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https://www.readbyqxmd.com/read/27803223/international-consensus-on-the-definition-and-classification-of-fibrosis-of-the-knee-joint
#1
N S Kalson, L A Borthwick, D A Mann, D J Deehan, P Lewis, C Mann, M A Mont, R Morgan-Jones, S Oussedik, F M K Williams, A Toms, J N Argenson, J Bellemans, A Bhave, O Furnes, H Gollwitzer, F S Haddad, S Hofmann, V Krenn
AIMS: The aim of this consensus was to develop a definition of post-operative fibrosis of the knee. PATIENTS AND METHODS: An international panel of experts took part in a formal consensus process composed of a discussion phase and three Delphi rounds. RESULTS: Post-operative fibrosis of the knee was defined as a limited range of movement (ROM) in flexion and/or extension, that is not attributable to an osseous or prosthetic block to movement from malaligned, malpositioned or incorrectly sized components, metal hardware, ligament reconstruction, infection (septic arthritis), pain, chronic regional pain syndrome (CRPS) or other specific causes, but due to soft-tissue fibrosis that was not present pre-operatively...
November 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27745829/-treatment-and-progression-of-acute-communautary-osteoarticular-infections-in-healthy-children-a-retrospective-monocentric-study-of-64%C3%A2-patients
#2
A Lemoine, F Baudin, R Vialle, E Grimprel
INTRODUCTION: The prognosis of osteoarticular infections has improved over the past 20 years but it still remains potentially severe. The treatment of these infections has been simplified and shortened. In 2008, the Pediatric Infectious Disease Group (GPIP) established new therapeutic guidelines in order to standardize treatment in France. The aim of this study is to analyze practices in a Parisian hospital and assess the efficacy of this treatment in short and medium terms. MATERIALS AND METHODS: This retrospective study focused on patients older than 3 months, without comorbidities, who were hospitalized for an acute osteoarticular infection in 2012 at Trousseau Hospital (Paris), with a follow-up of at least 4 weeks...
November 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27520996/post-streptococcal-reactive-arthritis-where-are-we-now
#3
Himanshu Pathak, Tarnya Marshall
A 35-year-old man presented with polyarthritis and constitutional symptoms, and a recent history of multiple tick bites and skin rash on trekking holiday. He did not respond to oral doxycycline and cephalexine for presumed Lyme's disease. Further investigation confirmed strongly positive streptococcal serology. There was absence of clinical or echocardiography evidence of heart involvement and immunological screening for inflammatory arthritis was negative. In the absence of other major Jones criteria for acute rheumatic fever, besides polyarthritis and the serological evidence of a recent streptococcal infection, a diagnosis of post-streptococcal reactive arthritis (PSRA) was also made...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27348896/-lyme-disease-clinical-manifestations-and-treatment
#4
Ingo Stock
Lyme disease (Lyme borreliosis) is a systemic infectious disease that can present in a variety of clinical manifestations. The disease is caused by a group of spirochaetes--Borrelia burgdorferi sensu lato or Lyme borrelia--that are transmitted to humans by the bite of Ixodes ticks. Lyme disease is the most common arthropode-borne infectious disease in many European countries including Germany. Early localized infection is typically manifested by an erythema migrans skin lesion, in rarer cases as a borrelial lymphocytoma...
May 2016: Medizinische Monatsschrift Für Pharmazeuten
https://www.readbyqxmd.com/read/27096429/influenza-and-pneumococcal-vaccination-uptake-in-patients-with-rheumatoid-arthritis-treated-with-immunosuppressive-therapy-in-the-uk-a-retrospective-cohort-study-using-data-from-the-clinical-practice-research-datalink
#5
Ruth Costello, Kevin L Winthrop, Stephen R Pye, Benjamin Brown, William G Dixon
INTRODUCTION: Guidelines for the management of rheumatoid arthritis (RA) recommend using influenza and pneumococcal vaccinations to mitigate infection risk. The level of adherence to these guidelines is not well known in the UK. The aims of this study were to describe the uptake of influenza and pneumococcal vaccinations in patients with RA in the UK, to compare the characteristics of those vaccinated to those not vaccinated and to compare vaccination rates across regions of the UK. METHODS: A retrospective cohort study of adults diagnosed with incident RA and treated with non-biologic immunosuppressive therapy, using data from a large primary care database...
2016: PloS One
https://www.readbyqxmd.com/read/27057385/clinical-and-laboratory-predictors-of-articular-disorders-among-hiv-infected-patients-seen-at-teaching-hospital-southeast-nigeria
#6
C C Okwara, G Ozoh, B C Nwatu
BACKGROUND: HIV infection may be associated with different arthropathies that are often underdiagnosed. There is also paucity of reported studies of relationship between clinical and laboratory features of HIV-infected patients and articular disorders. AIMS: To determine the predictors of articular disorders among HIV-infected patients seen at tertiary hospital Nigeria. SUBJECTS AND METHODS: Hospital-based cross-sectional descriptive study...
November 2015: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/27055728/management-of-acute-hve-infection-in-a-patient-treated-with-rituximab-for-rheumatoid-arthritis
#7
Frank Verhoeven, Delphine Weil-Verhoeven, Vincent Di Martino, Clément Prati, Thierry Thevenot, Daniel Wendling
INTRODUCTION: Acute E hepatitis becomes more frequent in immunocompromised patients. No guidelines are available to date for the management of this infection and of the immunosuppressive treatment. METHODS: We report a case of acute E hepatitis treated with ribavirine in a patient known for rheumatoid arthritis and treated with rituximab. CASE: A 51-year-old woman known for rheumatoid arthritis and treated with rituximab was hospitalized for a jaundice secondary to an acute E hepatitis...
October 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/26939612/sustained-moderate-to-high-disease-activity-and-higher-charlson-score-are-predictors-of-incidental-serious-infection-events-in-ra-patients-treated-with-conventional-disease-modifying-anti-rheumatic-drugs-a-cohort-study-in-the-treat-to-target-era
#8
Gretel Galicia-Hernández, Federico Parra-Salcedo, Paulina Ugarte-Martínez, Irazú Contreras-Yáñez, Alfredo Ponce-de-León, Virginia Pascual-Ramos
OBJECTIVES: Rheumatoid arthritis (RA) guidelines have moved toward intensive treatment aimed at remission. Treatment and disease activity are predictors of infections; patients from developing countries have additional predictors that may further impact the infection spectrum. Our aim was to describe serious infection events (SIEs), predictors and impact on RA outcomes, in a cohort of Mexican Mestizo patients. METHODS: Up to February 2015, charts from 176 early RA patients were reviewed by a single data abstracter...
March 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/26639475/simultaneous-quantitation-of-ofloxacin-fexofenadine-hcl-and-diclofenac-potassium-in-affixed-dose-combinative-formulation-by-hplc-uv-method
#9
Faseeh Abdus Salam, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Faisal Sultan, Muhammad Atif Khan, Saeed Manzoor
A high-pressure liquid chromatography (HPLC-UV) based simple and specific method for simultaneous quantitative determination of Ofloxacin, Fexofenadine HCl and Diclofenac Potassium has been developed and validated according to ICH guidelines. Chromatographic separation of the three drugs was carried out on 4.6 x 250 mm x 5 µ Licrospher RP Select B Column, using mobile phase constituted of methanol and phosphate buffer pH 3.5 (650: 350), pH adjusted to 3.5 ± 0.05 with dilute ortho-phosphoric acid and delivered at a flow rate of 1 ml/min...
November 2015: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/26634252/evidence-based-diagnosis-and-treatment-of-macrophage-activation-syndrome-in-systemic-juvenile-idiopathic-arthritis
#10
REVIEW
V Boom, J Anton, P Lahdenne, P Quartier, A Ravelli, N M Wulffraat, S J Vastert
BACKGROUND: Macrophage activation syndrome (MAS) is a severe and potentially lethal complication of several inflammatory diseases but seems particularly linked to systemic juvenile idiopathic arthritis (sJIA). Standardized diagnostic and treatment guidelines for MAS in sJIA are currently lacking. The aim of this systematic literature review was to evaluate currently available literature on diagnostic criteria for MAS in sJIA and provide an overview of possible biomarkers for diagnosis, disease activity and treatment response and recent advances in treatment...
December 3, 2015: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/26562966/pneumococcal-vaccination-in-rheumatic-diseases
#11
REVIEW
Rohini Handa, Ved Chaturvedi, Debashish Danda, V Krishnamurthy
No abstract text is available yet for this article.
April 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/26545940/2015-american-college-of-rheumatology-guideline-for-the-treatment-of-rheumatoid-arthritis
#12
REVIEW
Jasvinder A Singh, Kenneth G Saag, S Louis Bridges, Elie A Akl, Raveendhara R Bannuru, Matthew C Sullivan, Elizaveta Vaysbrot, Christine McNaughton, Mikala Osani, Robert H Shmerling, Jeffrey R Curtis, Daniel E Furst, Deborah Parks, Arthur Kavanaugh, James O'Dell, Charles King, Amye Leong, Eric L Matteson, John T Schousboe, Barbara Drevlow, Seth Ginsberg, James Grober, E William St Clair, Elizabeth Tindall, Amy S Miller, Timothy McAlindon
OBJECTIVE: To develop a new evidence-based, pharmacologic treatment guideline for rheumatoid arthritis (RA). METHODS: We conducted systematic reviews to synthesize the evidence for the benefits and harms of various treatment options. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology to rate the quality of evidence. We employed a group consensus process to grade the strength of recommendations (either strong or conditional)...
January 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/26545825/2015-american-college-of-rheumatology-guideline-for-the-treatment-of-rheumatoid-arthritis
#13
REVIEW
Jasvinder A Singh, Kenneth G Saag, S Louis Bridges, Elie A Akl, Raveendhara R Bannuru, Matthew C Sullivan, Elizaveta Vaysbrot, Christine McNaughton, Mikala Osani, Robert H Shmerling, Jeffrey R Curtis, Daniel E Furst, Deborah Parks, Arthur Kavanaugh, James O'Dell, Charles King, Amye Leong, Eric L Matteson, John T Schousboe, Barbara Drevlow, Seth Ginsberg, James Grober, E William St Clair, Elizabeth Tindall, Amy S Miller, Timothy McAlindon
OBJECTIVE: To develop a new evidence-based, pharmacologic treatment guideline for rheumatoid arthritis (RA). METHODS: We conducted systematic reviews to synthesize the evidence for the benefits and harms of various treatment options. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology to rate the quality of evidence. We employed a group consensus process to grade the strength of recommendations (either strong or conditional)...
January 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/26524851/a-hospital-based-analysis-in-the-department-of-clinical-chemistry-for-the-patients-with-hbv-reactivation-after-anti-cancer-or-immunosuppressive-therapy
#14
Tomoe Matsuzaki, Kumiko Ohkubo, Makiko Yuki, Hironobu Kawashima, Akira Matsunaga
OBJECTIVES: Anti-cancer and immunosuppressive drugs often induce hepatitis B virus (HBV) reactivation, resulting in lethal hepatitis in the worst cases. It is to elucidate the clinical characteristics of the patients in our hospital, who underwent HBV-related examinations to help prevent HBV-associated hepatitis by reactivation during the two-year period after the announcement of new guidelines by the Ministry of Health, Labour and Welfare of Japan in January 2009. STUDY DESIGN: We enrolled 811 patients who were examined for HBs antigen, anti-HBc antibody, anti-HBs antibody and HBV DNA regarding HBV reactivation...
March 2015: Rinsho Byori. the Japanese Journal of Clinical Pathology
https://www.readbyqxmd.com/read/26509064/the-incidence-of-tuberculosis-in-patients-treated-with-certolizumab-pegol-across-indications-impact-of-baseline-skin-test-results-more-stringent-screening-criteria-and-geographic-region
#15
X Mariette, J Vencovsky, O Lortholary, J Gomez-Reino, M de Longueville, P Ralston, M Weinblatt, R van Vollenhoven
OBJECTIVES: We report the incidence of tuberculosis (TB) across certolizumab pegol (CZP) clinical trials in rheumatoid arthritis (RA), psoriasis, psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), before and after the introduction of stricter TB screening. METHODS: TB incidence rates (IRs) were assessed and stratified according to screening guidelines used at the time of CZP trials. Before 2007 (original trials), purified protein derivative (PPD) tuberculin skin test positivity varied according to local standards (induration ≥5 up to ≥20 mm)...
2015: RMD Open
https://www.readbyqxmd.com/read/26497501/biologic-therapy-for-inflammatory-arthritis-and-latent-tuberculosis-real-world-experience-from-a-high-prevalence-area-in-the-united-kingdom
#16
Muhammad K Nisar, Aneesa Rafiq, Andrew J K Östör
Biologic therapies have resulted in a sea change in the management of inflammatory arthritis; however, a higher risk of opportunistic infection, particularly tuberculosis (TB), is well recognised. This has led to the development of TB screening guidelines. The aim of this study was to investigate the prevalence of latent TB in patients prescribed biologic therapy in an endemic area (prevalence of TB 50/100,000) and to assess the risk of subsequent reactivation. Retrospective case note review of all patients with inflammatory arthritis ever prescribed biologic therapy between 1998 and 2014 at our centre...
December 2015: Clinical Rheumatology
https://www.readbyqxmd.com/read/26472415/a-study-of-multiple-causes-of-death-in-rheumatoid-arthritis
#17
Frederico A G Pinheiro, Deborah C C Souza, Emilia I Sato
OBJECTIVE: To evaluate rheumatoid arthritis (RA)-related mortality in the state of São Paulo (Brazil). METHODS: Data from all death certificates (DC) from 1996 to 2010 were analyzed using a multiple cause-of-death method. We compared the results from 2 subperiods (1996-2000 and 2006-2010). RESULTS: We found 3955 DC related to RA - 27.6% with RA as the underlying cause of death (UCD) and 72.4% with RA as the nonunderlying cause of death (NUCD)...
December 2015: Journal of Rheumatology
https://www.readbyqxmd.com/read/26445992/inconsistency-in-the-reporting-of-adverse-events-in-total-ankle-arthroplasty-a-systematic-review-of-the-literature
#18
Jeff Mercer, Murray Penner, Kevin Wing, Alastair S E Younger
BACKGROUND: Systems for classifying complications have been proposed for many surgical subspecialties. The goal of this systematic review was to analyze the number and frequency of different terms used to identify complications in total ankle arthroplasty. We hypothesized that this terminology would be highly variable, supporting a need for a standardized system of reporting. METHODS: Studies that met predefined inclusion/exclusion criteria were analyzed to identify terminology used to describe adverse events...
February 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/26408195/patterns-of-uveitis-at-the-apex-institute-for-eye-care-in-india-results-from-a-prospectively-enrolled-patient-data-base-2011-2013
#19
Pradeep Venkatesh, Varun Gogia, Bhavin Shah, Shikha Gupta, Pradeep Sagar, Satpal Garg
The purpose of the study was to identify the clinical and etiological profile of uveitis at the apex institute for eye care in India. This is a prospective, prevalence study. 980 consecutive patients with uveitis referred to uvea clinic, Dr. RP Centre for Ophthalmic Sciences (Ophthalmology division, All India Institute of Medical Sciences). Demographic data of each patient were noted and a thorough ocular examination including slit lamp examination and dilated fundus evaluation was carried out. OCT and fluorescein angiography were undertaken whenever indicated...
June 2016: International Ophthalmology
https://www.readbyqxmd.com/read/26294972/screening-optimization-of-latent-tuberculosis-infection-in-rheumatoid-arthritis-patients
#20
Bella Mehta, Ekaterini Zapantis, Olga Petryna, Petros Efthimiou
Objective. Rheumatoid arthritis (RA) patients are at increased risk of latent tuberculosis infection (LTBI) but there are no clear guidelines for LTBI screening with Tuberculin Skin Test (TST) or Quantiferon TB Gold testing (QFT-G). Methods. A retrospective study was conducted in a high risk, largely foreign-born, inner city, RA population. After screening 280 RA patients, 134 patients who had both TST and QFT-G testing performed during their initial evaluation were included. Results. Out of 132 RA patients included in our analysis, 50 (37...
2015: Arthritis
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