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https://www.readbyqxmd.com/read/28081371/gwas-identifies-new-loci-for-painful-temporomandibular-disorder
#1
A E Sanders, D Jain, T Sofer, K F Kerr, C C Laurie, J R Shaffer, M L Marazita, L M Kaste, G D Slade, R B Fillingim, R Ohrbach, W Maixner, T Kocher, O Bernhardt, A Teumer, C Schwahn, K Sipilä, R Lähdesmäki, M Männikkö, P Pesonen, M Järvelin, C M Rizzatti-Barbosa, C B Meloto, M Ribeiro-Dasilva, L Diatchenko, P Serrano, S B Smith
Temporomandibular disorder (TMD) is a musculoskeletal condition characterized by pain and reduced function in the temporomandibular joint and/or associated masticatory musculature. Prevalence in the United States is 5% and twice as high among women as men. We conducted a discovery genome-wide association study (GWAS) of TMD in 10,153 participants (769 cases, 9,384 controls) of the US Hispanic Community Health Study/Study of Latinos (HCHS/SOL). The most promising single-nucleotide polymorphisms (SNPs) were tested in meta-analysis of 4 independent cohorts...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28068790/temporomandibular-disorders-old-ideas-and-new-concepts
#2
Thomas List, Rigmor Højland Jensen
Background Temporomandibular disorders (TMD) is an umbrella term for pain and dysfunction involving the masticatory muscles and the temporomandibular joints (TMJs). TMD is the most common orofacial pain condition. Its prominent features include regional pain in the face and preauricular area, limitations in jaw movement, and noise from the TMJs during jaw movements. TMD affects up to 15% of adults and 7% of adolescents. Chronic pain is the overwhelming reason that patients with TMD seek treatment. TMD can associate with impaired general health, depression, and other psychological disabilities, and may affect the quality of life of the patient...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28065754/mechanisms-involved-in-antinociception-induced-by-a-polysulfated-fraction-from-seaweed-gracilaria-cornea-in-the-temporomandibular-joint-of-rats
#3
Chistiane Oliveira Coura, Hellíada Vasconcelos Chaves, Danielle Rocha do Val, Lorena Vasconcelos Vieira, Felipe Dantas Silveira, Fernanda Maxcynne Lino Dos Santos Lopes, Francisco Isaac Fernandes Gomes, Annyta Fernandes Frota, Ricardo Basto Souza, Juliana Trindade Clemente-Napimoga, Mirna Marques Bezerra, Norma Maria Barros Benevides
Temporomandibular disorder is a common clinical condition involving pain in the temporomandibular joint (TMJ) region. This study assessed the antinociceptive effects of a polysulfated fraction from the red seaweed Gracilaria cornea (Gc-FI) on the formalin-induced TMJ hypernociception in rats and investigated the involvement of different mechanisms. Male Wistar rats were pretreated with injection (sc) of saline or Gc-FI 1h before intra- TMJ injection of formalin to evaluate the nociception. The results showed that pretreatment with Gc-FI significantly reduced formalin-induced nociceptive behavior...
January 5, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28063976/effect-of-jaw-opening-exercise-on-prevention-of-temporomandibular-disorders-pain-associated-with-oral-appliance-therapy-in-obstructive-sleep-apnea-patients-a-randomized-double-blind-placebo-controlled-trial
#4
Hiroyuki Ishiyama, Shusuke Inukai, Akira Nishiyama, Masayuki Hideshima, Shuhei Nakamura, Meiyo Tamaoka, Yasunari Miyazaki, Kenji Fueki, Noriyuki Wakabayashi
PURPOSE: There are no studies on the prevention of temporomandibular joint and/or masticatory muscle pain (TMD pain) associated with oral appliance (OA) therapy in patients with obstructive sleep apnea (OSA). The aim of this study was to determine the effect of jaw-opening exercise on TMD pain associated with OA therapy in OSA patients. METHODS: Twenty-five OSA patients without pain-related TMD were consecutively enrolled into a two-arm, randomized, double-blind, placebo-controlled trial...
January 4, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/28059446/elimination-of-pain-improves-specificity-of-clinical-diagnostic-criteria-for-adult-chronic-rhinosinusitis
#5
Scott D Hirsch, Evan R Reiter, Laurence J DiNardo, Wen Wan, Theodore A Schuman
OBJECTIVE: Determine whether the elimination of pain improves accuracy of clinical diagnostic criteria for adult chronic rhinosinusitis. STUDY DESIGN: Retrospective cohort study. METHODS: History, symptoms, nasal endoscopy, and computed tomography (CT) results were analyzed for 1,186 adults referred to an academic otolaryngology clinic with presumptive diagnosis of chronic rhinosinusitis. Clinical diagnosis was rendered using the 1997 Rhinosinusitis Taskforce (RSTF) Guidelines and a modified version eliminating facial pain, ear pain, dental pain, and headache...
January 6, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28057402/consultation-with-a-specialized-pain-clinic-reduces-pain-after-oral-and-maxillofacial-surgery
#6
Eva-Maria Dietrich, Norbert Griessinger, Friedrich Wilhelm Neukam, Tilo Schlittenbauer
PURPOSE: Postoperative pain management is important for improved patient care. Our primary objective was to investigate the effect of analgesic treatment adaptation by the pain clinic on postoperative pain relief at an oral and maxillofacial surgery department. Additionally, we aimed to present patients' pain characteristics and the administered analgesic treatment. MATERIALS AND METHODS: A total of 128 patients treated at our clinic in the period 2012-2015 who required analgesic treatment adaptation by our pain clinic were included...
December 14, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28054261/effectiveness-of-low-level-laser-therapy-on-pain-intensity-pressure-pain-threshold-and-sf-mpq-indexes-of-women-with-myofascial-pain
#7
Laís Valencise Magri, Vinícius Almeida Carvalho, Flávia Cássia Cabral Rodrigues, César Bataglion, Christie Ramos Andrade Leite-Panissi
Women with temporomandibular disorders (TMD) frequently report pain areas in body regions. This process is associated with central sensitization phenomena, present in chronic pain. The low-level laser therapy (LLLT) has been reported as a therapeutic option for the painful TMD treatment. The aim of this study was to analyze the effect of LLLT on pain intensity (visual analogue scale, VAS), pain sensitivity in orofacial and corporal points (pressure pain threshold, PPT), and on Short Form-McGill Pain Questionnaire (SF-MPQ) indexes of women with myofascial pain (subtype of muscle TMD)...
January 4, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28050980/prevalence-and-severity-of-temporomandibular-disorders-among-undergraduate-medical-students-in-association-with-khat-chewing
#8
Mohammed M Al Moaleem, Abdulmajeed S Okshah, Ahid A Al-Shahrani, Abdulkhaliq Ali F Alshadidi, Fawzia I Shaabi, Abdulaziz H Mobark, Khurshid A Mattoo
INTRODUCTION: The aim of this study was to assess the prevalence and severity of temporomandibular joint disorders (TMDs) among undergraduate medical students in the presence of khat chewing over a period of time. MATERIALS AND METHODS: Totally, 186 medical college students (age < 20 years) were randomly selected for the present study. The study subjects were divided into two groups according to age, under 20 and above 20 years. The study was based on Fonseca's anamnestic index and its questionnaire, which is composed of 10 questions and classifies the severity of TMDs...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28043747/osteoblastoma-of-the-temporal-articular-tubercle-misdiagnosed-as%C3%A2-a-temporomandibular-joint-disorder
#9
J Emanuelsson, C M Allen, K Rydin, M Sjöström
The case of a 17-year-old female with a benign osteoblastoma in the temporomandibular joint (TMJ) is reported. The patient had a 2.5-year history of reduced mouth opening accompanied by tenderness and swelling in the left TMJ. Initial treatment included stabilization of the occlusion with a splint, jaw exercises, and analgesics. At first the patient's symptoms decreased, but they then increased 18 months later, prompting a cone beam computed tomography (CBCT) evaluation of the joint. The radiographic findings showed a somewhat ill-defined, radiolucent, expansile lesion containing small scattered calcifications located in the temporal articular tubercle...
December 30, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28029069/effectiveness-of-osteopathic-manipulative-treatment-versus-osteopathy-in-the-cranial-field-in-temporomandibular-disorders-a-pilot-study
#10
Christina Gesslbauer, Nadja Vavti, Mohammad Keilani, Michael Mickel, Richard Crevenna
PURPOSE: Temporomandibular disorders are a common musculoskeletal condition causing severe pain, physical and psychological disability. The effect and evidence of osteopathic manipulative treatment and osteopathy in the cranial field is scarce and their use are controversial. The purpose of this pilot study was to evaluate the effectiveness of osteopathic manipulative treatment and osteopathy in the cranial field in temporomandibular disorders. METHODS: A randomized clinical trial in patients with temporomandibular disorders was performed...
December 28, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28005732/assessment-of-the-relationship-between-clinicophysiologic-and-magnetic-resonance-imaging-findings-of-the-temporomandibular-disorder-patients
#11
Salih Onur Basat, Mehmet Surmeli, Oguzhan Demirel, Fatih Ceran, Funda Akoz Saydam, Karaca Basaran
Temporomandibular joint disorders (TMJDs) are a complex group of disorders that comprise dysfunctions of the temporomandibular joint (TMJ). In this study, we analyzed the objective and subjective findings of the TMJD patients by using Helkimo anamnesis (Ai) and clinical dysfunction (Di) indices, and tried to document a relation between these findings and magnetic resonance imaging (MRI) results.Ninety-eight patients who were admitted to our clinic were included in the study. The clinical evaluation was performed by using Ai, an 8-question-survey based on the objective symptoms of patients; Di, concluded as the score of 5 objective measurements of physical examination...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28000839/il-1%C3%AE-impedes-the-chondrogenic-differentiation-of-synovial-fluid-mesenchymal-stem-cells-in-the-human-temporomandibular-joint
#12
Wenjing Liu, Yangpeng Sun, Yiqing He, Hong Zhang, Youhua Zheng, Yu Yao, Zhiguang Zhang
Mesenchymal stem cell-based therapy has great therapeutic potential for temporomandibular joint (TMJ) cartilage repair. However, the behavior of mesenchymal stem cells in the inflammatory milieu following their delivery remains poorly understood. Synovial fluid-derived mesenchymal stem cells (SFMSCs) are a promising resource for TMJ cartilage repair, as they are easily obtained from patients with TMJ disorders (TMD). In this study, we obtained SFMSCs from patients with TMD and expanded them in vitro; we then stimulated the cells with interleukin (IL)‑8, IL-1β, IL-6, IL-10, tumor necrosis factor (TNF)-α and IL-12p...
February 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/27987512/-diagnosis-and-treatment-of-diffuse-tenosynovial-giant-cell-tumor-arising-from-temporomandibular-joints
#13
J H Meng, Y X Guo, H Y Luo, C B Guo, X C Ma
OBJECTIVE: To retrospectively analyze the clinical features, treatment and prognosis to the diffuse tenosynovial giant cell tumor (D-TSGCT) arising from the temporomandibular joint (TMJ), and to give a reference for the early diagnosis and treatment of this disease. METHODS: In this study, 15 patients finally diagnosed as D-TSGCT of TMJ histopathologically at the Peking University Hospital of Stomatology from October 2003 to August 2015 were selected and reviewed...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27978909/-certain-experiences-in-sequential-treatment-of-occlusal-reconstruction
#14
H Y Deng, Z T Zhang
Occlusal reconstruction is a complex sequential treatment. The treatment may involve changes in occlusal vertical dimension and the full dental arch occlusal surface reconstruction. In this paper, we discussed the most concerned aspects of prosthodontists during the occlusal reconstruction sequential treatment, how to determine the suitable occlusal vertical dimension, rebuilding of occlusal plane, and consideratiom of temporomandibular joint disorders during reconstruction treatment. The prosthodontists should adopt the multidisciplinary collaboration mode of thinking in analysis, design, treatment, and restoration processes, regarding patients' individual characteristic through the occlusal reconstruction sequential treatment, and to reach healthy, functional, aesthetic outcome eventually...
December 9, 2016: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/27973938/anesthetic-management-of-a-patient-with-ehlers-danlos-syndrome
#15
Naohiro Ohshita, Masahiko Kanazumi, Kaname Tsuji, Hiroaki Yoshida, Shosuke Morita, Yoshihiro Momota, Yasuo M Tsutsumi
We describe the case of a 37-year-old woman who had been diagnosed with Ehlers-Danlos syndrome (EDS) 4 years earlier and was scheduled to undergo removal of synovial chondromatosis in the temporomandibular joint. EDS is a heritable connective tissue disorder and has 6 types. In this case, the patient was classified into EDS hypermobility type. The major clinical feature of this type is joint hypermobility. The patient had sprain or subluxation of the elbows and ankles and dislocation of the knees. Anticipated problems during general anesthesia would be affected by the disease type...
2016: Anesthesia Progress
https://www.readbyqxmd.com/read/27973713/subjects-with-temporomandibular-joint-disk-displacement-do-not-feature-any-peculiar-changes-in-body-posture
#16
T Rocha, M A Castro, L Guarda-Nardini, D Manfredini
BACKGROUND: The presence of body posture changes among patients with temporomandibular disorders (TMD) has been a controversial topic in dentistry. Based on that, the aim of this study was to assess postural features of pain-free subjects with internal derangement of the temporomandibular joint (TMJ), viz., disk displacement, when compared to subjects with normal disk position. MATERIALS AND METHODS: 21 subjects with unilateral, pain-free TMJ disk displacement (DD) and 21 subjects without any TMD signs of symptoms were assessed for body posture changes by means of posturographic evaluation of several body segments and postural balance reactions through the center of mass during jaw movements using a balance platform...
December 14, 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/27957273/electromyographic-biofeedback-training-for-reducing-muscle-pain-and-tension-on-masseter-and-temporal-muscles-a-pilot-study
#17
Laura Criado, Antonio de La Fuente, Margarita Heredia, Javier Montero, Alberto Albaladejo, José-María Criado
BACKGROUND: Due to the absence of agreement about an effective unified treatment for temporomandibular disorders, non-invasive therapies such as EMG-biofeedback generate a greater interest. Furthermore, most studies to the present show methodological deficiencies that must be solved in the future, which makes important to emphasize this line of studies. MATERIAL AND METHODS: Fourteen patients were selected for this case series study, and replied to a questionnaire concerning awareness of bruxism, painful muscles, and muscle tension...
December 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27930895/osteoarthrosis-of-temporomandibular-joint-related-to-the-defects-of-posterior-dentition-a-retrospective-study
#18
Jitka Levorová, Vladimír Machoň, Anasuya Guha, René Foltán
Osteoarthrosis (OA) of temporomandibular joint (TMJ) is a progressive degenerative disease, gradually affecting cartilage, synovial membrane and bone structures. OA of TMJ clinically manifests with joint noises, pain and restricted mouth opening. In late stages, it results in severe damage of TMJ structures and development of ankylosis. Osteoarthrosis is a multifactorial disease; the occurrence is associated with TMJ overloading. The cohort included 619 patients [538 women (87%) and 81 men (13%), with average age 40...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27924428/vertiginous-crisis-following-temporomandibular-joint-athrocentesis-a-case-report
#19
Luigi Angelo Vaira, Damiano Soma, Silvio Mario Meloni, Giovanni Dellàversana Orabona, Pasquale Piombino, Giacomo De Riu
Temporomandibular joint arthrocentesis and arthroscopy have recently exceeded open surgeries for disorders that failed to respond to conservative treatment. The efficacy of arthrocentesis in reestablishing normal mouth opening and reducing pain and dysfunctions is now commonly accepted, but in contrast to arthroscopy, there are no large series studies on arthrocentesis complications. We report the major complication occurred in our experience: a case of a patient that complained of a violent vertigo, without hearing disorders, following the procedure...
December 6, 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27918746/use-of-the-universal-pain-assessment-tool-for-evaluating-pain-associated-with-tmd-in-youngsters-with-an-intellectual-disability
#20
G Dugashvili, L Van den Berghe, G Menabde, M Janelidze, L Marks
BACKGROUND: The Universal Pain Assessment Tool (UPAT) was used to assess the level of pain in people with limited communication skills. The UPAT enables clinicians to consult a specialized pain management team more often and lead to earlier interventions. The purpose of this study was to determine, whether the UPAT could be used as an extra tool to collect data on functional TMJ pain and to assess orofacial pain levels related to temporomandibular disorder(s) (TMD) in people with intellectual disabilities (ID)...
January 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
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