standard psychotherapy for schizophrenia spectrum disorders (SSD). We aimed to summarize and evaluate the evidence on the effectiveness of CBT for SSD. METHODS: In this umbrella review, we searched PubMed, Embase, Cochrane Database, and PsychInfo, for meta-analyses of randomised controlled trials (RCTs) of CBT in SSD published between database inception up to Aug 18, 2023. Inclusion criteria were RCTs investigating individually provided CBT in a population of patients with SSD, compared to either standard care, treatment as usually, or any other psychosocial therapies...
January 2024: EClinicalMedicine
https://read.qxmd.com/read/38272671/-phencyclidine-like-abuse-liability-and-psychosis-like-neurocognitive-effects-of-novel-arylcyclohexylamine-drugs-of-abuse-in-rodents
#10
JOURNAL ARTICLE
Hannah E Shaw, Dylan R Patel, Brenda M Gannon, Lauren R Fitzgerald, Theresa M Carbonaro, Chad R Johnson, William E Fantegrossi
Abuse of novel arylcyclohexylamines (ACX) poses risks for toxicities including adverse neurocognitive effects. In vivo effects of ring-substituted analogs of phencyclidine (PCP), eticyclidine (PCE), and ketamine are understudied. Adult male NIH Swiss mice were used to assess locomotor effects of PCP and its 3-OH, 3-MeO, 3-Cl and 4-MeO analogs; PCE and its 3-OH and 3-MeO analogs; and ketamine and its deschloro and 2F-deschloro analogs, in comparison to those of methamphetamine (METH), 3,4-methylenedioxymethamphetamine (MDMA), and two benzofuran analogs of MDMA...
January 25, 2024: Journal of Pharmacology and Experimental Therapeutics
https://read.qxmd.com/read/38092451/models-of-shared-care-for-the-management-of-psychotic-disorder-after-first-diagnosis-in-ontario
#11
JOURNAL ARTICLE
Joshua C Wiener, Rebecca Rodrigues, Jennifer N S Reid, Kelly K Anderson
OBJECTIVE: To describe the provision of care for young people following first diagnosis of psychotic disorder. DESIGN: Retrospective cohort study using health administrative data. SETTING: Ontario. PARTICIPANTS: People aged 14 to 35 years with a first diagnosis of nonaffective psychotic disorder in Ontario between 2005 and 2015 (N=39,449). MAIN OUTCOME MEASURES: Models of care, defined by psychosis-related service contacts with primary care physicians and psychiatrists during the 2 years after first diagnosis of psychotic disorder...
December 2023: Canadian Family Physician Médecin de Famille Canadien
https://read.qxmd.com/read/38036458/access-to-a-regular-primary-care-physician-among-young-people-with-early-psychosis-in-ontario-canada
#12
JOURNAL ARTICLE
Rebecca Rodrigues, Jennifer N S Reid, Joshua C Wiener, Suzanne Archie, Richard G Booth, Chiachen Cheng, Arlene G MacDougall, Lena Palaniyappan, Bridget L Ryan, Aristotle Voineskos, Paul Kurdyak, Saadia Hameed Jan, Kelly K Anderson
AIM: Access to a primary care physician in early psychosis facilitates help-seeking and engagement with psychiatric treatment. We examined access to a regular primary care physician in people with early psychosis, compared to the general population, and explored factors associated with access. METHODS: Using linked health administrative data from Ontario (Canada), we identified people aged 14-35 years with a first diagnosis of nonaffective psychotic disorder (n = 39 449; 2005-2015)...
November 30, 2023: Early Intervention in Psychiatry
https://read.qxmd.com/read/38025474/predictors-of-positive-outcomes-from-early-intervention-in-psychosis-protocol-for-a-national-retrospective-cohort-study
#13
JOURNAL ARTICLE
Ryan Williams, Ed Penington, Veenu Gupta, Apostolos Tsiachristas, Paul French, Belinda Lennox, Alex Bottle, Mike J Crawford
BACKGROUND: Psychotic disorders are severe and prevalent mental health conditions associated with long-term disability, reduced quality of life, and substantial economic costs. Early Intervention in Psychosis (EIP) services aim to provide timely and comprehensive treatment for psychotic disorders, and EIP service input is associated with improved outcomes. However, there is limited understanding of the specific components of EIP care that contribute to these improvements. There is significant nationwide variability in the commissioning and delivery of EIP, with individuals receiving different packages of components from different services...
2023: Frontiers in Psychiatry
https://read.qxmd.com/read/37943446/implementation-of-an-adapted-fidelity-scale-for-pennsylvania-coordinated-specialty-care-programs-for-first-episode-psychosis
#14
JOURNAL ARTICLE
Megan B E Jumper, Bess Rose Friedman, Emily M Becker-Haimes, Fanghong Dong, Christian G Kohler, Irene Hurford, Monica E Calkins
Coordinated Specialty Care (CSC) is an evidence-based model for early intervention of first episode psychosis (FEP). Monitoring fidelity to CSC models is essential for proper evaluation of program outcomes and quality improvement. To address variability across CSC programs and fidelity assessment-associated burden, an adapted fidelity scale was developed and implemented statewide in Pennsylvania. This report describes the design and preliminary performance of the adapted scale. The Pennsylvania FEP Fidelity Scale (PA-FEP-FS) assesses adherence to the CSC model by focusing on essential model components of other established fidelity scales, in tandem with program evaluation data...
November 9, 2023: Prevention Science: the Official Journal of the Society for Prevention Research
https://read.qxmd.com/read/37934551/initiation-of-extended-release-depot-buprenorphine-in-a-patient-subject-to-a-community-treatment-order-for-both-antipsychotic-and-opioid-agonist-treatments
#15
JOURNAL ARTICLE
Joel Pidutti, Ari B Cuperfain, Eric Solway, Virginia Duff, Erin Lurie
Opioid use disorder (OUD) and schizophrenia are commonly comorbid, and patient outcomes are improved when these conditions are managed concurrently. Medication for OUD such as methadone and buprenorphine are treatments for OUD, yet psychosis introduces additional challenges in retaining patients in care. Extended-release depot buprenorphine is an emerging option for the treatment of moderate-to-severe OUD, and it may provide certain benefits in patients with concurrent OUD and psychosis. We present the case of a 32-year-old man with schizophrenia, traumatic brain injury, and OUD with a history of multiple opioid-related overdoses, followed by an assertive community treatment team, and subject to a community treatment order for both his primary psychotic disorder and OUD treatments...
November 2023: Journal of Addiction Medicine
https://read.qxmd.com/read/37854388/successful-ingredients-of-effective-collaborative-care-programs-in-low-and-middle-income-countries-a-rapid-review
#16
REVIEW
Jessica Whitfield, Shanise Owens, Amritha Bhat, Bradford Felker, Teresa Jewell, Lydia Chwastiak
Integrating mental health care in primary healthcare settings is a compelling strategy to address the mental health treatment gap in low- and middle-income countries (LMICs). Collaborative Care is the integrated care model with the most evidence supporting its effectiveness, but most research has been conducted in high-income countries. Efforts to implement this complex multi-component model at scale in LMICs will be enhanced by understanding the model components that have been effective in LMIC settings. Following Cochrane Rapid Reviews Methods Group recommendations, we conducted a rapid review to identify studies of the effectiveness of Collaborative Care for priority adult mental disorders of mhGAP (mood and anxiety disorders, psychosis, substance use disorders and epilepsy) in outpatient medical settings in LMICs...
2023: Global Mental Health
https://read.qxmd.com/read/37814998/understanding-the-role-of-the-nmda-receptor-subunit-glun2d-in-mediating-nmda-receptor-antagonist-induced-behavioral-disruptions-in-male-and-female-mice
#17
JOURNAL ARTICLE
Chitra Vinnakota, Anna Schroeder, Xin Du, Kazutaka Ikeda, Soichiro Ide, Masayoshi Mishina, Matthew Hudson, Nigel Charles Jones, Suresh Sundram, Rachel Anne Hill
Noncompetitive NMDA receptor (NMDAR) antagonists like phencyclidine (PCP) and ketamine cause psychosis-like symptoms in healthy humans, exacerbate schizophrenia symptoms in people with the disorder, and disrupt a range of schizophrenia-relevant behaviors in rodents, including hyperlocomotion. This is negated in mice lacking the GluN2D subunit of the NMDAR, suggesting the GluN2D subunit mediates the hyperlocomotor effects of these drugs. However, the role of GluN2D in mediating other schizophrenia-relevant NMDAR antagonist-induced behavioral disturbances, and in both sexes, is unclear...
October 10, 2023: Journal of Neuroscience Research
https://read.qxmd.com/read/37802615/understanding-the-burden-of-mental-and-physical-health-disorders-on-families-findings-from-the-saudi-national-mental-health-survey
#18
JOURNAL ARTICLE
Haya S Zedan, Lisa Bilal, Sanaa Hyder, Mohammad Talal Naseem, Marya Akkad, Abdulhameed Al-Habeeb, Abdullah S Al-Subaie, Yasmin Altwaijri
OBJECTIVE: To assess prevalence and correlation of factors of family burden associated with mental and physical disorders in the general population of Saudi Arabia. SETTING AND PARTICIPANTS: A secondary analysis of data from the Saudi National Mental Health Survey (SNMHS). OUTCOME MEASURES: Mental and physical health disorders of first-degree relatives and objective (time, financial) and subjective (distress, embarrassment) family burden. RESULTS: We found significant caregiver burden for family members with mental health disorders...
October 6, 2023: BMJ Open
https://read.qxmd.com/read/37742702/automated-virtual-reality-cognitive-therapy-versus-virtual-reality-mental-relaxation-therapy-for-the-treatment-of-persistent-persecutory-delusions-in-patients-with-psychosis-thrive-a-parallel-group-single-blind-randomised-controlled-trial-in-england-with-mediation
#19
JOURNAL ARTICLE
Daniel Freeman, Rachel Lister, Felicity Waite, Ushma Galal, Ly-Mee Yu, Sinéad Lambe, Ariane Beckley, Emily Bold, Lucy Jenner, Rowan Diamond, Miriam Kirkham, Eve Twivy, Chiara Causier, Lydia Carr, Simone Saidel, Rebecca Day, Alejandro Beacco, Aitor Rovira, Annabel Ivins, Ryan Nah, Mel Slater, David M Clark, Laina Rosebrock
BACKGROUND: Persecutory delusions are a major psychiatric problem that often do not respond sufficiently to standard pharmacological or psychological treatments. We developed a new brief automated virtual reality (VR) cognitive treatment that has the potential to be used easily in clinical services. We aimed to compare VR cognitive therapy with an alternative VR therapy (mental relaxation), with an emphasis on understanding potential mechanisms of action. METHODS: THRIVE was a parallel-group, single-blind, randomised controlled trial across four UK National Health Service trusts in England...
November 2023: Lancet Psychiatry
https://read.qxmd.com/read/37719696/left-frontal-lobe-glioblastoma-multiforme-masquerading-as-psychosis-a-case-report
#20
Bee Zhen Ng, Jeremiah Sunderaj Peter, Sze Hung Chua
Brain tumours often present with a variety of early subtle, non-specific symptoms. This can obscure an organic origin of the illness, which deters timely referral and management. We report a rare case of psychosis in a patient with a left frontal lobe tumour, preceded by 2 months of lethargy and word- finding difficulty with minimal neurological deficits, who was referred to our psychiatric unit from a primary care facility. Blood investigation findings including tumour marker levels were normal. Prompt neuroimaging revealed a left frontal lobe lesion with findings indicating a glioblastoma...
2023: Malaysian Family Physician
keyword
keyword
119930
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.