Daniel Freeman, Rachel Lister, Felicity Waite, Ushma Galal, Ly-Mee Yu, Sinéad Lambe, Ariane Beckley, Emily Bold, Lucy Jenner, Rowan Diamond, Miriam Kirkham, Eve Twivy, Chiara Causier, Lydia Carr, Simone Saidel, Rebecca Day, Alejandro Beacco, Aitor Rovira, Annabel Ivins, Ryan Nah, Mel Slater, David M Clark, Laina Rosebrock
BACKGROUND: Persecutory delusions are a major psychiatric problem that often do not respond sufficiently to standard pharmacological or psychological treatments. We developed a new brief automated virtual reality (VR) cognitive treatment that has the potential to be used easily in clinical services. We aimed to compare VR cognitive therapy with an alternative VR therapy (mental relaxation), with an emphasis on understanding potential mechanisms of action. METHODS: THRIVE was a parallel-group, single-blind, randomised controlled trial across four UK National Health Service trusts in England...
November 2023: Lancet Psychiatry